Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 101


Acute iodine deficiency induces a transient VEGF dependent microvascular response in mammary glands involving HIF-1, ROS and mTOR.

Vanderstraeten J, Derradji H, Sonveaux P, Colin I, Many MC, Gérard AC.

Am J Physiol Cell Physiol. 2018 Jul 18. doi: 10.1152/ajpcell.00095.2017. [Epub ahead of print]


Long-term antigen exposure irreversibly modifies metabolic requirements for T cell function.

Bettonville M, d'Aria S, Weatherly K, Porporato PE, Zhang J, Bousbata S, Sonveaux P, Braun MY.

Elife. 2018 Jun 18;7. pii: e30938. doi: 10.7554/eLife.30938.


Mitochondrial Alterations (Inhibition of Mitochondrial Protein Expression, Oxidative Metabolism, and Ultrastructure) Induced by Linezolid and Tedizolid at Clinically Relevant Concentrations in Cultured Human HL-60 Promyelocytes and THP-1 Monocytes.

Milosevic TV, Payen VL, Sonveaux P, Muccioli GG, Tulkens PM, Van Bambeke F.

Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e01599-17. doi: 10.1128/AAC.01599-17. Print 2018 Mar.


(+)-Catechin in a 1:2 Complex with Lysine Inhibits Cancer Cell Migration and Metastatic Take in Mice.

Payen VL, Porporato PE, Danhier P, Vazeille T, Blackman MCNM, May BH, Niebes P, Sonveaux P.

Front Pharmacol. 2017 Dec 4;8:869. doi: 10.3389/fphar.2017.00869. eCollection 2017.


Lactate stimulates CA IX expression in normoxic cancer cells.

Panisova E, Kery M, Sedlakova O, Brisson L, Debreova M, Sboarina M, Sonveaux P, Pastorekova S, Svastova E.

Oncotarget. 2017 Sep 12;8(44):77819-77835. doi: 10.18632/oncotarget.20836. eCollection 2017 Sep 29.


Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology.

Contino S, Porporato PE, Bird M, Marinangeli C, Opsomer R, Sonveaux P, Bontemps F, Dewachter I, Octave JN, Bertrand L, Stanga S, Kienlen-Campard P.

Front Physiol. 2017 Oct 12;8:796. doi: 10.3389/fphys.2017.00796. eCollection 2017.


Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses.

Baselet B, Azimzadeh O, Erbeldinger N, Bakshi MV, Dettmering T, Janssen A, Ktitareva S, Lowe DJ, Michaux A, Quintens R, Raj K, Durante M, Fournier C, Benotmane MA, Baatout S, Sonveaux P, Tapio S, Aerts A.

Front Pharmacol. 2017 Sep 22;8:570. doi: 10.3389/fphar.2017.00570. eCollection 2017.


Ffar2 expression regulates leukaemic cell growth in vivo.

Bindels LB, Porporato PE, Ducastel S, Sboarina M, Neyrinck AM, Dewulf EM, Feron O, Lestavel S, Cani PD, Staels B, Sonveaux P, Delzenne NM.

Br J Cancer. 2017 Oct 24;117(9):1336-1340. doi: 10.1038/bjc.2017.307. Epub 2017 Sep 5.


MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases.

Lemma S, Di Pompo G, Porporato PE, Sboarina M, Russell S, Gillies RJ, Baldini N, Sonveaux P, Avnet S.

Biochim Biophys Acta. 2017 Dec;1863(12):3254-3264. doi: 10.1016/j.bbadis.2017.08.030. Epub 2017 Sep 1.


Monocarboxylate Transporter MCT1 Promotes Tumor Metastasis Independently of Its Activity as a Lactate Transporter.

Payen VL, Hsu MY, Rädecke KS, Wyart E, Vazeille T, Bouzin C, Porporato PE, Sonveaux P.

Cancer Res. 2017 Oct 15;77(20):5591-5601. doi: 10.1158/0008-5472.CAN-17-0764. Epub 2017 Aug 21.


Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer.

Baldini N, De Milito A, Feron O, Gillies RJ, Michiels C, Otto AM, Pastoreková S, Pedersen SF, Porporato PE, Sonveaux P, Supuran CT, Avnet S.

Front Pharmacol. 2017 Jul 4;8:411. doi: 10.3389/fphar.2017.00411. eCollection 2017.


Mitochondria in cancer.

Gasparre G, Rossignol R, Sonveaux P.

Biochim Biophys Acta. 2017 Aug;1858(8):553-555. doi: 10.1016/j.bbabio.2017.05.004. No abstract available.


Functional Gene Analysis Reveals Cell Cycle Changes and Inflammation in Endothelial Cells Irradiated with a Single X-ray Dose.

