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Items: 1 to 50 of 273


Major depressive disorder-associated SIRT1 locus affects the risk for suicide in women after middle age.

Hirata T, Otsuka I, Okazaki S, Mouri K, Horai T, Boku S, Takahashi M, Ueno Y, Sora I, Shirakawa O, Hishimoto A.

Psychiatry Res. 2019 Jun 4;278:141-145. doi: 10.1016/j.psychres.2019.06.002. [Epub ahead of print]


Epigenetic clock analysis of blood samples from Japanese schizophrenia patients.

Okazaki S, Otsuka I, Numata S, Horai T, Mouri K, Boku S, Ohmori T, Sora I, Hishimoto A.

NPJ Schizophr. 2019 Feb 27;5(1):4. doi: 10.1038/s41537-019-0072-1.


Repeated methamphetamine treatment increases spine density in the nucleus accumbens of serotonin transporter knockout mice.

Kasahara Y, Sakakibara Y, Hiratsuka T, Moriya Y, Lesch KP, Hall FS, Uhl GR, Sora I.

Neuropsychopharmacol Rep. 2019 Jun;39(2):130-133. doi: 10.1002/npr2.12049. Epub 2019 Feb 4.


Brain hyperserotonemia causes autism-relevant social deficits in mice.

Tanaka M, Sato A, Kasai S, Hagino Y, Kotajima-Murakami H, Kashii H, Takamatsu Y, Nishito Y, Inagaki M, Mizuguchi M, Hall FS, Uhl GR, Murphy D, Sora I, Ikeda K.

Mol Autism. 2018 Nov 26;9:60. doi: 10.1186/s13229-018-0243-3. eCollection 2018.


Association of CYP2D6 polymorphisms and extrapyramidal symptoms in schizophrenia patients receiving risperidone: a retrospective study.

Ito T, Yamamoto K, Ohsawa F, Otsuka I, Hishimoto A, Sora I, Hirai M, Yano I.

J Pharm Health Care Sci. 2018 Nov 19;4:28. doi: 10.1186/s40780-018-0126-y. eCollection 2018.


Larger Numbers of Glial and Neuronal Cells in the Periaqueductal Gray Matter of μ-Opioid Receptor Knockout Mice.

Sasaki K, Hall FS, Uhl GR, Sora I.

Front Psychiatry. 2018 Sep 19;9:441. doi: 10.3389/fpsyt.2018.00441. eCollection 2018.


Reward-enhancing effect of methylphenidate is abolished in dopamine transporter knockout mice: A model of attention-deficit/hyperactivity disorder.

Ide S, Ikekubo Y, Hua J, Takamatsu Y, Uhl GR, Sora I, Ikeda K.

Neuropsychopharmacol Rep. 2018 Sep;38(3):149-153. doi: 10.1002/npr2.12020. Epub 2018 Jun 29.


Investigation of chromosome Y loss in men with schizophrenia.

Hirata T, Hishimoto A, Otsuka I, Okazaki S, Boku S, Kimura A, Horai T, Sora I.

Neuropsychiatr Dis Treat. 2018 Aug 20;14:2115-2122. doi: 10.2147/NDT.S172886. eCollection 2018.


Mitochondrial DNA copy number of peripheral blood in bipolar disorder: The present study and a meta-analysis.

Yamaki N, Otsuka I, Numata S, Yanagi M, Mouri K, Okazaki S, Boku S, Horai T, Ohmori T, Shirakawa O, Sora I, Hishimoto A.

Psychiatry Res. 2018 Nov;269:115-117. doi: 10.1016/j.psychres.2018.08.014. Epub 2018 Aug 18.


Longer telomeres in elderly schizophrenia are associated with long-term hospitalization in the Japanese population.

Zhang Y, Hishimoto A, Otsuka I, Watanabe Y, Numata S, Yamamori H, Boku S, Horai T, Someya T, Ohmori T, Hashimoto R, Sora I.

J Psychiatr Res. 2018 Aug;103:161-166. doi: 10.1016/j.jpsychires.2018.05.014. Epub 2018 May 21.


