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Items: 1 to 50 of 205

1.

Intermediacy of Ni-Ni Species in sp2 C-O Bond Cleavage of Aryl Esters: Relevance in Catalytic C-Si Bond Formation.

Somerville RJ, Hale LVA, Gómez-Bengoa E, Burés J, Martin R.

J Am Chem Soc. 2018 Jul 18;140(28):8771-8780. doi: 10.1021/jacs.8b04479. Epub 2018 Jul 2.

PMID:
29909614
2.

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer.

Zacharakis N, Chinnasamy H, Black M, Xu H, Lu YC, Zheng Z, Pasetto A, Langhan M, Shelton T, Prickett T, Gartner J, Jia L, Trebska-McGowan K, Somerville RP, Robbins PF, Rosenberg SA, Goff SL, Feldman SA.

Nat Med. 2018 Jun;24(6):724-730. doi: 10.1038/s41591-018-0040-8. Epub 2018 Jun 4.

PMID:
29867227
3.

T-cell responses to TP53 "hotspot" mutations and unique neoantigens expressed by human ovarian cancers.

Deniger DC, Pasetto A, Robbins PF, Gartner JJ, Prickett TD, Paria BC, Malekzadeh P, Jia L, Yossef R, Langhan MM, Wunderlich JR, Danforth DN, Somerville RPT, Rosenberg SA.

Clin Cancer Res. 2018 May 31. pii: clincanres.0573.2018. doi: 10.1158/1078-0432.CCR-18-0573. [Epub ahead of print]

PMID:
29853601
4.

Childhood central adiposity at ages 5 and 9 shows consistent relationship with that of the maternal grandmother but not other grandparents.

Somerville R, Khalil H, Segurado R, Mehegan J, Viljoen K, Heinen M, Murrin C, Kelleher CC.

Pediatr Obes. 2018 May 9. doi: 10.1111/ijpo.12290. [Epub ahead of print]

PMID:
29745039
5.

Caregiver burden of parents of young children with cystic fibrosis.

Fitzgerald C, George S, Somerville R, Linnane B, Fitzpatrick P.

J Cyst Fibros. 2018 Jan;17(1):125-131. doi: 10.1016/j.jcf.2017.08.016. Epub 2017 Nov 14.

PMID:
29150357
6.

Long-Duration Complete Remissions of Diffuse Large B Cell Lymphoma after Anti-CD19 Chimeric Antigen Receptor T Cell Therapy.

Kochenderfer JN, Somerville RPT, Lu T, Yang JC, Sherry RM, Feldman SA, McIntyre L, Bot A, Rossi J, Lam N, Rosenberg SA.

Mol Ther. 2017 Oct 4;25(10):2245-2253. doi: 10.1016/j.ymthe.2017.07.004. Epub 2017 Jul 13.

PMID:
28803861
7.

Predictors of adults' body mass index and the association with index child's infant birth weight, in the Lifeways Cross-Generation Cohort Study of a thousand families in the Republic of Ireland.

McKey S, Heinen M, Mehegan J, Somerville R, Khalil H, Segurado R, Murrin C, Kelleher CC; Lifeways Cross-Generation Cohort Study Steering Group.

J Dev Orig Health Dis. 2017 Dec;8(6):649-657. doi: 10.1017/S2040174417000435. Epub 2017 Jun 22.

PMID:
28637529
8.

Forging C-C Bonds Through Decarbonylation of Aryl Ketones.

Somerville RJ, Martin R.

Angew Chem Int Ed Engl. 2017 Jun 6;56(24):6708-6710. doi: 10.1002/anie.201702188. Epub 2017 May 3.

PMID:
28466981
9.

Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: a single-centre, two-stage, single-arm, phase 2 study.

Chandran SS, Somerville RPT, Yang JC, Sherry RM, Klebanoff CA, Goff SL, Wunderlich JR, Danforth DN, Zlott D, Paria BC, Sabesan AC, Srivastava AK, Xi L, Pham TH, Raffeld M, White DE, Toomey MA, Rosenberg SA, Kammula US.

