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The Scottish Intercollegiate Guidelines Network (SIGN) 157: Guidelines on Risk Reduction and Management of Delirium.

Soiza RL, Myint PK.

Medicina (Kaunas). 2019 Aug 15;55(8). pii: E491. doi: 10.3390/medicina55080491.


Variability in the clinical management of iron deficiency anaemia in older adults: results from a survey of UK specialists in the care of older people.

Donaldson AIC, Soiza RL, Hands KJ, Witham MD, Myint PK.

Ther Adv Drug Saf. 2019 Jun 13;10:2042098619854870. doi: 10.1177/2042098619854870. eCollection 2019.


Effect of Vitamin K2 on Postural Sway in Older People Who Fall: A Randomized Controlled Trial.

Witham MD, Price RJG, Band MM, Hannah MS, Fulton RL, Clarke CL, Donnan PT, McNamee P, Cvoro V, Soiza RL.

J Am Geriatr Soc. 2019 Oct;67(10):2102-2107. doi: 10.1111/jgs.16024. Epub 2019 Jun 18.


Nonpharmacologic Management of Orthostatic Hypotension in Older People: A Systematic Review. The SENATOR ONTOP Series.

Subbarayan S, Myint PK, Martin KR, Abraha I, Devkota S, O'Mahony D, Cruz-Jentoft AJ, Cherubini A, Soiza RL.

J Am Med Dir Assoc. 2019 Sep;20(9):1065-1073.e3. doi: 10.1016/j.jamda.2019.03.032. Epub 2019 May 17. Review.


Prevalence and documented causes of hyponatraemia among geriatric patients attending a primary care clinic.

Tay CL, Myint PK, Mohazmi M, Soiza RL, Tan MP.

Med J Malaysia. 2019 Apr;74(2):121-127.


The effect of SENATOR (Software ENgine for the Assessment and optimisation of drug and non-drug Therapy in Older peRsons) on incident adverse drug reactions (ADRs) in an older hospital cohort - Trial Protocol.

Lavan AH, O'Mahony D, Gallagher P, Fordham R, Flanagan E, Dahly D, Byrne S, Petrovic M, Gudmundsson A, Samuelsson O, Cherubini A, J Cruz-Jentoft A, Soiza RL, Eustace JA.

BMC Geriatr. 2019 Feb 13;19(1):40. doi: 10.1186/s12877-019-1047-9.


Serum sodium level variability as a prognosticator in older adults.

Barma MA, Soiza RL, Donnan PT, McGilchrist MM, Frost H, Witham MD.

Scand J Clin Lab Invest. 2018 Nov - Dec;78(7-8):632-638. doi: 10.1080/00365513.2018.1543893.


Efficacy of non-pharmacological interventions to treat malnutrition in older persons: A systematic review and meta-analysis. The SENATOR project ONTOP series and MaNuEL knowledge hub project.

Correa-Pérez A, Abraha I, Cherubini A, Collinson A, Dardevet D, de Groot LCPGM, de van der Schueren MAE, Hebestreit A, Hickson M, Jaramillo-Hidalgo J, Lozano-Montoya I, O'Mahony D, Soiza RL, Visser M, Volkert D, Wolters M, Jentoft AJC.

Ageing Res Rev. 2019 Jan;49:27-48. doi: 10.1016/j.arr.2018.10.011. Epub 2018 Nov 2. Review.


Non-pharmacological interventions for the improvement of post-stroke activities of daily living and disability amongst older stroke survivors: A systematic review.

Stewart C, Subbarayan S, Paton P, Gemmell E, Abraha I, Myint PK, O'Mahony D, Cruz-Jentoft AJ, Cherubini A, Soiza RL.

PLoS One. 2018 Oct 4;13(10):e0204774. doi: 10.1371/journal.pone.0204774. eCollection 2018.


Effect of two different participant information sheets on recruitment to a falls trial: An embedded randomised recruitment trial.

Witham MD, Band MM, Price RJG, Fulton RL, Clarke CL, Donnan PT, Soiza RL, Cvoro V.

Clin Trials. 2018 Dec;15(6):551-556. doi: 10.1177/1740774518803558. Epub 2018 Sep 27.


The pale evidence for treatment of iron-deficiency anaemia in older people.

Soiza RL, Donaldson AIC, Myint PK.

Ther Adv Drug Saf. 2018 Jun;9(6):259-261. doi: 10.1177/2042098618769568. Epub 2018 Apr 11. No abstract available.


Incident adverse drug reactions in geriatric inpatients: a multicentred observational study.