Neurocognitive Impairments Are More Severe in the Binge-Eating/Purging Anorexia Nervosa Subtype Than in the Restricting Subtype.

Tamiya H, Ouchi A, Chen R, Miyazawa S, Akimoto Y, Kaneda Y, Sora I.

Front Psychiatry. 2018 Apr 16;9:138. doi: 10.3389/fpsyt.2018.00138. eCollection 2018.


A cross-sectional study exploring useful indicators for low bone mineral density in male alcoholic patients.

Horai T, Hishimoto A, Otsuka I, So T, Mouri K, Shimmyo N, Boku S, Okishio N, Sora I.

Neuropsychiatr Dis Treat. 2018 Feb 28;14:663-669. doi: 10.2147/NDT.S153360. eCollection 2018.


Self-organizing cortex generated from human iPSCs with combination of FGF2 and ambient oxygen.

Eguchi N, Sora I, Muguruma K.

Biochem Biophys Res Commun. 2018 Apr 15;498(4):729-735. doi: 10.1016/j.bbrc.2018.03.049. Epub 2018 Mar 13.


Increased serum levels and promoter polymorphisms of macrophage migration inhibitory factor in schizophrenia.

Okazaki S, Hishimoto A, Otsuka I, Watanabe Y, Numata S, Boku S, Shimmyo N, Kinoshita M, Inoue E, Ohmori T, Someya T, Sora I.

Prog Neuropsychopharmacol Biol Psychiatry. 2018 Apr 20;83:33-41. doi: 10.1016/j.pnpbp.2018.01.001. Epub 2018 Jan 2.


Loss of chromosome Y in blood, but not in brain, of suicide completers.

Kimura A, Hishimoto A, Otsuka I, Okazaki S, Boku S, Horai T, Izumi T, Takahashi M, Ueno Y, Shirakawa O, Sora I.

PLoS One. 2018 Jan 4;13(1):e0190667. doi: 10.1371/journal.pone.0190667. eCollection 2018.


Rare PDCD11 variations are not associated with risk of schizophrenia in Japan.

Hoya S, Watanabe Y, Hishimoto A, Nunokawa A, Kaneko N, Muratake T, Shinmyo N, Otsuka I, Okuda S, Inoue E, Igeta H, Shibuya M, Egawa J, Orime N, Sora I, Someya T.

Psychiatry Clin Neurosci. 2017 Nov;71(11):780-788. doi: 10.1111/pcn.12549. Epub 2017 Jul 31.


Aberrant telomere length and mitochondrial DNA copy number in suicide completers.

Otsuka I, Izumi T, Boku S, Kimura A, Zhang Y, Mouri K, Okazaki S, Shiroiwa K, Takahashi M, Ueno Y, Shirakawa O, Sora I, Hishimoto A.

Sci Rep. 2017 Jun 9;7(1):3176. doi: 10.1038/s41598-017-03599-8.


Association study of MIF promoter polymorphisms with suicide completers in the Japanese population.

Shimmyo N, Hishimoto A, Otsuka I, Okazaki S, Boku S, Mouri K, Horai T, Takahashi M, Ueno Y, Shirakawa O, Sora I.

Neuropsychiatr Dis Treat. 2017 Mar 22;13:899-908. doi: 10.2147/NDT.S130855. eCollection 2017.


Rare FBXO18 variations and risk of schizophrenia: Whole-exome sequencing in two parent-affected offspring trios followed by resequencing and case-control studies.

Hoya S, Watanabe Y, Hishimoto A, Nunokawa A, Inoue E, Igeta H, Otsuka I, Shibuya M, Egawa J, Sora I, Someya T.

Psychiatry Clin Neurosci. 2017 Aug;71(8):562-568. doi: 10.1111/pcn.12526. Epub 2017 May 10.


Optimizing outcomes in clozapine rechallenge following neutropenia using human leukocyte antigen typing: A case report.

Yamaki N, Hishimoto A, Otsuka I, Sasada T, Boku S, Saito T, Yasuda Y, Yamamori H, Ikeda M, Ikeda M, Sora I, Iwata N, Hashimoto R.

