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Items: 1 to 50 of 373

1.

Integrative Transcriptomics Reveals Sexually Dimorphic Control of the Cholinergic/Neurokine Interface in Schizophrenia and Bipolar Disorder.

Lobentanzer S, Hanin G, Klein J, Soreq H.

Cell Rep. 2019 Oct 15;29(3):764-777.e5. doi: 10.1016/j.celrep.2019.09.017.

2.

Modulation of hippocampal neuronal resilience during aging by the Hsp70/Hsp90 co-chaperone STI1.

Lackie RE, Razzaq AR, Farhan SMK, Qiu LR, Moshitzky G, Beraldo FH, Lopes MH, Maciejewski A, Gros R, Fan J, Choy WY, Greenberg DS, Martins VR, Duennwald ML, Lerch JP, Soreq H, Prado VF, Prado MAM.

J Neurochem. 2019 Sep 28. doi: 10.1111/jnc.14882. [Epub ahead of print]

PMID:
31562773
3.

Whole blood microRNA expression associated with stroke: Results from the Framingham Heart Study.

Salinas J, Lin H, Aparico HJ, Huan T, Liu C, Rong J, Beiser A, Himali JJ, Freedman JE, Larson MG, Rosand J, Soreq H, Levy D, Seshadri S.

PLoS One. 2019 Aug 8;14(8):e0219261. doi: 10.1371/journal.pone.0219261. eCollection 2019.

4.

Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome.

Tejera D, Mercan D, Sanchez-Caro JM, Hanan M, Greenberg D, Soreq H, Latz E, Golenbock D, Heneka MT.

EMBO J. 2019 Sep 2;38(17):e101064. doi: 10.15252/embj.2018101064. Epub 2019 Jul 30.

5.

NEAT1 is overexpressed in Parkinson's disease substantia nigra and confers drug-inducible neuroprotection from oxidative stress.

Simchovitz A, Hanan M, Niederhoffer N, Madrer N, Yayon N, Bennett ER, Greenberg DS, Kadener S, Soreq H.

FASEB J. 2019 Oct;33(10):11223-11234. doi: 10.1096/fj.201900830R. Epub 2019 Jul 17.

6.

Current understanding of fear learning and memory in humans and animal models and the value of a linguistic approach for analyzing fear learning and memory in humans.

Raber J, Arzy S, Bertolus JB, Depue B, Haas HE, Hofmann SG, Kangas M, Kensinger E, Lowry CA, Marusak HA, Minnier J, Mouly AM, Mühlberger A, Norrholm SD, Peltonen K, Pinna G, Rabinak C, Shiban Y, Soreq H, van der Kooij MA, Lowe L, Weingast LT, Yamashita P, Boutros SW.

Neurosci Biobehav Rev. 2019 Oct;105:136-177. doi: 10.1016/j.neubiorev.2019.03.015. Epub 2019 Apr 7. Review.

7.

Reply: TDP-43 mutations increase HNRNP A1-7B through gain of splicing function.

Tétreault M, Deshaies JE, Semmler S, Sidibé H, Shkreta L, Volkening K, Soreq H, Strong MJ, Chabot B, Vande Velde C.

Brain. 2018 Dec 1;141(12):e84. doi: 10.1093/brain/awy261. No abstract available.

PMID:
30364932
8.

Glial responses during epileptogenesis in Mus musculus point to potential therapeutic targets.

Kalozoumi G, Kel-Margoulis O, Vafiadaki E, Greenberg D, Bernard H, Soreq H, Depaulis A, Sanoudou D.

PLoS One. 2018 Aug 16;13(8):e0201742. doi: 10.1371/journal.pone.0201742. eCollection 2018.

9.

Victims of war-Psychoendocrine evidence for the impact of traumatic stress on psychological well-being of adolescents growing up during the Israeli-Palestinian conflict.

Shaheen M, Schindler L, Saar-Ashkenazy R, Bani Odeh K, Soreq H, Friedman A, Kirschbaum C.

Psychophysiology. 2018 Aug 13:e13271. doi: 10.1111/psyp.13271. [Epub ahead of print]

PMID:
30101980
10.

Molecular Regulatory Pathways Link Sepsis With Metabolic Syndrome: Non-coding RNA Elements Underlying the Sepsis/Metabolic Cross-Talk.

Meydan C, Bekenstein U, Soreq H.