Lavan A, Eustace J, Dahly D, Flanagan E, Gallagher P, Cullinane S, Petrovic M, Perehudoff K, Gudmondsson A, Samuelsson Ó, Sverrisdóttir Á, Cherubin A, Dimitri F, Rimland J, Cruz-Jentoft A, Vélez-Díaz-Pallarés M, Lozano Montoya I, Soiza RL, Subbarayan S, O'Mahony D.

Ther Adv Drug Saf. 2018 Jan;9(1):13-23. doi: 10.1177/2042098617736191. Epub 2017 Oct 24.


Management of acute coronary syndromes in older people.

Soiza RL.

Age Ageing. 2018 Jan 1;47(1):2-3. doi: 10.1093/ageing/afx160. No abstract available.


Prevalence and determinants of frailty and associated comorbidities among older Gurkha welfare pensioners in Nepal.

Devkota S, Anderson B, Soiza RL, Myint PK.

Geriatr Gerontol Int. 2017 Dec;17(12):2493-2499. doi: 10.1111/ggi.13113. Epub 2017 Aug 2.


Nonpharmacological interventions to treat physical frailty and sarcopenia in older patients: a systematic overview - the SENATOR Project ONTOP Series.

Lozano-Montoya I, Correa-Pérez A, Abraha I, Soiza RL, Cherubini A, O'Mahony D, Cruz-Jentoft AJ.

Clin Interv Aging. 2017 Apr 24;12:721-740. doi: 10.2147/CIA.S132496. eCollection 2017. Review.


The SENATOR project: developing and trialling a novel software engine to optimize medications and nonpharmacological therapy in older people with multimorbidity and polypharmacy.

Soiza RL, Subbarayan S, Antonio C, Cruz-Jentoft AJ, Petrovic M, Gudmundsson A, O'Mahony D.

Ther Adv Drug Saf. 2017 Mar;8(3):81-85. doi: 10.1177/2042098616675851. Epub 2016 Nov 2. No abstract available.


Systematic review of systematic reviews of non-pharmacological interventions to treat behavioural disturbances in older patients with dementia. The SENATOR-OnTop series.

Abraha I, Rimland JM, Trotta FM, Dell'Aquila G, Cruz-Jentoft A, Petrovic M, Gudmundsson A, Soiza R, O'Mahony D, Guaita A, Cherubini A.

BMJ Open. 2017 Mar 16;7(3):e012759. doi: 10.1136/bmjopen-2016-012759. Review. Erratum in: BMJ Open. 2017 Jul 17;7(7):e012759corr1.


Non-Pharmacological Interventions to Prevent or Treat Delirium in Older Patients: Clinical Practice Recommendations The SENATOR-ONTOP Series.

Abraha I, Rimland JM, Trotta F, Pierini V, Cruz-Jentoft A, Soiza R, O'Mahony D, Cherubini A.

J Nutr Health Aging. 2016;20(9):927-936. Review.


Patterns of Drug Use and Serum Sodium Concentrations in Older Hospitalized Patients: A Latent Class Analysis Approach.

Woodman RJ, Wood KM, Kunnel A, Dedigama M, Pegoli MA, Soiza RL, Mangoni AA.

Drugs Real World Outcomes. 2016 Dec;3(4):383-391.


Effectiveness of Non-Pharmacological Interventions to Prevent Falls in Older People: A Systematic Overview. The SENATOR Project ONTOP Series.

Rimland JM, Abraha I, Dell'Aquila G, Cruz-Jentoft A, Soiza R, Gudmusson A, Petrovic M, O'Mahony D, Todd C, Cherubini A.

PLoS One. 2016 Aug 25;11(8):e0161579. doi: 10.1371/journal.pone.0161579. eCollection 2016. Review.


Addition of sodium criterion to SOAR stroke score.

Adekunle-Olarinde IR, McCall SJ, Barlas RS, Wood AD, Clark AB, Bettencourt-Silva JH, Metcalf AK, Bowles KM, Soiza RL, Potter JF, Myint PK.

Acta Neurol Scand. 2017 May;135(5):553-559. doi: 10.1111/ane.12634. Epub 2016 Jul 10.


Optimal target for blood pressure control - how low should we go?

Soiza RL, Shields L.

J R Coll Physicians Edinb. 2016 Mar;46(1):21-2. doi: 10.4997/JRCPE.2016.106. No abstract available.


Nonpharmacologic Interventions to Prevent Pressure Ulcers in Older Patients: An Overview of Systematic Reviews (The Software ENgine for the Assessment and optimization of drug and non-drug Therapy in Older peRsons [SENATOR] Definition of Optimal Evidence-Based Non-drug Therapies in Older People [ONTOP] Series).

