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Items: 46


Targeting nuclear β-catenin as therapy for post-myeloproliferative neoplasm secondary AML.

Saenz DT, Fiskus W, Manshouri T, Mill CP, Qian Y, Raina K, Rajapakshe K, Coarfa C, Soldi R, Bose P, Borthakur G, Kadia TM, Khoury JD, Masarova L, Nowak AJ, Sun B, Saenz DN, Kornblau SM, Horrigan S, Sharma S, Qiu P, Crews CM, Verstovsek S, Bhalla KN.

Leukemia. 2019 Jun;33(6):1373-1386. doi: 10.1038/s41375-018-0334-3. Epub 2018 Dec 21.


Cleavage of Peptides from Amphibian Skin Revealed by Combining Analysis of Gland Secretion and in Situ MALDI Imaging Mass Spectrometry.

Brunetti AE, Marani MM, Soldi RA, Mendonça JN, Faivovich J, Cabrera GM, Lopes NP.

ACS Omega. 2018 May 31;3(5):5426-5434. doi: 10.1021/acsomega.7b02029. Epub 2018 May 21.


Reversible lysine-specific demethylase 1 antagonist HCI-2509 inhibits growth and decreases c-MYC in castration- and docetaxel-resistant prostate cancer cells.

Gupta S, Weston A, Bearrs J, Thode T, Neiss A, Soldi R, Sharma S.

Prostate Cancer Prostatic Dis. 2016 Dec;19(4):349-357. doi: 10.1038/pcan.2016.21. Epub 2016 Jun 28.


Folding of Fibroblast Growth Factor 1 Is Critical for Its Nonclassical Release.

Prudovsky I, Kacer D, Davis J, Shah V, Jayanthi S, Huber I, Dakshinamurthy R, Ganter O, Soldi R, Neivandt D, Guvench O, Suresh Kumar TK.

Biochemistry. 2016 Feb 23;55(7):1159-67. doi: 10.1021/acs.biochem.5b01341. Epub 2016 Feb 11.


Design, Synthesis, and Biological Evaluation of a Series of Anthracene-9,10-dione Dioxime β-Catenin Pathway Inhibitors.

Soldi R, Horrigan SK, Cholody MW, Padia J, Sorna V, Bearss J, Gilcrease G, Bhalla K, Verma A, Vankayalapati H, Sharma S.

J Med Chem. 2015 Aug 13;58(15):5854-62. doi: 10.1021/acs.jmedchem.5b00460. Epub 2015 Jul 31.


Genomic pathway analysis reveals that EZH2 and HDAC4 represent mutually exclusive epigenetic pathways across human cancers.

Cohen AL, Piccolo SR, Cheng L, Soldi R, Han B, Johnson WE, Bild AH.

BMC Med Genomics. 2013 Sep 30;6:35. doi: 10.1186/1755-8794-6-35.


(6R,10S)-Pallantione: the first ketone identified as sex pheromone in stink bugs.

Fávaro CF, Soldi RA, Ando T, Aldrich JR, Zarbin PH.

Org Lett. 2013 Apr 19;15(8):1822-5. doi: 10.1021/ol400413w. Epub 2013 Apr 1.


A phase I/II study of decitabine in combination with panitumumab in patients with wild-type (wt) KRAS metastatic colorectal cancer.

Garrido-Laguna I, McGregor KA, Wade M, Weis J, Gilcrease W, Burr L, Soldi R, Jakubowski L, Davidson C, Morrell G, Olpin JD, Boucher K, Jones D, Sharma S.

Invest New Drugs. 2013 Oct;31(5):1257-64. doi: 10.1007/s10637-013-9947-6. Epub 2013 Mar 17.


SIRT1 pathway dysregulation in the smoke-exposed airway epithelium and lung tumor tissue.

Beane J, Cheng L, Soldi R, Zhang X, Liu G, Anderlind C, Lenburg ME, Spira A, Bild AH.

Cancer Res. 2012 Nov 15;72(22):5702-11. doi: 10.1158/0008-5472.CAN-12-1043. Epub 2012 Sep 17.


