Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 339

1.

Coronary arterial vasculature in the pathophysiology of hypertrophic cardiomyopathy.

Marszalek RJ, Solaro RJ, Wolska BM.

Pflugers Arch. 2018 Oct 29. doi: 10.1007/s00424-018-2224-y. [Epub ahead of print] Review.

PMID:
30370501
2.

Role of the C-terminus mobile domain of cardiac troponin I in the regulation of thin filament activation in skinned papillary muscle strips.

Bohlooli Ghashghaee N, Li KL, Solaro RJ, Dong WJ.

Arch Biochem Biophys. 2018 Jun 15;648:27-35. doi: 10.1016/j.abb.2018.04.014. Epub 2018 Apr 25.

PMID:
29704484
3.

Loss of p21-activated kinase 1 (Pak1) promotes atrial arrhythmic activity.

DeSantiago J, Bare DJ, Varma D, Solaro RJ, Arora R, Banach K.

Heart Rhythm. 2018 Aug;15(8):1233-1241. doi: 10.1016/j.hrthm.2018.03.041. Epub 2018 Apr 3.

PMID:
29625277
4.

Analysis of the editorial review process of the Journal of Molecular and Cellular Cardiology.

Danziger RS, Nordgren RK, Singh M, Solaro RJ, Berbaum ML.

J Mol Cell Cardiol. 2018 Jan;114:124-128. doi: 10.1016/j.yjmcc.2017.11.002. Epub 2017 Nov 7. No abstract available.

PMID:
29122579
5.

Early sensitization of myofilaments to Ca2+ prevents genetically linked dilated cardiomyopathy in mice.

Alves ML, Warren CM, Simon JN, Gaffin RD, Montminy EM, Wieczorek DF, Solaro RJ, Wolska BM.

Cardiovasc Res. 2017 Jul 1;113(8):915-925. doi: 10.1093/cvr/cvx068.

6.

Deficiency of cardiomyocyte-specific microRNA-378 contributes to the development of cardiac fibrosis involving a transforming growth factor β (TGFβ1)-dependent paracrine mechanism.

Nagalingam RS, Sundaresan NR, Noor M, Gupta MP, Solaro RJ, Gupta M.

J Biol Chem. 2017 Mar 24;292(12):5124. doi: 10.1074/jbc.A114.580977. No abstract available.

7.

A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling.

Nagalingam RS, Sundaresan NR, Gupta MP, Geenen DL, Solaro RJ, Gupta M.

J Biol Chem. 2017 Mar 24;292(12):5123. doi: 10.1074/jbc.A112.442384. No abstract available.

8.

Peroxisome proliferator-activated receptor-α expression induces alterations in cardiac myofilaments in a pressure-overload model of hypertrophy.

Karam CN, Warren CM, Henze M, Banke NH, Lewandowski ED, Solaro RJ.

Am J Physiol Heart Circ Physiol. 2017 Apr 1;312(4):H681-H690. doi: 10.1152/ajpheart.00469.2016. Epub 2017 Jan 27.

9.

Long-Term Biased β-Arrestin Signaling Improves Cardiac Structure and Function in Dilated Cardiomyopathy.

Ryba DM, Li J, Cowan CL, Russell B, Wolska BM, Solaro RJ.

Circulation. 2017 Mar 14;135(11):1056-1070. doi: 10.1161/CIRCULATIONAHA.116.024482. Epub 2017 Jan 19.

10.

Into the golden anniversary of the yellow journal.

Solaro RJ.

J Mol Cell Cardiol. 2017 Jan;102:117-118. doi: 10.1016/j.yjmcc.2017.01.003. Epub 2017 Jan 8. No abstract available.

PMID:
28077294
11.

β-Arrestin mediates the Frank-Starling mechanism of cardiac contractility.

Abraham DM, Davis RT 3rd, Warren CM, Mao L, Wolska BM, Solaro RJ, Rockman HA.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14426-14431. Epub 2016 Nov 28.

12.

A myosin activator improves actin assembly and sarcomere function of human-induced pluripotent stem cell-derived cardiomyocytes with a troponin T point mutation.

Broughton KM, Li J, Sarmah E, Warren CM, Lin YH, Henze MP, Sanchez-Freire V, Solaro RJ, Russell B.

Am J Physiol Heart Circ Physiol. 2016 Jul 1;311(1):H107-17. doi: 10.1152/ajpheart.00162.2016. Epub 2016 May 6.

13.

Sarcomere length dependent effects on the interaction between cTnC and cTnI in skinned papillary muscle strips.

Li KL, Ghashghaee NB, Solaro RJ, Dong W.