Lancet Oncol. 2017 Jun;18(6):792-802. doi: 10.1016/S1470-2045(17)30251-6. Epub 2017 Apr 7.

10.

Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer.

Assadipour Y, Zacharakis N, Crystal JS, Prickett TD, Gartner JJ, Somerville RPT, Xu H, Black MA, Jia L, Chinnasamy H, Kriley I, Lu L, Wunderlich JR, Zheng Z, Lu YC, Robbins PF, Rosenberg SA, Goff SL, Feldman SA.

Clin Cancer Res. 2017 Aug 1;23(15):4347-4353. doi: 10.1158/1078-0432.CCR-16-1423. Epub 2017 Apr 4.

PMID:
28377481
11.

Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels.

Kochenderfer JN, Somerville RPT, Lu T, Shi V, Bot A, Rossi J, Xue A, Goff SL, Yang JC, Sherry RM, Klebanoff CA, Kammula US, Sherman M, Perez A, Yuan CM, Feldman T, Friedberg JW, Roschewski MJ, Feldman SA, McIntyre L, Toomey MA, Rosenberg SA.

J Clin Oncol. 2017 Jun 1;35(16):1803-1813. doi: 10.1200/JCO.2016.71.3024. Epub 2017 Mar 14.

12.

Total HDL cholesterol efflux capacity in healthy children - Associations with adiposity and dietary intakes of mother and child.

Khalil H, Murrin C, O'Reilly M, Viljoen K, Segurado R, O'Brien J, Somerville R, McGillicuddy F, Kelleher CC.

Nutr Metab Cardiovasc Dis. 2017 Jan;27(1):70-77. doi: 10.1016/j.numecd.2016.10.002. Epub 2016 Oct 12.

PMID:
27919542
13.

A Rapid Cell Expansion Process for Production of Engineered Autologous CAR-T Cell Therapies.

Lu TL, Pugach O, Somerville R, Rosenberg SA, Kochenderfer JN, Better M, Feldman SA.

Hum Gene Ther Methods. 2016 Dec;27(6):209-218. Erratum in: Hum Gene Ther Methods. 2017 Apr;28(2):100.

PMID:
27897048
14.
15.

A new species of Pachycara Zugmayer, 1911 (Teleostei: Zoarcidae) from deep-sea chemosynthetic environments in the Caribbean Sea.

Anderson ME, Somerville R, Copley JT.

Zootaxa. 2016 Jan 12;4066(1):71-7. doi: 10.11646/zootaxa.4066.1.5.

PMID:
27395531
16.

Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion.

Benz BA, Nandadasa S, Takeuchi M, Grady RC, Takeuchi H, LoPilato RK, Kakuda S, Somerville RPT, Apte SS, Haltiwanger RS, Holdener BC.

Dev Biol. 2016 Aug 1;416(1):111-122. doi: 10.1016/j.ydbio.2016.05.038. Epub 2016 Jun 10.

17.

Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.

Goff SL, Dudley ME, Citrin DE, Somerville RP, Wunderlich JR, Danforth DN, Zlott DA, Yang JC, Sherry RM, Kammula US, Klebanoff CA, Hughes MS, Restifo NP, Langhan MM, Shelton TE, Lu L, Kwong ML, Ilyas S, Klemen ND, Payabyab EC, Morton KE, Toomey MA, Steinberg SM, White DE, Rosenberg SA.

J Clin Oncol. 2016 Jul 10;34(20):2389-97. doi: 10.1200/JCO.2016.66.7220. Epub 2016 May 23.

18.

Allogeneic T Cells That Express an Anti-CD19 Chimeric Antigen Receptor Induce Remissions of B-Cell Malignancies That Progress After Allogeneic Hematopoietic Stem-Cell Transplantation Without Causing Graft-Versus-Host Disease.