Baselet B, Belmans N, Coninx E, Lowe D, Janssen A, Michaux A, Tabury K, Raj K, Quintens R, Benotmane MA, Baatout S, Sonveaux P, Aerts A.

Front Pharmacol. 2017 Apr 25;8:213. doi: 10.3389/fphar.2017.00213. eCollection 2017.


Contribution of macrophages in the contrast loss in iron oxide-based MRI cancer cell tracking studies.

Danhier P, Deumer G, Joudiou N, Bouzin C, Levêque P, Haufroid V, Jordan BF, Feron O, Sonveaux P, Gallez B.

Oncotarget. 2017 Jun 13;8(24):38876-38885. doi: 10.18632/oncotarget.17103.


ROS and radiotherapy: more we care.

Sonveaux P.

Oncotarget. 2017 May 30;8(22):35482-35483. doi: 10.18632/oncotarget.16613. No abstract available.


Cancer metabolism in space and time: Beyond the Warburg effect.

Danhier P, Bański P, Payen VL, Grasso D, Ippolito L, Sonveaux P, Porporato PE.

Biochim Biophys Acta. 2017 Aug;1858(8):556-572. doi: 10.1016/j.bbabio.2017.02.001. Epub 2017 Feb 4. Review.


Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors.

Van Hée VF, Labar D, Dehon G, Grasso D, Grégoire V, Muccioli GG, Frédérick R, Sonveaux P.

Oncotarget. 2017 Apr 11;8(15):24415-24428. doi: 10.18632/oncotarget.14705.


Multimodality Imaging Identifies Distinct Metabolic Profiles In Vitro and In Vivo.

Neveu MA, De Preter G, Marchand V, Bol A, Brender JR, Saito K, Kishimoto S, Porporato PE, Sonveaux P, Grégoire V, Feron O, Jordan BF, Krishna MC, Gallez B.

Neoplasia. 2016 Dec;18(12):742-752. doi: 10.1016/j.neo.2016.10.010. Epub 2016 Nov 24.


Cancer heterogeneity is not compatible with one unique cancer cell metabolic map.

Strickaert A, Saiselet M, Dom G, De Deken X, Dumont JE, Feron O, Sonveaux P, Maenhaut C.

Oncogene. 2017 May 11;36(19):2637-2642. doi: 10.1038/onc.2016.411. Epub 2016 Oct 31. Review.


Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism.

Cacace A, Sboarina M, Vazeille T, Sonveaux P.

Oncogene. 2017 Apr;36(15):2074-2084. doi: 10.1038/onc.2016.364. Epub 2016 Oct 17.


Lactate Dehydrogenase B Controls Lysosome Activity and Autophagy in Cancer.

Brisson L, Bański P, Sboarina M, Dethier C, Danhier P, Fontenille MJ, Van Hée VF, Vazeille T, Tardy M, Falces J, Bouzin C, Porporato PE, Frédérick R, Michiels C, Copetti T, Sonveaux P.

Cancer Cell. 2016 Sep 12;30(3):418-431. doi: 10.1016/j.ccell.2016.08.005.


Energy metabolism in osteoclast formation and activity.

Lemma S, Sboarina M, Porporato PE, Zini N, Sonveaux P, Di Pompo G, Baldini N, Avnet S.

Int J Biochem Cell Biol. 2016 Oct;79:168-180. doi: 10.1016/j.biocel.2016.08.034. Epub 2016 Aug 30.


Paracrine nitric oxide induces expression of cardiac sarcomeric proteins in adult progenitor cells through soluble guanylyl cyclase/cyclic-guanosine monophosphate and Wnt/β-catenin inhibition.

De Pauw A, Massion P, Sekkali B, Andre E, Dubroca C, Kmecova J, Bouzin C, Friart A, Sibille C, Gilon P, De Mulder D, Esfahani H, Strapart A, Martherus R, Payen V, Sonveaux P, Brouckaert P, Janssens S, Balligand JL.

Cardiovasc Res. 2016 Oct;112(1):478-90. doi: 10.1093/cvr/cvw196. Epub 2016 Aug 12.


Paving the way for therapeutic prevention of tumor metastasis with agents targeting mitochondrial superoxide.

Porporato PE, Sonveaux P.

Mol Cell Oncol. 2014 Oct 29;2(3):e968043. doi: 10.4161/23723548.2014.968043. eCollection 2015 Jul-Sep.


Channels and transporters in cell metabolism.

Sonveaux P, Maechler P, Martinou JC.

Biochim Biophys Acta. 2016 Oct;1863(10):2359-61. doi: 10.1016/j.bbamcr.2016.06.001. Epub 2016 Jun 3. No abstract available.


Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells.

