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Items: 34

1.

Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts.

Ma R, Martínez-Ramírez AS, Borders TL, Gao F, Sosa-Pineda B.

Elife. 2020 Mar 10;9. pii: e46206. doi: 10.7554/eLife.46206.

2.

Complex bile duct network formation within liver decellularized extracellular matrix hydrogels.

Lewis PL, Su J, Yan M, Meng F, Glaser SS, Alpini GD, Green RM, Sosa-Pineda B, Shah RN.

Sci Rep. 2018 Aug 15;8(1):12220. doi: 10.1038/s41598-018-30433-6.

3.

ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer.

Drosos Y, Escobar D, Chiang MY, Roys K, Valentine V, Valentine MB, Rehg JE, Sahai V, Begley LA, Ye J, Paul L, McKinnon PJ, Sosa-Pineda B.

Sci Rep. 2017 Sep 11;7(1):11144. doi: 10.1038/s41598-017-11661-8.

4.

Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation.

Drosos Y, Neale G, Ye J, Paul L, Kuliyev E, Maitra A, Means AL, Washington MK, Rehg J, Finkelstein DB, Sosa-Pineda B.

Neoplasia. 2016 Mar;18(3):172-84. doi: 10.1016/j.neo.2016.02.002.

5.

Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-Cells.

Paul L, Walker EM, Drosos Y, Cyphert HA, Neale G, Stein R, South J, Grosveld G, Herrera PL, Sosa-Pineda B.

Diabetes. 2016 Mar;65(3):687-98. doi: 10.2337/db15-0713. Epub 2015 Dec 2.

6.

Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction.

Shi C, Washington MK, Chaturvedi R, Drosos Y, Revetta FL, Weaver CJ, Buzhardt E, Yull FE, Blackwell TS, Sosa-Pineda B, Whitehead RH, Beauchamp RD, Wilson KT, Means AL.

Lab Invest. 2014 Apr;94(4):409-21. doi: 10.1038/labinvest.2014.10. Epub 2014 Feb 17.

7.

Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment.

Seth A, Ye J, Yu N, Guez F, Bedford DC, Neale GA, Cordi S, Brindle PK, Lemaigre FP, Kaestner KH, Sosa-Pineda B.

Development. 2014 Feb;141(3):538-47. doi: 10.1242/dev.099481.

8.

Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas.

Suissa Y, Magenheim J, Stolovich-Rain M, Hija A, Collombat P, Mansouri A, Sussel L, Sosa-Pineda B, McCracken K, Wells JM, Heller RS, Dor Y, Glaser B.

PLoS One. 2013 Aug 5;8(8):e70397. doi: 10.1371/journal.pone.0070397. Print 2013.

9.

The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis.

Evangelou K, Bartkova J, Kotsinas A, Pateras IS, Liontos M, Velimezi G, Kosar M, Liloglou T, Trougakos IP, Dyrskjot L, Andersen CL, Papaioannou M, Drosos Y, Papafotiou G, Hodny Z, Sosa-Pineda B, Wu XR, Klinakis A, Ørntoft T, Lukas J, Bartek J, Gorgoulis VG.

Cell Death Differ. 2013 Nov;20(11):1485-97. doi: 10.1038/cdd.2013.76. Epub 2013 Jul 12.

10.

Hippo signaling maintains the phenotype of pancreatic acinar cells.

Sosa-Pineda B.

Gastroenterology. 2013 Jun;144(7):1345-8. doi: 10.1053/j.gastro.2013.04.027. Epub 2013 Apr 24. No abstract available.

PMID:
23623964
11.

Dynamic distribution of claudin proteins in pancreatic epithelia undergoing morphogenesis or neoplastic transformation.

Westmoreland JJ, Drosos Y, Kelly J, Ye J, Means AL, Washington MK, Sosa-Pineda B.

Dev Dyn. 2012 Mar;241(3):583-94. doi: 10.1002/dvdy.23740. Epub 2012 Jan 31.

12.

Pancreas-specific deletion of Prox1 affects development and disrupts homeostasis of the exocrine pancreas.

Westmoreland JJ, Kilic G, Sartain C, Sirma S, Blain J, Rehg J, Harvey N, Sosa-Pineda B.

Gastroenterology. 2012 Apr;142(4):999-1009.e6. doi: 10.1053/j.gastro.2011.12.007. Epub 2011 Dec 13.

13.

Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium.

Magenheim J, Klein AM, Stanger BZ, Ashery-Padan R, Sosa-Pineda B, Gu G, Dor Y.

Dev Biol. 2011 Nov 1;359(1):26-36. doi: 10.1016/j.ydbio.2011.08.006. Epub 2011 Aug 17.

14.

Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.

Raum JC, Hunter CS, Artner I, Henderson E, Guo M, Elghazi L, Sosa-Pineda B, Ogihara T, Mirmira RG, Sussel L, Stein R.

Mol Cell Biol. 2010 Sep;30(17):4234-44. doi: 10.1128/MCB.01396-09. Epub 2010 Jun 28.

15.

Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression.

Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Pierreux CE, Lemaigre FP, Foley J, Jetten AM.

