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Items: 36


Clathrin switches Transforming Growth Factor-β role to pro-tumorigenic in liver cancer.

Caballero-Díaz D, Bertran E, Peñuelas-Haro I, Moreno-Càceres J, Malfettone A, López-Luque J, Addante A, Herrera B, Sánchez A, Alay A, Solé X, Serrano T, Ramos E, Fabregat I.

J Hepatol. 2019 Sep 25. pii: S0168-8278(19)30549-5. doi: 10.1016/j.jhep.2019.09.012. [Epub ahead of print]


AKT1low quiescent cancer cells in ductal carcinoma in situ of the breast.

Kabraji S, Sole X, Huang Y, Bango C, Sgroi D, Loda M, Ramaswamy S.

NPJ Breast Cancer. 2019 Mar 21;5:10. doi: 10.1038/s41523-019-0105-y. eCollection 2019.


Colon-specific eQTL analysis to inform on functional SNPs.

Moreno V, Alonso MH, Closa A, Vallés X, Diez-Villanueva A, Valle L, Castellví-Bel S, Sanz-Pamplona R, Lopez-Doriga A, Cordero D, Solé X.

Br J Cancer. 2018 Oct;119(8):971-977. doi: 10.1038/s41416-018-0018-9. Epub 2018 Oct 4.


AKT1low Quiescent Cancer Cells Promote Solid Tumor Growth.

Alves CP, Dey-Guha I, Kabraji S, Yeh AC, Talele NP, Solé X, Chowdhury J, Mino-Kenudson M, Loda M, Sgroi D, Borresen-Dale AL, Russnes HG, Ross KN, Ramaswamy S.

Mol Cancer Ther. 2018 Jan;17(1):254-263. doi: 10.1158/1535-7163.MCT-16-0868. Epub 2017 Oct 20.


AKT1low quiescent cancer cells persist after neoadjuvant chemotherapy in triple negative breast cancer.

Kabraji S, Solé X, Huang Y, Bango C, Bowden M, Bardia A, Sgroi D, Loda M, Ramaswamy S.

Breast Cancer Res. 2017 Aug 1;19(1):88. doi: 10.1186/s13058-017-0877-7.


Comprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component.

Alonso MH, Aussó S, Lopez-Doriga A, Cordero D, Guinó E, Solé X, Barenys M, de Oca J, Capella G, Salazar R, Sanz-Pamplona R, Moreno V.

Br J Cancer. 2017 Jul 25;117(3):421-431. doi: 10.1038/bjc.2017.208. Epub 2017 Jul 6.


Integrin β1 activation induces an anti-melanoma host response.

Ritsma L, Dey-Guha I, Talele N, Sole X, Salony, Chowdhury J, Ross KN, Ramaswamy S.

PLoS One. 2017 Apr 27;12(4):e0175300. doi: 10.1371/journal.pone.0175300. eCollection 2017.


JARID1B Enables Transit between Distinct States of the Stem-like Cell Population in Oral Cancers.

Facompre ND, Harmeyer KM, Sole X, Kabraji S, Belden Z, Sahu V, Whelan K, Tanaka K, Weinstein GS, Montone KT, Roesch A, Gimotty PA, Herlyn M, Rustgi AK, Nakagawa H, Ramaswamy S, Basu D.

Cancer Res. 2016 Sep 15;76(18):5538-49. doi: 10.1158/0008-5472.CAN-15-3377. Epub 2016 Aug 3. Erratum in: Cancer Res. 2017 Dec 15;77(24):7136.


AKT Inhibition Promotes Nonautonomous Cancer Cell Survival.

Salony, Solé X, Alves CP, Dey-Guha I, Ritsma L, Boukhali M, Lee JH, Chowdhury J, Ross KN, Haas W, Vasudevan S, Ramaswamy S.

Mol Cancer Ther. 2016 Jan;15(1):142-53. doi: 10.1158/1535-7163.MCT-15-0414. Epub 2015 Dec 4.


A mechanism for asymmetric cell division resulting in proliferative asynchronicity.

Dey-Guha I, Alves CP, Yeh AC, Salony, Sole X, Darp R, Ramaswamy S.

Mol Cancer Res. 2015 Feb;13(2):223-30. doi: 10.1158/1541-7786.MCR-14-0474. Epub 2015 Jan 12.


Large differences in global transcriptional regulatory programs of normal and tumor colon cells.

Cordero D, Solé X, Crous-Bou M, Sanz-Pamplona R, Paré-Brunet L, Guinó E, Olivares D, Berenguer A, Santos C, Salazar R, Biondo S, Moreno V.

BMC Cancer. 2014 Sep 24;14:708. doi: 10.1186/1471-2407-14-708.


Discovery and validation of new potential biomarkers for early detection of colon cancer.

