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Items: 24

1.

SCY-078, a Novel Fungicidal Agent, Demonstrates Distribution to Tissues Associated with Fungal Infections during Mass Balance Studies with Intravenous and Oral [14C]SCY-078 in Albino and Pigmented Rats.

Wring S, Borroto-Esoda K, Solon E, Angulo D.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e02119-18. doi: 10.1128/AAC.02119-18. Print 2019 Feb.

PMID:
30478166
2.

Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo.

Ma J, Zhang X, Soloveva V, Warren T, Guo F, Wu S, Lu H, Guo J, Su Q, Shen H, Solon E, Comunale MA, Mehta A, Guo JT, Bavari S, Du Y, Block TM, Chang J.

Antiviral Res. 2018 Feb;150:112-122. doi: 10.1016/j.antiviral.2017.12.008. Epub 2017 Dec 15.

3.

Pharmacokinetics, distribution, metabolism, and excretion of the dual reuptake inhibitor [(14)C]-nefopam in rats.

Yu J, Solon E, Shen H, Modi NB, Mittur A.

Xenobiotica. 2016 Nov;46(11):1026-48. doi: 10.3109/00498254.2016.1145755. Epub 2016 Feb 29.

PMID:
26927982
4.

Autoradiography techniques and quantification of drug distribution.

Solon EG.

Cell Tissue Res. 2015 Apr;360(1):87-107. doi: 10.1007/s00441-014-2093-4. Epub 2015 Jan 22. Review.

PMID:
25604842
5.

Peginesatide clearance, distribution, metabolism, and excretion in monkeys following intravenous administration.

Woodburn KW, Fong KL, Wilson SD, Sloneker S, Strzemienski P, Solon E, Moriya Y, Tagawa Y.

Drug Metab Dispos. 2013 Apr;41(4):774-84. doi: 10.1124/dmd.112.048033. Epub 2013 Jan 14.

PMID:
23318685
6.

Evaluation of metabolism and disposition of GDC-0152 in rats using 14C labeling strategy at two different positions: a novel formation of hippuric acid from 4-phenyl-5-amino-1,2,3-thiadiazole.

Yue Q, Mulder T, Rudewicz PJ, Solon E, Budha N, Ware JA, Lyssikatos J, Hop CE, Wong H, Khojasteh SC.

Drug Metab Dispos. 2013 Feb;41(2):508-17. doi: 10.1124/dmd.112.047019. Epub 2012 Dec 4.

PMID:
23223496
7.

Use of radioactive compounds and autoradiography to determine drug tissue distribution.

Solon EG.

Chem Res Toxicol. 2012 Mar 19;25(3):543-55. doi: 10.1021/tx200509f. Epub 2012 Feb 9. Review.

PMID:
22280496
8.

Absorption, distribution, metabolism, and excretion of [¹⁴C]GDC-0449 (vismodegib), an orally active hedgehog pathway inhibitor, in rats and dogs: a unique metabolic pathway via pyridine ring opening.

Yue Q, Chen YH, Mulder T, Deese A, Takahashi R, Rudewicz PJ, Reynolds M, Solon E, Hop CE, Wong H, Khojasteh SC.

Drug Metab Dispos. 2011 Jun;39(6):952-65. doi: 10.1124/dmd.110.037374. Epub 2011 Mar 1.

PMID:
21363998
9.

Skin distribution of imidacloprid by microautoradiography after topical administration to beagle dogs.

Chopade H, Eigenberg D, Solon E, Strzemienski P, Hostetler J, McNamara T.

Vet Ther. 2010 Winter;11(4):E1-10.

PMID:
21308663
10.

Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development.

Solon EG, Schweitzer A, Stoeckli M, Prideaux B.

AAPS J. 2010 Mar;12(1):11-26. doi: 10.1208/s12248-009-9158-4. Epub 2009 Nov 17. Review. Erratum in: AAPS J. 2010 Mar;12(1):107.

