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Items: 1 to 50 of 175

1.

Remodeling of the collagen matrix in aging skin promotes melanoma metastasis and affects immune cell motility.

Kaur A, Ecker BL, Douglass SM, Kugel CH, Webster MR, Almeida FV, Somasundaram R, Hayden J, Ban E, Ahmadzadeh H, Franco-Barraza J, Shah N, Mellis IA, Keeney F, Kossenkov A, Tang HY, Yin X, Liu Q, Xu X, Fane M, Brafford P, Herlyn M, Speicher DW, Wargo JA, Tetzlaff MT, Haydu LE, Raj A, Shenoy V, Cukierman E, Weeraratna AT.

Cancer Discov. 2018 Oct 2. pii: CD-18-0193. doi: 10.1158/2159-8290.CD-18-0193. [Epub ahead of print]

PMID:
30279173
2.

Evidence for Seasonal Variation of Bell's Palsy in Germany.

Erdur H, Ernst S, Ahmadi M, Albers AE, Marzinzik F, Somasundaram R, Audebert HJ, Weber JE.

Neuroepidemiology. 2018 Aug 9;51(3-4):128-130. doi: 10.1159/000492097. [Epub ahead of print] No abstract available.

3.

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response.

Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W.

Nature. 2018 Aug;560(7718):382-386. doi: 10.1038/s41586-018-0392-8. Epub 2018 Aug 8.

PMID:
30089911
4.

Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis.

Jensen CT, Åhsberg J, Sommarin MNE, Strid T, Somasundaram R, Okuyama K, Ungerbäck J, Kupari J, Airaksinen MS, Lang S, Bryder D, Soneji S, Karlsson G, Sigvardsson M.

J Exp Med. 2018 Jul 2;215(7):1947-1963. doi: 10.1084/jem.20171384. Epub 2018 Jun 13.

PMID:
29899037
5.

Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations.

Kugel CH 3rd, Douglass SM, Webster MR, Kaur A, Liu Q, Yin X, Weiss SA, Darvishian F, Al-Rohil RN, Ndoye A, Behera R, Alicea GM, Ecker BL, Fane M, Allegrezza MJ, Svoronos N, Kumar V, Wang DY, Somasundaram R, Hu-Lieskovan S, Ozgun A, Herlyn M, Conejo-Garcia JR, Gabrilovich D, Stone EL, Nowicki TS, Sosman J, Rai R, Carlino MS, Long GV, Marais R, Ribas A, Eroglu Z, Davies MA, Schilling B, Schadendorf D, Xu W, Amaravadi RK, Menzies AM, McQuade JL, Johnson DB, Osman I, Weeraratna AT.

Clin Cancer Res. 2018 Jun 13. doi: 10.1158/1078-0432.CCR-18-1116. [Epub ahead of print]

PMID:
29898988
6.

Co-targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor-resistant melanoma.

Echevarría-Vargas IM, Reyes-Uribe PI, Guterres AN, Yin X, Kossenkov AV, Liu Q, Zhang G, Krepler C, Cheng C, Wei Z, Somasundaram R, Karakousis G, Xu W, Morrissette JJ, Lu Y, Mills GB, Sullivan RJ, Benchun M, Frederick DT, Boland G, Flaherty KT, Weeraratna AT, Herlyn M, Amaravadi R, Schuchter LM, Burd CE, Aplin AE, Xu X, Villanueva J.

EMBO Mol Med. 2018 May;10(5). pii: e8446. doi: 10.15252/emmm.201708446.

7.

Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma.

Zhang G, Wu LW, Mender I, Barzily-Rokni M, Hammond MR, Ope O, Cheng C, Vasilopoulos T, Randell S, Sadek N, Beroard A, Xiao M, Tian T, Tan J, Saeed U, Sugarman E, Krepler C, Brafford P, Sproesser K, Murugan S, Somasundaram R, Garman B, Wubbenhorst B, Woo J, Yin X, Liu Q, Frederick DT, Miao B, Xu W, Karakousis GC, Xu X, Schuchter LM, Mitchell TC, Kwong LN, Amaravadi RK, Lu Y, Boland GM, Wei Z, Nathanson K, Herbig U, Mills GB, Flaherty KT, Herlyn M, Shay JW.

Clin Cancer Res. 2018 Oct 1;24(19):4771-4784. doi: 10.1158/1078-0432.CCR-17-2773. Epub 2018 Mar 21.