Lozano-Montoya I, Vélez-Díaz-Pallarés M, Abraha I, Cherubini A, Soiza RL, O'Mahony D, Montero-Errasquín B, Correa-Pérez A, Cruz-Jentoft AJ.

J Am Med Dir Assoc. 2016 Apr 1;17(4):370.e1-10. doi: 10.1016/j.jamda.2015.12.091. Epub 2016 Feb 5. Review.


Meta-analysis of Multifactorial Interventions to Prevent Falls of Older Adults in Care Facilities.

Rimland JM, Dell'Aquila G, O'Mahony D, Soiza RL, Cruz-Jentoft A, Abraha I, Cherubini A.

J Am Geriatr Soc. 2015 Sep;63(9):1972-3. doi: 10.1111/jgs.13622. No abstract available.


Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? Study protocol for a randomized controlled trial.

Witham MD, Band MM, Littleford RC, Avenell A, Soiza RL, McMurdo ME, Sumukadas D, Ogston SA, Lamb EJ, Hampson G, McNamee P; BiCARB Study Group.

Trials. 2015 Aug 1;16:326. doi: 10.1186/s13063-015-0843-6.


Hyponatremia predicts mortality after stroke.

Soiza RL, Cumming K, Clark AB, Bettencourt-Silva JH, Metcalf AK, Bowles KM, Potter JF, Myint PK.

Int J Stroke. 2015 Oct;10 Suppl A100:50-5. doi: 10.1111/ijs.12564. Epub 2015 Jul 14.


Efficacy of Non-Pharmacological Interventions to Prevent and Treat Delirium in Older Patients: A Systematic Overview. The SENATOR project ONTOP Series.

Abraha I, Trotta F, Rimland JM, Cruz-Jentoft A, Lozano-Montoya I, Soiza RL, Pierini V, Dessì Fulgheri P, Lattanzio F, O'Mahony D, Cherubini A.

PLoS One. 2015 Jun 10;10(6):e0123090. doi: 10.1371/journal.pone.0123090. eCollection 2015. Review.


Hyponatraemia after fracture is often caused by hypovolaemia, not SIADH.

Cumming K, Soiza RL.

Adv Orthop. 2015;2015:959213. doi: 10.1155/2015/959213. Epub 2015 Feb 24. No abstract available.


Nonpharmacologic Interventions to Heal Pressure Ulcers in Older Patients: An Overview of Systematic Reviews (The SENATOR-ONTOP Series).

Vélez-Díaz-Pallarés M, Lozano-Montoya I, Abraha I, Cherubini A, Soiza RL, O'Mahony D, Montero-Errasquín B, Cruz-Jentoft AJ.

J Am Med Dir Assoc. 2015 Jun 1;16(6):448-69. doi: 10.1016/j.jamda.2015.01.083. Epub 2015 Feb 27. Review.


Systematic review and meta-analysis: what is the evidence for oral iron supplementation in treating anaemia in elderly people?

Tay HS, Soiza RL.

Drugs Aging. 2015 Feb;32(2):149-58. doi: 10.1007/s40266-015-0241-5. Review.


Evidence of and recommendations for non-pharmacological interventions for common geriatric conditions: the SENATOR-ONTOP systematic review protocol.

Abraha I, Cruz-Jentoft A, Soiza RL, O'Mahony D, Cherubini A.

BMJ Open. 2015 Jan 27;5(1):e007488. doi: 10.1136/bmjopen-2014-007488.


Prognosis of hyponatremia in elderly patients with fragility fractures.

Cumming K, McKenzie S, Hoyle GE, Hutchison JD, Soiza RL.

J Clin Med Res. 2015 Jan;7(1):45-51. doi: 10.14740/jocmr1984w. Epub 2014 Oct 16.


Bioelectrical impedance analysis is more accurate than clinical examination in determining the volaemic status of elderly patients with fragility fracture and hyponatraemia.

Cumming K, Hoyle GE, Hutchison JD, Soiza RL.

J Nutr Health Aging. 2014;18(8):744-50. doi: 10.1007/s12603-014-0446-z.


Associations between different measures of anticholinergic drug exposure and Barthel Index in older hospitalized patients.

Bostock CV, Soiza RL, Mangoni AA.

Ther Adv Drug Saf. 2013 Dec;4(6):235-45. doi: 10.1177/2042098613500689.


Minimizing anticholinergic drug prescribing in older hospitalized patients: a full audit cycle.

