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Items: 1 to 50 of 171

1.

Single cell transcriptomic analysis of human mesenchymal stem cells reveals limited heterogeneity.

Huang Y, Li Q, Zhang K, Hu M, Wang Y, Du L, Lin L, Li S, Sorokin L, Melino G, Shi Y, Wang Y.

Cell Death Dis. 2019 May 8;10(5):368. doi: 10.1038/s41419-019-1583-4.

2.

Inhibition of platelet GPVI induces intratumor hemorrhage and increases efficacy of chemotherapy in mice.

Volz J, Mammadova-Bach E, Gil-Pulido J, Nandigama R, Remer K, Sorokin L, Zernecke A, Abrams SI, Ergün S, Henke E, Nieswandt B.

Blood. 2019 Apr 5. pii: blood.2018877043. doi: 10.1182/blood.2018877043. [Epub ahead of print]

PMID:
30952674
3.

New in Vivo Compatible Matrix Metalloproteinase (MMP)-2 and MMP-9 Inhibitors.

Beutel B, Song J, Konken CP, Korpos E, Schinor B, Gerwien H, Vidyadharan R, Burmeister M, Li L, Haufe G, Sorokin L.

Bioconjug Chem. 2018 Nov 21;29(11):3715-3725. doi: 10.1021/acs.bioconjchem.8b00618. Epub 2018 Oct 24.

PMID:
30277751
4.

Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus.

Breuer J, Korpos E, Hannocks MJ, Schneider-Hohendorf T, Song J, Zondler L, Herich S, Flanagan K, Korn T, Zarbock A, Kuhlmann T, Sorokin L, Wiendl H, Schwab N.

J Neuroinflammation. 2018 Aug 22;15(1):236. doi: 10.1186/s12974-018-1276-4.

5.

Temporal window for detection of inflammatory disease using dynamic cell tracking with time-lapse MRI.

Masthoff M, Gran S, Zhang X, Wachsmuth L, Bietenbeck M, Helfen A, Heindel W, Sorokin L, Roth J, Eisenblätter M, Wildgruber M, Faber C.

Sci Rep. 2018 Jun 22;8(1):9563. doi: 10.1038/s41598-018-27879-z.

6.

Staphylococcus aureus requires less virulence to establish an infection in diabetic hosts.

Tuchscherr L, Korpos È, van de Vyver H, Findeisen C, Kherkheulidze S, Siegmund A, Deinhardt-Emmer S, Bach O, Rindert M, Mellmann A, Sunderkötter C, Peters G, Sorokin L, Löffler B.

Int J Med Microbiol. 2018 Oct;308(7):761-769. doi: 10.1016/j.ijmm.2018.05.004. Epub 2018 May 22.

PMID:
29843979
7.

CD99L2 deficiency inhibits leukocyte entry into the central nervous system and ameliorates neuroinflammation.

Samus M, Seelige R, Schäfer K, Sorokin L, Vestweber D.

J Leukoc Biol. 2018 Oct;104(4):787-797. doi: 10.1002/JLB.1A0617-228R. Epub 2018 May 23.

PMID:
29791026
8.

Fractone Bulbs Derive from Ependymal Cells and Their Laminin Composition Influence the Stem Cell Niche in the Subventricular Zone.

Nascimento MA, Sorokin L, Coelho-Sampaio T.

J Neurosci. 2018 Apr 18;38(16):3880-3889. doi: 10.1523/JNEUROSCI.3064-17.2018. Epub 2018 Mar 12.

9.

Bone marrow laminins influence hematopoietic stem and progenitor cell cycling and homing to the bone marrow.

Susek KH, Korpos E, Huppert J, Wu C, Savelyeva I, Rosenbauer F, Müller-Tidow C, Koschmieder S, Sorokin L.

Matrix Biol. 2018 Apr;67:47-62. doi: 10.1016/j.matbio.2018.01.007. Epub 2018 Jan 31.

PMID:
29360499
10.

Molecular characterization of perivascular drainage pathways in the murine brain.

Hannocks MJ, Pizzo ME, Huppert J, Deshpande T, Abbott NJ, Thorne RG, Sorokin L.

