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Items: 22

1.

Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma.

Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein P, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A.

Leukemia. 2019 Mar 26. doi: 10.1038/s41375-019-0454-4. [Epub ahead of print]

PMID:
30914792
2.

Pharmacologic control of CAR-T cell function using dasatinib.

Weber EW, Lynn RC, Sotillo E, Lattin J, Xu P, Mackall CL.

Blood Adv. 2019 Mar 12;3(5):711-717. doi: 10.1182/bloodadvances.2018028720. No abstract available.

3.

Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion.

Heitzeneder S, Sotillo E, Shern JF, Sindiri S, Xu P, Jones R, Pollak M, Noer PR, Lorette J, Fazli L, Alag A, Meltzer P, Lau C, Conover CA, Oxvig C, Sorensen PH, Maris JM, Khan J, Mackall CL.

J Natl Cancer Inst. 2019 Jan 30. doi: 10.1093/jnci/djy209. [Epub ahead of print]

PMID:
30698726
4.

CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors.

Majzner RG, Theruvath JL, Nellan A, Heitzeneder S, Cui Y, Mount CW, Rietberg SP, Linde MH, Xu P, Rota C, Sotillo E, Labanieh L, Lee DW, Orentas RJ, Dimitrov DS, Zhu Z, Croix BS, Delaidelli A, Sekunova A, Bonvini E, Mitra SS, Quezado MM, Majeti R, Monje M, Sorensen PHB, Maris JM, Mackall CL.

Clin Cancer Res. 2019 Apr 15;25(8):2560-2574. doi: 10.1158/1078-0432.CCR-18-0432. Epub 2019 Jan 17.

PMID:
30655315
5.

CAR T Cell Therapy for Neuroblastoma.

Richards RM, Sotillo E, Majzner RG.

Front Immunol. 2018 Oct 16;9:2380. doi: 10.3389/fimmu.2018.02380. eCollection 2018. Review.

6.

CD19 Alterations Emerging after CD19-Directed Immunotherapy Cause Retention of the Misfolded Protein in the Endoplasmic Reticulum.

Bagashev A, Sotillo E, Tang CH, Black KL, Perazzelli J, Seeholzer SH, Argon Y, Barrett DM, Grupp SA, Hu CC, Thomas-Tikhonenko A.

Mol Cell Biol. 2018 Oct 15;38(21). pii: e00383-18. doi: 10.1128/MCB.00383-18. Print 2018 Nov 1.

7.

Repeated loss of target surface antigen after immunotherapy in primary mediastinal large B cell lymphoma.

Yu H, Sotillo E, Harrington C, Wertheim G, Paessler M, Maude SL, Rheingold SR, Grupp SA, Thomas-Tikhonenko A, Pillai V.

Am J Hematol. 2017 Jan;92(1):E11-E13. doi: 10.1002/ajh.24594. Epub 2016 Nov 21. No abstract available.

8.

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy.

Sotillo E, Barrett DM, Black KL, Bagashev A, Oldridge D, Wu G, Sussman R, Lanauze C, Ruella M, Gazzara MR, Martinez NM, Harrington CT, Chung EY, Perazzelli J, Hofmann TJ, Maude SL, Raman P, Barrera A, Gill S, Lacey SF, Melenhorst JJ, Allman D, Jacoby E, Fry T, Mackall C, Barash Y, Lynch KW, Maris JM, Grupp SA, Thomas-Tikhonenko A.

Cancer Discov. 2015 Dec;5(12):1282-95. doi: 10.1158/2159-8290.CD-15-1020. Epub 2015 Oct 29.

9.

The long reach of noncoding RNAs.

Sotillo E, Thomas-Tikhonenko A.

Nat Genet. 2011 Jun 28;43(7):616-7. doi: 10.1038/ng.870. No abstract available.

10.

Shielding the messenger (RNA): microRNA-based anticancer therapies.

Sotillo E, Thomas-Tikhonenko A.