Tay HS, Soiza RL, Mangoni AA.

Ther Adv Drug Saf. 2014 Jun;5(3):121-8. doi: 10.1177/2042098614523638.


The relationship between total anticholinergic burden (ACB) and early in-patient hospital mortality and length of stay in the oldest old aged 90 years and over admitted with an acute illness.

Kidd AC, Musonda P, Soiza RL, Butchart C, Lunt CJ, Pai Y, Hameed Y, Fox C, Potter JF, Myint PK.

Arch Gerontol Geriatr. 2014 Jul-Aug;59(1):155-61. doi: 10.1016/j.archger.2014.01.006. Epub 2014 Feb 5.


Prevalence, incidence and etiology of hyponatremia in elderly patients with fragility fractures.

Cumming K, Hoyle GE, Hutchison JD, Soiza RL.

PLoS One. 2014 Feb 5;9(2):e88272. doi: 10.1371/journal.pone.0088272. eCollection 2014.


A simple 5-point scoring system, NaURSE (Na+, urea, respiratory rate and shock index in the elderly), predicts in-hospital mortality in oldest old.

Wilson AH, Kidd AC, Skinner J, Musonda P, Pai Y, Lunt CJ, Butchart C, Soiza RL, Potter JF, Myint PK.

Age Ageing. 2014 May;43(3):352-7. doi: 10.1093/ageing/afu002. Epub 2014 Jan 31.


Hyponatremia: Special Considerations in Older Patients.

Soiza RL, Cumming K, Clarke JM, Wood KM, Myint PK.

J Clin Med. 2014 Aug 18;3(3):944-58. doi: 10.3390/jcm3030944. Review.


Memory impairment is associated with serum methylarginines in older adults.

McEvoy M, Schofield P, Smith W, Agho K, Mangoni AA, Soiza RL, Peel R, Attia J.

Curr Alzheimer Res. 2014 Jan;11(1):97-106.


Serum methylarginines and incident depression in a cohort of older adults.

McEvoy MA, Schofield P, Smith W, Agho K, Mangoni AA, Soiza RL, Peel R, Hancock S, Kelly B, Inder K, Carru C, Zinellu A, Attia J.

J Affect Disord. 2013 Nov;151(2):493-9. doi: 10.1016/j.jad.2013.06.033. Epub 2013 Aug 7.


Serum methylarginines and spirometry-measured lung function in older adults.

McEvoy MA, Schofield PW, Smith WT, Agho K, Mangoni AA, Soiza RL, Peel R, Hancock SJ, Carru C, Zinellu A, Attia JR.

PLoS One. 2013 May 15;8(5):e58390. doi: 10.1371/journal.pone.0058390. Print 2013.


Asymmetric dimethylarginine: a possible link between vascular disease and dementia.

Asif M, Soiza RL, McEvoy M, Mangoni AA.

Curr Alzheimer Res. 2013 May 1;10(4):347-56. Review.


Evidence of net benefit of proton pump inhibitors with clopidogrel is lacking in older patients.

Witham MD, Soiza R, Logan I.

BMJ. 2012 Sep 4;345:e5849; author reply e5852. doi: 10.1136/bmj.e5849. No abstract available.


Identification of possible determinants of inpatient mortality using Classification and Regression Tree (CART) analysis in hospitalized oldest old patients.

Butchart C, Ismailoglu F, Myint PK, Musonda P, Lunt CJ, Pai Y, Soiza RL, Rayward-Smith VJ.

Arch Gerontol Geriatr. 2013 Jan-Feb;56(1):188-91. doi: 10.1016/j.archger.2012.07.005. Epub 2012 Aug 9.


Anticholinergic drugs and functional outcomes in older patients undergoing orthopaedic rehabilitation.

Koshoedo S, Soiza RL, Purkayastha R, Mangoni AA.

Am J Geriatr Pharmacother. 2012 Aug;10(4):251-7. doi: 10.1016/j.amjopharm.2012.06.003. Epub 2012 Jul 13.


Inappropriate prescribing of proton pump inhibitors in older patients: effects of an educational strategy.

Hamzat H, Sun H, Ford JC, Macleod J, Soiza RL, Mangoni AA.

Drugs Aging. 2012 Aug 1;29(8):681-90. doi: 10.2165/11632700-000000000-00000.


The effect of hearing augmentation on cognitive assessment scales at admission to hospital.

MacDonald AA, Joyson A, Lee R, Seymour DG, Soiza RL.

Am J Geriatr Psychiatry. 2012 Apr;20(4):355-61. doi: 10.1097/JGP.0b013e3182107e88.


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