Solé X, Crous-Bou M, Cordero D, Olivares D, Guinó E, Sanz-Pamplona R, Rodriguez-Moranta F, Sanjuan X, de Oca J, Salazar R, Moreno V.

PLoS One. 2014 Sep 12;9(9):e106748. doi: 10.1371/journal.pone.0106748. eCollection 2014.


Identification of candidate susceptibility genes for colorectal cancer through eQTL analysis.

Closa A, Cordero D, Sanz-Pamplona R, Solé X, Crous-Bou M, Paré-Brunet L, Berenguer A, Guino E, Lopez-Doriga A, Guardiola J, Biondo S, Salazar R, Moreno V.

Carcinogenesis. 2014 Sep;35(9):2039-46. doi: 10.1093/carcin/bgu092. Epub 2014 Apr 23.


Aberrant gene expression in mucosa adjacent to tumor reveals a molecular crosstalk in colon cancer.

Sanz-Pamplona R, Berenguer A, Cordero D, Molleví DG, Crous-Bou M, Sole X, Paré-Brunet L, Guino E, Salazar R, Santos C, de Oca J, Sanjuan X, Rodriguez-Moranta F, Moreno V.

Mol Cancer. 2014 Mar 5;13:46. doi: 10.1186/1476-4598-13-46.


Clinical value of prognosis gene expression signatures in colorectal cancer: a systematic review.

Sanz-Pamplona R, Berenguer A, Cordero D, Riccadonna S, Solé X, Crous-Bou M, Guinó E, Sanjuan X, Biondo S, Soriano A, Jurman G, Capella G, Furlanello C, Moreno V.

PLoS One. 2012;7(11):e48877. doi: 10.1371/journal.pone.0048877. Epub 2012 Nov 7. Review.


Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL.

Della Gatta G, Palomero T, Perez-Garcia A, Ambesi-Impiombato A, Bansal M, Carpenter ZW, De Keersmaecker K, Sole X, Xu L, Paietta E, Racevskis J, Wiernik PH, Rowe JM, Meijerink JP, Califano A, Ferrando AA.

Nat Med. 2012 Feb 26;18(3):436-40. doi: 10.1038/nm.2610.


Tools for protein-protein interaction network analysis in cancer research.

Sanz-Pamplona R, Berenguer A, Sole X, Cordero D, Crous-Bou M, Serra-Musach J, Guinó E, Pujana MÁ, Moreno V.

Clin Transl Oncol. 2012 Jan;14(1):3-14. Review.


The use of caspase inhibitors in pulsed-field gel electrophoresis may improve the estimation of radiation-induced DNA repair and apoptosis.

Balart J, Pueyo G, de Llobet LI, Baro M, Sole X, Marin S, Casanovas O, Mesia R, Capella G.

Radiat Oncol. 2011 Jan 15;6:6. doi: 10.1186/1748-717X-6-6.


The TLX1 oncogene drives aneuploidy in T cell transformation.

De Keersmaecker K, Real PJ, Gatta GD, Palomero T, Sulis ML, Tosello V, Van Vlierberghe P, Barnes K, Castillo M, Sole X, Hadler M, Lenz J, Aplan PD, Kelliher M, Kee BL, Pandolfi PP, Kappes D, Gounari F, Petrie H, Van der Meulen J, Speleman F, Paietta E, Racevskis J, Wiernik PH, Rowe JM, Soulier J, Avran D, Cavé H, Dastugue N, Raimondi S, Meijerink JP, Cordon-Cardo C, Califano A, Ferrando AA.

Nat Med. 2010 Nov;16(11):1321-7. doi: 10.1038/nm.2246. Epub 2010 Oct 24.


Biological reprogramming in acquired resistance to endocrine therapy of breast cancer.

Aguilar H, Solé X, Bonifaci N, Serra-Musach J, Islam A, López-Bigas N, Méndez-Pertuz M, Beijersbergen RL, Lázaro C, Urruticoechea A, Pujana MA.

Oncogene. 2010 Nov 11;29(45):6071-83. doi: 10.1038/onc.2010.333. Epub 2010 Aug 16.


Gene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis.

Fernández-Ramires R, Solé X, De Cecco L, Llort G, Cazorla A, Bonifaci N, Garcia MJ, Caldés T, Blanco I, Gariboldi M, Pierotti MA, Pujana MA, Benítez J, Osorio A.

Br J Cancer. 2009 Oct 20;101(8):1469-80. doi: 10.1038/sj.bjc.6605275.


Biological convergence of cancer signatures.

Solé X, Bonifaci N, López-Bigas N, Berenguer A, Hernández P, Reina O, Maxwell CA, Aguilar H, Urruticoechea A, de Sanjosé S, Comellas F, Capellá G, Moreno V, Pujana MA.

