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Items: 1 to 50 of 96

1.

The pan-immune system of bacteria: antiviral defence as a community resource.

Bernheim A, Sorek R.

Nat Rev Microbiol. 2019 Nov 6. doi: 10.1038/s41579-019-0278-2. [Epub ahead of print] Review.

PMID:
31695182
2.

A rhlI 5' UTR-Derived sRNA Regulates RhlR-Dependent Quorum Sensing in Pseudomonas aeruginosa.

Thomason MK, Voichek M, Dar D, Addis V, Fitzgerald D, Gottesman S, Sorek R, Greenberg EP.

MBio. 2019 Oct 8;10(5). pii: e02253-19. doi: 10.1128/mBio.02253-19.

3.

Cyclic GMP-AMP signalling protects bacteria against viral infection.

Cohen D, Melamed S, Millman A, Shulman G, Oppenheimer-Shaanan Y, Kacen A, Doron S, Amitai G, Sorek R.

Nature. 2019 Oct;574(7780):691-695. doi: 10.1038/s41586-019-1605-5. Epub 2019 Sep 18.

PMID:
31533127
4.

Widespread Utilization of Peptide Communication in Phages Infecting Soil and Pathogenic Bacteria.

Stokar-Avihail A, Tal N, Erez Z, Lopatina A, Sorek R.

Cell Host Microbe. 2019 May 8;25(5):746-755.e5. doi: 10.1016/j.chom.2019.03.017.

PMID:
31071296
5.

Consent insufficient for data release-Response.

Amann RI, Baichoo S, Blencowe BJ, Bork P, Borodovsky M, Brooksbank C, Chain PSG, Colwell RR, Daffonchio DG, Danchin A, de Lorenzo V, Dorrestein PC, Finn RD, Fraser CM, Gilbert JA, Hallam SJ, Hugenholtz P, Ioannidis JPA, Jansson JK, Kim JF, Klenk HP, Klotz MG, Knight R, Konstantinidis KT, Kyrpides NC, Mason CE, McHardy AC, Meyer F, Ouzounis CA, Patrinos AAN, Podar M, Pollard KS, Ravel J, Muñoz AR, Roberts RJ, Rosselló-Móra R, Sansone SA, Schloss PD, Schriml LM, Setubal JC, Sorek R, Stevens RL, Tiedje JM, Turjanski A, Tyson GW, Ussery DW, Weinstock GM, White O, Whitman WB, Xenarios I.

Science. 2019 May 3;364(6439):446. doi: 10.1126/science.aax7509. No abstract available.

PMID:
31048484
6.

Toward unrestricted use of public genomic data.

Amann RI, Baichoo S, Blencowe BJ, Bork P, Borodovsky M, Brooksbank C, Chain PSG, Colwell RR, Daffonchio DG, Danchin A, de Lorenzo V, Dorrestein PC, Finn RD, Fraser CM, Gilbert JA, Hallam SJ, Hugenholtz P, Ioannidis JPA, Jansson JK, Kim JF, Klenk HP, Klotz MG, Knight R, Konstantinidis KT, Kyrpides NC, Mason CE, McHardy AC, Meyer F, Ouzounis CA, Patrinos AAN, Podar M, Pollard KS, Ravel J, Muñoz AR, Roberts RJ, Rosselló-Móra R, Sansone SA, Schloss PD, Schriml LM, Setubal JC, Sorek R, Stevens RL, Tiedje JM, Turjanski A, Tyson GW, Ussery DW, Weinstock GM, White O, Whitman WB, Xenarios I.

Science. 2019 Jan 25;363(6425):350-352. doi: 10.1126/science.aaw1280. No abstract available.

7.

HflXr, a homolog of a ribosome-splitting factor, mediates antibiotic resistance.

Duval M, Dar D, Carvalho F, Rocha EPC, Sorek R, Cossart P.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):13359-13364. doi: 10.1073/pnas.1810555115. Epub 2018 Dec 13.

8.

Bacterial Noncoding RNAs Excised from within Protein-Coding Transcripts.

Dar D, Sorek R.

MBio. 2018 Sep 25;9(5). pii: e01730-18. doi: 10.1128/mBio.01730-18.

9.

Viruses cooperate to defeat bacteria.

Bernheim A, Sorek R.

Nature. 2018 Jul;559(7715):482-484. doi: 10.1038/d41586-018-05762-1. No abstract available.

PMID:
30038344
10.

The SLE-key test serological signature: new insights into the course of lupus.

Putterman C, Pisetsky DS, Petri M, Caricchio R, Wu AHB, Sanz I, Oates JC, Wallace S, Sorek R, Gerwien R, Safer P, Jakobi-Brook K, Cohen IR.

