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Items: 42

1.

Molecular footprint of Medawar's mutation accumulation process in mammalian aging.

Turan ZG, Parvizi P, Dönertaş HM, Tung J, Khaitovich P, Somel M.

Aging Cell. 2019 May 6:e12965. doi: 10.1111/acel.12965. [Epub ahead of print]

2.

Ancient Mitochondrial Genomes Reveal the Absence of Maternal Kinship in the Burials of Çatalhöyük People and Their Genetic Affinities.

Chyleński M, Ehler E, Somel M, Yaka R, Krzewińska M, Dabert M, Juras A, Marciniak A.

Genes (Basel). 2019 Mar 11;10(3). pii: E207. doi: 10.3390/genes10030207.

3.

Genomic and Strontium Isotope Variation Reveal Immigration Patterns in a Viking Age Town.

Krzewińska M, Kjellström A, Günther T, Hedenstierna-Jonson C, Zachrisson T, Omrak A, Yaka R, Kılınç GM, Somel M, Sobrado V, Evans J, Knipper C, Jakobsson M, Storå J, Götherström A.

Curr Biol. 2018 Sep 10;28(17):2730-2738.e10. doi: 10.1016/j.cub.2018.06.053. Epub 2018 Aug 23.

4.

Investigating Holocene human population history in North Asia using ancient mitogenomes.

Kılınç GM, Kashuba N, Yaka R, Sümer AP, Yüncü E, Shergin D, Ivanov GL, Kichigin D, Pestereva K, Volkov D, Mandryka P, Kharinskii A, Tishkin A, Ineshin E, Kovychev E, Stepanov A, Alekseev A, Fedoseeva SA, Somel M, Jakobsson M, Krzewińska M, Storå J, Götherström A.

Sci Rep. 2018 Jun 12;8(1):8969. doi: 10.1038/s41598-018-27325-0.

5.

Archaeogenetics of Late Iron Age Çemialo Sırtı, Batman: Investigating maternal genetic continuity in north Mesopotamia since the Neolithic.

Yaka R, Birand A, Yılmaz Y, Caner C, Açan SC, Gündüzalp S, Parvizi P, Erim Özdoğan A, Togan İ, Somel M.

Am J Phys Anthropol. 2018 May;166(1):196-207. doi: 10.1002/ajpa.23423. Epub 2018 Feb 5.

PMID:
29399779
6.

Archaeogenomic analysis of the first steps of Neolithization in Anatolia and the Aegean.

Kılınç GM, Koptekin D, Atakuman Ç, Sümer AP, Dönertaş HM, Yaka R, Bilgin CC, Büyükkarakaya AM, Baird D, Altınışık E, Flegontov P, Götherström A, Togan İ, Somel M.

Proc Biol Sci. 2017 Nov 29;284(1867). pii: 20172064. doi: 10.1098/rspb.2017.2064.

7.

Variation and Functional Impact of Neanderthal Ancestry in Western Asia.

Taskent RO, Alioglu ND, Fer E, Melike Donertas H, Somel M, Gokcumen O.

Genome Biol Evol. 2017 Dec 1;9(12):3516-3524. doi: 10.1093/gbe/evx216.

8.

Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity.

Dönertaş HM, İzgi H, Kamacıoğlu A, He Z, Khaitovich P, Somel M.

Sci Rep. 2017 Jul 19;7(1):5894. doi: 10.1038/s41598-017-05927-4.

9.

Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism.

Liu X, Han D, Somel M, Jiang X, Hu H, Guijarro P, Zhang N, Mitchell A, Halene T, Ely JJ, Sherwood CC, Hof PR, Qiu Z, Pääbo S, Akbarian S, Khaitovich P.

PLoS Biol. 2016 Sep 29;14(9):e1002558. doi: 10.1371/journal.pbio.1002558. eCollection 2016 Sep.

10.

The Demographic Development of the First Farmers in Anatolia.

