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Items: 5

1.

INTERACTIONS BETWEEN MARAVIROC AND THE ABCB1, ABCG2 AND ABCC2 TRANSPORTERS: AN IMPORTANT ROLE IN TRANSPLACENTAL PHARMACOKINETICS.

Tupova L, Ceckova M, Ambrus C, Sorf A, Ptackova Z, Gaborik Z, Staud F.

Drug Metab Dispos. 2019 Jul 2. pii: dmd.119.087684. doi: 10.1124/dmd.119.087684. [Epub ahead of print]

2.

Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance.

Hofman J, Sorf A, Vagiannis D, Sucha S, Novotna E, Kammerer S, Küpper JH, Ceckova M, Staud F.

Drug Metab Dispos. 2019 Jul;47(7):699-709. doi: 10.1124/dmd.119.086975. Epub 2019 May 8.

PMID:
31068367
3.

Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters.

Sorf A, Novotna E, Hofman J, Morell A, Staud F, Wsol V, Ceckova M.

Biochem Pharmacol. 2019 May;163:290-298. doi: 10.1016/j.bcp.2019.02.035. Epub 2019 Feb 28.

PMID:
30826329
4.

Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro.

Sorf A, Hofman J, Kučera R, Staud F, Ceckova M.

Biochem Pharmacol. 2018 Aug;154:10-17. doi: 10.1016/j.bcp.2018.04.013. Epub 2018 Apr 16.

PMID:
29673999
5.

In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?

Soukup O, Korabecny J, Malinak D, Nepovimova E, Pham NL, Musilek K, Hrabinova M, Hepnarova V, Dolezal R, Pavek P, Jost P, Kobrlova T, Jankockova J, Gorecki L, Psotka M, Nguyen TD, Box K, Outhwaite B, Ceckova M, Sorf A, Jun D, Kuca K.

Med Chem. 2018;14(3):281-292. doi: 10.2174/1573406414666180112105657.

PMID:
29332594

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