Rheumatology (Oxford). 2018 Sep 1;57(9):1632-1640. doi: 10.1093/rheumatology/key149.

11.

Successful Brincidofovir Treatment of Metagenomics-detected Adenovirus Infection in a Severely Ill Signal Transducer and Activator of Transcription-1-deficient Patient.

Averbuch D, Safadi R, Dar D, Wolf D, Cherniak M, Sorek R, Amit S.

Pediatr Infect Dis J. 2019 Mar;38(3):297-299. doi: 10.1097/INF.0000000000002090.

PMID:
29742642
12.

High-resolution RNA 3'-ends mapping of bacterial Rho-dependent transcripts.

Dar D, Sorek R.

Nucleic Acids Res. 2018 Jul 27;46(13):6797-6805. doi: 10.1093/nar/gky274.

13.

Extensive reshaping of bacterial operons by programmed mRNA decay.

Dar D, Sorek R.

PLoS Genet. 2018 Apr 18;14(4):e1007354. doi: 10.1371/journal.pgen.1007354. eCollection 2018 Apr.

14.

Contemporary Phage Biology: From Classic Models to New Insights.

Ofir G, Sorek R.

Cell. 2018 Mar 8;172(6):1260-1270. doi: 10.1016/j.cell.2017.10.045. Review.

15.

Systematic discovery of antiphage defense systems in the microbial pangenome.

Doron S, Melamed S, Ofir G, Leavitt A, Lopatina A, Keren M, Amitai G, Sorek R.

Science. 2018 Mar 2;359(6379). pii: eaar4120. doi: 10.1126/science.aar4120. Epub 2018 Jan 25.

16.

Quantitative species-level ecology of reef fish larvae via metabarcoding.

Kimmerling N, Zuqert O, Amitai G, Gurevich T, Armoza-Zvuloni R, Kolesnikov I, Berenshtein I, Melamed S, Gilad S, Benjamin S, Rivlin A, Ohavia M, Paris CB, Holzman R, Kiflawi M, Sorek R.

Nat Ecol Evol. 2018 Feb;2(2):306-316. doi: 10.1038/s41559-017-0413-2. Epub 2017 Dec 18.

PMID:
29255297
17.

DISARM is a widespread bacterial defence system with broad anti-phage activities.

Ofir G, Melamed S, Sberro H, Mukamel Z, Silverman S, Yaakov G, Doron S, Sorek R.

Nat Microbiol. 2018 Jan;3(1):90-98. doi: 10.1038/s41564-017-0051-0. Epub 2017 Oct 30.

18.

Evidence for a cytoplasmic pool of ribosome-free mRNAs encoding inner membrane proteins in Escherichia coli.

Benhalevy D, Biran I, Bochkareva ES, Sorek R, Bibi E.

PLoS One. 2017 Aug 25;12(8):e0183862. doi: 10.1371/journal.pone.0183862. eCollection 2017.

19.

Intracellular signaling in CRISPR-Cas defense.

Amitai G, Sorek R.

Science. 2017 Aug 11;357(6351):550-551. doi: 10.1126/science.aao2210. No abstract available.

PMID:
28798118
20.

Human neonatal thymectomy induces altered B-cell responses and autoreactivity.

van den Broek T, Madi A, Delemarre EM, Schadenberg AWL, Tesselaar K, Borghans JAM, Nierkens S, Redegeld FA, Otten HG, Rossetti M, Albani S, Sorek R, Cohen IR, Jansen NJG, van Wijk F.

Eur J Immunol. 2017 Nov;47(11):1970-1981. doi: 10.1002/eji.201746971. Epub 2017 Sep 6.

21.

Regulation of antibiotic-resistance by non-coding RNAs in bacteria.

Dar D, Sorek R.

Curr Opin Microbiol. 2017 Apr;36:111-117. doi: 10.1016/j.mib.2017.02.005. Epub 2017 Apr 14. Review.

PMID:
28414973
22.

Optimality and sub-optimality in a bacterial growth law.

Towbin BD, Korem Y, Bren A, Doron S, Sorek R, Alon U.

Nat Commun. 2017 Jan 19;8:14123. doi: 10.1038/ncomms14123.

23.

Communication between viruses guides lysis-lysogeny decisions.

Erez Z, Steinberger-Levy I, Shamir M, Doron S, Stokar-Avihail A, Peleg Y, Melamed S, Leavitt A, Savidor A, Albeck S, Amitai G, Sorek R.

Nature. 2017 Jan 26;541(7638):488-493. doi: 10.1038/nature21049. Epub 2017 Jan 18.

24.

Vesicles Spread Susceptibility to Phages.

Ofir G, Sorek R.