The male-produced sex pheromone of the true bug, Phthia picta, is an unusual hydrocarbon.

Soldi RA, Rodrigues MA, Aldrich JR, Zarbin PH.

J Chem Ecol. 2012 Jul;38(7):814-24. doi: 10.1007/s10886-012-0147-1. Epub 2012 Jun 7.


A genomic approach to predict synergistic combinations for breast cancer treatment.

Soldi R, Cohen AL, Cheng L, Sun Y, Moos PJ, Bild AH.

Pharmacogenomics J. 2013 Feb;13(1):94-104. doi: 10.1038/tpj.2011.48. Epub 2011 Nov 15.


A pharmacogenomic method for individualized prediction of drug sensitivity.

Cohen AL, Soldi R, Zhang H, Gustafson AM, Wilcox R, Welm BE, Chang JT, Johnson E, Spira A, Jeffrey SS, Bild AH.

Mol Syst Biol. 2011 Jul 19;7:513. doi: 10.1038/msb.2011.47.


Airway PI3K pathway activation is an early and reversible event in lung cancer development.

Gustafson AM, Soldi R, Anderlind C, Scholand MB, Qian J, Zhang X, Cooper K, Walker D, McWilliams A, Liu G, Szabo E, Brody J, Massion PP, Lenburg ME, Lam S, Bild AH, Spira A.

Sci Transl Med. 2010 Apr 7;2(26):26ra25. doi: 10.1126/scitranslmed.3000251.


Novel cross-talk between three cardiovascular regulators: thrombin cleavage fragment of Jagged1 induces fibroblast growth factor 1 expression and release.

Duarte M, Kolev V, Kacer D, Mouta-Bellum C, Soldi R, Graziani I, Kirov A, Friesel R, Liaw L, Small D, Verdi J, Maciag T, Prudovsky I.

Mol Biol Cell. 2008 Nov;19(11):4863-74. doi: 10.1091/mbc.E07-12-1237. Epub 2008 Sep 10.


Secretion without Golgi.

Prudovsky I, Tarantini F, Landriscina M, Neivandt D, Soldi R, Kirov A, Small D, Kathir KM, Rajalingam D, Kumar TK.

J Cell Biochem. 2008 Apr 1;103(5):1327-43. Review.


Sphingosine kinase 1 is a critical component of the copper-dependent FGF1 export pathway.

Soldi R, Mandinova A, Venkataraman K, Hla T, Vadas M, Pitson S, Duarte M, Graziani I, Kolev V, Kacer D, Kirov A, Maciag T, Prudovsky I.

Exp Cell Res. 2007 Sep 10;313(15):3308-18. Epub 2007 Jul 6.


Thrombin induces rapid PAR1-mediated non-classical FGF1 release.

Duarte M, Kolev V, Soldi R, Kirov A, Graziani I, Oliveira SM, Kacer D, Friesel R, Maciag T, Prudovsky I.

Biochem Biophys Res Commun. 2006 Nov 24;350(3):604-9. Epub 2006 Sep 28.


Release of FGF1 and p40 synaptotagmin 1 correlates with their membrane destabilizing ability.

Graziani I, Bagalá C, Duarte M, Soldi R, Kolev V, Tarantini F, Kumar TK, Doyle A, Neivandt D, Yu C, Maciag T, Prudovsky I.

Biochem Biophys Res Commun. 2006 Oct 13;349(1):192-9. Epub 2006 Aug 14.


Molecular mechanism of inhibition of nonclassical FGF-1 export.

Rajalingam D, Kumar TK, Soldi R, Graziani I, Prudovsky I, Yu C.

Biochemistry. 2005 Nov 29;44(47):15472-9.


The intracellular domain of Notch ligand Delta1 induces cell growth arrest.

Kolev V, Kacer D, Trifonova R, Small D, Duarte M, Soldi R, Graziani I, Sideleva O, Larman B, Maciag T, Prudovsky I.

FEBS Lett. 2005 Oct 24;579(25):5798-5802.


The non-transmembrane form of Delta1, but not of Jagged1, induces normal migratory behavior accompanied by fibroblast growth factor receptor 1-dependent transformation.

