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Items: 1 to 50 of 96

1.

Imaging the Microstructure of the Human Fetal Heart.

Sosnovik DE, Geva T.

Circ Cardiovasc Imaging. 2018 Oct;11(10):e008298. doi: 10.1161/CIRCIMAGING.118.008298. No abstract available.

PMID:
30354486
2.

Noninvasive Tissue Characterization of Post-Infarction Myocardium.

Sosnovik DE, Tawakol A.

JACC Cardiovasc Imaging. 2018 Sep;11(9):1257-1259. doi: 10.1016/j.jcmg.2017.11.040. No abstract available.

PMID:
30190028
3.

Imaging the Vascular Bone Marrow Niche During Inflammatory Stress.

Vandoorne K, Rohde D, Kim HY, Courties G, Wojtkiewicz G, Honold L, Hoyer FF, Frodermann V, Nayar R, Herisson F, Jung Y, Désogère PA, Vinegoni C, Caravan P, Weissleder R, Sosnovik DE, Lin CP, Swirski FK, Nahrendorf M.

Circ Res. 2018 Aug 3;123(4):415-427. doi: 10.1161/CIRCRESAHA.118.313302.

PMID:
29980569
4.

Multiplexed Optical Imaging of Energy Substrates Reveals That Left Ventricular Hypertrophy Is Associated With Brown Adipose Tissue Activation.

Panagia M, Chen HH, Croteau D, Iris Chen YC, Ran C, Luptak I, Josephson L, Colucci WS, Sosnovik DE.

Circ Cardiovasc Imaging. 2018 Mar;11(3):e007007. doi: 10.1161/CIRCIMAGING.117.007007. Review.

PMID:
29555834
5.

Myocardial Scar Delineation Using Diffusion Tensor Magnetic Resonance Tractography.

Mekkaoui C, Jackowski MP, Kostis WJ, Stoeck CT, Thiagalingam A, Reese TG, Reddy VY, Ruskin JN, Kozerke S, Sosnovik DE.

J Am Heart Assoc. 2018 Feb 2;7(3). pii: e007834. doi: 10.1161/JAHA.117.007834.

6.

PET/MR Imaging of Atherosclerosis: Insights Into Atheroma Structure and Biology.

Tawakol A, Sosnovik DE.

JACC Cardiovasc Imaging. 2018 Feb;11(2 Pt 2):302-304. doi: 10.1016/j.jcmg.2017.12.004. No abstract available.

7.

Cardiac macrophages promote diastolic dysfunction.

Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M.

J Exp Med. 2018 Feb 5;215(2):423-440. doi: 10.1084/jem.20171274. Epub 2018 Jan 16.

8.

Highly potent visnagin derivatives inhibit Cyp1 and prevent doxorubicin cardiotoxicity.

Asnani A, Zheng B, Liu Y, Wang Y, Chen HH, Vohra A, Chi A, Cornella-Taracido I, Wang H, Johns DG, Sosnovik DE, Peterson RT.

JCI Insight. 2018 Jan 11;3(1). pii: 96753. doi: 10.1172/jci.insight.96753. [Epub ahead of print]

9.

Native T1 reference values for nonischemic cardiomyopathies and populations with increased cardiovascular risk: A systematic review and meta-analysis.

van den Boomen M, Slart RHJA, Hulleman EV, Dierckx RAJO, Velthuis BK, van der Harst P, Sosnovik DE, Borra RJH, Prakken NHJ.

J Magn Reson Imaging. 2018 Apr;47(4):891-912. doi: 10.1002/jmri.25885. Epub 2017 Nov 13. Review.

10.

A Manganese-based Alternative to Gadolinium: Contrast-enhanced MR Angiography, Excretion, Pharmacokinetics, and Metabolism.

Gale EM, Wey HY, Ramsay I, Yen YF, Sosnovik DE, Caravan P.