Cell. 2017 Jan 12;168(1-2):13-15. doi: 10.1016/j.cell.2016.12.035. Epub 2017 Jan 12.

25.

Widespread formation of alternative 3' UTR isoforms via transcription termination in archaea.

Dar D, Prasse D, Schmitz RA, Sorek R.

Nat Microbiol. 2016 Aug 22;1(10):16143. doi: 10.1038/nmicrobiol.2016.143.

PMID:
27670118
26.

Repeat Size Determination by Two Molecular Rulers in the Type I-E CRISPR Array.

Goren MG, Doron S, Globus R, Amitai G, Sorek R, Qimron U.

Cell Rep. 2016 Sep 13;16(11):2811-2818. doi: 10.1016/j.celrep.2016.08.043.

27.

Computational prediction of regulatory, premature transcription termination in bacteria.

Millman A, Dar D, Shamir M, Sorek R.

Nucleic Acids Res. 2017 Jan 25;45(2):886-893. doi: 10.1093/nar/gkw749. Epub 2016 Aug 29.

28.

Natural selection underlies apparent stress-induced mutagenesis in a bacteriophage infection model.

Yosef I, Edgar R, Levy A, Amitai G, Sorek R, Munitz A, Qimron U.

Nat Microbiol. 2016 Apr 18;1(6):16047. doi: 10.1038/nmicrobiol.2016.47.

29.

CRISPR-Cas: Spacer Diversity Determines the Efficiency of Defense.

Lopatina A, Sorek R.

Curr Biol. 2016 Jul 25;26(14):R683-5. doi: 10.1016/j.cub.2016.05.034.

30.

Comparative transcriptomics across the prokaryotic tree of life.

Cohen O, Doron S, Wurtzel O, Dar D, Edelheit S, Karunker I, Mick E, Sorek R.

Nucleic Acids Res. 2016 Jul 8;44(W1):W46-53. doi: 10.1093/nar/gkw394. Epub 2016 May 6.

31.

Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria.

Dar D, Shamir M, Mellin JR, Koutero M, Stern-Ginossar N, Cossart P, Sorek R.

Science. 2016 Apr 8;352(6282):aad9822. doi: 10.1126/science.aad9822.

32.

CRISPR-Cas adaptation: insights into the mechanism of action.

Amitai G, Sorek R.

Nat Rev Microbiol. 2016 Feb;14(2):67-76. doi: 10.1038/nrmicro.2015.14. Epub 2016 Jan 11. Review.

PMID:
26751509
33.

SLE-key(®) rule-out serologic test for excluding the diagnosis of systemic lupus erythematosus: Developing the ImmunArray iCHIP(®).

Putterman C, Wu A, Reiner-Benaim A, Batty DS Jr, Sanz I, Oates J, Jakobi K, Petri M, Safer P, Gerwien R, Sorek R, Blumenstein Y, Cohen IR.

J Immunol Methods. 2016 Feb;429:1-6. doi: 10.1016/j.jim.2015.12.003. Epub 2015 Dec 8.

34.

Transcriptome dynamics of a broad host-range cyanophage and its hosts.

Doron S, Fedida A, Hernández-Prieto MA, Sabehi G, Karunker I, Stazic D, Feingersch R, Steglich C, Futschik M, Lindell D, Sorek R.

ISME J. 2016 Jun;10(6):1437-55. doi: 10.1038/ismej.2015.210. Epub 2015 Dec 1.

35.

Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples.

Korem T, Zeevi D, Suez J, Weinberger A, Avnit-Sagi T, Pompan-Lotan M, Matot E, Jona G, Harmelin A, Cohen N, Sirota-Madi A, Thaiss CA, Pevsner-Fischer M, Sorek R, Xavier R, Elinav E, Segal E.

Science. 2015 Sep 4;349(6252):1101-1106. doi: 10.1126/science.aac4812. Epub 2015 Jul 30.

36.

CRISPR adaptation biases explain preference for acquisition of foreign DNA.

Levy A, Goren MG, Yosef I, Auster O, Manor M, Amitai G, Edgar R, Qimron U, Sorek R.

Nature. 2015 Apr 23;520(7548):505-510. doi: 10.1038/nature14302. Epub 2015 Apr 13.

37.

BREX is a novel phage resistance system widespread in microbial genomes.

Goldfarb T, Sberro H, Weinstock E, Cohen O, Doron S, Charpak-Amikam Y, Afik S, Ofir G, Sorek R.

EMBO J. 2015 Jan 13;34(2):169-83. doi: 10.15252/embj.201489455. Epub 2014 Dec 1.

38.

Riboswitches. Sequestration of a two-component response regulator by a riboswitch-regulated noncoding RNA.