J Cereb Blood Flow Metab. 2018 Apr;38(4):669-686. doi: 10.1177/0271678X17749689. Epub 2017 Dec 28. Erratum in: J Cereb Blood Flow Metab. 2018 Aug;38(8):1384.

11.

[A rare case of metastatic tumor of heart from bladder cancer].

Koval AP, Kukharchik GA, Dikarev KV, Minkin SR, Sorokin LA.

Kardiologiia. 2017 SJan;57(S1):367-372. Russian.

PMID:
29276910
12.

The gelatinases, MMP-2 and MMP-9, as fine tuners of neuroinflammatory processes.

Hannocks MJ, Zhang X, Gerwien H, Chashchina A, Burmeister M, Korpos E, Song J, Sorokin L.

Matrix Biol. 2019 Jan;75-76:102-113. doi: 10.1016/j.matbio.2017.11.007. Epub 2017 Nov 21. Review.

PMID:
29158162
13.

Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of delivery.

Pizzo ME, Wolak DJ, Kumar NN, Brunette E, Brunnquell CL, Hannocks MJ, Abbott NJ, Meyerand ME, Sorokin L, Stanimirovic DB, Thorne RG.

J Physiol. 2018 Feb 1;596(3):445-475. doi: 10.1113/JP275105. Epub 2017 Dec 18.

14.

Laminin-511 and -521-based matrices for efficient ex vivo-expansion of human limbal epithelial progenitor cells.

Polisetti N, Sorokin L, Okumura N, Koizumi N, Kinoshita S, Kruse FE, Schlötzer-Schrehardt U.

Sci Rep. 2017 Jul 11;7(1):5152. doi: 10.1038/s41598-017-04916-x.

15.

Endothelial basement membrane laminin 511 is essential for shear stress response.

Di Russo J, Luik AL, Yousif L, Budny S, Oberleithner H, Hofschröer V, Klingauf J, van Bavel E, Bakker EN, Hellstrand P, Bhattachariya A, Albinsson S, Pincet F, Hallmann R, Sorokin LM.

EMBO J. 2017 May 15;36(10):1464. doi: 10.15252/embj.201797000. No abstract available.

16.

Cell-matrix signals specify bone endothelial cells during developmental osteogenesis.

Langen UH, Pitulescu ME, Kim JM, Enriquez-Gasca R, Sivaraj KK, Kusumbe AP, Singh A, Di Russo J, Bixel MG, Zhou B, Sorokin L, Vaquerizas JM, Adams RH.

Nat Cell Biol. 2017 Mar;19(3):189-201. doi: 10.1038/ncb3476. Epub 2017 Feb 20.

17.

Endothelial Basement Membrane Laminin 511 Contributes to Endothelial Junctional Tightness and Thereby Inhibits Leukocyte Transmigration.

Song J, Zhang X, Buscher K, Wang Y, Wang H, Di Russo J, Li L, Lütke-Enking S, Zarbock A, Stadtmann A, Striewski P, Wirth B, Kuzmanov I, Wiendl H, Schulte D, Vestweber D, Sorokin L.

Cell Rep. 2017 Jan 31;18(5):1256-1269. doi: 10.1016/j.celrep.2016.12.092.

18.

Endothelial basement membrane laminin 511 is essential for shear stress response.

Di Russo J, Luik AL, Yousif L, Budny S, Oberleithner H, Hofschröer V, Klingauf J, van Bavel E, Bakker EN, Hellstrand P, Bhattachariya A, Albinsson S, Pincet F, Hallmann R, Sorokin LM.

EMBO J. 2017 Jan 17;36(2):183-201. doi: 10.15252/embj.201694756. Epub 2016 Dec 9. Erratum in: EMBO J. 2017 May 15;36(10 ):1464.

19.

Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier.

Gerwien H, Hermann S, Zhang X, Korpos E, Song J, Kopka K, Faust A, Wenning C, Gross CC, Honold L, Melzer N, Opdenakker G, Wiendl H, Schäfers M, Sorokin L.

Sci Transl Med. 2016 Nov 9;8(364):364ra152.

