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Items: 1 to 50 of 79

1.

Efficient ADCC- killing of meningioma by avelumab and a high-affinity natural killer cell line, haNK.

Giles AJ, Hao S, Padget MR, Song H, Zhang W, Lynes J, Sanchez VE, Liu Y, Jung J, Cao X, Fujii R, Jensen RL, Gillespie D, Schlom J, Gilbert MR, Nduom EK, Yang C, Lee JH, Soon-Shiong P, Hodge JW, Park DM.

JCI Insight. 2019 Sep 19. pii: 130688. doi: 10.1172/jci.insight.130688. [Epub ahead of print]

2.

Correction to: Immunotherapy Utilizing the Combination of Natural Killer- and Antibody Dependent Cellular Cytotoxicity (ADCC)-Mediating Agents with Poly (ADP-ribose) polymerase (PARP) Inhibition.

Fenerty KE, Padget M, Wolfson B, Gameiro SR, Su Z, Lee JH, Rabizadeh S, Soon-Shiong P, Hodge JW.

J Immunother Cancer. 2019 Sep 2;7(1):234. doi: 10.1186/s40425-019-0715-9.

3.

Efficient Tumor Clearance and Diversified Immunity through Neoepitope Vaccines and Combinatorial Immunotherapy.

Lee KL, Benz SC, Hicks KC, Nguyen A, Gameiro SR, Palena C, Sanborn JZ, Su Z, Ordentlich P, Rohlin L, Lee JH, Rabizadeh S, Soon-Shiong P, Niazi K, Schlom J, Hamilton DH.

Cancer Immunol Res. 2019 Aug;7(8):1359-1370. doi: 10.1158/2326-6066.CIR-18-0620. Epub 2019 Jul 10.

PMID:
31292145
4.

Toll-like Receptor-4 Activation Boosts the Immunosuppressive Properties of Tumor Cells-derived Exosomes.

Domenis R, Cifù A, Marinò D, Fabris M, Niazi KR, Soon-Shiong P, Curcio F.

Sci Rep. 2019 Jun 11;9(1):8457. doi: 10.1038/s41598-019-44949-y.

5.

An immunogenic NSCLC microenvironment is associated with favorable survival in lung adenocarcinoma.

Givechian KB, Garner C, Benz S, Song B, Rabizadeh S, Soon-Shiong P.

Oncotarget. 2019 Mar 5;10(19):1840-1849. doi: 10.18632/oncotarget.26748. eCollection 2019 Mar 5.

6.

The role of tumor-derived exosomes in cancer immune evasion mediated by toll-like receptor 4 activation.

4° JOINT MEETING OF PATHOLOGY AND LABORATORY MEDICINE SIPMET–SIPMEL - SECOND JOINT MEETING IN COLLABORATION WITH ASIP–AMP–UEMS–WASPALM - 4° SIPMEL NATIONAL CONGRESS - 34° SIPMET NATIONAL CONGRESS - 4° CONGRESS OF PATHOLOGY AND LABORATORY MEDICINE, Domenis R, Cifù R, Marinò D, Fabris M, Niazi KR, Soon-Shiong P, Curcio F.

J Biol Regul Homeost Agents. 2018 Jul-Aug;32(4 Suppl. 1):39. No abstract available.

PMID:
30810016
7.

The multi-functionality of N-809, a novel fusion protein encompassing anti-PD-L1 and the IL-15 superagonist fusion complex.

Jochems C, Tritsch SR, Knudson KM, Gameiro SR, Rumfield CS, Pellom ST, Morillon YM, Newman R, Marcus W, Szeto C, Rabizadeh S, Wong HC, Soon-Shiong P, Schlom J.

Oncoimmunology. 2018 Nov 27;8(2):e1532764. doi: 10.1080/2162402X.2018.1532764. eCollection 2019.

8.

Immunotherapy utilizing the combination of natural killer- and antibody dependent cellular cytotoxicity (ADCC)-mediating agents with poly (ADP-ribose) polymerase (PARP) inhibition.

Fenerty KE, Padget M, Wolfson B, Gameiro SR, Su Z, Lee JH, Rabizadeh S, Soon-Shiong P, Hodge JW.

J Immunother Cancer. 2018 Nov 29;6(1):133. doi: 10.1186/s40425-018-0445-4. Erratum in: J Immunother Cancer. 2019 Sep 2;7(1):234.

9.

Pro inflammatory stimuli enhance the immunosuppressive functions of adipose mesenchymal stem cells-derived exosomes.

Domenis R, Cifù A, Quaglia S, Pistis C, Moretti M, Vicario A, Parodi PC, Fabris M, Niazi KR, Soon-Shiong P, Curcio F.