Front Mol Neurosci. 2018 Jun 5;11:189. doi: 10.3389/fnmol.2018.00189. eCollection 2018.

11.

TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.

Deshaies JE, Shkreta L, Moszczynski AJ, Sidibé H, Semmler S, Fouillen A, Bennett ER, Bekenstein U, Destroismaisons L, Toutant J, Delmotte Q, Volkening K, Stabile S, Aulas A, Khalfallah Y, Soreq H, Nanci A, Strong MJ, Chabot B, Vande Velde C.

Brain. 2018 May 1;141(5):1320-1333. doi: 10.1093/brain/awy062.

12.

Intensify3D: Normalizing signal intensity in large heterogenic image stacks.

Yayon N, Dudai A, Vrieler N, Amsalem O, London M, Soreq H.

Sci Rep. 2018 Mar 9;8(1):4311. doi: 10.1038/s41598-018-22489-1.

13.

Correction: Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression Profiles.

Pinho R, Guedes LC, Soreq L, Lobo PP, Mestre T, Coelho M, Rosa MM, Gonçalves N, Wales P, Mendes T, Gerhardt E, Fahlbusch C, Bonifati V, Bonin M, Miltenberger-Miltényi G, Borovecki F, Soreq H, Ferreira JJ, Outeiro TF.

PLoS One. 2017 Dec 28;12(12):e0190552. doi: 10.1371/journal.pone.0190552. eCollection 2017.

14.

Building Bridges through Science.

Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, al'Absi M, Arain F, Arango-Lasprilla JC, Atasoy D, Avila J, Badawi A, Bading H, Baig AM, Baleriola J, Belmonte C, Bertocchi I, Betz H, Blakemore C, Blanke O, Boehm-Sturm P, Bonhoeffer T, Bonifazi P, Brose N, Campolongo P, Celikel T, Chang CC, Chang TY, Citri A, Cline HT, Cortes JM, Cullen K, Dean K, Delgado-Garcia JM, Desroches M, Disterhoft JF, Dowling JE, Draguhn A, El-Khamisy SF, El Manira A, Enam SA, Encinas JM, Erramuzpe A, Esteban JA, Fariñas I, Fischer E, Fukunaga I, Gabilondo I, Ganten D, Gidon A, Gomez-Esteban JC, Greengard P, Grinevich V, Gruart A, Guillemin R, Hariri AR, Hassan B, Häusser M, Hayashi Y, Hussain NK, Jabbar AA, Jaber M, Jahn R, Janahi EM, Kabbaj M, Kettenmann H, Kindt M, Knafo S, Köhr G, Komai S, Krugers H, Kuhn B, Ghazal NL, Larkum ME, London M, Lutz B, Matute C, Martinez-Millan L, Maroun M, McGaugh J, Moustafa AA, Nasim A, Nave KA, Neher E, Nikolich K, Outeiro T, Palmer LM, Penagarikano O, Perez-Otano I, Pfaff DW, Poucet B, Rahman AU, Ramos-Cabrer P, Rashidy-Pour A, Roberts RJ, Rodrigues S, Sanes JR, Schaefer AT, Segal M, Segev I, Shafqat S, Siddiqui NA, Soreq H, Soriano-García E, Spanagel R, Sprengel R, Stuart G, Südhof TC, Tønnesen J, Treviño M, Uthman BM, Venter JC, Verkhratsky A, Weiss C, Wiesel TN, Yaksi E, Yizhar O, Young LJ, Young P, Zawia NH, Zugaza JL, Hasan MT.

Neuron. 2017 Nov 15;96(4):730-735. doi: 10.1016/j.neuron.2017.09.028.

15.

Genome-Wide MicroRNA Analysis Implicates miR-30b/d in the Etiology of Alopecia Areata.

Tafazzoli A, Forstner AJ, Broadley D, Hofmann A, Redler S, Petukhova L, Giehl KA, Kruse R, Blaumeiser B, Böhm M, Bertolini M, Rossi A, Garcia Bartels N, Lutz G, Wolff H, Blume-Peytavi U, Soreq H, Christiano AM, Botchkareva NV, Nöthen MM, Betz RC.

J Invest Dermatol. 2018 Mar;138(3):549-556. doi: 10.1016/j.jid.2017.09.046. Epub 2017 Dec 6.

16.

