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Items: 8

1.

Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis.

Weckbach LT, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, Pick R, Salvermoser M, Czermak T, Pircher J, Sorrelle N, Migliorini M, Strickland DK, Klingel K, Brinkmann V, Abu Abed U, Eriksson U, Massberg S, Brunner S, Walzog B.

J Exp Med. 2019 Feb 4;216(2):350-368. doi: 10.1084/jem.20181102. Epub 2019 Jan 15.

PMID:
30647120
2.

Improved Multiplex Immunohistochemistry for Immune Microenvironment Evaluation of Mouse Formalin-Fixed, Paraffin-Embedded Tissues.

Sorrelle N, Ganguly D, Dominguez ATA, Zhang Y, Huang H, Dahal LN, Burton N, Ziemys A, Brekken RA.

J Immunol. 2019 Jan 1;202(1):292-299. doi: 10.4049/jimmunol.1800878. Epub 2018 Dec 3.

PMID:
30510069
3.

Sitravatinib potentiates immune checkpoint blockade in refractory cancer models.

Du W, Huang H, Sorrelle N, Brekken RA.

JCI Insight. 2018 Nov 2;3(21). pii: 124184. doi: 10.1172/jci.insight.124184. [Epub ahead of print]

4.

Cyclooxygenase-2 Inhibition Potentiates the Efficacy of Vascular Endothelial Growth Factor Blockade and Promotes an Immune Stimulatory Microenvironment in Preclinical Models of Pancreatic Cancer.

Zhang Y, Kirane A, Huang H, Sorrelle NB, Burrows FJ, Dellinger MT, Brekken RA.

Mol Cancer Res. 2019 Feb;17(2):348-355. doi: 10.1158/1541-7786.MCR-18-0427. Epub 2018 Oct 17.

PMID:
30333153
5.

Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer.

Ludwig KF, Du W, Sorrelle NB, Wnuk-Lipinska K, Topalovski M, Toombs JE, Cruz VH, Yabuuchi S, Rajeshkumar NV, Maitra A, Lorens JB, Brekken RA.

Cancer Res. 2018 Jan 1;78(1):246-255. doi: 10.1158/0008-5472.CAN-17-1973. Epub 2017 Nov 27.

6.

From top to bottom: midkine and pleiotrophin as emerging players in immune regulation.

Sorrelle N, Dominguez ATA, Brekken RA.

J Leukoc Biol. 2017 Aug;102(2):277-286. doi: 10.1189/jlb.3MR1116-475R. Epub 2017 Mar 29. Review.

7.

Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis.

Kirane A, Ludwig KF, Sorrelle N, Haaland G, Sandal T, Ranaweera R, Toombs JE, Wang M, Dineen SP, Micklem D, Dellinger MT, Lorens JB, Brekken RA.

Cancer Res. 2015 Sep 15;75(18):3699-705. doi: 10.1158/0008-5472.CAN-14-2887-T. Epub 2015 Jul 23.

8.

Enzyme functional evolution through improved catalysis of ancestrally nonpreferred substrates.

Huang R, Hippauf F, Rohrbeck D, Haustein M, Wenke K, Feike J, Sorrelle N, Piechulla B, Barkman TJ.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2966-71. doi: 10.1073/pnas.1019605109. Epub 2012 Feb 6.

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