Chano T, Avnet S, Kusuzaki K, Bonuccelli G, Sonveaux P, Rotili D, Mai A, Baldini N.

Am J Cancer Res. 2016 Mar 15;6(4):859-75. eCollection 2016.


Involvement of mTOR and Regulation by AMPK in Early Iodine Deficiency-Induced Thyroid Microvascular Activation.

Craps J, Joris V, De Jongh B, Sonveaux P, Horman S, Lengelé B, Bertrand L, Many MC, Colin IM, Gérard AC.

Endocrinology. 2016 Jun;157(6):2545-59. doi: 10.1210/en.2015-1911. Epub 2016 Apr 1.


Monocarboxylate transporters in the brain and in cancer.

Pérez-Escuredo J, Van Hée VF, Sboarina M, Falces J, Payen VL, Pellerin L, Sonveaux P.

Biochim Biophys Acta. 2016 Oct;1863(10):2481-97. doi: 10.1016/j.bbamcr.2016.03.013. Epub 2016 Mar 16. Review.


Iodine deficiency induces a VEGF-dependent microvascular response in salivary glands and in the stomach.

Vanderstraeten J, Derradji H, Craps J, Sonveaux P, Colin IM, Many MC, Gérard AC.

Histol Histopathol. 2016 Aug;31(8):897-909. doi: 10.14670/HH-11-727. Epub 2016 Feb 3.


Direct Evidence of the Link Between Energetic Metabolism and Proliferation Capacity of Cancer Cells In Vitro.

De Preter G, Danhier P, Porporato PE, Payen VL, Jordan BF, Sonveaux P, Gallez B.

Adv Exp Med Biol. 2016;876:209-214. doi: 10.1007/978-1-4939-3023-4_26.


A Fast Hydrogen Sulfide-Releasing Donor Increases the Tumor Response to Radiotherapy.

De Preter G, Deriemaeker C, Danhier P, Brisson L, Cao Pham TT, Grégoire V, Jordan BF, Sonveaux P, Gallez B.

Mol Cancer Ther. 2016 Jan;15(1):154-61. doi: 10.1158/1535-7163.MCT-15-0691-T. Epub 2015 Dec 18.


Application of Electron Paramagnetic Resonance (EPR) Oximetry to Monitor Oxygen in Wounds in Diabetic Models.

Desmet CM, Lafosse A, Vériter S, Porporato PE, Sonveaux P, Dufrane D, Levêque P, Gallez B.

PLoS One. 2015 Dec 14;10(12):e0144914. doi: 10.1371/journal.pone.0144914. eCollection 2015.


Metabolic changes associated with tumor metastasis, part 2: Mitochondria, lipid and amino acid metabolism.

Porporato PE, Payen VL, Baselet B, Sonveaux P.

Cell Mol Life Sci. 2016 Apr;73(7):1349-63. doi: 10.1007/s00018-015-2100-2. Epub 2015 Dec 8. Review.


Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.

Pérez-Escuredo J, Dadhich RK, Dhup S, Cacace A, Van Hée VF, De Saedeleer CJ, Sboarina M, Rodriguez F, Fontenille MJ, Brisson L, Porporato PE, Sonveaux P.

Cell Cycle. 2016;15(1):72-83. doi: 10.1080/15384101.2015.1120930.


Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway.

Payen VL, Porporato PE, Baselet B, Sonveaux P.

Cell Mol Life Sci. 2016 Apr;73(7):1333-48. doi: 10.1007/s00018-015-2098-5. Epub 2015 Dec 1. Review.


Non-invasive in vivo imaging of early metabolic tumor response to therapies targeting choline metabolism.

Mignion L, Danhier P, Magat J, Porporato PE, Masquelier J, Gregoire V, Muccioli GG, Sonveaux P, Gallez B, Jordan BF.

Int J Cancer. 2016 Apr 15;138(8):2043-9. doi: 10.1002/ijc.29932. Epub 2015 Dec 9.


Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation.

De Preter G, Neveu MA, Danhier P, Brisson L, Payen VL, Porporato PE, Jordan BF, Sonveaux P, Gallez B.

Oncotarget. 2016 Jan 19;7(3):2910-20. doi: 10.18632/oncotarget.6272.


Lactate does not activate NF-κB in oxidative tumor cells.

Van Hée VF, Pérez-Escuredo J, Cacace A, Copetti T, Sonveaux P.

Front Pharmacol. 2015 Oct 13;6:228. doi: 10.3389/fphar.2015.00228. eCollection 2015.


Combined effects of PLGA and vascular endothelial growth factor promote the healing of non-diabetic and diabetic wounds.

Chereddy KK, Lopes A, Koussoroplis S, Payen V, Moia C, Zhu H, Sonveaux P, Carmeliet P, des Rieux A, Vandermeulen G, Préat V.

