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Cardet JC, Jiang X, Lu Q, Gerard N, McIntire K, Boushey HA, Castro M, Chinchilli VM, Codispoti CD, Dyer AM, Holguin F, Kraft M, Lazarus S, Lemanske RF, Lugogo N, Mauger D, Moore WC, Moy J, Ortega VE, Peters SP, Smith LJ, Solway J, Sorkness CA, Sumino K, Wechsler ME, Wenzel S, Israel E; AsthmaNet Investigators.

J Allergy Clin Immunol. 2019 Sep;144(3):873-874. doi: 10.1016/j.jaci.2019.05.029. Epub 2019 Jul 9. No abstract available.


Associations between fungal and bacterial microbiota of airways and asthma endotypes.

Sharma A, Laxman B, Naureckas ET, Hogarth DK, Sperling AI, Solway J, Ober C, Gilbert JA, White SR.

J Allergy Clin Immunol. 2019 Jul 3. pii: S0091-6749(19)30887-5. doi: 10.1016/j.jaci.2019.06.025. [Epub ahead of print]


Embedding research recruitment in a community resource e-prescribing system: lessons from an implementation study on Chicago's South Side.

Feldmeth G, Naureckas ET, Solway J, Lindau ST.

J Am Med Inform Assoc. 2019 Aug 1;26(8-9):840-846. doi: 10.1093/jamia/ocz059.


Evidence for an IL-6-high asthma phenotype in asthmatic patients of African ancestry.

White SR, Laxman B, Naureckas ET, Hogarth DK, Solway J, Sperling AI, Ober C.

J Allergy Clin Immunol. 2019 Jul;144(1):304-306.e4. doi: 10.1016/j.jaci.2019.04.007. Epub 2019 Apr 25. No abstract available.


Loss of bronchoprotection with ICS plus LABA treatment, β-receptor dynamics, and the effect of alendronate.

Cardet JC, Jiang X, Lu Q, Gerard N, McIntire K, Boushey HA, Castro M, Chinchilli VM, Codispoti CD, Dyer AM, Holguin F, Kraft M, Lazarus S, Lemanske RF, Lugogo N, Mauger D, Moore WC, Moy J, Ortega VE, Peters SP, Smith LJ, Solway J, Sorkness CA, Sumino K, Wechsler ME, Wenzel S, Israel E; AsthmaNet Investigators.

J Allergy Clin Immunol. 2019 Aug;144(2):416-425.e7. doi: 10.1016/j.jaci.2019.01.049. Epub 2019 Mar 11.


Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling.

Shigemura M, Lecuona E, Angulo M, Homma T, Rodríguez DA, Gonzalez-Gonzalez FJ, Welch LC, Amarelle L, Kim SJ, Kaminski N, Budinger GRS, Solway J, Sznajder JI.

Sci Transl Med. 2018 Sep 5;10(457). pii: eaat1662. doi: 10.1126/scitranslmed.aat1662.


Associations between environmental quality and adult asthma prevalence in medical claims data.

Gray CL, Lobdell DT, Rappazzo KM, Jian Y, Jagai JS, Messer LC, Patel AP, DeFlorio-Barker SA, Lyttle C, Solway J, Rzhetsky A.

Environ Res. 2018 Oct;166:529-536. doi: 10.1016/j.envres.2018.06.020. Epub 2018 Jun 27.


SM22 is required for the maintenance of actin-rich structures generated during bacterial infections.

Chua MD, Hipolito KJ, Singerr OB, Solway J, Guttman JA.

Exp Cell Res. 2018 Aug 1;369(1):139-146. doi: 10.1016/j.yexcr.2018.05.015. Epub 2018 May 18.


Preexisting Type 2 Immune Activation Protects against the Development of Sepsis.

Krishack PA, Wang K, Rzhetsky A, Solway J, Sperling AI, Verhoef PA.

Am J Respir Cell Mol Biol. 2017 Nov;57(5):628-630. doi: 10.1165/rcmb.2017-0277LE. No abstract available.


Elevated levels of soluble humanleukocyte antigen-G in the airways are a marker for a low-inflammatory endotype of asthma.