Arch Biochem Biophys. 2016 Jul 1;601:69-79. doi: 10.1016/j.abb.2016.02.030. Epub 2016 Mar 2.

14.

Editorial: Ca(2+) Signaling and Heart Rhythm.

Huang CL, Solaro RJ, Ke Y, Lei M.

Front Physiol. 2016 Jan 11;6:423. doi: 10.3389/fphys.2015.00423. eCollection 2015. No abstract available.

15.

Why we need to understand the mechanics of developing cardiac sarcomeres in humans.

Solaro RJ.

J Physiol. 2016 Jan 15;594(2):255. doi: 10.1113/JP271706. No abstract available.

16.

Green Tea Catechin Normalizes the Enhanced Ca2+ Sensitivity of Myofilaments Regulated by a Hypertrophic Cardiomyopathy-Associated Mutation in Human Cardiac Troponin I (K206I).

Warren CM, Karam CN, Wolska BM, Kobayashi T, de Tombe PP, Arteaga GM, Bos JM, Ackerman MJ, Solaro RJ.

Circ Cardiovasc Genet. 2015 Dec;8(6):765-73. doi: 10.1161/CIRCGENETICS.115.001234. Epub 2015 Nov 9.

17.

Knockout of p21-activated kinase-1 attenuates exercise-induced cardiac remodelling through altered calcineurin signalling.

Davis RT 3rd, Simon JN, Utter M, Mungai P, Alvarez MG, Chowdhury SA, Heydemann A, Ke Y, Wolska BM, Solaro RJ.

Cardiovasc Res. 2015 Dec 1;108(3):335-47. doi: 10.1093/cvr/cvv234. Epub 2015 Oct 12.

18.

N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy.

Wilder T, Ryba DM, Wieczorek DF, Wolska BM, Solaro RJ.

Am J Physiol Heart Circ Physiol. 2015 Nov 15;309(10):H1720-30. doi: 10.1152/ajpheart.00339.2015. Epub 2015 Oct 2.

19.

A sarcomeric protein tongue-twister: post-translation, citrullination/deimination and elimination of arginine residues.

Solaro RJ.

Cardiovasc Res. 2015 Nov 1;108(2):212-4. doi: 10.1093/cvr/cvv220. Epub 2015 Sep 20. No abstract available.

PMID:
26392345
20.

Omecamtiv Mecarbil, a Cardiac Myosin Activator, Increases Ca2+ Sensitivity in Myofilaments With a Dilated Cardiomyopathy Mutant Tropomyosin E54K.

Utter MS, Ryba DM, Li BH, Wolska BM, Solaro RJ.

J Cardiovasc Pharmacol. 2015 Oct;66(4):347-53. doi: 10.1097/FJC.0000000000000286.

21.

Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model.

Tarigopula M, Davis RT 3rd, Mungai PT, Ryba DM, Wieczorek DF, Cowan CL, Violin JD, Wolska BM, Solaro RJ.

Cardiovasc Res. 2015 Jul 15;107(2):226-34. doi: 10.1093/cvr/cvv162. Epub 2015 Jun 4.

22.

Impact of anesthesia and storage on posttranslational modifications of cardiac myofilament proteins.

Utter MS, Warren CM, Solaro RJ.

Physiol Rep. 2015 May;3(5). pii: e12393. doi: 10.14814/phy2.12393.

23.

Novel insights into mechanisms for Pak1-mediated regulation of cardiac Ca(2+) homeostasis.

Wang Y, Tsui H, Bolton EL, Wang X, Huang CL, Solaro RJ, Ke Y, Lei M.

Front Physiol. 2015 Mar 17;6:76. doi: 10.3389/fphys.2015.00076. eCollection 2015. Review.

24.

Phosphorylation of cardiac Myosin-binding protein-C is a critical mediator of diastolic function.

Rosas PC, Liu Y, Abdalla MI, Thomas CM, Kidwell DT, Dusio GF, Mukhopadhyay D, Kumar R, Baker KM, Mitchell BM, Powers PA, Fitzsimons DP, Patel BG, Warren CM, Solaro RJ, Moss RL, Tong CW.

Circ Heart Fail. 2015 May;8(3):582-94. doi: 10.1161/CIRCHEARTFAILURE.114.001550. Epub 2015 Mar 4.

25.

Regulation of Ca(2+) transient by PP2A in normal and failing heart.

Lei M, Wang X, Ke Y, Solaro RJ.

Front Physiol. 2015 Jan 29;6:13. doi: 10.3389/fphys.2015.00013. eCollection 2015. Review.

26.

A novel and personalized rehabilitation program for obese kidney transplant recipients.