Kılınç GM, Omrak A, Özer F, Günther T, Büyükkarakaya AM, Bıçakçı E, Baird D, Dönertaş HM, Ghalichi A, Yaka R, Koptekin D, Açan SC, Parvizi P, Krzewińska M, Daskalaki EA, Yüncü E, Dağtaş ND, Fairbairn A, Pearson J, Mustafaoğlu G, Erdal YS, Çakan YG, Togan İ, Somel M, Storå J, Jakobsson M, Götherström A.

Curr Biol. 2016 Oct 10;26(19):2659-2666. doi: 10.1016/j.cub.2016.07.057. Epub 2016 Aug 4.

11.

Determining the origin of synchronous multifocal bladder cancer by exome sequencing.

Acar Ö, Özkurt E, Demir G, Saraç H, Alkan C, Esen T, Somel M, Lack NA.

BMC Cancer. 2015 Nov 9;15:871. doi: 10.1186/s12885-015-1859-8.

12.

Whole genome sequencing of Turkish genomes reveals functional private alleles and impact of genetic interactions with Europe, Asia and Africa.

Alkan C, Kavak P, Somel M, Gokcumen O, Ugurlu S, Saygi C, Dal E, Bugra K, Güngör T, Sahinalp SC, Özören N, Bekpen C.

BMC Genomics. 2014 Nov 7;15:963. doi: 10.1186/1471-2164-15-963.

13.

Transcriptomic insights into human brain evolution: acceleration, neutrality, heterochrony.

Somel M, Rohlfs R, Liu X.

Curr Opin Genet Dev. 2014 Dec;29:110-9. doi: 10.1016/j.gde.2014.09.001. Epub 2014 Sep 16. Review.

PMID:
25233113
14.

Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA.

Huerta-Sánchez E, Jin X, Asan, Bianba Z, Peter BM, Vinckenbosch N, Liang Y, Yi X, He M, Somel M, Ni P, Wang B, Ou X, Huasang, Luosang J, Cuo ZX, Li K, Gao G, Yin Y, Wang W, Zhang X, Xu X, Yang H, Li Y, Wang J, Wang J, Nielsen R.

Nature. 2014 Aug 14;512(7513):194-7. doi: 10.1038/nature13408. Epub 2014 Jul 2.

15.

Shared signatures of social stress and aging in peripheral blood mononuclear cell gene expression profiles.

Snyder-Mackler N, Somel M, Tung J.

Aging Cell. 2014 Oct;13(5):954-7. doi: 10.1111/acel.12239. Epub 2014 Jun 23.

16.

Population genomics reveal recent speciation and rapid evolutionary adaptation in polar bears.

Liu S, Lorenzen ED, Fumagalli M, Li B, Harris K, Xiong Z, Zhou L, Korneliussen TS, Somel M, Babbitt C, Wray G, Li J, He W, Wang Z, Fu W, Xiang X, Morgan CC, Doherty A, O'Connell MJ, McInerney JO, Born EW, Dalén L, Dietz R, Orlando L, Sonne C, Zhang G, Nielsen R, Willerslev E, Wang J.

Cell. 2014 May 8;157(4):785-94. doi: 10.1016/j.cell.2014.03.054.

17.

Classic selective sweeps revealed by massive sequencing in cattle.

Qanbari S, Pausch H, Jansen S, Somel M, Strom TM, Fries R, Nielsen R, Simianer H.

PLoS Genet. 2014 Feb 27;10(2):e1004148. doi: 10.1371/journal.pgen.1004148. eCollection 2014 Feb.

18.

Evolution of human longevity uncoupled from caloric restriction mechanisms.

Zhao G, Guo S, Somel M, Khaitovich P.

PLoS One. 2014 Jan 6;9(1):e84117. doi: 10.1371/journal.pone.0084117. eCollection 2014.

19.

A scan for human-specific relaxation of negative selection reveals unexpected polymorphism in proteasome genes.

Somel M, Wilson Sayres MA, Jordan G, Huerta-Sanchez E, Fumagalli M, Ferrer-Admetlla A, Nielsen R.

Mol Biol Evol. 2013 Aug;30(8):1808-15. doi: 10.1093/molbev/mst098. Epub 2013 May 22.

20.

Early gene expression divergence between allopatric populations of the house mouse (Mus musculus domesticus).

Bryk J, Somel M, Lorenc A, Teschke M.

