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Items: 7

1.

MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo.

Hirai H, Sootome H, Nakatsuru Y, Miyama K, Taguchi S, Tsujioka K, Ueno Y, Hatch H, Majumder PK, Pan BS, Kotani H.

Mol Cancer Ther. 2010 Jul;9(7):1956-67. doi: 10.1158/1535-7163.MCT-09-1012. Epub 2010 Jun 22.

2.

A cell-based screening method for specifically detecting kinase activity.

Suda M, Ishii T, Sootome H, King AJ, Shibahara M, Noro N, Yamashita K, Noumi T.

Anal Bioanal Chem. 2008 Jan;390(1):343-8. Epub 2007 Nov 6.

PMID:
17985120
3.

Dual enzyme-linked immunosorbent assay system for detection of endogenous kinase activities of mitogen- and stress-activated protein kinase-1/2.

Ishii T, Sootome H, Toyoda H, Suda M, Noumi T, Yamashita K.

Assay Drug Dev Technol. 2007 Aug;5(4):523-33.

PMID:
17767420
4.

A selective cellular screening assay for B-Raf and c-Raf kinases.

Ish T, Sootome H, Yagi Y, Yamashita K, Noumi T, Noro N, Ishii T.

J Biomol Screen. 2007 Sep;12(6):818-27. Epub 2007 May 21.

PMID:
17517901
5.

A robust, target-driven, cell-based assay for checkpoint kinase 1 inhibitors.

Ish T, Sootome H, King AJ, Suda M, Noro N, Yamashita K, Noumi T, Ishii T.

J Biomol Screen. 2007 Sep;12(6):809-17. Epub 2007 May 21.

PMID:
17517898
6.

Practical evaluation of universal conditions for four-plex quantitative PCR.

Ishii T, Sootome H, Yamashita K.

Anal Bioanal Chem. 2007 May;388(1):271-8. Epub 2007 Mar 14.

PMID:
17356816
7.

Validation of universal conditions for duplex quantitative reverse transcription polymerase chain reaction assays.

Ishii T, Sootome H, Shan L, Yamashita K.

Anal Biochem. 2007 Mar 15;362(2):201-12. Epub 2006 Dec 29.

PMID:
17257573

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