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Items: 43


Candidalysin Is Required for Neutrophil Recruitment and Virulence During Systemic Candida albicans Infection.

Swidergall M, Khalaji M, Solis NV, Moyes DL, Drummond RA, Hube B, Lionakis MS, Murdoch C, Filler SG, Naglik JR.

J Infect Dis. 2019 Sep 26;220(9):1477-1488. doi: 10.1093/infdis/jiz322.


EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection.

Swidergall M, Solis NV, Wang Z, Phan QT, Marshall ME, Lionakis MS, Pearlman E, Filler SG.

Cell Rep. 2019 Jul 9;28(2):423-433.e5. doi: 10.1016/j.celrep.2019.06.020.


Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype.

Forche A, Solis NV, Swidergall M, Thomas R, Guyer A, Beach A, Cromie GA, Le GT, Lowell E, Pavelka N, Berman J, Dudley AM, Selmecki A, Filler SG.

PLoS Genet. 2019 May 15;15(5):e1008137. doi: 10.1371/journal.pgen.1008137. eCollection 2019 May.


Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity.

Liu H, Xu W, Solis NV, Woolford C, Mitchell AP, Filler SG.

Virulence. 2018;9(1):1062-1073. doi: 10.1080/21505594.2018.1482182.


Author Correction: EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans.

Swidergall M, Solis NV, Lionakis MS, Filler SG.

Nat Microbiol. 2018 Sep;3(9):1074. doi: 10.1038/s41564-018-0188-5.


Candida albicans Cannot Acquire Sufficient Ethanolamine from the Host To Support Virulence in the Absence of De Novo Phosphatidylethanolamine Synthesis.

Davis SE, Tams RN, Solis NV, Wagner AS, Chen T, Jackson JW, Hasim S, Montedonico AE, Dinsmore J, Sparer TE, Filler SG, Reynolds TB.

Infect Immun. 2018 Jul 23;86(8). pii: e00815-17. doi: 10.1128/IAI.00815-17. Print 2018 Aug.


Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans.

Forche A, Cromie G, Gerstein AC, Solis NV, Pisithkul T, Srifa W, Jeffery E, Abbey D, Filler SG, Dudley AM, Berman J.

Genetics. 2018 Jul;209(3):725-741. doi: 10.1534/genetics.118.301019. Epub 2018 May 3.


Candida albicans White-Opaque Switching Influences Virulence but Not Mating during Oropharyngeal Candidiasis.

Solis NV, Park YN, Swidergall M, Daniels KJ, Filler SG, Soll DR.

Infect Immun. 2018 May 22;86(6). pii: e00774-17. doi: 10.1128/IAI.00774-17. Print 2018 Jun.


Publisher Correction: EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans.

Swidergall M, Solis NV, Lionakis MS, Filler SG.

Nat Microbiol. 2018 Mar;3(3):387. doi: 10.1038/s41564-017-0100-8.


Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy.

McLellan CA, Vincent BM, Solis NV, Lancaster AK, Sullivan LB, Hartland CL, Youngsaye W, Filler SG, Whitesell L, Lindquist S.

Nat Chem Biol. 2018 Feb;14(2):135-141. doi: 10.1038/nchembio.2534. Epub 2017 Dec 11.


EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans.

Swidergall M, Solis NV, Lionakis MS, Filler SG.

Nat Microbiol. 2018 Jan;3(1):53-61. doi: 10.1038/s41564-017-0059-5. Epub 2017 Nov 13. Erratum in: Nat Microbiol. 2018 Feb 13;:. Nat Microbiol. 2018 Sep;3(9):1074.


The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis.

Solis NV, Swidergall M, Bruno VM, Gaffen SL, Filler SG.

mBio. 2017 Mar 21;8(2). pii: e00025-17. doi: 10.1128/mBio.00025-17.


Role of Arf GTPases in fungal morphogenesis and virulence.

Labbaoui H, Bogliolo S, Ghugtyal V, Solis NV, Filler SG, Arkowitz RA, Bassilana M.

PLoS Pathog. 2017 Feb 13;13(2):e1006205. doi: 10.1371/journal.ppat.1006205. eCollection 2017 Feb.


Innate Immune Memory Contributes to Host Defense against Recurrent Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus.

Chan LC, Chaili S, Filler SG, Miller LS, Solis NV, Wang H, Johnson CW, Lee HK, Diaz LF, Yeaman MR.

Infect Immun. 2017 Jan 26;85(2). pii: e00876-16. doi: 10.1128/IAI.00876-16. Print 2017 Feb.


Aspergillus fumigatus CalA binds to integrin α5β1 and mediates host cell invasion.

Liu H, Lee MJ, Solis NV, Phan QT, Swidergall M, Ralph B, Ibrahim AS, Sheppard DC, Filler SG.

Nat Microbiol. 2016 Nov 14;2:16211. doi: 10.1038/nmicrobiol.2016.211.


Gene Expression Profiling of Infecting Microbes Using a Digital Bar-coding Platform.

