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Items: 6


JAK1/2 pathway inhibition suppresses M2 polarization and overcomes resistance of myeloma to lenalidomide by reducing TRIB1, MUC1, CD44, CXCL12, and CXCR4 expression.

Chen H, Li M, Sanchez E, Soof CM, Bujarski S, Ng N, Cao J, Hekmati T, Zahab B, Nosrati JD, Wen M, Wang CS, Tang G, Xu N, Spektor TM, Berenson JR.

Br J Haematol. 2019 Aug 18. doi: 10.1111/bjh.16158. [Epub ahead of print]


Serum B-cell maturation antigen (BCMA) reduces binding of anti-BCMA antibody to multiple myeloma cells.

Chen H, Li M, Xu N, Ng N, Sanchez E, Soof CM, Patil S, Udd K, Bujarski S, Cao J, Hekmati T, Ghermezi M, Zhou M, Wang EY, Tanenbaum EJ, Zahab B, Schlossberg R, Yashar MA, Wang CS, Tang GY, Spektor TM, Berenson JR.

Leuk Res. 2019 Jun;81:62-66. doi: 10.1016/j.leukres.2019.04.008. Epub 2019 Apr 18.


The anti-myeloma effects of the selective JAK1 inhibitor (INCB052793) alone and in combination in vitro and in vivo.

Sanchez E, Li M, Patil S, Soof CM, Nosrati JD, Schlossberg RE, Vidisheva A, Tanenbaum EJ, Hekmati T, Zahab B, Wang C, Tang G, Chen H, Berenson JR.

Ann Hematol. 2019 Mar;98(3):691-703. doi: 10.1007/s00277-019-03595-0. Epub 2019 Jan 11.


The clinical significance of B-cell maturation antigen as a therapeutic target and biomarker.

Sanchez E, Tanenbaum EJ, Patil S, Li M, Soof CM, Vidisheva A, Waterman GN, Hekmati T, Tang G, Wang CS, Chen H, Berenson J.

Expert Rev Mol Diagn. 2018 Apr;18(4):319-329. doi: 10.1080/14737159.2018.1448269. Epub 2018 Mar 7. Review.


The Role of B-Cell Maturation Antigen in the Biology and Management of, and as a Potential Therapeutic Target in, Multiple Myeloma.

Sanchez E, Smith EJ, Yashar MA, Patil S, Li M, Porter AL, Tanenbaum EJ, Schlossberg RE, Soof CM, Hekmati T, Tang G, Wang CS, Chen H, Berenson JR.

Target Oncol. 2018 Feb;13(1):39-47. doi: 10.1007/s11523-017-0538-x. Review.


Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects.

Chen H, Li M, Sanchez E, Wang CS, Lee T, Soof CM, Casas CE, Cao J, Xie C, Udd KA, DeCorso K, Tang GY, Spektor TM, Berenson JR.

Mol Cancer Res. 2017 May;15(5):598-609. doi: 10.1158/1541-7786.MCR-16-0293. Epub 2017 Jan 25.

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