Alexander George Karczmar (1917-2017).

Soreq H, Silman I.

J Neurochem. 2017 Dec;143(5):609-611. doi: 10.1111/jnc.14219. Epub 2017 Oct 13.

17.

Neuronal-expressed microRNA-targeted pseudogenes compete with coding genes in the human brain.

Barbash S, Simchovitz A, Buchman AS, Bennett DA, Shifman S, Soreq H.

Transl Psychiatry. 2017 Aug 8;7(8):e1199. doi: 10.1038/tp.2017.163.

18.

The Stress-Responding miR-132-3p Shows Evolutionarily Conserved Pathway Interactions.

Haviv R, Oz E, Soreq H.

Cell Mol Neurobiol. 2018 Jan;38(1):141-153. doi: 10.1007/s10571-017-0515-z. Epub 2017 Jun 30.

19.

Alzheimer's brains show inter-related changes in RNA and lipid metabolism.

Barbash S, Garfinkel BP, Maoz R, Simchovitz A, Nadorp B, Guffanti A, Bennett ER, Nadeau C, Türk A, Paul L, Reda T, Li Y, Buchman AS, Greenberg DS, Seitz A, Bennett DA, Giavalisco P, Soreq H.

Neurobiol Dis. 2017 Oct;106:1-13. doi: 10.1016/j.nbd.2017.06.008. Epub 2017 Jun 17.

20.

Dynamic changes in murine forebrain miR-211 expression associate with cholinergic imbalances and epileptiform activity.

Bekenstein U, Mishra N, Milikovsky DZ, Hanin G, Zelig D, Sheintuch L, Berson A, Greenberg DS, Friedman A, Soreq H.

Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4996-E5005. doi: 10.1073/pnas.1701201114. Epub 2017 Jun 5.

21.

Alzheimer's Disease and ncRNAs.

Maoz R, Garfinkel BP, Soreq H.

Adv Exp Med Biol. 2017;978:337-361. doi: 10.1007/978-3-319-53889-1_18. Review.

PMID:
28523555
22.

miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression.

Hanin G, Yayon N, Tzur Y, Haviv R, Bennett ER, Udi S, Krishnamoorthy YR, Kotsiliti E, Zangen R, Efron B, Tam J, Pappo O, Shteyer E, Pikarsky E, Heikenwalder M, Greenberg DS, Soreq H.

Gut. 2018 Jun;67(6):1124-1134. doi: 10.1136/gutjnl-2016-312869. Epub 2017 Apr 5.

23.

Personalized genetics of the cholinergic blockade of neuroinflammation.

Simchovitz A, Heneka MT, Soreq H.

J Neurochem. 2017 Aug;142 Suppl 2:178-187. doi: 10.1111/jnc.13928. Epub 2017 Mar 21. Review.

24.

Antisense miR-132 blockade via the AChE-R splice variant mitigates cortical inflammation.

Mishra N, Friedson L, Hanin G, Bekenstein U, Volovich M, Bennett ER, Greenberg DS, Soreq H.

Sci Rep. 2017 Feb 17;7:42755. doi: 10.1038/srep42755.

25.

Mutant α-Synuclein Overexpression Induces Stressless Pacemaking in Vagal Motoneurons at Risk in Parkinson's Disease.

Lasser-Katz E, Simchovitz A, Chiu WH, Oertel WH, Sharon R, Soreq H, Roeper J, Goldberg JA.

J Neurosci. 2017 Jan 4;37(1):47-57. doi: 10.1523/JNEUROSCI.1079-16.2016.

26.

CircRNAs in the brain.

Hanan M, Soreq H, Kadener S.

RNA Biol. 2017 Aug 3;14(8):1028-1034. doi: 10.1080/15476286.2016.1255398. Epub 2016 Nov 28. Review.

27.

Ameliorating Active Ulcerative Colitis via an Orally Available Toll-Like Receptor-9 Modifier: A Prospective Open-Label, Multicenter Phase II Trial.

Dotan I, Levy-Nissenbaum E, Chowers Y, Fich A, Israeli E, Adar T, Shteingart S, Soreq H, Goldin E.

Dig Dis Sci. 2016 Nov;61(11):3246-3254. Epub 2016 Aug 29.

PMID:
27572942
28.

MicroRNA Regulators of Anxiety and Metabolic Disorders.