PMID:
29563139
8.

Suitability of current definitions of ambulatory care sensitive conditions for research in emergency department patients: a secondary health data analysis.

Frick J, Möckel M, Muller R, Searle J, Somasundaram R, Slagman A.

BMJ Open. 2017 Oct 22;7(10):e016109. doi: 10.1136/bmjopen-2017-016109.

9.

Tumor-associated B-cells induce tumor heterogeneity and therapy resistance.

Somasundaram R, Zhang G, Fukunaga-Kalabis M, Perego M, Krepler C, Xu X, Wagner C, Hristova D, Zhang J, Tian T, Wei Z, Liu Q, Garg K, Griss J, Hards R, Maurer M, Hafner C, Mayerhöfer M, Karanikas G, Jalili A, Bauer-Pohl V, Weihsengruber F, Rappersberger K, Koller J, Lang R, Hudgens C, Chen G, Tetzlaff M, Wu L, Frederick DT, Scolyer RA, Long GV, Damle M, Ellingsworth C, Grinman L, Choi H, Gavin BJ, Dunagin M, Raj A, Scholler N, Gross L, Beqiri M, Bennett K, Watson I, Schaider H, Davies MA, Wargo J, Czerniecki BJ, Schuchter L, Herlyn D, Flaherty K, Herlyn M, Wagner SN.

Nat Commun. 2017 Sep 19;8(1):607. doi: 10.1038/s41467-017-00452-4.

10.

A slow-cycling subpopulation of melanoma cells with highly invasive properties.

Perego M, Maurer M, Wang JX, Shaffer S, Müller AC, Parapatics K, Li L, Hristova D, Shin S, Keeney F, Liu S, Xu X, Raj A, Jensen JK, Bennett KL, Wagner SN, Somasundaram R, Herlyn M.

Oncogene. 2018 Jan 18;37(3):302-312. doi: 10.1038/onc.2017.341. Epub 2017 Sep 18.

11.
12.

Analysis of SHIP1 expression and activity in Crohn's disease patients.

Somasundaram R, Fernandes S, Deuring JJ, de Haar C, Kuipers EJ, Vogelaar L, Middleton FA, van der Woude CJ, Peppelenbosch MP, Kerr WG, Fuhler GM.

PLoS One. 2017 Aug 2;12(8):e0182308. doi: 10.1371/journal.pone.0182308. eCollection 2017.

13.

The Multifaceted Roles of B Cells in Solid Tumors: Emerging Treatment Opportunities.

Flynn NJ, Somasundaram R, Arnold KM, Sims-Mourtada J.

Target Oncol. 2017 Apr;12(2):139-152. doi: 10.1007/s11523-017-0481-x. Review.

PMID:
28281220
14.

Cellular plasticity in B-cell leukemia.

Somasundaram R, Strid T, Sigvardsson M.

Cell Cycle. 2017 Mar 19;16(6):495-496. doi: 10.1080/15384101.2017.1285635. Epub 2017 Jan 24. No abstract available.

15.

Clonal conversion of B lymphoid leukemia reveals cross-lineage transfer of malignant states.

Somasundaram R, Åhsberg J, Okuyama K, Ungerbäck J, Lilljebjörn H, Fioretos T, Strid T, Sigvardsson M.

Genes Dev. 2016 Nov 15;30(22):2486-2499. Epub 2016 Dec 2.

16.

Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia.

Hu Y, Zhang Z, Kashiwagi M, Yoshida T, Joshi I, Jena N, Somasundaram R, Emmanuel AO, Sigvardsson M, Fitamant J, El-Bardeesy N, Gounari F, Van Etten RA, Georgopoulos K.

Genes Dev. 2016 Sep 1;30(17):1971-90. doi: 10.1101/gad.283762.116.

17.

[Reasons for Emergency Department Visits: Results of a Patient Survey].

Somasundaram R, Geissler A, Leidel BA, Wrede CE.

Gesundheitswesen. 2018 Jul;80(7):621-627. doi: 10.1055/s-0042-112459. Epub 2016 Sep 9. German.

PMID:
27611882
18.

Identification of Stage-Specific Surface Markers in Early B Cell Development Provides Novel Tools for Identification of Progenitor Populations.