Trifonova R, Small D, Kacer D, Kovalenko D, Kolev V, Mandinova A, Soldi R, Liaw L, Prudovsky I, Maciag T.

J Biol Chem. 2004 Apr 2;279(14):13285-8. Epub 2004 Feb 9.


The non-classical export routes: FGF1 and IL-1alpha point the way.

Prudovsky I, Mandinova A, Soldi R, Bagala C, Graziani I, Landriscina M, Tarantini F, Duarte M, Bellum S, Doherty H, Maciag T.

J Cell Sci. 2003 Dec 15;116(Pt 24):4871-81. Review.


The alternative translation of synaptotagmin 1 mediates the non-classical release of FGF1.

Bagalá C, Kolev V, Mandinova A, Soldi R, Mouta C, Graziani I, Prudovsky I, Maciag T.

Biochem Biophys Res Commun. 2003 Oct 31;310(4):1041-7.


Interleukin 1: the choreographer for the restenotic ballet.

Mandinov L, Mandinova A, Soldi R, Graziani I, Bagala C, Prudovsky I, Maciag T.

Thromb Haemost. 2003 Sep;90(3):369-71. No abstract available.


Copper chelation represses the vascular response to injury.

Mandinov L, Mandinova A, Kyurkchiev S, Kyurkchiev D, Kehayov I, Kolev V, Soldi R, Bagala C, de Muinck ED, Lindner V, Post MJ, Simons M, Bellum S, Prudovsky I, Maciag T.

Proc Natl Acad Sci U S A. 2003 May 27;100(11):6700-5. Epub 2003 May 16.


S100A13 mediates the copper-dependent stress-induced release of IL-1alpha from both human U937 and murine NIH 3T3 cells.

Mandinova A, Soldi R, Graziani I, Bagala C, Bellum S, Landriscina M, Tarantini F, Prudovsky I, Maciag T.

J Cell Sci. 2003 Jul 1;116(Pt 13):2687-96. Epub 2003 May 13.


Notch activation suppresses fibroblast growth factor-dependent cellular transformation.

Small D, Kovalenko D, Soldi R, Mandinova A, Kolev V, Trifonova R, Bagala C, Kacer D, Battelli C, Liaw L, Prudovsky I, Maciag T.

J Biol Chem. 2003 May 2;278(18):16405-13. Epub 2003 Feb 21.


The intracellular translocation of the components of the fibroblast growth factor 1 release complex precedes their assembly prior to export.

Prudovsky I, Bagala C, Tarantini F, Mandinova A, Soldi R, Bellum S, Maciag T.

J Cell Biol. 2002 Jul 22;158(2):201-8. Epub 2002 Jul 22.


Copper induces the assembly of a multiprotein aggregate implicated in the release of fibroblast growth factor 1 in response to stress.

Landriscina M, Bagalá C, Mandinova A, Soldi R, Micucci I, Bellum S, Prudovsky I, Maciag T.

J Biol Chem. 2001 Jul 6;276(27):25549-57. Epub 2001 May 10.


S100A13 participates in the release of fibroblast growth factor 1 in response to heat shock in vitro.

Landriscina M, Soldi R, Bagalá C, Micucci I, Bellum S, Tarantini F, Prudovsky I, Maciag T.

J Biol Chem. 2001 Jun 22;276(25):22544-52. Epub 2001 Apr 16. Erratum in: J Biol Chem 2001 Aug 10;276(32):30571.


Fusions to members of fibroblast growth factor gene family to study nuclear translocation and nonclassic exocytosis.

Prudovsky I, Landriscina M, Soldi R, Bellum S, Small D, Andreeva V, Maciag T.

Methods Enzymol. 2000;327:369-82. No abstract available.


Amlexanox reversibly inhibits cell migration and proliferation and induces the Src-dependent disassembly of actin stress fibers in vitro.

Landriscina M, Prudovsky I, Mouta Carreira C, Soldi R, Tarantini F, Maciag T.

J Biol Chem. 2000 Oct 20;275(42):32753-62.


Identification of specific molecular structures of human immunodeficiency virus type 1 Tat relevant for its biological effects on vascular endothelial cells.