Sci Rep. 2018 Sep 6;8(1):13325. doi: 10.1038/s41598-018-31707-9.

10.

CAD/POLD2 gene expression is associated with poor overall survival and chemoresistance in bladder urothelial carcinoma.

Givechian KB, Garner C, Garban H, Rabizadeh S, Soon-Shiong P.

Oncotarget. 2018 Jul 3;9(51):29743-29752. doi: 10.18632/oncotarget.25701. eCollection 2018 Jul 3.

11.

Identification of an immune gene expression signature associated with favorable clinical features in Treg-enriched patient tumor samples.

Givechian KB, Wnuk K, Garner C, Benz S, Garban H, Rabizadeh S, Niazi K, Soon-Shiong P.

NPJ Genom Med. 2018 Jun 13;3:14. doi: 10.1038/s41525-018-0054-7. eCollection 2018.

12.

Comprehensive genomic transcriptomic tumor-normal gene panel analysis for enhanced precision in patients with lung cancer.

Rabizadeh S, Garner C, Sanborn JZ, Benz SC, Reddy S, Soon-Shiong P.

Oncotarget. 2018 Apr 10;9(27):19223-19232. doi: 10.18632/oncotarget.24973. eCollection 2018 Apr 10.

13.

Analyses of functions of an anti-PD-L1/TGFβR2 bispecific fusion protein (M7824).

Jochems C, Tritsch SR, Pellom ST, Su Z, Soon-Shiong P, Wong HC, Gulley JL, Schlom J.

Oncotarget. 2017 Sep 8;8(43):75217-75231. doi: 10.18632/oncotarget.20680. eCollection 2017 Sep 26.

14.

New Cancer Immunotherapy Agents in Development: a report from an associated program of the 31stAnnual Meeting of the Society for Immunotherapy of Cancer, 2016.

Adusumilli PS, Cha E, Cornfeld M, Davis T, Diab A, Dubensky TW Jr, Evans E, Grogan JL, Irving BA, Leidner RS, Olwill SA, Soon-Shiong P, Triebel F, Tuck D, Bot A, Dansey RD, Drake CG, Freeman GJ, Ibrahim R, Patel S, Chen DS.

J Immunother Cancer. 2017 Jun 20;5:50. doi: 10.1186/s40425-017-0253-2. eCollection 2017. Review.

15.

Characterization of the Proinflammatory Profile of Synovial Fluid-Derived Exosomes of Patients with Osteoarthritis.

Domenis R, Zanutel R, Caponnetto F, Toffoletto B, Cifù A, Pistis C, Di Benedetto P, Causero A, Pozzi M, Bassini F, Fabris M, Niazi KR, Soon-Shiong P, Curcio F.

Mediators Inflamm. 2017;2017:4814987. doi: 10.1155/2017/4814987. Epub 2017 May 28.

16.

Single-cell sequencing and tumorigenesis: improved understanding of tumor evolution and metastasis.

Ellsworth DL, Blackburn HL, Shriver CD, Rabizadeh S, Soon-Shiong P, Ellsworth RE.

Clin Transl Med. 2017 Dec;6(1):15. doi: 10.1186/s40169-017-0145-6. Epub 2017 Apr 12. Review.

17.

An NK cell line (haNK) expressing high levels of granzyme and engineered to express the high affinity CD16 allele.

Jochems C, Hodge JW, Fantini M, Fujii R, Morillon YM 2nd, Greiner JW, Padget MR, Tritsch SR, Tsang KY, Campbell KS, Klingemann H, Boissel L, Rabizadeh S, Soon-Shiong P, Schlom J.

Oncotarget. 2016 Dec 27;7(52):86359-86373. doi: 10.18632/oncotarget.13411.

18.

Molecular heterogeneity in breast cancer: State of the science and implications for patient care.

Ellsworth RE, Blackburn HL, Shriver CD, Soon-Shiong P, Ellsworth DL.

Semin Cell Dev Biol. 2017 Apr;64:65-72. doi: 10.1016/j.semcdb.2016.08.025. Epub 2016 Aug 26. Review.

19.

Cancer moonshot countdown.

Lowy D, Singer D, DePinho R, Simon GC, Soon-Shiong P.

Nat Biotechnol. 2016 Jun 9;34(6):596-9. doi: 10.1038/nbt.3616. No abstract available.

20.

Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling.

Dave B, Granados-Principal S, Zhu R, Benz S, Rabizadeh S, Soon-Shiong P, Yu KD, Shao Z, Li X, Gilcrease M, Lai Z, Chen Y, Huang TH, Shen H, Liu X, Ferrari M, Zhan M, Wong ST, Kumaraswami M, Mittal V, Chen X, Gross SS, Chang JC.

Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8838-43. doi: 10.1073/pnas.1320769111. Epub 2014 May 29.

21.

Learning subgroup-specific regulatory interactions and regulator independence with PARADIGM.

Sedgewick AJ, Benz SC, Rabizadeh S, Soon-Shiong P, Vaske CJ.

Bioinformatics. 2013 Jul 1;29(13):i62-70. doi: 10.1093/bioinformatics/btt229.

22.

Straight talk with...Patrick Soon-Shiong. Interview by Amber Dance.

Soon-Shiong P.

Nat Med. 2012 Feb 6;18(2):187. doi: 10.1038/nm0212-187. No abstract available.

PMID:
22310674
23.

Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial.

Von Hoff DD, Ramanathan RK, Borad MJ, Laheru DA, Smith LS, Wood TE, Korn RL, Desai N, Trieu V, Iglesias JL, Zhang H, Soon-Shiong P, Shi T, Rajeshkumar NV, Maitra A, Hidalgo M.

J Clin Oncol. 2011 Dec 1;29(34):4548-54. doi: 10.1200/JCO.2011.36.5742. Epub 2011 Oct 3.

24.

Lymphovascular invasion of colorectal cancer is correlated to SPARC expression in the tumor stromal microenvironment.

Yoshimura T, Nagahara M, Kuo C, Turner RR, Soon-Shiong P, Hoon DS.

Epigenetics. 2011 Aug;6(8):1001-11. doi: 10.4161/epi.6.8.16063. Epub 2011 Aug 1.

PMID:
21725199
25.

SPARC Expression Correlates with Tumor Response to Albumin-Bound Paclitaxel in Head and Neck Cancer Patients.

Desai N, Trieu V, Damascelli B, Soon-Shiong P.

Transl Oncol. 2009 May;2(2):59-64.

26.

Improved effectiveness of nanoparticle albumin-bound (nab) paclitaxel versus polysorbate-based docetaxel in multiple xenografts as a function of HER2 and SPARC status.

Desai NP, Trieu V, Hwang LY, Wu R, Soon-Shiong P, Gradishar WJ.

Anticancer Drugs. 2008 Oct;19(9):899-909. doi: 10.1097/CAD.0b013e32830f9046.

PMID:
18766004
27.

Protein nanoparticles as drug carriers in clinical medicine.

Hawkins MJ, Soon-Shiong P, Desai N.

Adv Drug Deliv Rev. 2008 May 22;60(8):876-85. doi: 10.1016/j.addr.2007.08.044. Epub 2008 Feb 7. Review.

PMID:
18423779
28.

Influence of formulation vehicle on metronomic taxane chemotherapy: albumin-bound versus cremophor EL-based paclitaxel.

Ng SS, Sparreboom A, Shaked Y, Lee C, Man S, Desai N, Soon-Shiong P, Figg WD, Kerbel RS.

Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4331-8.

29.

Increased antitumor activity, intratumor paclitaxel concentrations, and endothelial cell transport of cremophor-free, albumin-bound paclitaxel, ABI-007, compared with cremophor-based paclitaxel.

Desai N, Trieu V, Yao Z, Louie L, Ci S, Yang A, Tao C, De T, Beals B, Dykes D, Noker P, Yao R, Labao E, Hawkins M, Soon-Shiong P.

Clin Cancer Res. 2006 Feb 15;12(4):1317-24. Erratum in: Clin Cancer Res. 2006 Jun 15;12(12):3869. Dosage error in article text.

30.

[A tolerability study of A cremophor-free albumin bound nanoparticle paclitaxel intravenously administered in patients with advanced solid tumor].

Teng XY, Guan ZZ, Yao ZW, Liu DG, Zhou NN, Luo HY, Hawkins M, Soon-Shiong P.

Ai Zheng. 2004 Nov;23(11 Suppl):1431-6. Chinese.

PMID:
15566651
31.

Sustained reduction of in-stent neointimal growth with the use of a novel systemic nanoparticle paclitaxel.

Kolodgie FD, John M, Khurana C, Farb A, Wilson PS, Acampado E, Desai N, Soon-Shiong P, Virmani R.

Circulation. 2002 Sep 3;106(10):1195-8.

PMID:
12208792
32.

Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel.

Ibrahim NK, Desai N, Legha S, Soon-Shiong P, Theriault RL, Rivera E, Esmaeli B, Ring SE, Bedikian A, Hortobagyi GN, Ellerhorst JA.

Clin Cancer Res. 2002 May;8(5):1038-44.

33.

Interpenetrating polymer networks of alginate and polyethylene glycol for encapsulation of islets of Langerhans.