Jensen CT, Lang S, Somasundaram R, Soneji S, Sigvardsson M.

J Immunol. 2016 Sep 1;197(5):1937-44. doi: 10.4049/jimmunol.1600297. Epub 2016 Jul 25.

19.

Subcellular differential expression of Ep-ICD in oral dysplasia and cancer is associated with disease progression and prognosis.

Somasundaram RT, Kaur J, Leong I, MacMillan C, Witterick IJ, Walfish PG, Ralhan R.

BMC Cancer. 2016 Jul 16;16:486. doi: 10.1186/s12885-016-2507-7.

20.

Antioxidant and cyto/DNA protective properties of apple pomace enriched bakery products.

Sudha ML, Dharmesh SM, Pynam H, Bhimangouder SV, Eipson SW, Somasundaram R, Nanjarajurs SM.

J Food Sci Technol. 2016 Apr;53(4):1909-18. doi: 10.1007/s13197-015-2151-2. Epub 2016 Apr 16.

21.

A Comparative Study on Resilience, Perceived Social Support and Hopelessness Among Cancer Patients Treated with Curative and Palliative Care.

Somasundaram RO, Devamani KA.

Indian J Palliat Care. 2016 Apr-Jun;22(2):135-40. doi: 10.4103/0973-1075.179606.

22.

[Patients with Acute, Non-Traumatic Abdominal Pain in German Emergency Departments: A Prospective Monocentric Observation Study].

Kulla M, Kraus S, Walcher F, Somasundaram R, Wrede CE, Lampl L, Helm M.

Zentralbl Chir. 2016 Dec;141(6):666-676. Epub 2016 May 2. German.

PMID:
27135864
23.

ER maleate is a novel anticancer agent in oral cancer: implications for cancer therapy.

Fu G, Somasundaram RT, Jessa F, Srivastava G, MacMillan C, Witterick I, Walfish PG, Ralhan R.

Oncotarget. 2016 Mar 29;7(13):17162-81. doi: 10.18632/oncotarget.7751.

24.

The role of tumor microenvironment in melanoma therapy resistance.

Somasundaram R, Herlyn M, Wagner SN.

Melanoma Manag. 2016 Mar;3(1):23-32. doi: 10.2217/mmt.15.37. Epub 2016 Feb 12. Review.

25.

Heterogeneity in Melanoma.

Shannan B, Perego M, Somasundaram R, Herlyn M.

Cancer Treat Res. 2016;167:1-15. doi: 10.1007/978-3-319-22539-5_1. Review.

PMID:
26601857
26.

Type I-polarized BRAF-pulsed dendritic cells induce antigen-specific CD8+ T cells that impact BRAF-mutant murine melanoma.

Cintolo JA, Datta J, Xu S, Gupta M, Somasundaram R, Czerniecki BJ.

Melanoma Res. 2016 Feb;26(1):1-11. doi: 10.1097/CMR.0000000000000203.

PMID:
26451873
27.

Nivolumab in combination with ipilimumab for the treatment of melanoma.

Somasundaram R, Herlyn M.

Expert Rev Anticancer Ther. 2015;15(10):1135-41. doi: 10.1586/14737140.2015.1093418. Review.

28.

Anticancer Activity of Apaziquone in Oral Cancer Cells and Xenograft Model: Implications for Oral Cancer Therapy.

Srivastava G, Somasundaram RT, Walfish PG, Ralhan R.

PLoS One. 2015 Jul 24;10(7):e0133735. doi: 10.1371/journal.pone.0133735. eCollection 2015.

29.

Immunohistochemical Subcellular Localization of Protein Biomarkers Distinguishes Benign from Malignant Thyroid Nodules: Potential for Fine-Needle Aspiration Biopsy Clinical Application.

Ralhan R, Veyhl J, Chaker S, Assi J, Alyass A, Jeganathan A, Somasundaram RT, MacMillan C, Freeman J, Vescan AD, Witterick IJ, Walfish PG.

Thyroid. 2015 Nov;25(11):1224-34. doi: 10.1089/thy.2015.0114. Epub 2015 Aug 6.

PMID:
26131603
30.

Anticancer activity of pyrithione zinc in oral cancer cells identified in small molecule screens and xenograft model: Implications for oral cancer therapy.

Srivastava G, Matta A, Fu G, Somasundaram RT, Datti A, Walfish PG, Ralhan R.