White SR, Nicodemus-Johnson J, Laxman B, Denner DR, Naureckas ET, Hogarth DK, Stern R, Minc A, Solway J, Sperling A, Ober C.

J Allergy Clin Immunol. 2017 Sep;140(3):857-860. doi: 10.1016/j.jaci.2017.02.031. Epub 2017 Mar 28. No abstract available.


DNA methylation in lung cells is associated with asthma endotypes and genetic risk.

Nicodemus-Johnson J, Myers RA, Sakabe NJ, Sobreira DR, Hogarth DK, Naureckas ET, Sperling AI, Solway J, White SR, Nobrega MA, Nicolae DL, Gilad Y, Ober C.

JCI Insight. 2016 Dec 8;1(20):e90151. doi: 10.1172/jci.insight.90151.


An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma.

An SS, Mitzner W, Tang WY, Ahn K, Yoon AR, Huang J, Kilic O, Yong HM, Fahey JW, Kumar S, Biswal S, Holgate ST, Panettieri RA Jr, Solway J, Liggett SB.

J Allergy Clin Immunol. 2016 Jul;138(1):294-297.e4. doi: 10.1016/j.jaci.2015.12.1315. Epub 2016 Feb 28. No abstract available.


Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways.

Denner DR, Sangwan N, Becker JB, Hogarth DK, Oldham J, Castillo J, Sperling AI, Solway J, Naureckas ET, Gilbert JA, White SR.

J Allergy Clin Immunol. 2016 May;137(5):1398-1405.e3. doi: 10.1016/j.jaci.2015.10.017. Epub 2015 Nov 25.


Chronic Activation of the Renin-Angiotensin System Induces Lung Fibrosis.

Wang J, Chen L, Chen B, Meliton A, Liu SQ, Shi Y, Liu T, Deb DK, Solway J, Li YC.

Sci Rep. 2015 Oct 23;5:15561. doi: 10.1038/srep15561.


Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways.

Nicodemus-Johnson J, Naughton KA, Sudi J, Hogarth K, Naurekas ET, Nicolae DL, Sperling AI, Solway J, White SR, Ober C.

Am J Respir Crit Care Med. 2016 Feb 15;193(4):376-85. doi: 10.1164/rccm.201506-1243OC.


Future Research Directions in Asthma. An NHLBI Working Group Report.

Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA Jr, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC.

Am J Respir Crit Care Med. 2015 Dec 1;192(11):1366-72. doi: 10.1164/rccm.201505-0963WS. Review.


High-throughput screening for modulators of cellular contractile force.

Park CY, Zhou EH, Tambe D, Chen B, Lavoie T, Dowell M, Simeonov A, Maloney DJ, Marinkovic A, Tschumperlin DJ, Burger S, Frykenberg M, Butler JP, Stamer WD, Johnson M, Solway J, Fredberg JJ, Krishnan R.

Integr Biol (Camb). 2015 Oct;7(10):1318-24. doi: 10.1039/c5ib00054h. Epub 2015 May 8.


Genome-wide interrogation of longitudinal FEV1 in children with asthma.

Wu K, Gamazon ER, Im HK, Geeleher P, White SR, Solway J, Clemmer GL, Weiss ST, Tantisira KG, Cox NJ, Ratain MJ, Huang RS.

Am J Respir Crit Care Med. 2014 Sep 15;190(6):619-27. doi: 10.1164/rccm.201403-0460OC.


MicroRNA-146a and microRNA-146b expression and anti-inflammatory function in human airway smooth muscle.

Comer BS, Camoretti-Mercado B, Kogut PC, Halayko AJ, Solway J, Gerthoffer WT.

Am J Physiol Lung Cell Mol Physiol. 2014 Nov 1;307(9):L727-34. doi: 10.1152/ajplung.00174.2014. Epub 2014 Sep 12.


Cyclooxygenase-2 and microRNA-155 expression are elevated in asthmatic airway smooth muscle cells.

Comer BS, Camoretti-Mercado B, Kogut PC, Halayko AJ, Solway J, Gerthoffer WT.

Am J Respir Cell Mol Biol. 2015 Apr;52(4):438-47. doi: 10.1165/rcmb.2014-0129OC.


A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes.

Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF Jr, Avila L, Soto-Quiros M, Barraza-Villareal A, Lemanske RF Jr, Solway J, Krishnan J, White SR, Cheadle C, Berger AE, Fan J, Boorgula MP, Nicolae D, Gilliland F, Barnes K, London SJ, Martinez F, Ober C, Celedón JC, Carey VJ, Weiss ST, Raby BA.

J Allergy Clin Immunol. 2014 Nov;134(5):1153-62. doi: 10.1016/j.jaci.2014.04.011. Epub 2014 Jun 13.


Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial.

Castro M, King TS, Kunselman SJ, Cabana MD, Denlinger L, Holguin F, Kazani SD, Moore WC, Moy J, Sorkness CA, Avila P, Bacharier LB, Bleecker E, Boushey HA, Chmiel J, Fitzpatrick AM, Gentile D, Hundal M, Israel E, Kraft M, Krishnan JA, LaForce C, Lazarus SC, Lemanske R, Lugogo N, Martin RJ, Mauger DT, Naureckas E, Peters SP, Phipatanakul W, Que LG, Sheshadri A, Smith L, Solway J, Sullivan-Vedder L, Sumino K, Wechsler ME, Wenzel S, White SR, Sutherland ER; National Heart, Lung, and Blood Institute’s AsthmaNet.

JAMA. 2014 May;311(20):2083-91. doi: 10.1001/jama.2014.5052.


Stiffness-activated GEF-H1 expression exacerbates LPS-induced lung inflammation.

Mambetsariev I, Tian Y, Wu T, Lavoie T, Solway J, Birukov KG, Birukova AA.

PLoS One. 2014 Apr 16;9(4):e92670. doi: 10.1371/journal.pone.0092670. eCollection 2014.


E3 ubiquitin ligase Cbl-b suppresses proallergic T cell development and allergic airway inflammation.

Qiao G, Ying H, Zhao Y, Liang Y, Guo H, Shen H, Li Z, Solway J, Tao E, Chiang YJ, Lipkowitz S, Penninger JM, Langdon WY, Zhang J.

Cell Rep. 2014 Feb 27;6(4):709-23. doi: 10.1016/j.celrep.2014.01.012. Epub 2014 Feb 6.


Airway contractility in the precision-cut lung slice after cryopreservation.

Rosner SR, Ram-Mohan S, Paez-Cortez JR, Lavoie TL, Dowell ML, Yuan L, Ai X, Fine A, Aird WC, Solway J, Fredberg JJ, Krishnan R.

Am J Respir Cell Mol Biol. 2014 May;50(5):876-81. doi: 10.1165/rcmb.2013-0166MA.


Airway smooth muscle: a potential target for asthma therapy.

Dowell ML, Lavoie TL, Solway J, Krishnan R.

Curr Opin Pulm Med. 2014 Jan;20(1):66-72. doi: 10.1097/MCP.0000000000000011. Review.


Gata5 deficiency causes airway constrictor hyperresponsiveness in mice.

Chen B, Moore TV, Li Z, Sperling AI, Zhang C, Andrade J, Rodriguez A, Bahroos N, Huang Y, Morrisey EE, Gruber PJ, Solway J.

Am J Respir Cell Mol Biol. 2014 Apr;50(4):787-95. doi: 10.1165/rcmb.2013-0294OC.


Emerging targets for novel therapy of asthma.

Gerthoffer WT, Solway J, Camoretti-Mercado B.

Curr Opin Pharmacol. 2013 Jun;13(3):324-30. doi: 10.1016/j.coph.2013.04.002. Epub 2013 Apr 29. Review.


The sharing partnership for innovative research in translation (SPIRiT) consortium: a model for collaboration across CTSA sites.

Reis SE, Patterson PD, Fitzgerald GA, Ford D, Sherwin RS, Solway J, Evanoff BA.

Clin Transl Sci. 2013 Apr;6(2):85-7. doi: 10.1111/cts.12039. No abstract available.


Maternal asthma and microRNA regulation of soluble HLA-G in the airway.

Nicodemus-Johnson J, Laxman B, Stern RK, Sudi J, Tierney CN, Norwick L, Hogarth DK, McConville JF, Naureckas ET, Sperling AI, Solway J, Krishnan JA, Nicolae DL, White SR, Ober C.

