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Items: 1 to 50 of 162


mTORC1-Rps15 Axis Contributes to the Mechanisms Underlying Global Translation Reduction During Senescence of Mouse Embryonic Fibroblasts.

Wu S, Xu S, Li R, Li K, Zhong X, Li Y, Zhou Z, Liu Y, Feng R, Zheng J, Songyang Z, Liu F.

Front Cell Dev Biol. 2019 Dec 11;7:337. doi: 10.3389/fcell.2019.00337. eCollection 2019.


Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway.

Xu M, Qin J, Wang L, Lee HJ, Kao CY, Liu D, Songyang Z, Chen J, Tsai MJ, Tsai SY.

Sci Adv. 2019 Oct 9;5(10):eaax6366. doi: 10.1126/sciadv.aax6366. eCollection 2019 Oct.


The role of telomere-binding modulators in pluripotent stem cells.

Li F, Ge Y, Liu D, Songyang Z.

Protein Cell. 2020 Jan;11(1):60-70. doi: 10.1007/s13238-019-0651-y. Epub 2019 Jul 27. Review.


Pan-cancer analysis identifies telomerase-associated signatures and cancer subtypes.

Luo Z, Wang W, Li F, Songyang Z, Feng X, Xin C, Dai Z, Xiong Y.

Mol Cancer. 2019 Jun 10;18(1):106. doi: 10.1186/s12943-019-1035-x.


The long non-coding RNA Snhg3 is essential for mouse embryonic stem cell self-renewal and pluripotency.

Lu W, Yu J, Shi F, Zhang J, Huang R, Yin S, Songyang Z, Huang J.

Stem Cell Res Ther. 2019 May 31;10(1):157. doi: 10.1186/s13287-019-1270-5.


Interaction Between Sympk and Oct4 Promotes Mouse Embryonic Stem Cell Proliferation.

Yu J, Lu W, Ge T, Huang R, Chen B, Ye M, Bai Y, Shi G, Songyang Z, Ma W, Huang J.

Stem Cells. 2019 Jun;37(6):743-753. doi: 10.1002/stem.2992. Epub 2019 Mar 9.


Genome-wide profiling of adenine base editor specificity by EndoV-seq.

Liang P, Xie X, Zhi S, Sun H, Zhang X, Chen Y, Chen Y, Xiong Y, Ma W, Liu D, Huang J, Songyang Z.

Nat Commun. 2019 Jan 8;10(1):67. doi: 10.1038/s41467-018-07988-z.


Phosphorylation of PLIN3 by AMPK promotes dispersion of lipid droplets during starvation.

Zhu J, Xu M, Liu Y, Zhuang L, Ying K, Liu F, Liu D, Ma W, Songyang Z.

Protein Cell. 2019 May;10(5):382-387. doi: 10.1007/s13238-018-0593-9. No abstract available.


TOE1 acts as a 3' exonuclease for telomerase RNA and regulates telomere maintenance.

Deng T, Huang Y, Weng K, Lin S, Li Y, Shi G, Chen Y, Huang J, Liu D, Ma W, Songyang Z.

Nucleic Acids Res. 2019 Jan 10;47(1):391-405. doi: 10.1093/nar/gky1019.


Effective and precise adenine base editing in mouse zygotes.

Liang P, Sun H, Zhang X, Xie X, Zhang J, Bai Y, Ouyang X, Zhi S, Xiong Y, Ma W, Liu D, Huang J, Songyang Z.

Protein Cell. 2018 Sep;9(9):808-813. doi: 10.1007/s13238-018-0566-z. No abstract available.


Homozygous OB-fold variants in telomere protein TPP1 are associated with dyskeratosis congenita-like phenotypes.

Tummala H, Collopy LC, Walne AJ, Ellison A, Cardoso S, Aksu T, Yarali N, Aslan D, Fikret Akata R, Teo J, Songyang Z, Pontikos N, Fitzgibbon J, Tomita K, Vulliamy T, Dokal I.

Blood. 2018 Sep 20;132(12):1349-1353. doi: 10.1182/blood-2018-03-837799. Epub 2018 Jul 31. No abstract available.


Author Correction: HuR regulates telomerase activity through TERC methylation.

Tang H, Wang H, Cheng X, Fan X, Yang F, Zhang M, Chen Y, Tian Y, Liu C, Shao D, Jiang B, Dou Y, Cong Y, Xing J, Zhang X, Yi X, Songyang Z, Ma W, Zhao Y, Wang X, Ma J, Gorospe M, Ju Z, Wang W.

Nat Commun. 2018 Jul 10;9(1):2721. doi: 10.1038/s41467-018-05213-5.


Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A.

Wang M, Zhang S, Zheng G, Huang J, Songyang Z, Zhao X, Lin X.

Immunity. 2018 Jul 17;49(1):66-79.e5. doi: 10.1016/j.immuni.2018.05.012. Epub 2018 Jul 3.


HuR regulates telomerase activity through TERC methylation.

Tang H, Wang H, Cheng X, Fan X, Yang F, Zhang M, Chen Y, Tian Y, Liu C, Shao D, Jiang B, Dou Y, Cong Y, Xing J, Zhang X, Yi X, Songyang Z, Ma W, Zhao Y, Wang X, Ma J, Gorospe M, Ju Z, Wang W.

Nat Commun. 2018 Jun 7;9(1):2213. doi: 10.1038/s41467-018-04617-7. Erratum in: Nat Commun. 2018 Jul 10;9(1):2721.


The BUB3-BUB1 Complex Promotes Telomere DNA Replication.

Li F, Kim H, Ji Z, Zhang T, Chen B, Ge Y, Hu Y, Feng X, Han X, Xu H, Zhang Y, Yu H, Liu D, Ma W, Songyang Z.

Mol Cell. 2018 May 3;70(3):395-407.e4. doi: 10.1016/j.molcel.2018.03.032.


Cationic Polymer-Mediated CRISPR/Cas9 Plasmid Delivery for Genome Editing.

Zhang Z, Wan T, Chen Y, Chen Y, Sun H, Cao T, Songyang Z, Tang G, Wu C, Ping Y, Xu FJ, Huang J.

Macromol Rapid Commun. 2019 Mar;40(5):e1800068. doi: 10.1002/marc.201800068. Epub 2018 Apr 30.


Analysis of hpf1 expression and function in early embryonic development of zebrafish.

Zhang Z, Sun H, Chen Y, Cao T, Songyang Z, Huang J, Huang Y.

Dev Genes Evol. 2018 Mar;228(2):141-147. doi: 10.1007/s00427-018-0608-9. Epub 2018 Mar 17.


Shwachman-Diamond Syndrome Protein SBDS Maintains Human Telomeres by Regulating Telomerase Recruitment.

Liu Y, Liu F, Cao Y, Xu H, Wu Y, Wu S, Liu D, Zhao Y, Songyang Z, Ma W.

Cell Rep. 2018 Feb 13;22(7):1849-1860. doi: 10.1016/j.celrep.2018.01.057.


Oncogenic Kinase-Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem-like Cells.

Zhou Z, Li M, Zhang L, Zhao H, Şahin Ö, Chen J, Zhao JJ, Songyang Z, Yu D.

Cancer Res. 2018 May 1;78(9):2248-2261. doi: 10.1158/0008-5472.CAN-17-2726. Epub 2018 Feb 12.


Testis-specific Lypd9 is dispensable for spermatogenesis in mouse.

Feng J, Liang P, Chen Y, Zhang X, Songyang Z, Zheng H, Cao S, Huang J.

Mol Reprod Dev. 2018 Feb;85(2):87-89. doi: 10.1002/mrd.22942. Epub 2018 Jan 9. No abstract available.


Single-walled carbon nanotube: One specific inhibitor of cancer stem cells in osteosarcoma upon downregulation of the TGFβ1 signaling.

Miao Y, Zhang H, Pan Y, Ren J, Ye M, Xia F, Huang R, Lin Z, Jiang S, Zhang Y, Songyang Z, Zhang Y.

Biomaterials. 2017 Dec;149:29-40. doi: 10.1016/j.biomaterials.2017.09.032. Epub 2017 Sep 26.


pgRNAFinder: a web-based tool to design distance independent paired-gRNA.

Xiong Y, Xie X, Wang Y, Ma W, Liang P, Songyang Z, Dai Z.

Bioinformatics. 2017 Nov 15;33(22):3642-3644. doi: 10.1093/bioinformatics/btx472.


Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells.

Kim H, Li F, He Q, Deng T, Xu J, Jin F, Coarfa C, Putluri N, Liu D, Songyang Z.

Cell Discov. 2017 Sep 26;3:17034. doi: 10.1038/celldisc.2017.34. eCollection 2017.


Correction of β-thalassemia mutant by base editor in human embryos.

Liang P, Ding C, Sun H, Xie X, Xu Y, Zhang X, Sun Y, Xiong Y, Ma W, Liu Y, Wang Y, Fang J, Liu D, Songyang Z, Zhou C, Huang J.

Protein Cell. 2017 Nov;8(11):811-822. doi: 10.1007/s13238-017-0475-6. Epub 2017 Sep 23.


Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility.

Chen Y, Liang P, Huang Y, Li M, Zhang X, Ding C, Feng J, Zhang Z, Zhang X, Gao Y, Zhang Q, Cao S, Zheng H, Liu D, Songyang Z, Huang J.

Cell Discov. 2017 Aug 22;3:17030. doi: 10.1038/celldisc.2017.30. eCollection 2017.


Looping-out mechanism for resolution of replicative stress at telomeres.

Zhang T, Zhang Z, Li F, Hu Q, Liu H, Tang M, Ma W, Huang J, Songyang Z, Rong Y, Zhang S, Chen BP, Zhao Y.

EMBO Rep. 2017 Aug;18(8):1412-1428. doi: 10.15252/embr.201643866. Epub 2017 Jun 14.


Effective gene editing by high-fidelity base editor 2 in mouse zygotes.

Liang P, Sun H, Sun Y, Zhang X, Xie X, Zhang J, Zhang Z, Chen Y, Ding C, Xiong Y, Ma W, Liu D, Huang J, Songyang Z.

Protein Cell. 2017 Aug;8(8):601-611. doi: 10.1007/s13238-017-0418-2. Epub 2017 Jun 5.


Rho GDP-dissociation inhibitor α is a potential prognostic biomarker and controls telomere regulation in colorectal cancer.

Huang D, Lu W, Zou S, Wang H, Jiang Y, Zhang X, Li P, Songyang Z, Wang L, Wang J, Huang J, Fang L.

Cancer Sci. 2017 Jul;108(7):1293-1302. doi: 10.1111/cas.13259. Epub 2017 May 31.


Using Protein-Fragment Complementation Assays (PCA) and Peptide Arrays to Study Telomeric Protein-Protein Interactions.

Ma W, Lee OH, Kim H, Songyang Z.

Methods Mol Biol. 2017;1587:147-160. doi: 10.1007/978-1-4939-6892-3_15.


Analysis of Average Telomere Length in Human Telomeric Protein Knockout Cells Generated by CRISPR/Cas9.

Xu J, Songyang Z, Liu D, Kim H.

Methods Mol Biol. 2017;1587:15-28. doi: 10.1007/978-1-4939-6892-3_2.


Introduction to Telomeres and Telomerase.

Songyang Z.

Methods Mol Biol. 2017;1587:1-13. doi: 10.1007/978-1-4939-6892-3_1. Review.


TMEM43/LUMA is a key signaling component mediating EGFR-induced NF-κB activation and tumor progression.

Jiang C, Zhu Y, Zhou Z, Gumin J, Bengtsson L, Wu W, Songyang Z, Lang FF, Lin X.

Oncogene. 2017 May 18;36(20):2813-2823. doi: 10.1038/onc.2016.430. Epub 2016 Dec 19.


Effective production of recipient male pigs for spermatogonial stem cell transplantation by intratesticular injection with busulfan.

Lin Z, Bao J, Kong Q, Bai Y, Luo F, Songyang Z, Wu Y, Huang J.

Theriogenology. 2017 Feb;89:365-373.e2. doi: 10.1016/j.theriogenology.2016.10.021. Epub 2016 Nov 1.


Erratum to: Questions about NgAgo.

Burgess S, Cheng L, Gu F, Huang J, Huang Z, Lin S, Li J, Li W, Qin W, Sun Y, Songyang Z, Wei W, Wu Q, Wang H, Wang X, Xiong JW, Xi J, Yang H, Zhou B, Zhang B.

Protein Cell. 2017 Jan;8(1):77. doi: 10.1007/s13238-016-0349-3. No abstract available.


Questions about NgAgo.

Burgess S, Cheng L, Gu F, Huang J, Huang Z, Lin S, Li J, Li W, Qin W, Sun Y, Songyang Z, Wei W, Wu Q, Wang H, Wang X, Xiong JW, Xi J, Yang H, Zhou B, Zhang B.

Protein Cell. 2016 Dec;7(12):913-915. doi: 10.1007/s13238-016-0343-9. No abstract available. Erratum in: Protein Cell. 2017 Jan;8(1):77.


Regulation of p27Kip1 phosphorylation and G1 cell cycle progression by protein phosphatase PPM1G.

Sun C, Wang G, Wrighton KH, Lin H, Songyang Z, Feng XH, Lin X.

Am J Cancer Res. 2016 Oct 1;6(10):2207-2220. eCollection 2016.


SmedOB1 is Required for Planarian Homeostasis and Regeneration.