11.

Role of P-glycoprotein and the intestine in the excretion of DPC 333 [(2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in rodents.

Garner CE, Solon E, Lai CM, Lin J, Luo G, Jones K, Duan J, Decicco CP, Maduskuie T, Mercer SE, Gan LS, Qian M, Prakash S, Shen HS, Lee FW.

Drug Metab Dispos. 2008 Jun;36(6):1102-10. doi: 10.1124/dmd.107.017038. Epub 2008 Mar 17.

PMID:
18347085
12.

Distribution of radioactivity in bone and related structures following administration of [14C]dalbavancin to New Zealand white rabbits.

Solon EG, Dowell JA, Lee J, King SP, Damle BD.

Antimicrob Agents Chemother. 2007 Aug;51(8):3008-10. Epub 2007 Jun 4.

13.

Autoradiography: high-resolution molecular imaging in pharmaceutical discovery and development.

Solon EG.

Expert Opin Drug Discov. 2007 Apr;2(4):503-14. doi: 10.1517/17460441.2.4.503.

PMID:
23484758
14.

Increased hepatobiliary clearance of unconjugated thyroxine determines DMP 904-induced alterations in thyroid hormone homeostasis in rats.

Wong H, Lehman-McKeeman LD, Grubb MF, Grossman SJ, Bhaskaran VM, Solon EG, Shen HS, Gerson RJ, Car BD, Zhao B, Gemzik B.

Toxicol Sci. 2005 Apr;84(2):232-42. Epub 2005 Jan 26.

PMID:
15673846
15.

Radiation dose to abdominal organs of the mouse due to 90Y in the urinary bladder.

Lazewatsky J, Ding Y, Onthank D, Silva P, Solon E, Robinson S.

Cancer Biother Radiopharm. 2003 Jun;18(3):413-9.

PMID:
12954127
16.

Concurrent induction and mechanism-based inactivation of CYP3A4 by an L-valinamide derivative.

Luo G, Lin J, Fiske WD, Dai R, Yang TJ, Kim S, Sinz M, LeCluyse E, Solon E, Brennan JM, Benedek IH, Jolley S, Gilbert D, Wang L, Lee FW, Gan LS.

Drug Metab Dispos. 2003 Sep;31(9):1170-5.

PMID:
12920173
18.
19.

Interaction of ritonavir on tissue distribution of a [(14)c]L-valinamide, a potent human immunodeficiency virus-1 protease inhibitor, in rats using quantitative whole-body autoradiography.

Solon EG, Balani SK, Luo G, Yang TJ, Haines PJ, Wang L, Demond T, Diamond S, Christ DD, Gan LS, Lee FW.

Drug Metab Dispos. 2002 Nov;30(11):1164-9.

PMID:
12386120
20.

Whole-body autoradiography in drug discovery.

Solon EG, Balani SK, Lee FW.

Curr Drug Metab. 2002 Oct;3(5):451-62. Review.

PMID:
12369892
21.

Localization of a putative inositol 1,4,5-triphosphate receptor in the Limulus granulocyte.

Solon E, Gupta AP, Gaugler R.

Dev Comp Immunol. 1997 May-Jun;21(3):277-85.

PMID:
9258609
22.

Risperidone-reserpine combination in refractory psychosis.

Solon EN.

Schizophr Res. 1996 Dec 15;22(3):265-6. No abstract available.

PMID:
9000324
23.

Signal transduction during exocytosis in Limulus polyphemus granulocytes.

Solon E, Gupta AP, Gaugler R.

Dev Comp Immunol. 1996 Sep-Oct;20(5):307-21.

PMID:
9016385
24.

The electrical double layer with simultaneous anion and cation specific adsorption: thallium(I) nitrate.

Susbielles GG, Delahay P, Solon E.

J Phys Chem. 1966 Aug;70(8):2601-8. No abstract available.

PMID:
5920354

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