Meydan C, Shenhar-Tsarfaty S, Soreq H.

Trends Mol Med. 2016 Sep;22(9):798-812. doi: 10.1016/j.molmed.2016.07.001. Epub 2016 Aug 3. Review.

PMID:
27496210
29.

HP1BP3 expression determines maternal behavior and offspring survival.

Garfinkel BP, Arad S, Neuner SM, Netser S, Wagner S, Kaczorowski CC, Rosen CJ, Gal M, Soreq H, Orly J.

Genes Brain Behav. 2016 Sep;15(7):678-88. doi: 10.1111/gbb.12312.

30.

Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression Profiles.

Pinho R, Guedes LC, Soreq L, Lobo PP, Mestre T, Coelho M, Rosa MM, Gonçalves N, Wales P, Mendes T, Gerhardt E, Fahlbusch C, Bonifati V, Bonin M, Miltenberger-Miltényi G, Borovecki F, Soreq H, Ferreira JJ, F Outeiro T.

PLoS One. 2016 Jun 20;11(6):e0157852. doi: 10.1371/journal.pone.0157852. eCollection 2016. Erratum in: PLoS One. 2017 Dec 28;12 (12 ):e0190552.

31.

Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology.

Kolisnyk B, Al-Onaizi M, Soreq L, Barbash S, Bekenstein U, Haberman N, Hanin G, Kish MT, Souza da Silva J, Fahnestock M, Ule J, Soreq H, Prado VF, Prado MAM.

Cereb Cortex. 2017 Jul 1;27(7):3553-3567. doi: 10.1093/cercor/bhw177.

PMID:
27312991
32.

Cholinergic Regulation of hnRNPA2/B1 Translation by M1 Muscarinic Receptors.

Kolisnyk B, Al-Onaizi MA, Xu J, Parfitt GM, Ostapchenko VG, Hanin G, Soreq H, Prado MA, Prado VF.

J Neurosci. 2016 Jun 8;36(23):6287-96. doi: 10.1523/JNEUROSCI.4614-15.2016.

33.

Weakened Cholinergic Blockade of Inflammation Associates with Diabetes-Related Depression.

Shenhar-Tsarfaty S, Toker S, Shapira I, Rogowski O, Berliner S, Ritov Y, Soreq H.

Mol Med. 2016 Sep;22:156-161. doi: 10.2119/molmed.2016.00067. Epub 2016 Apr 4.

34.

Photocatalytic Reactive Oxygen Species Formation by Semiconductor-Metal Hybrid Nanoparticles. Toward Light-Induced Modulation of Biological Processes.

Waiskopf N, Ben-Shahar Y, Galchenko M, Carmel I, Moshitzky G, Soreq H, Banin U.

Nano Lett. 2016 Jul 13;16(7):4266-73. doi: 10.1021/acs.nanolett.6b01298. Epub 2016 May 31.

PMID:
27224678
35.

Intensified vmPFC surveillance over PTSS under perturbed microRNA-608/AChE interaction.

Lin T, Simchovitz A, Shenhar-Tsarfaty S, Vaisvaser S, Admon R, Hanin G, Hanan M, Kliper E, Bar-Haim Y, Shomron N, Fernandez G, Lubin G, Fruchter E, Hendler T, Soreq H.

Transl Psychiatry. 2016 May 3;6:e801. doi: 10.1038/tp.2016.70.

36.

Molecular Mechanisms Regulating LPS-Induced Inflammation in the Brain.

Lykhmus O, Mishra N, Koval L, Kalashnyk O, Gergalova G, Uspenska K, Komisarenko S, Soreq H, Skok M.

Front Mol Neurosci. 2016 Mar 8;9:19. doi: 10.3389/fnmol.2016.00019. eCollection 2016.

37.

Transcriptome profiling in Parkinson's leukocytes: from early diagnostics to neuroimmune therapeutic prospects.

Simchovitz A, Soreq L, Soreq H.

Curr Opin Pharmacol. 2016 Feb;26:102-9. doi: 10.1016/j.coph.2015.10.007. Epub 2015 Nov 21. Review.

PMID:
26609801
38.

Corrigendum: Acute stress facilitates long-lasting changes in cholinergic gene expression.

Kaufer D, Friedman A, Seidman S, Soreq H.