Yin S, Huang Y, Zhangfang Y, Zhong X, Li P, Huang J, Liu D, Songyang Z.

Sci Rep. 2016 Sep 22;6:34013. doi: 10.1038/srep34013.


Efficient Production of Gene-Modified Mice using Staphylococcus aureus Cas9.

Zhang X, Liang P, Ding C, Zhang Z, Zhou J, Xie X, Huang R, Sun Y, Sun H, Zhang J, Xu Y, Songyang Z, Huang J.

Sci Rep. 2016 Sep 2;6:32565. doi: 10.1038/srep32565.


Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX.

Hu Y, Shi G, Zhang L, Li F, Jiang Y, Jiang S, Ma W, Zhao Y, Songyang Z, Huang J.

Sci Rep. 2016 Aug 31;6:32280. doi: 10.1038/srep32280.


Ccndbp1 is a new positive regulator of skeletal myogenesis.

Huang Y, Chen B, Ye M, Liang P, Zhangfang Y, Huang J, Liu M, Songyang Z, Ma W.

J Cell Sci. 2016 Jul 15;129(14):2767-77. doi: 10.1242/jcs.184234. Epub 2016 May 27.


CCSI: a database providing chromatin-chromatin spatial interaction information.

Xie X, Ma W, Songyang Z, Luo Z, Huang J, Dai Z, Xiong Y.

Database (Oxford). 2016 Feb 11;2016. pii: bav124. doi: 10.1093/database/bav124. Print 2016.


Specific Tandem 3'UTR Patterns and Gene Expression Profiles in Mouse Thy1+ Germline Stem Cells.

Huang Y, Xiong Y, Lin Z, Feng X, Jiang X, Songyang Z, Huang J.

PLoS One. 2015 Dec 29;10(12):e0145417. doi: 10.1371/journal.pone.0145417. eCollection 2015.


Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner.

Zhang Y, Wu Y, Mao P, Li F, Han X, Zhang Y, Jiang S, Chen Y, Huang J, Liu D, Zhao Y, Ma W, Songyang Z.

Nucleic Acids Res. 2016 Jan 29;44(2):761-75. doi: 10.1093/nar/gkv1465. Epub 2015 Dec 15.


CRISPR/Cas9 Promotes Functional Study of Testis Specific X-Linked Gene In Vivo.

Li M, Huang R, Jiang X, Chen Y, Zhang Z, Zhang X, Liang P, Zhan S, Cao S, Songyang Z, Huang J.

PLoS One. 2015 Nov 24;10(11):e0143148. doi: 10.1371/journal.pone.0143148. eCollection 2015.


The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypomethylation by Promoting H3K9 Trimethylation.

He Q, Kim H, Huang R, Lu W, Tang M, Shi F, Yang D, Zhang X, Huang J, Liu D, Songyang Z.

Cell Stem Cell. 2015 Sep 3;17(3):273-86. doi: 10.1016/j.stem.2015.07.022.


CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes.

Liang P, Xu Y, Zhang X, Ding C, Huang R, Zhang Z, Lv J, Xie X, Chen Y, Li Y, Sun Y, Bai Y, Songyang Z, Ma W, Zhou C, Huang J.

Protein Cell. 2015 May;6(5):363-372. doi: 10.1007/s13238-015-0153-5. Epub 2015 Apr 18.


Actl6a protects embryonic stem cells from differentiating into primitive endoderm.

Lu W, Fang L, Ouyang B, Zhang X, Zhan S, Feng X, Bai Y, Han X, Kim H, He Q, Wan M, Shi FT, Feng XH, Liu D, Huang J, Songyang Z.

Stem Cells. 2015 Jun;33(6):1782-93. doi: 10.1002/stem.2000.


TeloPIN: a database of telomeric proteins interaction network in mammalian cells.

Luo Z, Dai Z, Xie X, Feng X, Liu D, Songyang Z, Xiong Y.

Database (Oxford). 2015 Mar 18;2015. pii: bav018. doi: 10.1093/database/bav018. Print 2015.


Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression.

Luo Z, Feng X, Wang H, Xu W, Zhao Y, Ma W, Jiang S, Liu D, Huang J, Songyang Z.

Aging Cell. 2015 Jun;14(3):391-9. doi: 10.1111/acel.12304. Epub 2015 Mar 6.


Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growth.

Li N, Zhang Y, Han X, Liang K, Wang J, Feng L, Wang W, Songyang Z, Lin C, Yang L, Yu Y, Chen J.

Genes Dev. 2015 Jan 15;29(2):157-70. doi: 10.1101/gad.251785.114. Epub 2014 Dec 29.

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