Mol Cell Biol. 2009 Dec;29(24):6366-79. doi: 10.1128/MCB.01259-09. Epub 2009 Oct 5. Erratum in: Mol Cell Biol. 2010 Apr;30(7):1864. Pierreux, Christophe E [added]; Lemaigre, Frederic P [added].

16.

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells.

Collombat P, Xu X, Ravassard P, Sosa-Pineda B, Dussaud S, Billestrup N, Madsen OD, Serup P, Heimberg H, Mansouri A.

Cell. 2009 Aug 7;138(3):449-62. doi: 10.1016/j.cell.2009.05.035.

17.

Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells.

Westmoreland JJ, Wang Q, Bouzaffour M, Baker SJ, Sosa-Pineda B.

Dev Biol. 2009 Oct 1;334(1):285-98. doi: 10.1016/j.ydbio.2009.07.030. Epub 2009 Jul 25.

18.

Ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum.

Wang Q, Elghazi L, Martin S, Martins I, Srinivasan RS, Geng X, Sleeman M, Collombat P, Houghton J, Sosa-Pineda B.

Dev Dyn. 2008 Jan;237(1):51-61.

19.

Identification of a mammalian mitochondrial porphyrin transporter.

Krishnamurthy PC, Du G, Fukuda Y, Sun D, Sampath J, Mercer KE, Wang J, Sosa-Pineda B, Murti KG, Schuetz JD.

Nature. 2006 Oct 5;443(7111):586-9. Epub 2006 Sep 27.

PMID:
17006453
20.
21.

MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells.

Artner I, Le Lay J, Hang Y, Elghazi L, Schisler JC, Henderson E, Sosa-Pineda B, Stein R.

Diabetes. 2006 Feb;55(2):297-304.

22.

Prox1 activity controls pancreas morphogenesis and participates in the production of "secondary transition" pancreatic endocrine cells.

Wang J, Kilic G, Aydin M, Burke Z, Oliver G, Sosa-Pineda B.

Dev Biol. 2005 Oct 1;286(1):182-94.

23.

The gene Pax4 is an essential regulator of pancreatic beta-cell development.

Sosa-Pineda B.

Mol Cells. 2004 Dec 31;18(3):289-94. Review.

24.

Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development.

Prado CL, Pugh-Bernard AE, Elghazi L, Sosa-Pineda B, Sussel L.

Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2924-9. Epub 2004 Feb 17.

25.

The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation.

Wang J, Elghazi L, Parker SE, Kizilocak H, Asano M, Sussel L, Sosa-Pineda B.

Dev Biol. 2004 Feb 1;266(1):178-89.

26.

IFN-gamma overexpression within the pancreas is not sufficient to rescue Pax4, Pax6, and Pdx-1 mutant mice from death.

Krakowski M, Yeung B, Abdelmalik R, Good A, Mocnik L, Sosa-Pineda B, St-Onge L, Gruss P, Sarvetnick N.

Pancreas. 2000 Nov;21(4):399-406.

PMID:
11075995
27.

Hepatocyte migration during liver development requires Prox1.

Sosa-Pineda B, Wigle JT, Oliver G.

Nat Genet. 2000 Jul;25(3):254-5.

PMID:
10888866
28.

Pax 4 and 6 regulate gastrointestinal endocrine cell development.

Larsson LI, St-Onge L, Hougaard DM, Sosa-Pineda B, Gruss P.

Mech Dev. 1998 Dec;79(1-2):153-9.

29.

Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas.

St-Onge L, Sosa-Pineda B, Chowdhury K, Mansouri A, Gruss P.

Nature. 1997 May 22;387(6631):406-9.

PMID:
9163426
30.

The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas.

Sosa-Pineda B, Chowdhury K, Torres M, Oliver G, Gruss P.

Nature. 1997 Mar 27;386(6623):399-402.

PMID:
9121556
31.

Prox 1, a prospero-related homeobox gene expressed during mouse development.

Oliver G, Sosa-Pineda B, Geisendorf S, Spana EP, Doe CQ, Gruss P.

Mech Dev. 1993 Nov;44(1):3-16.

PMID:
7908825
32.

Homeoboxes in flatworms.

Oliver G, Vispo M, Mailhos A, Martínez C, Sosa-Pineda B, Fielitz W, Ehrlich R.

Gene. 1992 Nov 16;121(2):337-42.

PMID:
1359988
33.

Cloning and characterization of cDNA encoding canine alpha-L-iduronidase. mRNA deficiency in mucopolysaccharidosis I dog.

Stoltzfus LJ, Sosa-Pineda B, Moskowitz SM, Menon KP, Dlott B, Hooper L, Teplow DB, Shull RM, Neufeld EF.

J Biol Chem. 1992 Apr 5;267(10):6570-5.

34.

Apparent generation of a segmented mRNA from two separate tandem gene families in Trypanosoma cruzi.

Gonzalez A, Lerner TJ, Huecas M, Sosa-Pineda B, Nogueira N, Lizardi PM.

Nucleic Acids Res. 1985 Aug 26;13(16):5789-804.

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