PLoS One. 2009;4(2):e4544. doi: 10.1371/journal.pone.0004544. Epub 2009 Feb 20.


Genetic and genomic analysis modeling of germline c-MYC overexpression and cancer susceptibility.

Solé X, Hernández P, de Heredia ML, Armengol L, Rodríguez-Santiago B, Gómez L, Maxwell CA, Aguiló F, Condom E, Abril J, Pérez-Jurado L, Estivill X, Nunes V, Capellá G, Gruber SB, Moreno V, Pujana MA.

BMC Genomics. 2008 Jan 11;9:12. doi: 10.1186/1471-2164-9-12.


Genetic interactions: the missing links for a better understanding of cancer susceptibility, progression and treatment.

Maxwell CA, Moreno V, Solé X, Gómez L, Hernández P, Urruticoechea A, Pujana MA.

Mol Cancer. 2008 Jan 10;7:4. doi: 10.1186/1476-4598-7-4.


Network modeling links breast cancer susceptibility and centrosome dysfunction.

Pujana MA, Han JD, Starita LM, Stevens KN, Tewari M, Ahn JS, Rennert G, Moreno V, Kirchhoff T, Gold B, Assmann V, Elshamy WM, Rual JF, Levine D, Rozek LS, Gelman RS, Gunsalus KC, Greenberg RA, Sobhian B, Bertin N, Venkatesan K, Ayivi-Guedehoussou N, Solé X, Hernández P, Lázaro C, Nathanson KL, Weber BL, Cusick ME, Hill DE, Offit K, Livingston DM, Gruber SB, Parvin JD, Vidal M.

Nat Genet. 2007 Nov;39(11):1338-49. Epub 2007 Oct 7.


Pre-clinical validation of early molecular markers of sensitivity to aromatase inhibitors in a mouse model of post-menopausal hormone-sensitive breast cancer.

Urruticoechea A, Aguilar H, Solé X, Capellà G, Martin LA, Dowsett M, Germà-Lluch JR.

Breast Cancer Res Treat. 2008 Jun;109(3):463-70. Epub 2007 Jul 19.


CLEAR-test: combining inference for differential expression and variability in microarray data analysis.

Valls J, Grau M, Solé X, Hernández P, Montaner D, Dopazo J, Peinado MA, Capellá G, Moreno V, Pujana MA.

J Biomed Inform. 2008 Feb;41(1):33-45. Epub 2007 May 17.


Genomic and transcriptomic prognostic factors in R0 Dukes B and C colorectal cancer patients.

Vendrell E, Ribas M, Valls J, Solé X, Grau M, Moreno V, Capellà G, Peinado MA.

Int J Oncol. 2007 May;30(5):1099-107.


Integrative analysis of a cancer somatic mutome.

Hernández P, Solé X, Valls J, Moreno V, Capellá G, Urruticoechea A, Pujana MA.

Mol Cancer. 2007 Feb 5;6:13.


SNPassoc: an R package to perform whole genome association studies.

González JR, Armengol L, Solé X, Guinó E, Mercader JM, Estivill X, Moreno V.

Bioinformatics. 2007 Mar 1;23(5):644-5. Epub 2007 Jan 31.


Molecular characterization of a t(9;12)(p21;q13) balanced chromosome translocation in combination with integrative genomics analysis identifies C9orf14 as a candidate tumor-suppressor.

Pujana MA, Ruiz A, Badenas C, Puig-Butille JA, Nadal M, Stark M, Gómez L, Valls J, Solé X, Hernández P, Cerrato C, Madrigal I, de Cid R, Aguilar H, Capellá G, Cal S, James MR, Walker GJ, Malvehy J, Milà M, Hayward NK, Estivill X, Puig S.

Genes Chromosomes Cancer. 2007 Feb;46(2):155-62.


SNPStats: a web tool for the analysis of association studies.

Solé X, Guinó E, Valls J, Iniesta R, Moreno V.

Bioinformatics. 2006 Aug 1;22(15):1928-9. Epub 2006 May 23.


Validation of RNA arbitrarily primed PCR probes hybridized to glass cDNA microarrays: application to the analysis of limited samples.

Grau M, Solé X, Obrador A, Tarafa G, Vendrell E, Valls J, Moreno V, Peinado MA, Capellá G.

Clin Chem. 2005 Jan;51(1):93-101.


Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer.

Frigola J, Solé X, Paz MF, Moreno V, Esteller M, Capellà G, Peinado MA.

Hum Mol Genet. 2005 Jan 15;14(2):319-26. Epub 2004 Dec 1.


[Sialography and sialotomography].

Grimalt AM, Sole XJ.

J Radiol Electrol Med Nucl. 1975;56 suppl 2:458-9. French. No abstract available.


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