Radiology. 2018 Mar;286(3):865-872. doi: 10.1148/radiol.2017170977. Epub 2017 Nov 8.

11.

Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome.

Ferrari M, Jain IH, Goldberger O, Rezoagli E, Thoonen R, Cheng KH, Sosnovik DE, Scherrer-Crosbie M, Mootha VK, Zapol WM.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4241-E4250. doi: 10.1073/pnas.1621511114. Epub 2017 May 8. Erratum in: Proc Natl Acad Sci U S A. 2018 Jan 30;:. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4894-E4896.

12.

Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis.

Shea BS, Probst CK, Brazee PL, Rotile NJ, Blasi F, Weinreb PH, Black KE, Sosnovik DE, Van Cott EM, Violette SM, Caravan P, Tager AM.

JCI Insight. 2017 May 4;2(9). pii: 86608. doi: 10.1172/jci.insight.86608. [Epub ahead of print]

13.

Theranostic Nucleic Acid Binding Nanoprobe Exerts Anti-inflammatory and Cytoprotective Effects in Ischemic Injury.

Chen HH, Yuan H, Cho H, Feng Y, Ngoy S, Kumar AT, Liao R, Chao W, Josephson L, Sosnovik DE.

Theranostics. 2017 Feb 8;7(4):814-825. doi: 10.7150/thno.17366. eCollection 2017.

14.

Evaluation of antitumor activity and cardiac toxicity of a bone-targeted ph-sensitive liposomal formulation in a bone metastasis tumor model in mice.

Dos Santos Ferreira D, Jesus de Oliveira Pinto BL, Kumar V, Cardoso VN, Fernandes SO, Souza CM, Cassali GD, Moore A, Sosnovik DE, Farrar CT, Leite EA, Alves RJ, de Oliveira MC, Guimarães AR, Caravan P.

Nanomedicine. 2017 Jul;13(5):1693-1701. doi: 10.1016/j.nano.2017.03.005. Epub 2017 Mar 23.

15.

Diffusion Tractography of the Entire Left Ventricle by Using Free-breathing Accelerated Simultaneous Multisection Imaging.

Mekkaoui C, Reese TG, Jackowski MP, Cauley SF, Setsompop K, Bhat H, Sosnovik DE.

Radiology. 2017 Mar;282(3):850-856. doi: 10.1148/radiol.2016152613. Epub 2016 Sep 28.

16.

Microstructural characterization of myocardial infarction with optical coherence tractography and two-photon microscopy.

Goergen CJ, Chen HH, Sakadžić S, Srinivasan VJ, Sosnovik DE.

Physiol Rep. 2016 Sep;4(18). pii: e12894. doi: 10.14814/phy2.12894.

17.

Functional and anatomical characterization of brown adipose tissue in heart failure with blood oxygen level dependent magnetic resonance.

Panagia M, Chen YC, Chen HH, Ernande L, Chen C, Chao W, Kwong K, Scherrer-Crosbie M, Sosnovik DE.

NMR Biomed. 2016 Jul;29(7):978-84. doi: 10.1002/nbm.3557. Epub 2016 May 26.

18.

Diffusion MRI in the heart.

Mekkaoui C, Reese TG, Jackowski MP, Bhat H, Sosnovik DE.

NMR Biomed. 2017 Mar;30(3). doi: 10.1002/nbm.3426. Epub 2015 Oct 20. Review.

19.

Heat-Induced Radiolabeling of Nanoparticles for Monocyte Tracking by PET.

Normandin MD, Yuan H, Wilks MQ, Chen HH, Kinsella JM, Cho H, Guehl NJ, Absi-Halabi N, Hosseini SM, El Fakhri G, Sosnovik DE, Josephson L.

Angew Chem Int Ed Engl. 2015 Oct 26;54(44):13002-6. doi: 10.1002/anie.201505525. Epub 2015 Sep 14.

20.