Psychiatry Clin Neurosci. 2017 Apr;71(4):289-290. doi: 10.1111/pcn.12505. Epub 2017 Mar 11. No abstract available.


Distinct Roles of Opioid and Dopamine Systems in Lateral Hypothalamic Intracranial Self-Stimulation.

Ide S, Takahashi T, Takamatsu Y, Uhl GR, Niki H, Sora I, Ikeda K.

Int J Neuropsychopharmacol. 2017 May 1;20(5):403-409. doi: 10.1093/ijnp/pyw113.


Neurocognitive profile of euthymic Japanese patients with bipolar disorder.

Ishisaka N, Shimano S, Miura T, Motomura K, Horii M, Imanaga H, Kishimoto J, Kaneda Y, Sora I, Kanba S.

Psychiatry Clin Neurosci. 2017 Jun;71(6):373-382. doi: 10.1111/pcn.12500. Epub 2017 Feb 13.


[Biological review of completed suicide].

Otsuka I, Sora I, Hishimoto A.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2016 Jun;36(3):55-61. Review. Japanese.


The cell cycle-related genes as biomarkers for schizophrenia.

Okazaki S, Boku S, Otsuka I, Mouri K, Aoyama S, Shiroiwa K, Sora I, Fujita A, Shirai Y, Shirakawa O, Kokai M, Hishimoto A.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Oct 3;70:85-91. doi: 10.1016/j.pnpbp.2016.05.005. Epub 2016 May 20.


Slow synaptic transmission mediated by TRPV1 channels in CA3 interneurons of the hippocampus.

Eguchi N, Hishimoto A, Sora I, Mori M.

Neurosci Lett. 2016 Mar 11;616:170-6. doi: 10.1016/j.neulet.2015.12.065. Epub 2016 Feb 1.


Rare truncating variations and risk of schizophrenia: Whole-exome sequencing in three families with affected siblings and a three-stage follow-up study in a Japanese population.

Watanabe Y, Nunokawa A, Shibuya M, Ikeda M, Hishimoto A, Kondo K, Egawa J, Kaneko N, Muratake T, Saito T, Okazaki S, Shimasaki A, Igeta H, Inoue E, Hoya S, Sugai T, Sora I, Iwata N, Someya T.

Psychiatry Res. 2016 Jan 30;235:13-8. doi: 10.1016/j.psychres.2015.12.011. Epub 2015 Dec 11.


A decrease in protein level and a missense polymorphism of KIF17 are associated with schizophrenia.

Ratta-Apha W, Mouri K, Boku S, Ishiguro H, Okazaki S, Otsuka I, Sora I, Arinami T, Shirakawa O, Hishimoto A.

Psychiatry Res. 2015 Dec 15;230(2):424-9. doi: 10.1016/j.psychres.2015.09.031. Epub 2015 Sep 25.


Factors predicting work outcome in Japanese patients with schizophrenia: role of multiple functioning levels.

Sumiyoshi C, Harvey PD, Takaki M, Okahisa Y, Sato T, Sora I, Nuechterlein KH, Subotnik KL, Sumiyoshi T.

Schizophr Res Cogn. 2015 Sep 9;2(3):105-112. doi: 10.1016/j.scog.2015.07.003. eCollection 2015 Sep.


Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies.

Nishizawa D, Kasai S, Hasegawa J, Sato N, Yamada H, Tanioka F, Nagashima M, Katoh R, Satoh Y, Tagami M, Ujike H, Ozaki N, Inada T, Iwata N, Sora I, Iyo M, Yamada M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M, Ohi K, Hashimoto R, Tanisawa K, Arai T, Mori S, Sawabe M, Naka-Mieno M, Yamada Y, Yamada M, Sato N, Muramatsu M, Tanaka M, Irukayama-Tomobe Y, Saito YC, Sakurai T, Hayashida M, Sugimura H, Ikeda K.

Mol Brain. 2015 Aug 20;8:50. doi: 10.1186/s13041-015-0142-x.


Association analysis of the HLA-DRB1*01 and HLA-DRB1*04 with schizophrenia by tag SNP genotyping in the Japanese population.