Mol Oncol. 2015 Oct;9(8):1720-35. doi: 10.1016/j.molonc.2015.05.005. Epub 2015 May 21.

31.

Combined heterozygous loss of Ebf1 and Pax5 allows for T-lineage conversion of B cell progenitors.

Ungerbäck J, Åhsberg J, Strid T, Somasundaram R, Sigvardsson M.

J Exp Med. 2015 Jun 29;212(7):1109-23. doi: 10.1084/jem.20132100. Epub 2015 Jun 8.

32.

Transcription factor networks in B-cell differentiation link development to acute lymphoid leukemia.

Somasundaram R, Prasad MA, Ungerbäck J, Sigvardsson M.

Blood. 2015 Jul 9;126(2):144-52. doi: 10.1182/blood-2014-12-575688. Epub 2015 May 19. Review.

33.

Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency.

Prasad MA, Ungerbäck J, Åhsberg J, Somasundaram R, Strid T, Larsson M, Månsson R, De Paepe A, Lilljebjörn H, Fioretos T, Hagman J, Sigvardsson M.

Blood. 2015 Jun 25;125(26):4052-9. doi: 10.1182/blood-2014-12-617282. Epub 2015 Apr 2.

34.

Sex differences of troponin test performance in chest pain patients.

Slagman A, Searle J, Vollert JO, Storchmann H, Büschenfelde DM, von Recum J, Vlasny D, Ale-Abaei A, Koch M, Müller C, Müller R, Somasundaram R, Möckel M.

Int J Cardiol. 2015;187:246-51. doi: 10.1016/j.ijcard.2015.03.261. Epub 2015 Mar 19.

PMID:
25838225
35.

A stress-induced early innate response causes multidrug tolerance in melanoma.

Menon DR, Das S, Krepler C, Vultur A, Rinner B, Schauer S, Kashofer K, Wagner K, Zhang G, Rad EB, Haass NK, Soyer HP, Gabrielli B, Somasundaram R, Hoefler G, Herlyn M, Schaider H.

Oncogene. 2015 Aug 20;34(34):4545. doi: 10.1038/onc.2014.432. Epub 2015 Jan 26.

PMID:
25619837
36.

Comparison of the source of introduction to cariogenic food substance and caries prevalence in children.

Somasundaram R, Rangeeth BN, Moses J, Sivakumar S.

J Clin Diagn Res. 2014 Nov;8(11):ZC138-40. doi: 10.7860/JCDR/2014/8967.5216. Epub 2014 Nov 20.

37.

Antimelanoma CTL recognizes peptides derived from an ORF transcribed from the antisense strand of the 3' untranslated region of TRIT1.

Swoboda RK, Somasundaram R, Caputo-Gross L, Marincola FM, Robbins P, Herlyn M, Herlyn D.

Mol Ther Oncolytics. 2015 Jan 14;1:14009. doi: 10.1038/mto.2014.9. eCollection 2015.

38.

A stress-induced early innate response causes multidrug tolerance in melanoma.

Ravindran Menon D, Das S, Krepler C, Vultur A, Rinner B, Schauer S, Kashofer K, Wagner K, Zhang G, Bonyadi Rad E, Haass NK, Soyer HP, Gabrielli B, Somasundaram R, Hoefler G, Herlyn M, Schaider H.

Oncogene. 2015 Aug 20;34(34):4448-59. doi: 10.1038/onc.2014.372. Epub 2014 Nov 24. Erratum in: Oncogene. 2015 Aug 20;34(34):4545.

39.

K⁺-channel inhibition reduces portal perfusion pressure in fibrotic rats and fibrosis associated characteristics of hepatic stellate cells.

Freise C, Heldwein S, Erben U, Hoyer J, Köhler R, Jöhrens K, Patsenker E, Ruehl M, Seehofer D, Stickel F, Somasundaram R.

Liver Int. 2015 Apr;35(4):1244-52. doi: 10.1111/liv.12681. Epub 2014 Sep 22.

PMID:
25212242
40.

Hepatitis C virus infection and kidney transplantation in 2014: what's new?

Baid-Agrawal S, Pascual M, Moradpour D, Somasundaram R, Muche M.

Am J Transplant. 2014 Oct;14(10):2206-20. doi: 10.1111/ajt.12835. Epub 2014 Aug 4. Review.

41.