PMID:
27831901
20.

Vascular laminins in physiology and pathology.

Di Russo J, Hannocks MJ, Luik AL, Song J, Zhang X, Yousif L, Aspite G, Hallmann R, Sorokin L.

Matrix Biol. 2017 Jan;57-58:140-148. doi: 10.1016/j.matbio.2016.06.008. Epub 2016 Jul 2. Review. No abstract available.

PMID:
27378388
21.

Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis.

Fleger-Weckmann A, Üstün Y, Kloepper J, Paus R, Bloch W, Chen ZL, Wegner J, Sorokin L, Langbein L, Eckes B, Zigrino P, Krieg T, Nischt R.

Matrix Biol. 2016 Dec;56:42-56. doi: 10.1016/j.matbio.2016.05.002. Epub 2016 May 25.

PMID:
27234308
22.

Laminin α5 in the keratinocyte basement membrane is required for epidermal-dermal intercommunication.

Wegner J, Loser K, Apsite G, Nischt R, Eckes B, Krieg T, Werner S, Sorokin L.

Matrix Biol. 2016 Dec;56:24-41. doi: 10.1016/j.matbio.2016.05.001. Epub 2016 May 24.

PMID:
27234307
23.

Protection from septic peritonitis by rapid neutrophil recruitment through omental high endothelial venules.

Buscher K, Wang H, Zhang X, Striewski P, Wirth B, Saggu G, Lütke-Enking S, Mayadas TN, Ley K, Sorokin L, Song J.

Nat Commun. 2016 Mar 4;7:10828. doi: 10.1038/ncomms10828.

24.

Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.

Ridder DA, Wenzel J, Müller K, Töllner K, Tong XK, Assmann JC, Stroobants S, Weber T, Niturad C, Fischer L, Lembrich B, Wolburg H, Grand'Maison M, Papadopoulos P, Korpos E, Truchetet F, Rades D, Sorokin LM, Schmidt-Supprian M, Bedell BJ, Pasparakis M, Balschun D, D'Hooge R, Löscher W, Hamel E, Schwaninger M.

J Exp Med. 2015 Sep 21;212(10):1529-49. doi: 10.1084/jem.20150165. Epub 2015 Sep 7.

25.

The regulation of immune cell trafficking by the extracellular matrix.

Hallmann R, Zhang X, Di Russo J, Li L, Song J, Hannocks MJ, Sorokin L.

Curr Opin Cell Biol. 2015 Oct;36:54-61. doi: 10.1016/j.ceb.2015.06.006. Epub 2015 Jul 17. Review.

PMID:
26189064
26.

Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke.

Zinnhardt B, Viel T, Wachsmuth L, Vrachimis A, Wagner S, Breyholz HJ, Faust A, Hermann S, Kopka K, Faber C, Dollé F, Pappata S, Planas AM, Tavitian B, Schäfers M, Sorokin LM, Kuhlmann MT, Jacobs AH.

J Cereb Blood Flow Metab. 2015 Nov;35(11):1711-21. doi: 10.1038/jcbfm.2015.149. Epub 2015 Jul 1.

27.

[Features of the heart wound by non-lethal kinetic weapons].

Gumanenko EK, Lazarev SM, Artiukhov SV, Maliar AV, Chernysh AV, Sorokin LA, Noskov AA.

Vestn Khir Im I I Grek. 2015;174(1):65-6. Russian. No abstract available.

PMID:
25962298
28.

The motorized RhoGAP myosin IXb (Myo9b) in leukocytes regulates experimental autoimmune encephalomyelitis induction and recovery.

Liu Z, Xu Y, Zhang X, Song J, Sorokin L, Bähler M.

J Neuroimmunol. 2015 May 15;282:25-32. doi: 10.1016/j.jneuroim.2015.03.014. Epub 2015 Mar 14.

PMID:
25903725
29.

Focal MMP-2 and MMP-9 activity at the blood-brain barrier promotes chemokine-induced leukocyte migration.

Song J, Wu C, Korpos E, Zhang X, Agrawal SM, Wang Y, Faber C, Schäfers M, Körner H, Opdenakker G, Hallmann R, Sorokin L.