J Allergy Clin Immunol. 2013 Jun;131(6):1496-503. doi: 10.1016/j.jaci.2013.01.037. Epub 2013 Mar 25.


Airway smooth muscle in the pathophysiology and treatment of asthma.

Doeing DC, Solway J.

J Appl Physiol (1985). 2013 Apr;114(7):834-43. doi: 10.1152/japplphysiol.00950.2012. Epub 2013 Jan 10. Review.


miR-140-3p regulation of TNF-α-induced CD38 expression in human airway smooth muscle cells.

Jude JA, Dileepan M, Subramanian S, Solway J, Panettieri RA Jr, Walseth TF, Kannan MS.

Am J Physiol Lung Cell Mol Physiol. 2012 Sep;303(5):L460-8. doi: 10.1152/ajplung.00041.2012. Epub 2012 Jul 6.


Dilatation of the constricted human airway by tidal expansion of lung parenchyma.

Lavoie TL, Krishnan R, Siegel HR, Maston ED, Fredberg JJ, Solway J, Dowell ML.

Am J Respir Crit Care Med. 2012 Aug 1;186(3):225-32. doi: 10.1164/rccm.201202-0368OC. Epub 2012 Jun 7.


Genomic medicine and lung diseases.

Center DM, Schwartz DA, Solway J, Gail D, Laposky AD, Lin QS, Gan W.

Am J Respir Crit Care Med. 2012 Aug 1;186(3):280-5. doi: 10.1164/rccm.201203-0569WS. Epub 2012 May 31. Review.


Upstream stimulatory factor 1 activates GATA5 expression through an E-box motif.

Chen B, Hsu R, Li Z, Kogut PC, Du Q, Rouser K, Camoretti-Mercado B, Solway J.

Biochem J. 2012 Aug 15;446(1):89-98. doi: 10.1042/BJ20111942.


Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS).

CTSA Principal Investigators, Shamoon H, Center D, Davis P, Tuchman M, Ginsberg H, Califf R, Stephens D, Mellman T, Verbalis J, Nadler L, Shekhar A, Ford D, Rizza R, Shaker R, Brady K, Murphy B, Cronstein B, Hochman J, Greenland P, Orwoll E, Sinoway L, Greenberg H, Jackson R, Coller B, Topol E, Guay-Woodford L, Runge M, Clark R, McClain D, Selker H, Lowery C, Dubinett S, Berglund L, Cooper D, Firestein G, Johnston SC, Solway J, Heubi J, Sokol R, Nelson D, Tobacman L, Rosenthal G, Aaronson L, Barohn R, Kern P, Sullivan J, Shanley T, Blazar B, Larson R, FitzGerald G, Reis S, Pearson T, Buchanan T, McPherson D, Brasier A, Toto R, Disis M, Drezner M, Bernard G, Clore J, Evanoff B, Imperato-McGinley J, Sherwin R, Pulley J.

Clin Transl Sci. 2012 Apr;5(2):121-9. doi: 10.1111/j.1752-8062.2012.00401.x. Epub 2012 Mar 27.


Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice.

Ferreira CM, Chen JL, Li J, Shimomura K, Yang X, Lussier YA, Pinto LH, Solway J.

PLoS One. 2012;7(1):e29579. doi: 10.1371/journal.pone.0029579. Epub 2012 Jan 10.


Kv7 potassium channels in airway smooth muscle cells: signal transduction intermediates and pharmacological targets for bronchodilator therapy.

Brueggemann LI, Kakad PP, Love RB, Solway J, Dowell ML, Cribbs LL, Byron KL.

Am J Physiol Lung Cell Mol Physiol. 2012 Jan 1;302(1):L120-32. doi: 10.1152/ajplung.00194.2011. Epub 2011 Sep 30.


Akt activation induces hypertrophy without contractile phenotypic maturation in airway smooth muscle.

Ma L, Brown M, Kogut P, Serban K, Li X, McConville J, Chen B, Bentley JK, Hershenson MB, Dulin N, Solway J, Camoretti-Mercado B.

Am J Physiol Lung Cell Mol Physiol. 2011 May;300(5):L701-9. doi: 10.1152/ajplung.00119.2009. Epub 2011 Mar 4.