Suppression of p21Rac signaling and increased innate immunity mediate remission in Crohn's disease.

Parikh K, Zhou L, Somasundaram R, Fuhler GM, Deuring JJ, Blokzijl T, Regeling A, Kuipers EJ, Weersma RK, Nuij VJ, Alves M, Vogelaar L, Visser L, de Haar C, Krishnadath KK, van der Woude CJ, Dijkstra G, Faber KN, Peppelenbosch MP.

Sci Transl Med. 2014 Apr 23;6(233):233ra53. doi: 10.1126/scitranslmed.3006763.

42.

Indomethacin to the rescue of TRAIL-resistant melanomas.

Somasundaram R, Herlyn M.

J Invest Dermatol. 2014 May;134(5):1198-1199. doi: 10.1038/jid.2014.1.

43.

Bone morphogenetic protein-12 induces tenogenic differentiation of mesenchymal stem cells derived from equine amniotic fluid.

Gulati BR, Kumar R, Mohanty N, Kumar P, Somasundaram RK, Yadav PS.

Cells Tissues Organs. 2013;198(5):377-89. doi: 10.1159/000358231. Epub 2014 Mar 21.

PMID:
24662023
44.

Wideband MRE and static mechanical indentation of human liver specimen: sensitivity of viscoelastic constants to the alteration of tissue structure in hepatic fibrosis.

Reiter R, Freise C, Jöhrens K, Kamphues C, Seehofer D, Stockmann M, Somasundaram R, Asbach P, Braun J, Samani A, Sack I.

J Biomech. 2014 May 7;47(7):1665-74. doi: 10.1016/j.jbiomech.2014.02.034. Epub 2014 Mar 5.

PMID:
24657103
45.

Meeting report from the 10th International Congress of the Society for Melanoma Research, Philadelphia, PA, November 2013.

Vultur A, O'Connell M, Webster M, Villanueva J, Herlyn D, Somasundaram R, Krepler C, Zaidi R, Patton E, Sekulic A, Jonsson G, Weeraratna AT.

Pigment Cell Melanoma Res. 2014 Jul;27(4):E1-E12. doi: 10.1111/pcmr.12240. Epub 2014 May 6. No abstract available.

46.

Immunophenotypic characterization and tenogenic differentiation of mesenchymal stromal cells isolated from equine umbilical cord blood.

Mohanty N, Gulati BR, Kumar R, Gera S, Kumar P, Somasundaram RK, Kumar S.

In Vitro Cell Dev Biol Anim. 2014 Jun;50(6):538-48. doi: 10.1007/s11626-013-9729-7. Epub 2014 Jan 11.

PMID:
24414976
47.

Peripheral neutrophil functions and cell signalling in Crohn`s disease.

Somasundaram R, Nuij VJ, van der Woude CJ, Kuipers EJ, Peppelenbosch MP, Fuhler GM.

PLoS One. 2013 Dec 19;8(12):e84521. doi: 10.1371/journal.pone.0084521. eCollection 2013.

48.

Isolation of melanoma cell subpopulations using negative selection.

Slipicevic A, Somasundaram R, Sproesser K, Herlyn M.

Methods Mol Biol. 2014;1102:501-12. doi: 10.1007/978-1-62703-727-3_26.

49.

SECTM1 produced by tumor cells attracts human monocytes via CD7-mediated activation of the PI3K pathway.

Wang T, Ge Y, Xiao M, Lopez-Coral A, Li L, Roesch A, Huang C, Alexander P, Vogt T, Xu X, Hwang WT, Lieu M, Belser E, Liu R, Somasundaram R, Herlyn M, Kaufman RE.

J Invest Dermatol. 2014 Apr;134(4):1108-1118. doi: 10.1038/jid.2013.437. Epub 2013 Oct 24.

50.

Comparative secretome analysis of epithelial and mesenchymal subpopulations of head and neck squamous cell carcinoma identifies S100A4 as a potential therapeutic target.

Rasanen K, Sriswasdi S, Valiga A, Tang HY, Zhang G, Perego M, Somasundaram R, Li L, Speicher K, Klein-Szanto AJ, Basu D, Rustgi AK, Speicher DW, Herlyn M.

Mol Cell Proteomics. 2013 Dec;12(12):3778-92. doi: 10.1074/mcp.M113.029587. Epub 2013 Sep 13.

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