Cell Rep. 2015 Feb 24;10(7):1040-54. doi: 10.1016/j.celrep.2015.01.037. Epub 2015 Feb 19.

30.

The laminin response in inflammatory bowel disease: protection or malignancy?

Spenlé C, Lefebvre O, Lacroute J, Méchine-Neuville A, Barreau F, Blottière HM, Duclos B, Arnold C, Hussenet T, Hemmerlé J, Gullberg D, Kedinger M, Sorokin L, Orend G, Simon-Assmann P.

PLoS One. 2014 Oct 27;9(10):e111336. doi: 10.1371/journal.pone.0111336. eCollection 2014.

31.

Extracellular matrix components in the pathogenesis of type 1 diabetes.

Bogdani M, Korpos E, Simeonovic CJ, Parish CR, Sorokin L, Wight TN.

Curr Diab Rep. 2014 Dec;14(12):552. doi: 10.1007/s11892-014-0552-7. Review.

32.

Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.

Seano G, Chiaverina G, Gagliardi PA, di Blasio L, Puliafito A, Bouvard C, Sessa R, Tarone G, Sorokin L, Helley D, Jain RK, Serini G, Bussolino F, Primo L.

Nat Cell Biol. 2014 Oct;16(10):931-41, 1-8. doi: 10.1038/ncb3036. Epub 2014 Sep 14.

33.

VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells.

Schneider-Hohendorf T, Rossaint J, Mohan H, Böning D, Breuer J, Kuhlmann T, Gross CC, Flanagan K, Sorokin L, Vestweber D, Zarbock A, Schwab N, Wiendl H.

J Exp Med. 2014 Aug 25;211(9):1833-46. doi: 10.1084/jem.20140540. Epub 2014 Aug 18.

34.

Extracellular deposition of matrilin-2 controls the timing of the myogenic program during muscle regeneration.

Deák F, Mátés L, Korpos E, Zvara A, Szénási T, Kiricsi M, Mendler L, Keller-Pintér A, Ozsvári B, Juhász H, Sorokin L, Dux L, Mermod N, Puskás LG, Kiss I.

J Cell Sci. 2014 Aug 1;127(Pt 15):3240-56. doi: 10.1242/jcs.141556. Epub 2014 Jun 3.

35.

Syndecan-1, a cell surface proteoglycan, negatively regulates initial leukocyte recruitment to the brain across the choroid plexus in murine experimental autoimmune encephalomyelitis.

Zhang X, Wu C, Song J, Götte M, Sorokin L.

J Immunol. 2013 Nov 1;191(9):4551-61. doi: 10.4049/jimmunol.1300931. Epub 2013 Sep 27.

37.

Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival.

Song J, Lokmic Z, Lämmermann T, Rolf J, Wu C, Zhang X, Hallmann R, Hannocks MJ, Horn N, Ruegg MA, Sonnenberg A, Georges-Labouesse E, Winkler TH, Kearney JF, Cardell S, Sorokin L.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2915-24. doi: 10.1073/pnas.1218131110. Epub 2013 Jul 11.

38.

The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury.

Enzmann G, Mysiorek C, Gorina R, Cheng YJ, Ghavampour S, Hannocks MJ, Prinz V, Dirnagl U, Endres M, Prinz M, Beschorner R, Harter PN, Mittelbronn M, Engelhardt B, Sorokin L.

Acta Neuropathol. 2013 Mar;125(3):395-412. doi: 10.1007/s00401-012-1076-3. Epub 2012 Dec 27.

39.

Laminin isoforms in endothelial and perivascular basement membranes.

Yousif LF, Di Russo J, Sorokin L.

Cell Adh Migr. 2013 Jan-Feb;7(1):101-10. doi: 10.4161/cam.22680. Epub 2012 Dec 21. Review.

40.

In vivo processing of CXCL5 (LIX) by matrix metalloproteinase (MMP)-2 and MMP-9 promotes early neutrophil recruitment in IL-1β-induced peritonitis.