Brudno JN, Somerville RP, Shi V, Rose JJ, Halverson DC, Fowler DH, Gea-Banacloche JC, Pavletic SZ, Hickstein DD, Lu TL, Feldman SA, Iwamoto AT, Kurlander R, Maric I, Goy A, Hansen BG, Wilder JS, Blacklock-Schuver B, Hakim FT, Rosenberg SA, Gress RE, Kochenderfer JN.

J Clin Oncol. 2016 Apr 1;34(10):1112-21. doi: 10.1200/JCO.2015.64.5929. Epub 2016 Jan 25.

19.

Identification of an Immunogenic Subset of Metastatic Uveal Melanoma.

Rothermel LD, Sabesan AC, Stephens DJ, Chandran SS, Paria BC, Srivastava AK, Somerville R, Wunderlich JR, Lee CC, Xi L, Pham TH, Raffeld M, Jailwala P, Kasoji M, Kammula US.

Clin Cancer Res. 2016 May 1;22(9):2237-49. doi: 10.1158/1078-0432.CCR-15-2294. Epub 2015 Dec 28.

20.

Immunogenicity of somatic mutations in human gastrointestinal cancers.

Tran E, Ahmadzadeh M, Lu YC, Gros A, Turcotte S, Robbins PF, Gartner JJ, Zheng Z, Li YF, Ray S, Wunderlich JR, Somerville RP, Rosenberg SA.

Science. 2015 Dec 11;350(6266):1387-90. doi: 10.1126/science.aad1253. Epub 2015 Oct 29.

21.

Carotenemia and hepatomegaly in an atopic child on an exclusion diet for a food allergy.

Gangakhedkar A, Somerville R, Jelleyman T.

Australas J Dermatol. 2017 Feb;58(1):42-44. doi: 10.1111/ajd.12414. Epub 2015 Oct 22. Review.

PMID:
26490299
22.

Poor mental health in severely obese patients is not explained by the presence of comorbidities.

Somerville R, McKenzie K, Eslami S, Breen C, O'Shea D, Wall P.

Clin Obes. 2015 Feb;5(1):12-21. doi: 10.1111/cob.12081. Epub 2014 Dec 22.

PMID:
25530046
23.

Persistence of CTL clones targeting melanocyte differentiation antigens was insufficient to mediate significant melanoma regression in humans.

Chandran SS, Paria BC, Srivastava AK, Rothermel LD, Stephens DJ, Dudley ME, Somerville R, Wunderlich JR, Sherry RM, Yang JC, Rosenberg SA, Kammula US.

Clin Cancer Res. 2015 Feb 1;21(3):534-43. doi: 10.1158/1078-0432.CCR-14-2208. Epub 2014 Nov 25.

24.

Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor.

Kochenderfer JN, Dudley ME, Kassim SH, Somerville RP, Carpenter RO, Stetler-Stevenson M, Yang JC, Phan GQ, Hughes MS, Sherry RM, Raffeld M, Feldman S, Lu L, Li YF, Ngo LT, Goy A, Feldman T, Spaner DE, Wang ML, Chen CC, Kranick SM, Nath A, Nathan DA, Morton KE, Toomey MA, Rosenberg SA.

J Clin Oncol. 2015 Feb 20;33(6):540-9. doi: 10.1200/JCO.2014.56.2025. Epub 2014 Aug 25.

25.

The application of portable microchip electrophoresis for the screening and comparative analysis of synthetic cathinone seizures.

Lloyd A, Russell M, Blanes L, Somerville R, Doble P, Roux C.

Forensic Sci Int. 2014 Sep;242:16-23. doi: 10.1016/j.forsciint.2014.06.013. Epub 2014 Jun 24.

PMID:
25016536
26.

Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer.

Tran E, Turcotte S, Gros A, Robbins PF, Lu YC, Dudley ME, Wunderlich JR, Somerville RP, Hogan K, Hinrichs CS, Parkhurst MR, Yang JC, Rosenberg SA.

Science. 2014 May 9;344(6184):641-5. doi: 10.1126/science.1251102.

27.

Longitudinal follow-up of the relationship between dietary intake and growth and development in the Lifeways cross-generation cohort study 2001-2013.