Tzvetanov I, West-Thielke P, D'Amico G, Johnsen M, Ladik A, Hachaj G, Grazman M, Heller RU, Fernhall B, Daviglus ML, Solaro RJ, Oberholzer J, Gallon L, Benedetti E.

Transplant Proc. 2014 Dec;46(10):3431-7. doi: 10.1016/j.transproceed.2014.05.085.

PMID:
25498067
27.

Metabolic efficiency promotes protection from pressure overload in hearts expressing slow skeletal troponin I.

Carley AN, Taglieri DM, Bi J, Solaro RJ, Lewandowski ED.

Circ Heart Fail. 2015 Jan;8(1):119-27. doi: 10.1161/CIRCHEARTFAILURE.114.001496. Epub 2014 Nov 25.

28.

PAK1 is a novel cardiac protective signaling molecule.

Ke Y, Wang X, Jin XY, Solaro RJ, Lei M.

Front Med. 2014 Dec;8(4):399-403. doi: 10.1007/s11684-014-0380-9. Epub 2014 Nov 22. Review.

PMID:
25416031
29.

Computational studies of the effect of the S23D/S24D troponin I mutation on cardiac troponin structural dynamics.

Cheng Y, Lindert S, Kekenes-Huskey P, Rao VS, Solaro RJ, Rosevear PR, Amaro R, McCulloch AD, McCammon JA, Regnier M.

Biophys J. 2014 Oct 7;107(7):1675-85. doi: 10.1016/j.bpj.2014.08.008.

30.

Ceramide-mediated depression in cardiomyocyte contractility through PKC activation and modulation of myofilament protein phosphorylation.

Simon JN, Chowdhury SA, Warren CM, Sadayappan S, Wieczorek DF, Solaro RJ, Wolska BM.

Basic Res Cardiol. 2014;109(6):445. doi: 10.1007/s00395-014-0445-6. Epub 2014 Oct 4.

31.

Pak1 is required to maintain ventricular Ca²⁺ homeostasis and electrophysiological stability through SERCA2a regulation in mice.

Wang Y, Tsui H, Ke Y, Shi Y, Li Y, Davies L, Cartwright EJ, Venetucci L, Zhang H, Terrar DA, Huang CL, Solaro RJ, Wang X, Lei M.

Circ Arrhythm Electrophysiol. 2014 Oct;7(5):938-48. doi: 10.1161/CIRCEP.113.001198. Epub 2014 Sep 12.

32.

Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes.

Briston SJ, Dibb KM, Solaro RJ, Eisner DA, Trafford AW.

Cardiovasc Res. 2014 Nov 1;104(2):347-54. doi: 10.1093/cvr/cvu201. Epub 2014 Sep 2.

33.

Deficiency of cardiomyocyte-specific microRNA-378 contributes to the development of cardiac fibrosis involving a transforming growth factor β (TGFβ1)-dependent paracrine mechanism.

Nagalingam RS, Sundaresan NR, Noor M, Gupta MP, Solaro RJ, Gupta M.

J Biol Chem. 2014 Sep 26;289(39):27199-214. doi: 10.1074/jbc.M114.580977. Epub 2014 Aug 7. Retraction in: J Biol Chem. 2017 Mar 24;292(12 ):5124.

34.

In situ time-resolved FRET reveals effects of sarcomere length on cardiac thin-filament activation.

Li KL, Rieck D, Solaro RJ, Dong W.

Biophys J. 2014 Aug 5;107(3):682-693. doi: 10.1016/j.bpj.2014.05.044.

35.

Cardiac proteomics.

Burniston JG, Gramolini AO, Solaro RJ.

Biomed Res Int. 2014;2014:903538. doi: 10.1155/2014/903538. Epub 2014 Jun 15. No abstract available.

36.

Inhibition of angiotensin II-induced cardiac hypertrophy and associated ventricular arrhythmias by a p21 activated kinase 1 bioactive peptide.

Wang R, Wang Y, Lin WK, Zhang Y, Liu W, Huang K, Terrar DA, Solaro RJ, Wang X, Ke Y, Lei M.

PLoS One. 2014 Jul 11;9(7):e101974. doi: 10.1371/journal.pone.0101974. eCollection 2014.

37.

Cardiomyocyte-specific expression of CRNK, the C-terminal domain of PYK2, maintains ventricular function and slows ventricular remodeling in a mouse model of dilated cardiomyopathy.

Koshman YE, Chu M, Kim T, Kalmanson O, Farjah M, Kumar M, Lewis W, Geenen DL, de Tombe P, Goldspink PH, Solaro RJ, Samarel AM.

J Mol Cell Cardiol. 2014 Jul;72:281-91. doi: 10.1016/j.yjmcc.2014.03.021. Epub 2014 Apr 5.

38.

S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding.