Xu W, Solis NV, Filler SG, Mitchell AP.

J Vis Exp. 2016 Jan 13;(107):e53460. doi: 10.3791/53460.


The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps.

Lee MJ, Liu H, Barker BM, Snarr BD, Gravelat FN, Al Abdallah Q, Gavino C, Baistrocchi SR, Ostapska H, Xiao T, Ralph B, Solis NV, Lehoux M, Baptista SD, Thammahong A, Cerone RP, Kaminskyj SG, Guiot MC, Latgé JP, Fontaine T, Vinh DC, Filler SG, Sheppard DC.

PLoS Pathog. 2015 Oct 22;11(10):e1005187. doi: 10.1371/journal.ppat.1005187. eCollection 2015 Oct.


Pathogen Gene Expression Profiling During Infection Using a Nanostring nCounter Platform.

Xu W, Solis NV, Filler SG, Mitchell AP.

Methods Mol Biol. 2016;1361:57-65. doi: 10.1007/978-1-4939-3079-1_3.


Candida albicans cell shaving uncovers new proteins involved in cell wall integrity, yeast to hypha transition, stress response and host-pathogen interaction.

Gil-Bona A, Parra-Giraldo CM, Hernáez ML, Reales-Calderon JA, Solis NV, Filler SG, Monteoliva L, Gil C.

J Proteomics. 2015 Sep 8;127(Pt B):340-351. doi: 10.1016/j.jprot.2015.06.006. Epub 2015 Jun 15.


Activation and alliance of regulatory pathways in C. albicans during mammalian infection.

Xu W, Solis NV, Ehrlich RL, Woolford CA, Filler SG, Mitchell AP.

PLoS Biol. 2015 Feb 18;13(2):e1002076. doi: 10.1371/journal.pbio.1002076. eCollection 2015 Feb.


Using Bayesian modelling to investigate factors governing antibiotic-induced Candida albicans colonization of the GI tract.

Shankar J, Solis NV, Mounaud S, Szpakowski S, Liu H, Losada L, Nierman WC, Filler SG.

Sci Rep. 2015 Feb 3;5:8131. doi: 10.1038/srep08131.


A systematic evaluation of high-dimensional, ensemble-based regression for exploring large model spaces in microbiome analyses.

Shankar J, Szpakowski S, Solis NV, Mounaud S, Liu H, Losada L, Nierman WC, Filler SG.

BMC Bioinformatics. 2015 Feb 1;16:31. doi: 10.1186/s12859-015-0467-6.


CX3CR1 is dispensable for control of mucosal Candida albicans infections in mice and humans.

Break TJ, Jaeger M, Solis NV, Filler SG, Rodriguez CA, Lim JK, Lee CC, Sobel JD, Netea MG, Lionakis MS.

Infect Immun. 2015 Mar;83(3):958-65. doi: 10.1128/IAI.02604-14. Epub 2014 Dec 29.


Different tumor necrosis factor α antagonists have different effects on host susceptibility to disseminated and oropharyngeal candidiasis in mice.

Park H, Solis NV, Louie JS, Spellberg B, Rodriguez N, Filler SG.

Virulence. 2014 Jul 1;5(5):625-9. doi: 10.4161/viru.29699. Epub 2014 Jul 9.


Role of retrograde trafficking in stress response, host cell interactions, and virulence of Candida albicans.

Liu Y, Solis NV, Heilmann CJ, Phan QT, Mitchell AP, Klis FM, Filler SG.

Eukaryot Cell. 2014 Feb;13(2):279-87. doi: 10.1128/EC.00295-13. Epub 2013 Dec 20.


Synergistic regulation of hyphal elongation by hypoxia, CO(2), and nutrient conditions controls the virulence of Candida albicans.

Lu Y, Su C, Solis NV, Filler SG, Liu H.

Cell Host Microbe. 2013 Nov 13;14(5):499-509. doi: 10.1016/j.chom.2013.10.008.


Glycerophosphocholine utilization by Candida albicans: role of the Git3 transporter in virulence.

Bishop AC, Ganguly S, Solis NV, Cooley BM, Jensen-Seaman MI, Filler SG, Mitchell AP, Patton-Vogt J.

J Biol Chem. 2013 Nov 22;288(47):33939-52. doi: 10.1074/jbc.M113.505735. Epub 2013 Oct 10.


Candida albicans CUG mistranslation is a mechanism to create cell surface variation.

Miranda I, Silva-Dias A, Rocha R, Teixeira-Santos R, Coelho C, Gonçalves T, Santos MA, Pina-Vaz C, Solis NV, Filler SG, Rodrigues AG.

mBio. 2013 Aug 30;4(4). pii: e00285-13. doi: 10.1128/mBio.00285-13.


Investigation of the function of Candida albicans Als3 by heterologous expression in Candida glabrata.

Fu Y, Phan QT, Luo G, Solis NV, Liu Y, Cormack BP, Edwards JE Jr, Ibrahim AS, Filler SG.