Mechanical and structural plasticity.

Seow CY, Solway J.

Compr Physiol. 2011 Jan;1(1):283-93. doi: 10.1002/cphy.c100024. Review.


Nuclear import of serum response factor in airway smooth muscle.

McConville JF, Fernandes DJ, Churchill J, Dewundara S, Kogut P, Shah S, Fuchs G, Kedainis D, Bellam SK, Patel NM, McCauley J, Dulin NO, Gupta MP, Adam S, Yoneda Y, Camoretti-Mercado B, Solway J.

Am J Respir Cell Mol Biol. 2011 Sep;45(3):453-8. doi: 10.1165/rcmb.2008-0393OC. Epub 2010 Dec 3.


Differential induction of CD38 expression by TNF-{alpha} in asthmatic airway smooth muscle cells.

Jude JA, Solway J, Panettieri RA Jr, Walseth TF, Kannan MS.

Am J Physiol Lung Cell Mol Physiol. 2010 Dec;299(6):L879-90. doi: 10.1152/ajplung.00021.2010. Epub 2010 Aug 6.


The University of Chicago Institute for Translational Medicine.

Solway J, Rehman B, Ross LF.

Clin Transl Sci. 2009 Dec;2(6):394-7. doi: 10.1111/j.1752-8062.2009.00150.x. No abstract available.


MEK modulates force-fluctuation-induced relengthening of canine tracheal smooth muscle.

Dowell ML, Lavoie TL, Lakser OJ, Dulin NO, Fredberg JJ, Gerthoffer WT, Seow CY, Mitchell RW, Solway J.

Eur Respir J. 2010 Sep;36(3):630-7. doi: 10.1183/09031936.00160209. Epub 2010 Jan 28.


Angiotensin I-converting enzyme mutation (Trp1197Stop) causes a dramatic increase in blood ACE.

Nesterovitch AB, Hogarth KD, Adarichev VA, Vinokour EI, Schwartz DE, Solway J, Danilov SM.

PLoS One. 2009 Dec 14;4(12):e8282. doi: 10.1371/journal.pone.0008282.


Alternative promoter and GATA5 transcripts in mouse.

Chen B, Yates E, Huang Y, Kogut P, Ma L, Turner JR, Tao Y, Camoretti-Mercado B, Lang D, Svensson EC, Garcia JG, Gruber PJ, Morrisey EE, Solway J.

Am J Physiol Gastrointest Liver Physiol. 2009 Dec;297(6):G1214-22. doi: 10.1152/ajpgi.00165.2009. Epub 2009 Sep 24.


p70 Ribosomal S6 kinase is required for airway smooth muscle cell size enlargement but not increased contractile protein expression.

Deng H, Hershenson MB, Lei J, Bitar KN, Fingar DC, Solway J, Bentley JK.

Am J Respir Cell Mol Biol. 2010 Jun;42(6):744-52. doi: 10.1165/rcmb.2009-0037OC. Epub 2009 Jul 31.


Lysophosphatidic acid enhances pulmonary epithelial barrier integrity and protects endotoxin-induced epithelial barrier disruption and lung injury.

He D, Su Y, Usatyuk PV, Spannhake EW, Kogut P, Solway J, Natarajan V, Zhao Y.

J Biol Chem. 2009 Sep 4;284(36):24123-32. doi: 10.1074/jbc.M109.007393. Epub 2009 Jul 8.


Disrupting actin-myosin-actin connectivity in airway smooth muscle as a treatment for asthma?

Lavoie TL, Dowell ML, Lakser OJ, Gerthoffer WT, Fredberg JJ, Seow CY, Mitchell RW, Solway J.

Proc Am Thorac Soc. 2009 May 1;6(3):295-300. doi: 10.1513/pats.200808-078RM. Review.


Myosin, transgelin, and myosin light chain kinase: expression and function in asthma.

Léguillette R, Laviolette M, Bergeron C, Zitouni N, Kogut P, Solway J, Kachmar L, Hamid Q, Lauzon AM.

Am J Respir Crit Care Med. 2009 Feb 1;179(3):194-204. doi: 10.1164/rccm.200609-1367OC. Epub 2008 Nov 14.

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