Song J, Wu C, Zhang X, Sorokin LM.

J Immunol. 2013 Jan 1;190(1):401-10. doi: 10.4049/jimmunol.1202286. Epub 2012 Dec 7.

41.

The peri-islet basement membrane, a barrier to infiltrating leukocytes in type 1 diabetes in mouse and human.

Korpos É, Kadri N, Kappelhoff R, Wegner J, Overall CM, Weber E, Holmberg D, Cardell S, Sorokin L.

Diabetes. 2013 Feb;62(2):531-42. doi: 10.2337/db12-0432. Epub 2012 Nov 8.

42.

Rescue from acute neuroinflammation by pharmacological chemokine-mediated deviation of leukocytes.

Berghmans N, Heremans H, Li S, Martens E, Matthys P, Sorokin L, Van Damme J, Opdenakker G.

J Neuroinflammation. 2012 Oct 25;9:243. doi: 10.1186/1742-2094-9-243.

43.

Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation.

Steiner E, Enzmann GU, Lin S, Ghavampour S, Hannocks MJ, Zuber B, Rüegg MA, Sorokin L, Engelhardt B.

Glia. 2012 Nov;60(11):1646-59. doi: 10.1002/glia.22383. Epub 2012 Jul 10.

PMID:
22782669
44.

The epidermal basement membrane is a composite of separate laminin- or collagen IV-containing networks connected by aggregated perlecan, but not by nidogens.

Behrens DT, Villone D, Koch M, Brunner G, Sorokin L, Robenek H, Bruckner-Tuderman L, Bruckner P, Hansen U.

J Biol Chem. 2012 May 25;287(22):18700-9. doi: 10.1074/jbc.M111.336073. Epub 2012 Apr 9.

45.

CD4(+) type II NKT cells mediate ICOS and programmed death-1-dependent regulation of type 1 diabetes.

Kadri N, Korpos E, Gupta S, Briet C, Löfbom L, Yagita H, Lehuen A, Boitard C, Holmberg D, Sorokin L, Cardell SL.

J Immunol. 2012 Apr 1;188(7):3138-49. doi: 10.4049/jimmunol.1101390. Epub 2012 Feb 27.

46.

Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo.

Stenzel D, Franco CA, Estrach S, Mettouchi A, Sauvaget D, Rosewell I, Schertel A, Armer H, Domogatskaya A, Rodin S, Tryggvason K, Collinson L, Sorokin L, Gerhardt H.

EMBO Rep. 2011 Oct 28;12(11):1135-43. doi: 10.1038/embor.2011.194.

47.

Glycosaminoglycan mimicry by COAM reduces melanoma growth through chemokine induction and function.

Piccard H, Berghmans N, Korpos E, Dillen C, Aelst IV, Li S, Martens E, Liekens S, Noppen S, Damme JV, Sorokin L, Opdenakker G.

Int J Cancer. 2012 Aug 15;131(4):E425-36. doi: 10.1002/ijc.26465. Epub 2011 Nov 9.

48.

MMP2-9 cleavage of dystroglycan alters the size and molecular composition of Schwann cell domains.

Court FA, Zambroni D, Pavoni E, Colombelli C, Baragli C, Figlia G, Sorokin L, Ching W, Salzer JL, Wrabetz L, Feltri ML.

J Neurosci. 2011 Aug 24;31(34):12208-17. doi: 10.1523/JNEUROSCI.0141-11.2011.

49.

Monoclonal antibodies reveal the alteration of the rhodocetin structure upon α2β1 integrin binding.

Bracht T, Figueiredo de Rezende F, Stetefeld J, Sorokin LM, Eble JA.

Biochem J. 2011 Nov 15;440(1):1-11. doi: 10.1042/BJ20110584.

PMID:
21774787
50.

Regional differences in the expression of laminin isoforms during mouse neural tube development.

Copp AJ, Carvalho R, Wallace A, Sorokin L, Sasaki T, Greene ND, Ybot-Gonzalez P.

Matrix Biol. 2011 May;30(4):301-9. doi: 10.1016/j.matbio.2011.04.001. Epub 2011 Apr 16.

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