Imaging Lymphoid Cell Death In Vivo During Polymicrobial Sepsis.

Zou L, Chen HH, Li D, Xu G, Feng Y, Chen C, Wang L, Sosnovik DE, Chao W.

Crit Care Med. 2015 Nov;43(11):2303-12. doi: 10.1097/CCM.0000000000001254.

PMID:
26335111
21.

Seeing What We Build--The Need for New Imaging Techniques in Myocardial Regeneration.

Sosnovik DE.

J Am Heart Assoc. 2015 Jul 27;4(7). pii: e002306. doi: 10.1161/JAHA.115.002306. No abstract available.

22.

Functional brown adipose tissue limits cardiomyocyte injury and adverse remodeling in catecholamine-induced cardiomyopathy.

Thoonen R, Ernande L, Cheng J, Nagasaka Y, Yao V, Miranda-Bezerra A, Chen C, Chao W, Panagia M, Sosnovik DE, Puppala D, Armoundas AA, Hindle A, Bloch KD, Buys ES, Scherrer-Crosbie M.

J Mol Cell Cardiol. 2015 Jul;84:202-11. doi: 10.1016/j.yjmcc.2015.05.002. Epub 2015 May 9.

23.

Cytoprotective nanoparticles by conjugation of a polyhis tagged annexin V to a nanoparticle drug.

Chen HH, Yuan H, Cho H, Sosnovik DE, Josephson L.

Nanoscale. 2015 Feb 14;7(6):2255-9. doi: 10.1039/c4nr06861k.

24.

Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase.

Liu Y, Asnani A, Zou L, Bentley VL, Yu M, Wang Y, Dellaire G, Sarkar KS, Dai M, Chen HH, Sosnovik DE, Shin JT, Haber DA, Berman JN, Chao W, Peterson RT.

Sci Transl Med. 2014 Dec 10;6(266):266ra170. doi: 10.1126/scitranslmed.3010189.

25.

In vivo nanoparticle assessment of pathological endothelium predicts the development of inflow stenosis in murine arteriovenous fistula.

Cui J, Kessinger CW, McCarthy JR, Sosnovik DE, Libby P, Thadhani RI, Jaffer FA.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):189-96. doi: 10.1161/ATVBAHA.114.304483. Epub 2014 Nov 13.

26.

Dual-phase cardiac diffusion tensor imaging with strain correction.

Stoeck CT, Kalinowska A, von Deuster C, Harmer J, Chan RW, Niemann M, Manka R, Atkinson D, Sosnovik DE, Mekkaoui C, Kozerke S.

PLoS One. 2014 Sep 5;9(9):e107159. doi: 10.1371/journal.pone.0107159. eCollection 2014.

27.

Direct coupling of annexin A5 to VSOP yields small, protein-covered nanoprobes for MR imaging of apoptosis.

Figge L, Appler F, Chen HH, Sosnovik DE, Schnorr J, Seitz O, Taupitz M, Hamm B, Schellenberger E.

Contrast Media Mol Imaging. 2014 Jul-Aug;9(4):291-9. doi: 10.1002/cmmi.1575.

PMID:
24706613
28.

Microstructural impact of ischemia and bone marrow-derived cell therapy revealed with diffusion tensor magnetic resonance imaging tractography of the heart in vivo.

Sosnovik DE, Mekkaoui C, Huang S, Chen HH, Dai G, Stoeck CT, Ngoy S, Guan J, Wang R, Kostis WJ, Jackowski MP, Wedeen VJ, Kozerke S, Liao R.

Circulation. 2014 Apr 29;129(17):1731-41. doi: 10.1161/CIRCULATIONAHA.113.005841. Epub 2014 Mar 11.

29.

Role of extracellular RNA and TLR3-Trif signaling in myocardial ischemia-reperfusion injury.

Chen C, Feng Y, Zou L, Wang L, Chen HH, Cai JY, Xu JM, Sosnovik DE, Chao W.