Nature. 2016 Mar 3;531(7592):126. doi: 10.1038/nature16180. Epub 2015 Nov 25. No abstract available.

PMID:
26605528
39.

Analyzing alternative splicing data of splice junction arrays from Parkinson patients' leukocytes before and after deep brain stimulation as compared with control donors.

Soreq L, Salomonis N, Israel Z, Bergman H, Soreq H.

Genom Data. 2015 Jul 16;5:340-3. doi: 10.1016/j.gdata.2015.07.014. eCollection 2015 Sep.

40.

Whole transcriptome RNA sequencing data from blood leukocytes derived from Parkinson's disease patients prior to and following deep brain stimulation treatment.

Soreq L, Salomonis N, Guffanti A, Bergman H, Israel Z, Soreq H.

Genom Data. 2014 Nov 22;3:57-60. doi: 10.1016/j.gdata.2014.11.009. eCollection 2015 Mar.

41.

Functional segregation of voltage-activated calcium channels in motoneurons of the dorsal motor nucleus of the vagus.

Cooper G, Lasser-Katz E, Simchovitz A, Sharon R, Soreq H, Surmeier DJ, Goldberg JA.

J Neurophysiol. 2015 Sep;114(3):1513-20. doi: 10.1152/jn.00432.2014. Epub 2015 Jul 8.

42.

Checks and balances on cholinergic signaling in brain and body function.

Soreq H.

Trends Neurosci. 2015 Jul;38(7):448-58. doi: 10.1016/j.tins.2015.05.007. Epub 2015 Jun 20. Review.

PMID:
26100140
43.

Preclinical and first-in-human evaluation of PRX-105, a PEGylated, plant-derived, recombinant human acetylcholinesterase-R.

Atsmon J, Brill-Almon E, Nadri-Shay C, Chertkoff R, Alon S, Shaikevich D, Volokhov I, Haim KY, Bartfeld D, Shulman A, Ruderfer I, Ben-Moshe T, Shilovitzky O, Soreq H, Shaaltiel Y.

Toxicol Appl Pharmacol. 2015 Sep 15;287(3):202-9. doi: 10.1016/j.taap.2015.06.004. Epub 2015 Jun 4.

PMID:
26051873
44.

Gut feeling: MicroRNA discriminators of the intestinal TLR9-cholinergic links.

Nadorp B, Soreq H.

Int Immunopharmacol. 2015 Nov;29(1):8-14. doi: 10.1016/j.intimp.2015.04.058. Epub 2015 May 20.

45.

Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions?

Blohberger J, Kunz L, Einwang D, Berg U, Berg D, Ojeda SR, Dissen GA, Fröhlich T, Arnold GJ, Soreq H, Lara H, Mayerhofer A.

Cell Death Dis. 2015 Mar 12;6:e1685. doi: 10.1038/cddis.2015.51.

46.

MicroRNA-target interactions in neurodegenerative diseases.

Soreq H.

Springerplus. 2015 Jun 12;4(Suppl 1):L1. doi: 10.1186/2193-1801-4-S1-L1. eCollection 2015. No abstract available.

47.

Fear and C-reactive protein cosynergize annual pulse increases in healthy adults.

Shenhar-Tsarfaty S, Yayon N, Waiskopf N, Shapira I, Toker S, Zaltser D, Berliner S, Ritov Y, Soreq H.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E467-71. doi: 10.1073/pnas.1418264112. Epub 2014 Dec 22.

48.

Tumor necrosis factor-α and interleukin-6 concentrations in cerebrospinal fluid of dogs after seizures.

Merbl Y, Sommer A, Chai O, Aroch I, Zimmerman G, Friedman A, Soreq H, Shamir MH.

J Vet Intern Med. 2014 Nov-Dec;28(6):1775-81. doi: 10.1111/jvim.12462. Epub 2014 Oct 10.

49.

Novel roles of non-coding brain RNAs in health and disease.

Soreq H.

Front Mol Neurosci. 2014 Jun 26;7:55. doi: 10.3389/fnmol.2014.00055. eCollection 2014. No abstract available.

50.

Emerging bioinformatics approaches for analysis of NGS-derived coding and non-coding RNAs in neurodegenerative diseases.

Guffanti A, Simchovitz A, Soreq H.

Front Cell Neurosci. 2014 Mar 27;8:89. doi: 10.3389/fncel.2014.00089. eCollection 2014.

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