Mitola S, Soldi R, Zanon I, Barra L, Gutierrez MI, Berkhout B, Giacca M, Bussolino F.

J Virol. 2000 Jan;74(1):344-53.


Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.

Soldi R, Mitola S, Strasly M, Defilippi P, Tarone G, Bussolino F.

EMBO J. 1999 Feb 15;18(4):882-92.


Activation of JAK2 in human vascular endothelial cells by granulocyte-macrophage colony-stimulating factor.

Soldi R, Primo L, Brizzi MF, Sanavio F, Aglietta M, Polentarutti N, Pegoraro L, Mantovani A, Bussolino F.

Blood. 1997 Feb 1;89(3):863-72.


Angiogenesis induced in vivo by hepatocyte growth factor is mediated by platelet-activating factor synthesis from macrophages.

Camussi G, Montrucchio G, Lupia E, Soldi R, Comoglio PM, Bussolino F.

J Immunol. 1997 Feb 1;158(3):1302-9.


The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells.

Albini A, Soldi R, Giunciuglio D, Giraudo E, Benelli R, Primo L, Noonan D, Salio M, Camussi G, Rockl W, Bussolino F.

Nat Med. 1996 Dec;2(12):1371-5.


Platelet-activating factor (PAF) induces the early tyrosine phosphorylation of focal adhesion kinase (p125FAK) in human endothelial cells.

Soldi R, Sanavio F, Aglietta M, Primo L, Defilippi P, Marchisio PC, Bussolino F.

Oncogene. 1996 Aug 1;13(3):515-25.


Anti-tumor activity of cytokines against opportunistic vascular tumors in mice.

Dong QG, Graziani A, Garlanda C, De Calmanovici RW, Arese M, Soldi R, Vecchi A, Mantovani A, Bussolino F.

Int J Cancer. 1996 Mar 1;65(5):700-8.


Multiple roles of platelet-activating factor in the nervous system.

Bussolino F, Soldi R, Arese M, Jaranowska A, Sogos V, Gremo F.

Neurochem Int. 1995 May;26(5):425-33. Review. No abstract available.


Middle T antigen-transformed endothelial cells exhibit an increased activity of nitric oxide synthase.

Ghigo D, Arese M, Todde R, Vecchi A, Silvagno F, Costamagna C, Dong QG, Alessio M, Heller R, Soldi R, Trucco F, Garbarino G, Pescarmona G, Mantovani A, Bussolino F, Bosia A.

J Exp Med. 1995 Jan 1;181(1):9-19.


Involvement of a serine protease in the synthesis of platelet-activating factor by endothelial cells stimulated by tumor necrosis factor-alpha or interleukin-1 alpha.

Bussolino F, Arese M, Silvestro L, Soldi R, Benfenati E, Sanavio F, Aglietta M, Bosia A, Camussi G.

Eur J Immunol. 1994 Dec;24(12):3131-9.


Actions of molecules which regulate hemopoiesis on endothelial cells: memoirs of common ancestors?

Bussolino F, Bocchietto E, Silvagno F, Soldi R, Arese M, Mantovani A.

Pathol Res Pract. 1994 Oct;190(9-10):834-9. Review.


Oncostatin M activates phosphatidylinositol-3-kinase in Kaposi's sarcoma cells.

Soldi R, Graziani A, Benelli R, Ghigo D, Bosia A, Albini A, Bussolino F.

Oncogene. 1994 Aug;9(8):2253-60.


Human endothelial cells are targets for platelet-activating factor (PAF). Activation of alpha and beta protein kinase C isozymes in endothelial cells stimulated by PAF.

Bussolino F, Silvagno F, Garbarino G, Costamagna C, Sanavio F, Arese M, Soldi R, Aglietta M, Pescarmona G, Camussi G, et al.

J Biol Chem. 1994 Jan 28;269(4):2877-86.


Genome size and karyotype length in some interstitial polychaete species of the genus Ophryotrocha (Dorvilleidae).

Sella G, Redi CA, Ramella L, Soldi R, Premoli MC.

Genome. 1993 Aug;36(4):652-7.


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