Infect Immun. 2013 Jul;81(7):2528-35. doi: 10.1128/IAI.00013-13. Epub 2013 Apr 29.


SR-like RNA-binding protein Slr1 affects Candida albicans filamentation and virulence.

Ariyachet C, Solis NV, Liu Y, Prasadarao NV, Filler SG, McBride AE.

Infect Immun. 2013 Apr;81(4):1267-76. doi: 10.1128/IAI.00864-12. Epub 2013 Feb 4.


Bcr1 functions downstream of Ssd1 to mediate antimicrobial peptide resistance in Candida albicans.

Jung SI, Finkel JS, Solis NV, Chaili S, Mitchell AP, Yeaman MR, Filler SG.

Eukaryot Cell. 2013 Mar;12(3):411-9. doi: 10.1128/EC.00285-12. Epub 2013 Jan 11.


EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection.

Zhu W, Phan QT, Boontheung P, Solis NV, Loo JA, Filler SG.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14194-9. doi: 10.1073/pnas.1117676109. Epub 2012 Aug 13.


Divergent responses of different endothelial cell types to infection with Candida albicans and Staphylococcus aureus.

Seidl K, Solis NV, Bayer AS, Hady WA, Ellison S, Klashman MC, Xiong YQ, Filler SG.

PLoS One. 2012;7(6):e39633. doi: 10.1371/journal.pone.0039633. Epub 2012 Jun 22.


Mouse model of oropharyngeal candidiasis.

Solis NV, Filler SG.

Nat Protoc. 2012 Mar 8;7(4):637-42. doi: 10.1038/nprot.2012.011.


Mechanisms of Candida albicans trafficking to the brain.

Liu Y, Mittal R, Solis NV, Prasadarao NV, Filler SG.

PLoS Pathog. 2011 Oct;7(10):e1002305. doi: 10.1371/journal.ppat.1002305. Epub 2011 Oct 6.


Concentration of antifungal agents within host cell membranes: a new paradigm governing the efficacy of prophylaxis.

Campoli P, Al Abdallah Q, Robitaille R, Solis NV, Fielhaber JA, Kristof AS, Laverdiere M, Filler SG, Sheppard DC.

Antimicrob Agents Chemother. 2011 Dec;55(12):5732-9. doi: 10.1128/AAC.00637-11. Epub 2011 Sep 19.


Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection.

Peltz G, Zaas AK, Zheng M, Solis NV, Zhang MX, Liu HH, Hu Y, Boxx GM, Phan QT, Dill D, Filler SG.

Infect Immun. 2011 Nov;79(11):4472-9. doi: 10.1128/IAI.05666-11. Epub 2011 Aug 29.


Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis.

Chen YL, Brand A, Morrison EL, Silao FG, Bigol UG, Malbas FF Jr, Nett JE, Andes DR, Solis NV, Filler SG, Averette A, Heitman J.

Eukaryot Cell. 2011 Jun;10(6):803-19. doi: 10.1128/EC.00310-10. Epub 2011 Apr 29.


Host cell invasion and virulence mediated by Candida albicans Ssa1.

Sun JN, Solis NV, Phan QT, Bajwa JS, Kashleva H, Thompson A, Liu Y, Dongari-Bagtzoglou A, Edgerton M, Filler SG.

PLoS Pathog. 2010 Nov 11;6(11):e1001181. doi: 10.1371/journal.ppat.1001181.


Role of Aspergillus fumigatus DvrA in host cell interactions and virulence.

Ejzykowicz DE, Solis NV, Gravelat FN, Chabot J, Li X, Sheppard DC, Filler SG.

Eukaryot Cell. 2010 Oct;9(10):1432-40. doi: 10.1128/EC.00055-10. Epub 2010 Jul 30.


An RNA transport system in Candida albicans regulates hyphal morphology and invasive growth.

Elson SL, Noble SM, Solis NV, Filler SG, Johnson AD.

PLoS Genet. 2009 Sep;5(9):e1000664. doi: 10.1371/journal.pgen.1000664. Epub 2009 Sep 25. Erratum in: PLoS Genet. 2009 Oct;5(10). doi: 10.1371/annotation/17eb3a67-8f49-454b-acbf-5ff2872c27ff.


The Aspergillus fumigatus transcription factor Ace2 governs pigment production, conidiation and virulence.

Ejzykowicz DE, Cunha MM, Rozental S, Solis NV, Gravelat FN, Sheppard DC, Filler SG.

Mol Microbiol. 2009 Apr;72(1):155-69. doi: 10.1111/j.1365-2958.2009.06631.x. Epub 2009 Feb 11.


Pharmacokinetics of murine p75-Fc fusion protein and MP6-XT22 anti-murine TNF-alpha mAb in mice.

Filler SG, Solis NV, Guo J, Doellgast G, Ruiz-Garcia A, Pan WJ.

J Investig Dermatol Symp Proc. 2007 May;12(1):52-6.

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