J Am Heart Assoc. 2014 Jan 3;3(1):e000683. doi: 10.1161/JAHA.113.000683.

30.

Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria.

Yuan H, Cho H, Chen HH, Panagia M, Sosnovik DE, Josephson L.

Chem Commun (Camb). 2013 Nov 14;49(88):10361-3. doi: 10.1039/c3cc45802d.

PMID:
24072060
31.

Diffusion MRI tractography of the developing human fetal heart.

Mekkaoui C, Porayette P, Jackowski MP, Kostis WJ, Dai G, Sanders S, Sosnovik DE.

PLoS One. 2013 Aug 26;8(8):e72795. doi: 10.1371/journal.pone.0072795. eCollection 2013.

32.

Molecular magnetic resonance imaging of pulmonary fibrosis in mice.

Caravan P, Yang Y, Zachariah R, Schmitt A, Mino-Kenudson M, Chen HH, Sosnovik DE, Dai G, Fuchs BC, Lanuti M.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):1120-6. doi: 10.1165/rcmb.2013-0039OC.

33.

Imaging DNA with fluorochrome bearing metals.

Cho H, Guo Y, Sosnovik DE, Josephson L.

Inorg Chem. 2013 Nov 4;52(21):12216-22. doi: 10.1021/ic400404g. Epub 2013 May 6. Review.

34.

Fluorescence tomography of rapamycin-induced autophagy and cardioprotection in vivo.

Chen HH, Mekkaoui C, Cho H, Ngoy S, Marinelli B, Waterman P, Nahrendorf M, Liao R, Josephson L, Sosnovik DE.

Circ Cardiovasc Imaging. 2013 May 1;6(3):441-7. doi: 10.1161/CIRCIMAGING.112.000074. Epub 2013 Mar 28.

35.

Molecular MRI of the Cardiovascular System in the Post-NSF Era.

Sosnovik DE, Caravan P.

Curr Cardiovasc Imaging Rep. 2013 Feb 1;6(1):61-68. Epub 2012 Nov 29.

36.

Classification of coronary atherosclerotic plaques ex vivo with T1, T2, and ultrashort echo time CMR.

Károlyi M, Seifarth H, Liew G, Schlett CL, Maurovich-Horvat P, Stolzmann P, Dai G, Huang S, Goergen CJ, Nakano M, Otsuka F, Virmani R, Hoffmann U, Sosnovik DE.

JACC Cardiovasc Imaging. 2013 Apr;6(4):466-74. doi: 10.1016/j.jcmg.2012.09.015. Epub 2013 Mar 14.

37.

Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems.

Cho H, Alcantara D, Yuan H, Sheth RA, Chen HH, Huang P, Andersson SB, Sosnovik DE, Mahmood U, Josephson L.

ACS Nano. 2013 Mar 26;7(3):2032-41. doi: 10.1021/nn305962n. Epub 2013 Feb 7.

38.

Reproducibility of in-vivo diffusion tensor cardiovascular magnetic resonance in hypertrophic cardiomyopathy.

McGill LA, Ismail TF, Nielles-Vallespin S, Ferreira P, Scott AD, Roughton M, Kilner PJ, Ho SY, McCarthy KP, Gatehouse PD, de Silva R, Speier P, Feiweier T, Mekkaoui C, Sosnovik DE, Prasad SK, Firmin DN, Pennell DJ.

J Cardiovasc Magn Reson. 2012 Dec 24;14:86. doi: 10.1186/1532-429X-14-86. Erratum in: J Cardiovasc Magn Reson. 2013;15:22.

39.

Adult cardiac progenitor cell aggregates exhibit survival benefit both in vitro and in vivo.

Bauer M, Kang L, Qiu Y, Wu J, Peng M, Chen HH, Camci-Unal G, Bayomy AF, Sosnovik DE, Khademhosseini A, Liao R.