Pharmacol Ther. 2011 Jul;131(1):18-32. doi: 10.1016/j.pharmthera.2011.04.006. Epub 2011 Apr 14. Review.

11.

Myc overexpression brings out unexpected antiapoptotic effects of miR-34a.

Sotillo E, Laver T, Mellert H, Schelter JM, Cleary MA, McMahon S, Thomas-Tikhonenko A.

Oncogene. 2011 Jun 2;30(22):2587-94. doi: 10.1038/onc.2010.634. Epub 2011 Feb 7.

12.

B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation.

Jayadeva G, Kurimchak A, Garriga J, Sotillo E, Davis AJ, Haines DS, Mumby M, Graña X.

J Biol Chem. 2010 Sep 24;285(39):29863-73. doi: 10.1074/jbc.M110.162354. Epub 2010 Jul 27.

13.

Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells.

Rivadeneira DB, Mayhew CN, Thangavel C, Sotillo E, Reed CA, Graña X, Knudsen ES.

Gastroenterology. 2010 May;138(5):1920-30. doi: 10.1053/j.gastro.2010.01.007. Epub 2010 Jan 25.

14.

Identification of variables that influence brain-dead donors' family groups regarding refusal.

Sotillo E, Montoya E, Martínez V, Paz G, Armas A, Liscano C, Hernández G, Pérez M, Andrade A, Villasmil N, Mollegas L, Hernández E, Milanes CL, Rivas P.

Transplant Proc. 2009 Oct;41(8):3466-70. doi: 10.1016/j.transproceed.2009.09.014.

PMID:
19857773
15.

Coordinated activation of the origin licensing factor CDC6 and CDK2 in resting human fibroblasts expressing SV40 small T antigen and cyclin E.

Sotillo E, Garriga J, Padgaonkar A, Kurimchak A, Cook JG, Graña X.

J Biol Chem. 2009 May 22;284(21):14126-35. doi: 10.1074/jbc.M900687200. Epub 2009 Mar 25.

16.

Cyclin E and SV40 small T antigen cooperate to bypass quiescence and contribute to transformation by activating CDK2 in human fibroblasts.

Sotillo E, Garriga J, Kurimchak A, Graña X.

J Biol Chem. 2008 Apr 25;283(17):11280-92. doi: 10.1074/jbc.M709055200. Epub 2008 Feb 14.

17.

Movement ability of rye terminal neocentromeres.

Puertas MJ, García-Chico R, Sotillo E, González-Sánchez M, Manzanero S.

Cytogenet Genome Res. 2005;109(1-3):120-7.

PMID:
15753567
18.

A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130.

Garriga J, Jayaraman AL, Limón A, Jayadeva G, Sotillo E, Truongcao M, Patsialou A, Wadzinski BE, Graña X.

Cell Cycle. 2004 Oct;3(10):1320-30. Epub 2004 Oct 15. Erratum in: Cell Cycle. 2005 Mar;4(3):e45.

PMID:
15467457
19.

Analysis of polymorphisms of the vitamin D receptor, estrogen receptor, and collagen Ialpha1 genes and their relationship with height in children with bone cancer.

Ruza E, Sotillo E, Sierrasesúmaga L, Azcona C, Patiño-García A.

J Pediatr Hematol Oncol. 2003 Oct;25(10):780-6.

PMID:
14528100
20.
21.

G1 cyclin/cyclin-dependent kinase-coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression.

Calbó J, Parreño M, Sotillo E, Yong T, Mazo A, Garriga J, Grana X.

J Biol Chem. 2002 Dec 27;277(52):50263-74. Epub 2002 Oct 24.

22.

Mite-contaminated foods as a cause of anaphylaxis.

Sanchez-Borges M, Capriles-Hulett A, Fernandez-Caldas E, Suarez-Chacon R, Caballero F, Castillo S, Sotillo E.

J Allergy Clin Immunol. 1997 Jun;99(6 Pt 1):738-43.

PMID:
9215239

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