Kelleher CC, Viljoen K, Khalil H, Somerville R, O'Brien J, Shrivastava A, Murrin C; Lifeways Cross-Generation Cohort Study Steering Group.

Proc Nutr Soc. 2014 Feb;73(1):118-31. doi: 10.1017/S002966511300373X. Epub 2013 Dec 3.

PMID:
24300176
28.

Non-pulmonary chronic diseases in adults with cystic fibrosis: analysis of data from the Cystic Fibrosis Registry.

Somerville R, Lackson A, Zhou S, Fletcher C, Fitzpatrick P.

Ir Med J. 2013 Jun;106(6):166-8.

PMID:
23909150
29.

How independent are TSE agents from their hosts?

Somerville RA.

Prion. 2013 Jul-Aug;7(4):272-5. doi: 10.4161/pri.25420. Epub 2013 Jun 18. Review.

30.

From lipoproteins to chondrocytes: a brief summary of the European Medicines Agency's regulatory guidelines for advanced therapy medicinal products.

Kassim SH, Somerville RP.

Hum Gene Ther. 2013 Jun;24(6):568-70. doi: 10.1089/hum.2013.101. No abstract available.

31.

Randomized selection design trial evaluating CD8+-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma.

Dudley ME, Gross CA, Somerville RP, Hong Y, Schaub NP, Rosati SF, White DE, Nathan D, Restifo NP, Steinberg SM, Wunderlich JR, Kammula US, Sherry RM, Yang JC, Phan GQ, Hughes MS, Laurencot CM, Rosenberg SA.

J Clin Oncol. 2013 Jun 10;31(17):2152-9. doi: 10.1200/JCO.2012.46.6441. Epub 2013 May 6.

32.

Post-translational changes to PrP alter transmissible spongiform encephalopathy strain properties.

Cancellotti E, Mahal SP, Somerville R, Diack A, Brown D, Piccardo P, Weissmann C, Manson JC.

EMBO J. 2013 Mar 6;32(5):756-69. doi: 10.1038/emboj.2013.6. Epub 2013 Feb 8.

33.

Quantitative analysis of wet-heat inactivation in bovine spongiform encephalopathy.

Matsuura Y, Ishikawa Y, Bo X, Murayama Y, Yokoyama T, Somerville RA, Kitamoto T, Mohri S.

Biochem Biophys Res Commun. 2013 Mar 1;432(1):86-91. doi: 10.1016/j.bbrc.2013.01.081. Epub 2013 Jan 30.

PMID:
23376069
34.

Bioreactors get personal.

Somerville RP, Dudley ME.

Oncoimmunology. 2012 Nov 1;1(8):1435-1437.

35.

Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE® bioreactor.

Somerville RP, Devillier L, Parkhurst MR, Rosenberg SA, Dudley ME.

J Transl Med. 2012 Apr 4;10:69. doi: 10.1186/1479-5876-10-69.

36.

Simplified method of the growth of human tumor infiltrating lymphocytes in gas-permeable flasks to numbers needed for patient treatment.

Jin J, Sabatino M, Somerville R, Wilson JR, Dudley ME, Stroncek DF, Rosenberg SA.

J Immunother. 2012 Apr;35(3):283-92. doi: 10.1097/CJI.0b013e31824e801f.

37.

Larazotide acetate regulates epithelial tight junctions in vitro and in vivo.

Gopalakrishnan S, Durai M, Kitchens K, Tamiz AP, Somerville R, Ginski M, Paterson BM, Murray JA, Verdu EF, Alkan SS, Pandey NB.

Peptides. 2012 May;35(1):86-94. doi: 10.1016/j.peptides.2012.02.015. Epub 2012 Feb 27.

PMID:
22401908
38.

Limited efficacy of steam sterilization to inactivate vCJD infectivity.

Fernie K, Hamilton S, Somerville RA.

J Hosp Infect. 2012 Jan;80(1):46-51. doi: 10.1016/j.jhin.2011.09.004. Epub 2011 Nov 17.