Ratta-apha W, Boku S, Mouri K, Okazaki S, Otsuka I, Watanabe Y, Nunokawa A, Someya T, Shirakawa O, Sora I, Hishimoto A.

Psychiatry Res. 2015 Sep 30;229(1-2):627-8. doi: 10.1016/j.psychres.2015.07.016. Epub 2015 Jul 10. No abstract available.


Association analysis of the Cadherin13 gene with schizophrenia in the Japanese population.

Otsuka I, Watanabe Y, Hishimoto A, Boku S, Mouri K, Shiroiwa K, Okazaki S, Nunokawa A, Shirakawa O, Someya T, Sora I.

Neuropsychiatr Dis Treat. 2015 Jun 2;11:1381-93. doi: 10.2147/NDT.S84736. eCollection 2015.


The Piccolo Intronic Single Nucleotide Polymorphism rs13438494 Regulates Dopamine and Serotonin Uptake and Shows Associations with Dependence-Like Behavior in Genomic Association Study.

Uno K, Nishizawa D, Seo S, Takayama K, Matsumura S, Sakai N, Ohi K, Nabeshima T, Hashimoto R, Ozaki N, Hasegawa J, Sato N, Tanioka F, Sugimura H, Fukuda KI, Higuchi S, Ujike H, Inada T, Iwata N, Sora I, Iyo M, Kondo N, Won MJ, Naruse N, Uehara-Aoyama K, Itokawa M, Yamada M, Ikeda K, Miyamoto Y, Nitta A.

Curr Mol Med. 2015;15(3):265-74.


Region-specific dendritic spine loss of pyramidal neurons in dopamine transporter knockout mice.

Kasahara Y, Arime Y, Hall FS, Uhl GR, Sora I.

Curr Mol Med. 2015;15(3):237-44.


Improvement of learning and increase in dopamine level in the frontal cortex by methylphenidate in mice lacking dopamine transporter.

Takamatsu Y, Hagino Y, Sato A, Takahashi T, Nagasawa SY, Kubo Y, Mizuguchi M, Uhl GR, Sora I, Ikeda K.

Curr Mol Med. 2015;15(3):245-52.


Methylone-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters.

Piao YS, Hall FS, Moriya Y, Ito M, Ohara A, Kikura-Hanajiri R, Goda Y, Lesch KP, Murphy DL, Uhl GR, Sora I.

Behav Pharmacol. 2015 Jun;26(4):345-52. doi: 10.1097/FBP.0000000000000135.


Serotonin/dopamine interactions in a hyperactive mouse: reduced serotonin receptor 1B activity reverses effects of dopamine transporter knockout.

Hall FS, Sora I, Hen R, Uhl GR.

PLoS One. 2014 Dec 16;9(12):e115009. doi: 10.1371/journal.pone.0115009. eCollection 2014.


Attenuated methamphetamine-induced locomotor sensitization in serotonin transporter knockout mice is restored by serotonin 1B receptor antagonist treatment.

Igari M, Shen HW, Hagino Y, Fukushima S, Kasahara Y, Lesch KP, Murphy DL, Hall FS, Uhl GR, Ikeda K, Yaegashi N, Sora I.

Behav Pharmacol. 2015 Feb;26(1-2):167-79. doi: 10.1097/FBP.0000000000000120.


Sex differences in the effects of adolescent social deprivation on alcohol consumption in μ-opioid receptor knockout mice.

Moriya Y, Kasahara Y, Hall FS, Sakakibara Y, Uhl GR, Tomita H, Sora I.

Psychopharmacology (Berl). 2015 Apr;232(8):1471-82. doi: 10.1007/s00213-014-3784-y. Epub 2014 Nov 4.


Therapeutic concentration of lithium stimulates complement C3 production in dendritic cells and microglia via GSK-3 inhibition.

Yu Z, Ono C, Aiba S, Kikuchi Y, Sora I, Matsuoka H, Tomita H.

Glia. 2015 Feb;63(2):257-70. doi: 10.1002/glia.22749. Epub 2014 Sep 1.