Nanomedicine. 2015 Nov;11(8):1975-84. doi: 10.1016/j.nano.2015.07.006. Epub 2015 Jul 31.


Common responses of tumors and wounds to hypoxia.

Payen VL, Brisson L, Dewhirst MW, Sonveaux P.

Cancer J. 2015 Mar-Apr;21(2):75-87. doi: 10.1097/PPO.0000000000000098. Review.


In vivo visualization and ex vivo quantification of murine breast cancer cells in the mouse brain using MRI cell tracking and electron paramagnetic resonance.

Danhier P, Magat J, Levêque P, De Preter G, Porporato PE, Bouzin C, Jordan BF, Demeur G, Haufroid V, Feron O, Sonveaux P, Gallez B.

NMR Biomed. 2015 Mar;28(3):367-75. doi: 10.1002/nbm.3259. Epub 2015 Jan 22.


Paclitaxel-loaded micelles enhance transvascular permeability and retention of nanomedicines in tumors.

Danhier F, Danhier P, De Saedeleer CJ, Fruytier AC, Schleich N, des Rieux A, Sonveaux P, Gallez B, Préat V.

Int J Pharm. 2015 Feb 20;479(2):399-407. doi: 10.1016/j.ijpharm.2015.01.009. Epub 2015 Jan 8.


Proton channels and exchangers in cancer.

Spugnini EP, Sonveaux P, Stock C, Perez-Sayans M, De Milito A, Avnet S, Garcìa AG, Harguindey S, Fais S.

Biochim Biophys Acta. 2015 Oct;1848(10 Pt B):2715-26. doi: 10.1016/j.bbamem.2014.10.015. Epub 2014 Oct 20. Review.


Involvement of nitric oxide in iodine deficiency-induced microvascular remodeling in the thyroid gland: role of nitric oxide synthase 3 and ryanodine receptors.

Craps J, Wilvers C, Joris V, De Jongh B, Vanderstraeten J, Lobysheva I, Balligand JL, Sonveaux P, Gilon P, Many MC, Gérard AC, Colin IM.

Endocrinology. 2015 Feb;156(2):707-20. doi: 10.1210/en.2014-1729. Epub 2014 Nov 18.


PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing.

Chereddy KK, Her CH, Comune M, Moia C, Lopes A, Porporato PE, Vanacker J, Lam MC, Steinstraesser L, Sonveaux P, Zhu H, Ferreira LS, Vandermeulen G, Préat V.

J Control Release. 2014 Nov 28;194:138-47. doi: 10.1016/j.jconrel.2014.08.016. Epub 2014 Aug 27.


A mitochondrial switch promotes tumor metastasis.

Porporato PE, Payen VL, Pérez-Escuredo J, De Saedeleer CJ, Danhier P, Copetti T, Dhup S, Tardy M, Vazeille T, Bouzin C, Feron O, Michiels C, Gallez B, Sonveaux P.

Cell Rep. 2014 Aug 7;8(3):754-66. doi: 10.1016/j.celrep.2014.06.043. Epub 2014 Jul 24.


Reprogramming of tumor metabolism by targeting mitochondria improves tumor response to irradiation.

Bol V, Bol A, Bouzin C, Labar D, Lee JA, Janssens G, Porporato PE, Sonveaux P, Feron O, Grégoire V.

Acta Oncol. 2015 Feb;54(2):266-74. doi: 10.3109/0284186X.2014.932006. Epub 2014 Jul 9.


Antitumor activity of 7-aminocarboxycoumarin derivatives, a new class of potent inhibitors of lactate influx but not efflux.

Draoui N, Schicke O, Seront E, Bouzin C, Sonveaux P, Riant O, Feron O.

Mol Cancer Ther. 2014 Jun;13(6):1410-8. doi: 10.1158/1535-7163.MCT-13-0653. Epub 2014 Mar 26.


Multimodal cell tracking of a spontaneous metastasis model: comparison between MRI, electron paramagnetic resonance and bioluminescence.

Danhier P, De Preter G, Magat J, Godechal Q, Porporato PE, Jordan BF, Feron O, Sonveaux P, Gallez B.

Contrast Media Mol Imaging. 2014 Mar-Apr;9(2):143-53. doi: 10.1002/cmmi.1553.


Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide promotes wound healing.

Steinstraesser L, Lam MC, Jacobsen F, Porporato PE, Chereddy KK, Becerikli M, Stricker I, Hancock RE, Lehnhardt M, Sonveaux P, Préat V, Vandermeulen G.

Mol Ther. 2014 Apr;22(4):734-42. doi: 10.1038/mt.2013.258. Epub 2013 Dec 5.

Supplemental Content

Loading ...
Support Center