PMID:
22099953
39.

Characterization of the effect of heat on agent strains of the transmissible spongiform encephalopathies.

Somerville RA, Gentles N.

J Gen Virol. 2011 Jul;92(Pt 7):1738-48. doi: 10.1099/vir.0.030452-0. Epub 2011 Apr 6.

PMID:
21471321
40.

Time to take action on climate communication.

Bowman TE, Maibach E, Mann ME, Somerville RC, Seltser BJ, Fischhoff B, Gardiner SM, Gould RJ, Leiserowitz A, Yohe G.

Science. 2010 Nov 19;330(6007):1044. doi: 10.1126/science.330.6007.1044. No abstract available.

PMID:
21097916
41.

Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation.

Enomoto H, Nelson CM, Somerville RP, Mielke K, Dixon LJ, Powell K, Apte SS.

Development. 2010 Dec;137(23):4029-38. doi: 10.1242/dev.050591. Epub 2010 Nov 1.

42.

Transport of the pathogenic prion protein through soils.

Jacobson KH, Lee S, Somerville RA, McKenzie D, Benson CH, Pedersen JA.

J Environ Qual. 2010 Jul-Aug;39(4):1145-52.

43.

Risk of escape of prions in gaseous emissions from on-farm digestion vessels.

Adkin A, Matthews D, Hope J, Maddison BC, Somerville RA, Pedersen J.

Vet Rec. 2010 Jul 3;167(1):28-9. doi: 10.1136/vr.c3158. No abstract available.

PMID:
20605957
44.

ADAMTS9 is a cell-autonomously acting, anti-angiogenic metalloprotease expressed by microvascular endothelial cells.

Koo BH, Coe DM, Dixon LJ, Somerville RP, Nelson CM, Wang LW, Young ME, Lindner DJ, Apte SS.

Am J Pathol. 2010 Mar;176(3):1494-504. doi: 10.2353/ajpath.2010.090655. Epub 2010 Jan 21.

45.

Application of two low-cost adsorption media for removal of toxic metals from contaminated water.

Somerville R, Norrström AC.

Water Sci Technol. 2009;60(4):935-42. doi: 10.2166/wst.2009.415.

PMID:
19700832
46.

Creating a common climate language.

Bowman TE, Maibach E, Mann ME, Moser SC, Somerville RC.

Science. 2009 Apr 3;324(5923):36-7. doi: 10.1126/science.324.5923.36b. No abstract available. Erratum in: Science. 2009 Jun 12;324(5933):1391.

PMID:
19342569
47.

Mechanism of action of ZOT-derived peptide AT-1002, a tight junction regulator and absorption enhancer.

Gopalakrishnan S, Pandey N, Tamiz AP, Vere J, Carrasco R, Somerville R, Tripathi A, Ginski M, Paterson BM, Alkan SS.

Int J Pharm. 2009 Jan 5;365(1-2):121-30. doi: 10.1016/j.ijpharm.2008.08.047. Epub 2008 Sep 11.

PMID:
18832018
48.

The secreted metalloprotease ADAMTS20 is required for melanoblast survival.

Silver DL, Hou L, Somerville R, Young ME, Apte SS, Pavan WJ.

PLoS Genet. 2008 Feb 29;4(2):e1000003. doi: 10.1371/journal.pgen.1000003.

49.

Infants hospitalised with pertussis: estimating the true disease burden.

Somerville RL, Grant CC, Grimwood K, Murdoch D, Graham D, Jackson P, Meates-Dennis M, Nicholson R, Purvis D.

J Paediatr Child Health. 2007 Sep;43(9):617-22. Epub 2007 Jun 29.

PMID:
17608654
50.

Regulation of ADAMTS9 secretion and enzymatic activity by its propeptide.

Koo BH, Longpré JM, Somerville RP, Alexander JP, Leduc R, Apte SS.

J Biol Chem. 2007 Jun 1;282(22):16146-54. Epub 2007 Apr 2.

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