Ecol Evol. 2013 Mar;3(3):558-68. doi: 10.1002/ece3.447. Epub 2013 Jan 31.

21.

Widespread splicing changes in human brain development and aging.

Mazin P, Xiong J, Liu X, Yan Z, Zhang X, Li M, He L, Somel M, Yuan Y, Phoebe Chen YP, Li N, Hu Y, Fu N, Ning Z, Zeng R, Yang H, Chen W, Gelfand M, Khaitovich P.

Mol Syst Biol. 2013;9:633. doi: 10.1038/msb.2012.67.

22.

Human brain evolution: transcripts, metabolites and their regulators.

Somel M, Liu X, Khaitovich P.

Nat Rev Neurosci. 2013 Feb;14(2):112-27. doi: 10.1038/nrn3372. Epub 2013 Jan 17. Review.

PMID:
23324662
23.

A comparison of brain gene expression levels in domesticated and wild animals.

Albert FW, Somel M, Carneiro M, Aximu-Petri A, Halbwax M, Thalmann O, Blanco-Aguiar JA, Plyusnina IZ, Trut L, Villafuerte R, Ferrand N, Kaiser S, Jensen P, Pääbo S.

PLoS Genet. 2012 Sep;8(9):e1002962. doi: 10.1371/journal.pgen.1002962. Epub 2012 Sep 27.

24.

Mechanisms of dietary response in mice and primates: a role for EGR1 in regulating the reaction to human-specific nutritional content.

Weng K, Hu H, Xu AG, Khaitovich P, Somel M.

PLoS One. 2012;7(8):e43915. doi: 10.1371/journal.pone.0043915. Epub 2012 Aug 24.

25.

Accelerated aging-related transcriptome changes in the female prefrontal cortex.

Yuan Y, Chen YP, Boyd-Kirkup J, Khaitovich P, Somel M.

Aging Cell. 2012 Oct;11(5):894-901. doi: 10.1111/j.1474-9726.2012.00859.x. Epub 2012 Aug 2.

26.

Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques.

Liu X, Somel M, Tang L, Yan Z, Jiang X, Guo S, Yuan Y, He L, Oleksiak A, Zhang Y, Li N, Hu Y, Chen W, Qiu Z, Pääbo S, Khaitovich P.

Genome Res. 2012 Apr;22(4):611-22. doi: 10.1101/gr.127324.111. Epub 2012 Feb 2.

27.

MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates.

Somel M, Liu X, Tang L, Yan Z, Hu H, Guo S, Jiang X, Zhang X, Xu G, Xie G, Li N, Hu Y, Chen W, Pääbo S, Khaitovich P.

PLoS Biol. 2011 Dec;9(12):e1001214. doi: 10.1371/journal.pbio.1001214. Epub 2011 Dec 6.

28.

Development and application of a modified dynamic time warping algorithm (DTW-S) to analyses of primate brain expression time series.

Yuan Y, Chen YP, Ni S, Xu AG, Tang L, Vingron M, Somel M, Khaitovich P.

BMC Bioinformatics. 2011 Aug 18;12:347. doi: 10.1186/1471-2105-12-347.

29.

Rapid metabolic evolution in human prefrontal cortex.

Fu X, Giavalisco P, Liu X, Catchpole G, Fu N, Ning ZB, Guo S, Yan Z, Somel M, Pääbo S, Zeng R, Willmitzer L, Khaitovich P.

Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6181-6. doi: 10.1073/pnas.1019164108. Epub 2011 Mar 28.

30.

MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain.

Somel M, Guo S, Fu N, Yan Z, Hu HY, Xu Y, Yuan Y, Ning Z, Hu Y, Menzel C, Hu H, Lachmann M, Zeng R, Chen W, Khaitovich P.

Genome Res. 2010 Sep;20(9):1207-18. doi: 10.1101/gr.106849.110. Epub 2010 Jul 20.

31.

Evolution of neuronal and endothelial transcriptomes in primates.

Giger T, Khaitovich P, Somel M, Lorenc A, Lizano E, Harris LW, Ryan MM, Lan M, Wayland MT, Bahn S, Pääbo S.