PLoS One. 2012;7(11):e50491. doi: 10.1371/journal.pone.0050491. Epub 2012 Nov 30.

40.

Fiber architecture in remodeled myocardium revealed with a quantitative diffusion CMR tractography framework and histological validation.

Mekkaoui C, Huang S, Chen HH, Dai G, Reese TG, Kostis WJ, Thiagalingam A, Maurovich-Horvat P, Ruskin JN, Hoffmann U, Jackowski MP, Sosnovik DE.

J Cardiovasc Magn Reson. 2012 Oct 12;14:70. doi: 10.1186/1532-429X-14-70.

41.

Optical coherence tractography using intrinsic contrast.

Goergen CJ, Radhakrishnan H, Sakadžić S, Mandeville ET, Lo EH, Sosnovik DE, Srinivasan VJ.

Opt Lett. 2012 Sep 15;37(18):3882-4.

42.

In vivo diffusion tensor MRI of the human heart: reproducibility of breath-hold and navigator-based approaches.

Nielles-Vallespin S, Mekkaoui C, Gatehouse P, Reese TG, Keegan J, Ferreira PF, Collins S, Speier P, Feiweier T, de Silva R, Jackowski MP, Pennell DJ, Sosnovik DE, Firmin D.

Magn Reson Med. 2013 Aug;70(2):454-65. doi: 10.1002/mrm.24488. Epub 2012 Sep 21. Erratum in: Magn Reson Med. 2014 Aug;72(2):599.

44.

Science to practice: how will myocardial inflammation be imaged with MR imaging?

Sosnovik DE, Nahrendorf M, Caravan P.

Radiology. 2012 Aug;264(2):309-11. doi: 10.1148/radiol.12121094.

PMID:
22821689
45.

Fluorochrome-functionalized magnetic nanoparticles for high-sensitivity monitoring of the polymerase chain reaction by magnetic resonance.

Alcantara D, Guo Y, Yuan H, Goergen CJ, Chen HH, Cho H, Sosnovik DE, Josephson L.

Angew Chem Int Ed Engl. 2012 Jul 9;51(28):6904-7. doi: 10.1002/anie.201201661. Epub 2012 Jun 8.

46.

In vivo fluorescence lifetime detection of an activatable probe in infarcted myocardium.

Goergen CJ, Chen HH, Bogdanov A, Sosnovik DE, Kumar AT.

J Biomed Opt. 2012 May;17(5):056001. doi: 10.1117/1.JBO.17.5.056001.

47.

Theranostic Imaging of the Kinases and Proteases that Modulate Cell Death and Survival.

Chen HH, Yuan H, Josephson L, Sosnovik DE.

Theranostics. 2012;2(2):148-55. doi: 10.7150/thno.4077. Epub 2012 Feb 8.

48.

A Novel Transgenic Mouse Model of Cardiac Hypertrophy and Atrial Fibrillation.

Rosenberg MA, Das S, Quintero Pinzon P, Knight AC, Sosnovik DE, Ellinor PT, Rosenzweig A.

J Atr Fibrillation. 2012 Feb 2;4(5):415. doi: 10.4022/jafib.415. eCollection 2012 Feb-Mar. Review.

49.

Molecular MRI of acute necrosis with a novel DNA-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium.

Huang S, Chen HH, Yuan H, Dai G, Schuhle DT, Mekkaoui C, Ngoy S, Liao R, Caravan P, Josephson L, Sosnovik DE.

Circ Cardiovasc Imaging. 2011 Nov;4(6):729-37. doi: 10.1161/CIRCIMAGING.111.966374. Epub 2011 Aug 11.

50.

Science to practice: will magnetic guidance of microbubbles play a role in clinical molecular imaging?

Nahrendorf M, Sosnovik DE.

Radiology. 2011 Aug;260(2):309-10. doi: 10.1148/radiol.11111017.

PMID:
21778448

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