Mellin JR, Koutero M, Dar D, Nahori MA, Sorek R, Cossart P.

Science. 2014 Aug 22;345(6199):940-3. doi: 10.1126/science.1255083.

39.

Fur is the master regulator of the extraintestinal pathogenic Escherichia coli response to serum.

Huja S, Oren Y, Biran D, Meyer S, Dobrindt U, Bernhard J, Becher D, Hecker M, Sorek R, Ron EZ.

MBio. 2014 Aug 12;5(4). pii: e01460-14. doi: 10.1128/mBio.01460-14.

40.

High-resolution metagenomics.

Mick E, Sorek R.

Nat Biotechnol. 2014 Aug;32(8):750-1. doi: 10.1038/nbt.2962. No abstract available. Erratum in: Nat Biotechnol. 2014 Nov;32(11):1166.

PMID:
25101744
41.

Pregnancy-associated listeriosis: clinical characteristics and geospatial analysis of a 10-year period in Israel.

Elinav H, Hershko-Klement A, Valinsky L, Jaffe J, Wiseman A, Shimon H, Braun E, Paitan Y, Block C, Sorek R, Nir-Paz R; Israeli Listeria Study Group.

Clin Infect Dis. 2014 Oct;59(7):953-61. doi: 10.1093/cid/ciu504. Epub 2014 Jun 27.

PMID:
24973315
42.

Rearrangement of a large novel Pseudomonas aeruginosa gene island in strains isolated from a patient developing ventilator-associated pneumonia.

Singh G, Srinivasan R, Cheng J, Peng Z, Fujimura K, Baek MS, Panzer AR, Tringe SG, Chen F, Sorek R, Weng L, Bristow J, Wiener-Kronish JP, Lynch SV.

J Clin Microbiol. 2014 Jul;52(7):2430-8. doi: 10.1128/JCM.01626-13. Epub 2014 Apr 30.

43.

Correlated occurrence and bypass of frame-shifting insertion-deletions (InDels) to give functional proteins.

Rockah-Shmuel L, Tóth-Petróczy Á, Sela A, Wurtzel O, Sorek R, Tawfik DS.

PLoS Genet. 2013 Oct;9(10):e1003882. doi: 10.1371/journal.pgen.1003882. Epub 2013 Oct 24.

44.

Computational evaluation of cellular metabolic costs successfully predicts genes whose expression is deleterious.

Wagner A, Zarecki R, Reshef L, Gochev C, Sorek R, Gophna U, Ruppin E.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19166-71. doi: 10.1073/pnas.1312361110. Epub 2013 Nov 6.

45.

Differential translation tunes uneven production of operon-encoded proteins.

Quax TE, Wolf YI, Koehorst JJ, Wurtzel O, van der Oost R, Ran W, Blombach F, Makarova KS, Brouns SJ, Forster AC, Wagner EG, Sorek R, Koonin EV, van der Oost J.

Cell Rep. 2013 Sep 12;4(5):938-44. doi: 10.1016/j.celrep.2013.07.049. Epub 2013 Sep 5.

46.

Transcriptome-wide mapping of 5-methylcytidine RNA modifications in bacteria, archaea, and yeast reveals m5C within archaeal mRNAs.

Edelheit S, Schwartz S, Mumbach MR, Wurtzel O, Sorek R.

PLoS Genet. 2013 Jun;9(6):e1003602. doi: 10.1371/journal.pgen.1003602. Epub 2013 Jun 27.

47.

A global transcriptional switch between the attack and growth forms of Bdellovibrio bacteriovorus.

Karunker I, Rotem O, Dori-Bachash M, Jurkevitch E, Sorek R.

PLoS One. 2013 Apr 16;8(4):e61850. doi: 10.1371/journal.pone.0061850. Print 2013.

48.

CRISPR-mediated adaptive immune systems in bacteria and archaea.

Sorek R, Lawrence CM, Wiedenheft B.

Annu Rev Biochem. 2013;82:237-66. doi: 10.1146/annurev-biochem-072911-172315. Epub 2013 Mar 11. Review.

PMID:
23495939
49.

Discovery of functional toxin/antitoxin systems in bacteria by shotgun cloning.

Sberro H, Leavitt A, Kiro R, Koh E, Peleg Y, Qimron U, Sorek R.

Mol Cell. 2013 Apr 11;50(1):136-48. doi: 10.1016/j.molcel.2013.02.002. Epub 2013 Mar 7.

50.

Holding a grudge: persisting anti-phage CRISPR immunity in multiple human gut microbiomes.

Mick E, Stern A, Sorek R.

RNA Biol. 2013 May;10(5):900-6. doi: 10.4161/rna.23929. Epub 2013 Feb 25.

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