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Items: 20


Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations.

Pahuja KB, Nguyen TT, Jaiswal BS, Prabhash K, Thaker TM, Senger K, Chaudhuri S, Kljavin NM, Antony A, Phalke S, Kumar P, Mravic M, Stawiski EW, Vargas D, Durinck S, Gupta R, Khanna-Gupta A, Trabucco SE, Sokol ES, Hartmaier RJ, Singh A, Chougule A, Trivedi V, Dutt A, Patil V, Joshi A, Noronha V, Ziai J, Banavali SD, Ramprasad V, DeGrado WF, Bueno R, Jura N, Seshagiri S.

Cancer Cell. 2018 Nov 12;34(5):792-806.e5. doi: 10.1016/j.ccell.2018.09.010. Epub 2018 Oct 25.


Loss of function of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular breast cancer.

Sokol ES, Feng YX, Jin DX, Basudan A, Lee AV, Atkinson JM, Chen J, Stephens PJ, Frampton GM, Gupta PB, Ross JS, Chung JH, Oesterreich S, Ali SM, Hartmaier RJ.

Ann Oncol. 2019 Jan 1;30(1):115-123. doi: 10.1093/annonc/mdy497.


Frequent ESR1 and CDK Pathway Copy-Number Alterations in Metastatic Breast Cancer.

Basudan A, Priedigkeit N, Hartmaier RJ, Sokol ES, Bahreini A, Watters RJ, Boisen MM, Bhargava R, Weiss KR, Karsten MM, Denkert C, Blohmer JU, Leone JP, Hamilton RL, Brufsky AM, Elishaev E, Lucas PC, Lee AV, Oesterreich S.

Mol Cancer Res. 2019 Feb;17(2):457-468. doi: 10.1158/1541-7786.MCR-18-0946. Epub 2018 Oct 24.


Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers.

Pozdeyev N, Gay LM, Sokol ES, Hartmaier R, Deaver KE, Davis S, French JD, Borre PV, LaBarbera DV, Tan AC, Schweppe RE, Fishbein L, Ross JS, Haugen BR, Bowles DW.

Clin Cancer Res. 2018 Jul 1;24(13):3059-3068. doi: 10.1158/1078-0432.CCR-18-0373. Epub 2018 Apr 3.


BCL11B Drives Human Mammary Stem Cell Self-Renewal In Vitro by Inhibiting Basal Differentiation.

Miller DH, Jin DX, Sokol ES, Cabrera JR, Superville DA, Gorelov RA, Kuperwasser C, Gupta PB.

Stem Cell Reports. 2018 Mar 13;10(3):1131-1145. doi: 10.1016/j.stemcr.2018.01.036. Epub 2018 Mar 1.


Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1.

Feng YX, Jin DX, Sokol ES, Reinhardt F, Miller DH, Gupta PB.

Nat Commun. 2017 Oct 20;8(1):1079. doi: 10.1038/s41467-017-01052-y.


3D Primary Culture Model to Study Human Mammary Development.

Miller DH, Sokol ES, Gupta PB.

Methods Mol Biol. 2017;1612:139-147. doi: 10.1007/978-1-4939-7021-6_10.


SMARCE1 is required for the invasive progression of in situ cancers.

Sokol ES, Feng YX, Jin DX, Tizabi MD, Miller DH, Cohen MA, Sanduja S, Reinhardt F, Pandey J, Superville DA, Jaenisch R, Gupta PB.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4153-4158. doi: 10.1073/pnas.1703931114. Epub 2017 Apr 4.


Cancer cells exhibit clonal diversity in phenotypic plasticity.

Mathis RA, Sokol ES, Gupta PB.

Open Biol. 2017 Feb;7(2). pii: 160283. doi: 10.1098/rsob.160283.


AMPK promotes tolerance to Ras pathway inhibition by activating autophagy.

Sanduja S, Feng Y, Mathis RA, Sokol ES, Reinhardt F, Halaban R, Gupta PB.

Oncogene. 2016 Oct 6;35(40):5295-5303. doi: 10.1038/onc.2016.70. Epub 2016 Apr 4.


Growth of human breast tissues from patient cells in 3D hydrogel scaffolds.

Sokol ES, Miller DH, Breggia A, Spencer KC, Arendt LM, Gupta PB.

Breast Cancer Res. 2016 Mar 1;18(1):19. doi: 10.1186/s13058-016-0677-5.


Perturbation-expression analysis identifies RUNX1 as a regulator of human mammary stem cell differentiation.

Sokol ES, Sanduja S, Jin DX, Miller DH, Mathis RA, Gupta PB.

PLoS Comput Biol. 2015 Apr 20;11(4):e1004161. doi: 10.1371/journal.pcbi.1004161. eCollection 2015 Apr.


Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state.

Katz Y, Li F, Lambert NJ, Sokol ES, Tam WL, Cheng AW, Airoldi EM, Lengner CJ, Gupta PB, Yu Z, Jaenisch R, Burge CB.

Elife. 2014 Nov 7;3:e03915. doi: 10.7554/eLife.03915.


De-differentiation confers multidrug resistance via noncanonical PERK-Nrf2 signaling.

Del Vecchio CA, Feng Y, Sokol ES, Tillman EJ, Sanduja S, Reinhardt F, Gupta PB.

PLoS Biol. 2014 Sep 9;12(9):e1001945. doi: 10.1371/journal.pbio.1001945. eCollection 2014 Sep.


Epithelial-to-mesenchymal transition activates PERK-eIF2╬▒ and sensitizes cells to endoplasmic reticulum stress.

Feng YX, Sokol ES, Del Vecchio CA, Sanduja S, Claessen JH, Proia TA, Jin DX, Reinhardt F, Ploegh HL, Wang Q, Gupta PB.

Cancer Discov. 2014 Jun;4(6):702-15. doi: 10.1158/2159-8290.CD-13-0945. Epub 2014 Apr 4.


The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition.

Feng YX, Sokol ES, Gupta PB.

Mol Cell Oncol. 2014 Oct 29;1(2):e961822. doi: 10.4161/23723548.2014.961822. eCollection 2014 Apr-Jun.


GDP-mannose-4,6-dehydratase is a cytosolic partner of tankyrase 1 that inhibits its poly(ADP-ribose) polymerase activity.

Bisht KK, Dudognon C, Chang WG, Sokol ES, Ramirez A, Smith S.

Mol Cell Biol. 2012 Aug;32(15):3044-53. doi: 10.1128/MCB.00258-12. Epub 2012 May 29.


Transcriptional repression by the proximal exonic region at the human TERT gene.

Wong TC, Sokol ES, Schep AN, Punjiya M, Tran DA, Allan D, Drewell RA.

Gene. 2011 Oct 15;486(1-2):65-73. doi: 10.1016/j.gene.2011.07.016. Epub 2011 Jul 20.


Promoting responsiveness between mothers with depressive symptoms and their infants.

Horowitz JA, Bell M, Trybulski J, Munro BH, Moser D, Hartz SA, McCordic L, Sokol ES.

J Nurs Scholarsh. 2001;33(4):323-9.


Role of mammography with palpable breast lesions.

Sokol ES, Walker B, Terz JJ, Lawrence W Jr.

Surgery. 1970 May;67(5):748-53. No abstract available.


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