Genome Biol Evol. 2010 Jul 12;2:284-92. doi: 10.1093/gbe/evq018.

32.

Intergenic and repeat transcription in human, chimpanzee and macaque brains measured by RNA-Seq.

Xu AG, He L, Li Z, Xu Y, Li M, Fu X, Yan Z, Yuan Y, Menzel C, Li N, Somel M, Hu H, Chen W, Pääbo S, Khaitovich P.

PLoS Comput Biol. 2010 Jul 1;6:e1000843. doi: 10.1371/journal.pcbi.1000843.

33.

A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice.

Enard W, Gehre S, Hammerschmidt K, Hölter SM, Blass T, Somel M, Brückner MK, Schreiweis C, Winter C, Sohr R, Becker L, Wiebe V, Nickel B, Giger T, Müller U, Groszer M, Adler T, Aguilar A, Bolle I, Calzada-Wack J, Dalke C, Ehrhardt N, Favor J, Fuchs H, Gailus-Durner V, Hans W, Hölzlwimmer G, Javaheri A, Kalaydjiev S, Kallnik M, Kling E, Kunder S, Mossbrugger I, Naton B, Racz I, Rathkolb B, Rozman J, Schrewe A, Busch DH, Graw J, Ivandic B, Klingenspor M, Klopstock T, Ollert M, Quintanilla-Martinez L, Schulz H, Wolf E, Wurst W, Zimmer A, Fisher SE, Morgenstern R, Arendt T, de Angelis MH, Fischer J, Schwarz J, Pääbo S.

Cell. 2009 May 29;137(5):961-71. doi: 10.1016/j.cell.2009.03.041.

34.

Transcriptional neoteny in the human brain.

Somel M, Franz H, Yan Z, Lorenc A, Guo S, Giger T, Kelso J, Nickel B, Dannemann M, Bahn S, Webster MJ, Weickert CS, Lachmann M, Pääbo S, Khaitovich P.

Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5743-8. doi: 10.1073/pnas.0900544106. Epub 2009 Mar 23.

35.

Evolution of primate gene expression: drift and corrective sweeps?

Chaix R, Somel M, Kreil DP, Khaitovich P, Lunter GA.

Genetics. 2008 Nov;180(3):1379-89. doi: 10.1534/genetics.108.089623. Epub 2008 Sep 14.

36.

Metabolic changes in schizophrenia and human brain evolution.

Khaitovich P, Lockstone HE, Wayland MT, Tsang TM, Jayatilaka SD, Guo AJ, Zhou J, Somel M, Harris LW, Holmes E, Pääbo S, Bahn S.

Genome Biol. 2008;9(8):R124. doi: 10.1186/gb-2008-9-8-r124. Epub 2008 Aug 5.

37.

Human and chimpanzee gene expression differences replicated in mice fed different diets.

Somel M, Creely H, Franz H, Mueller U, Lachmann M, Khaitovich P, Pääbo S.

PLoS One. 2008 Jan 30;3(1):e1504. doi: 10.1371/journal.pone.0001504.

38.

Identification and analysis of genomic regions with large between-population differentiation in humans.

Myles S, Tang K, Somel M, Green RE, Kelso J, Stoneking M.

Ann Hum Genet. 2008 Jan;72(Pt 1):99-110. doi: 10.1111/j.1469-1809.2007.00390.x.

39.

Turks fighting back against anti-evolution forces.

Somel M, Somel RN, Kence A.

Nature. 2007 Jan 11;445(7124):147. No abstract available.

PMID:
17215823
40.

Identifying genes underlying skin pigmentation differences among human populations.

Myles S, Somel M, Tang K, Kelso J, Stoneking M.

Hum Genet. 2007 Jan;120(5):613-21. Epub 2006 Sep 15.

PMID:
16977434
41.

Gene expression becomes heterogeneous with age.

Somel M, Khaitovich P, Bahn S, Pääbo S, Lachmann M.

Curr Biol. 2006 May 23;16(10):R359-60. No abstract available.

42.

Turkish science needs more than membership of the EU.

Somel M.

Nature. 2005 Dec 8;438(7069):738. No abstract available.

PMID:
16340989

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