Desai NP, Sojomihardjo A, Yao Z, Ron N, Soon-Shiong P.

J Microencapsul. 2000 Nov-Dec;17(6):677-90.

PMID:
11063415
34.

Treatment of type I diabetes using encapsulated islets.

Soon-Shiong P.

Adv Drug Deliv Rev. 1999 Feb 1;35(2-3):259-270.

PMID:
10837701
35.

Molecular mass distribution of sodium alginate by high-performance size-exclusion chromatography.

Ci SX, Huynh TH, Louie LW, Yang A, Beals BJ, Ron N, Tsang WG, Soon-Shiong P, Desai NP.

J Chromatogr A. 1999 Dec 24;864(2):199-210.

PMID:
10669287
36.

Alginate polycation microcapsules. II. Some functional properties.

Thu B, Bruheim P, Espevik T, Smidsrød O, Soon-Shiong P, Skjåk-Braek G.

Biomaterials. 1996 Jun;17(11):1069-79.

PMID:
8718966
37.

Alginate polycation microcapsules. I. Interaction between alginate and polycation.

Thu B, Bruheim P, Espevik T, Smidsrød O, Soon-Shiong P, Skjåk-Braek G.

Biomaterials. 1996 May;17(10):1031-40.

PMID:
8736740
38.
39.

Insulin independence in a type 1 diabetic patient after encapsulated islet transplantation.

Soon-Shiong P, Heintz RE, Merideth N, Yao QX, Yao Z, Zheng T, Murphy M, Moloney MK, Schmehl M, Harris M, et al.

Lancet. 1994 Apr 16;343(8903):950-1.

PMID:
7909011
40.

Intraperitoneal transplantation of microencapsulated canine islet allografts with short-term, low-dose cyclosporine for treatment of pancreatectomy-induced diabetes in dogs.

Wahoff DC, Stephanian E, Gores PF, Soon-Shiong P, Hower C, Lloveras JK, Sutherland DE.

Transplant Proc. 1994 Apr;26(2):804. No abstract available.

PMID:
8171668
41.

Long-term reversal of diabetes by the injection of immunoprotected islets.

Soon-Shiong P, Feldman E, Nelson R, Heintz R, Yao Q, Yao Z, Zheng T, Merideth N, Skjak-Braek G, Espevik T, et al.

Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5843-7.

42.

Human C-peptide response in xenotransplanted diabetic Lewis rats.

Yao Z, Heintz R, Yao Q, Sandford P, Soon-Shiong P.

Transplant Proc. 1992 Dec;24(6):2948-9. No abstract available.

PMID:
1466009
43.

Long-term reversal of diabetes in the large animal model by encapsulated islet transplantation.

Soon-Shiong P, Feldman E, Nelson R, Heintz R, Merideth N, Sandford P, Zheng T, Komtebedde J.

Transplant Proc. 1992 Dec;24(6):2946-7. No abstract available.

PMID:
1466008
44.

Successful reversal of spontaneous diabetes in dogs by intraperitoneal microencapsulated islets.

Soon-Shiong P, Feldman E, Nelson R, Komtebedde J, Smidsrod O, Skjak-Braek G, Espevik T, Heintz R, Lee M.

Transplantation. 1992 Nov;54(5):769-74.

PMID:
1440841
45.

Glucose-insulin kinetics of the extravascular bioartificial pancreas. A study using microencapsulated rat islets.

Soon-Shiong P, Heintz R, Yao Z, Yao Q, Sanford P, Lanza RP, Meredith N.

ASAIO J. 1992 Oct-Dec;38(4):851-4.

PMID:
1450485
46.

Early markers of pancreas transplant rejection.

Zheng T, Lu Z, Merideth N, Lanza RP, Soon-Shiong P.

Am Surg. 1992 Oct;58(10):630-3.

PMID:
1384408
47.

Induction of cytokine production from human monocytes stimulated with alginate.

Otterlei M, Ostgaard K, Skjåk-Braek G, Smidsrød O, Soon-Shiong P, Espevik T.

J Immunother (1991). 1991 Aug;10(4):286-91.

PMID:
1931864
48.
49.

An immunologic basis for the fibrotic reaction to implanted microcapsules.

Soon-Shiong P, Otterlie M, Skjak-Braek G, Smidsrod O, Heintz R, Lanza RP, Espevik T.

Transplant Proc. 1991 Feb;23(1 Pt 1):758-9. No abstract available.

PMID:
1990681
50.

Prolonged pancreas preservation using a simplified UW solution containing polyethylene glycol.

Zheng TL, Lanza RP, Soon-Shiong P.

Transplantation. 1991 Jan;51(1):63-6.

PMID:
1987707

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