Alegre-Cebollada J, Kosuri P, Giganti D, Eckels E, Rivas-Pardo JA, Hamdani N, Warren CM, Solaro RJ, Linke WA, Fernández JM.

Cell. 2014 Mar 13;156(6):1235-1246. doi: 10.1016/j.cell.2014.01.056.

39.

Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins.

Alves ML, Dias FAL, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT Rd, Sakthivel S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM.

Circ Cardiovasc Genet. 2014 Apr;7(2):132-143. doi: 10.1161/CIRCGENETICS.113.000324. Epub 2014 Feb 28. Erratum in: Circ Cardiovasc Genet. 2014 Jun;7(3):397.

40.

Maladaptive modifications in myofilament proteins and triggers in the progression to heart failure and sudden death.

Yar S, Monasky MM, Solaro RJ.

Pflugers Arch. 2014 Jun;466(6):1189-97. doi: 10.1007/s00424-014-1457-7. Epub 2014 Feb 1. Review.

41.

Influence of a constitutive increase in myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and contraction of mouse heart ventricular myocytes.

Puglisi JL, Goldspink PH, Gomes AV, Utter MS, Bers DM, Solaro RJ.

Arch Biochem Biophys. 2014 Jun 15;552-553:50-9. doi: 10.1016/j.abb.2014.01.019. Epub 2014 Jan 27.

42.

PR65A phosphorylation regulates PP2A complex signaling.

Kotlo K, Xing Y, Lather S, Grillon JM, Johnson K, Skidgel RA, Solaro RJ, Danziger RS.

PLoS One. 2014 Jan 21;9(1):e85000. doi: 10.1371/journal.pone.0085000. eCollection 2014.

43.

p21-Activated kinase1 (Pak1) is a negative regulator of NADPH-oxidase 2 in ventricular myocytes.

DeSantiago J, Bare DJ, Xiao L, Ke Y, Solaro RJ, Banach K.

J Mol Cell Cardiol. 2014 Feb;67:77-85. doi: 10.1016/j.yjmcc.2013.12.017. Epub 2013 Dec 28.

44.

Novel control of cardiac myofilament response to calcium by S-glutathionylation at specific sites of myosin binding protein C.

Patel BG, Wilder T, Solaro RJ.

Front Physiol. 2013 Nov 20;4:336. doi: 10.3389/fphys.2013.00336. eCollection 2013.

45.

Unique catalytic activities and scaffolding of p21 activated kinase-1 in cardiovascular signaling.

Ke Y, Lei M, Wang X, Solaro RJ.

Front Pharmacol. 2013 Sep 27;4:116. doi: 10.3389/fphar.2013.00116. Review.

46.

Decreasing tropomyosin phosphorylation rescues tropomyosin-induced familial hypertrophic cardiomyopathy.

Schulz EM, Wilder T, Chowdhury SA, Sheikh HN, Wolska BM, Solaro RJ, Wieczorek DF.

J Biol Chem. 2013 Oct 4;288(40):28925-35. doi: 10.1074/jbc.M113.466466. Epub 2013 Aug 19.

47.

Structural basis for the in situ Ca(2+) sensitization of cardiac troponin C by positive feedback from force-generating myosin cross-bridges.

Rieck DC, Li KL, Ouyang Y, Solaro RJ, Dong WJ.

Arch Biochem Biophys. 2013 Sep 15;537(2):198-209. doi: 10.1016/j.abb.2013.07.013. Epub 2013 Jul 26.

48.

The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium.

Monasky MM, Taglieri DM, Henze M, Warren CM, Utter MS, Soergel DG, Violin JD, Solaro RJ.

Am J Physiol Heart Circ Physiol. 2013 Sep 15;305(6):H856-66. doi: 10.1152/ajpheart.00327.2013. Epub 2013 Jul 19.

49.

A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin.

Liu W, Zi M, Tsui H, Chowdhury SK, Zeef L, Meng QJ, Travis M, Prehar S, Berry A, Hanley NA, Neyses L, Xiao RP, Oceandy D, Ke Y, Solaro RJ, Cartwright EJ, Lei M, Wang X.

Circ Heart Fail. 2013 Jul;6(4):833-44. doi: 10.1161/CIRCHEARTFAILURE.112.000123. Epub 2013 Jun 10.

50.

Functional integrity of the T-tubular system in cardiomyocytes depends on p21-activated kinase 1.

DeSantiago J, Bare DJ, Ke Y, Sheehan KA, Solaro RJ, Banach K.

J Mol Cell Cardiol. 2013 Jul;60:121-8. doi: 10.1016/j.yjmcc.2013.04.014. Epub 2013 Apr 20.

Supplemental Content

Loading ...
Support Center