[Analysis of dopamine transporter knockout mice as an animal model of AD/HD].

Kasahara Y, Kubo Y, Sora I.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2013 Nov;33(5-6):185-9. Review. Japanese.


[Genetic vulnerability of methamphetamine dependence].

Moriya Y, Kasahara Y, Sora I.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2013 Aug;33(4):155-60. Review. Japanese.


Specific regions display altered grey matter volume in μ-opioid receptor knockout mice: MRI voxel-based morphometry.

Sasaki K, Sumiyoshi A, Nonaka H, Kasahara Y, Ikeda K, Hall FS, Uhl GR, Watanabe M, Kawashima R, Sora I.

Br J Pharmacol. 2015 Jan;172(2):654-67. doi: 10.1111/bph.12807. Epub 2014 Sep 5.


The involvement of glucocorticoids in psychological stress-induced exacerbations of experimental allergic asthma.

Okuyama K, Dobashi K, Miyasaka T, Yamazaki N, Kikuchi T, Sora I, Takayanagi M, Kita H, Ohno I.

Int Arch Allergy Immunol. 2014;163(4):297-306. doi: 10.1159/000360577. Epub 2014 Apr 26.


Developmental alterations in anxiety and cognitive behavior in serotonin transporter mutant mice.

Sakakibara Y, Kasahara Y, Hall FS, Lesch KP, Murphy DL, Uhl GR, Sora I.

Psychopharmacology (Berl). 2014 Oct;231(21):4119-33. doi: 10.1007/s00213-014-3554-x. Epub 2014 Apr 13.


GABAergic neurons in the ventral tegmental area receive dual GABA/enkephalin-mediated inhibitory inputs from the bed nucleus of the stria terminalis.

Kudo T, Konno K, Uchigashima M, Yanagawa Y, Sora I, Minami M, Watanabe M.

Eur J Neurosci. 2014 Jun;39(11):1796-809. doi: 10.1111/ejn.12503. Epub 2014 Mar 2.


A rare MIR138-2 gene variation is associated with schizophrenia in a Japanese population.

Watanabe Y, Shibuya M, Nunokawa A, Kaneko N, Igeta H, Egawa J, Someya T, Hishimoto A, Mouri K, Sora I.

Psychiatry Res. 2014 Mar 30;215(3):801-2. doi: 10.1016/j.psychres.2013.12.029. Epub 2013 Dec 25. No abstract available.


Association analysis of putative cis-acting polymorphisms of interleukin-19 gene with schizophrenia.

Okazaki S, Watanabe Y, Hishimoto A, Sasada T, Mouri K, Shiroiwa K, Eguchi N, Ratta-Apha W, Otsuka I, Nunokawa A, Kaneko N, Shibuya M, Someya T, Shirakawa O, Sora I.

Prog Neuropsychopharmacol Biol Psychiatry. 2014 Apr 3;50:151-6. doi: 10.1016/j.pnpbp.2013.12.006. Epub 2013 Dec 19.


Haplotype analysis of the DISC1 Ser704Cys variant in Japanese suicide completers.

Ratta-apha W, Hishimoto A, Mouri K, Shiroiwa K, Sasada T, Yoshida M, Okazaki S, Supriyanto I, Asano M, Ueno Y, Shirakawa O, Sora I.

Psychiatry Res. 2014 Jan 30;215(1):249-51. doi: 10.1016/j.psychres.2013.11.007. Epub 2013 Nov 16.


Methamphetamine increases locomotion and dopamine transporter activity in dopamine d5 receptor-deficient mice.

Hayashizaki S, Hirai S, Ito Y, Honda Y, Arime Y, Sora I, Okado H, Kodama T, Takada M.

PLoS One. 2013 Oct 14;8(10):e75975. doi: 10.1371/journal.pone.0075975. eCollection 2013.


A short version of the measurement and treatment research to improve cognition in schizophrenia consensus cognitive battery.

Kaneda Y, Sora I.

Schizophr Res. 2013 Nov;150(2-3):600-1. doi: 10.1016/j.schres.2013.09.002. Epub 2013 Oct 3. No abstract available.


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