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Items: 32


A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies.

Karch CM, Kao AW, Karydas A, Onanuga K, Martinez R, Argouarch A, Wang C, Huang C, Sohn PD, Bowles KR, Spina S, Silva MC, Marsh JA, Hsu S, Pugh DA, Ghoshal N, Norton J, Huang Y, Lee SE, Seeley WW, Theofilas P, Grinberg LT, Moreno F, McIlroy K, Boeve BF, Cairns NJ, Crary JF, Haggarty SJ, Ichida JK, Kosik KS, Miller BL, Gan L, Goate AM, Temple S; Tau Consortium Stem Cell Group.

Stem Cell Reports. 2019 Nov 12;13(5):939-955. doi: 10.1016/j.stemcr.2019.09.006. Epub 2019 Oct 17.


Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.

Sohn PD, Huang CT, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok SA, Freilich R, Baik J, He M, Gong S, Roberson ED, Karch CM, Gestwicki JE, Xu K, Kosik KS, Gan L.

Neuron. 2019 Nov 6;104(3):458-470.e5. doi: 10.1016/j.neuron.2019.08.008. Epub 2019 Sep 18.


Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions.

Melton EM, Li H, Benson J, Sohn P, Huang LH, Song BL, Li BL, Chang CCY, Chang TY.

J Biol Chem. 2019 Oct 25;294(43):15836-15849. doi: 10.1074/jbc.RA119.010564. Epub 2019 Sep 8.


Identification of functional missense single-nucleotide polymorphisms in TNFAIP3 in a predominantly Hispanic population.

Zhang B, Naomi Nakamura B, Perlman A, Alipour O, Abbasi SQ, Sohn P, Gulati A, Moore G, Hwang C, Sheibani S, Zarchy T, Shao L.

J Clin Transl Sci. 2018 Dec;2(6):350-355. doi: 10.1017/cts.2019.3. Epub 2019 May 14.


Prg4 prevents osteoarthritis induced by dominant-negative interference of TGF-ß signaling in mice.

Chavez RD, Sohn P, Serra R.

PLoS One. 2019 Jan 10;14(1):e0210601. doi: 10.1371/journal.pone.0210601. eCollection 2019.


Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic β cell.

Yamamoto WR, Bone RN, Sohn P, Syed F, Reissaus CA, Mosley AL, Wijeratne AB, True JD, Tong X, Kono T, Evans-Molina C.

J Biol Chem. 2019 Jan 4;294(1):168-181. doi: 10.1074/jbc.RA118.005683. Epub 2018 Nov 12.


Impaired Store-Operated Calcium Entry and STIM1 Loss Lead to Reduced Insulin Secretion and Increased Endoplasmic Reticulum Stress in the Diabetic β-Cell.

Kono T, Tong X, Taleb S, Bone RN, Iida H, Lee CC, Sohn P, Gilon P, Roe MW, Evans-Molina C.

Diabetes. 2018 Nov;67(11):2293-2304. doi: 10.2337/db17-1351. Epub 2018 Aug 21.


SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.

Min SW, Sohn PD, Li Y, Devidze N, Johnson JR, Krogan NJ, Masliah E, Mok SA, Gestwicki JE, Gan L.

J Neurosci. 2018 Apr 11;38(15):3680-3688. doi: 10.1523/JNEUROSCI.2369-17.2018. Epub 2018 Mar 14.


Myeloid-specific Acat1 ablation attenuates inflammatory responses in macrophages, improves insulin sensitivity, and suppresses diet-induced obesity.

Huang LH, Melton EM, Li H, Sohn P, Jung D, Tsai CY, Ma T, Sano H, Ha H, Friedline RH, Kim JK, Usherwood E, Chang CCY, Chang TY.

Am J Physiol Endocrinol Metab. 2018 Sep 1;315(3):E340-E356. doi: 10.1152/ajpendo.00174.2017. Epub 2018 Mar 13.


Fracture Resistance of CAD/CAM-Fabricated Lithium Disilicate MOD Inlays and Onlays with Various Cavity Preparation Designs.

Yoon HI, Sohn PJ, Jin S, Elani H, Lee SJ.

J Prosthodont. 2019 Feb;28(2):e524-e529. doi: 10.1111/jopr.12787. Epub 2018 Mar 13.


Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening.

Wang C, Ward ME, Chen R, Liu K, Tracy TE, Chen X, Xie M, Sohn PD, Ludwig C, Meyer-Franke A, Karch CM, Ding S, Gan L.

Stem Cell Reports. 2017 Oct 10;9(4):1221-1233. doi: 10.1016/j.stemcr.2017.08.019. Epub 2017 Sep 28.


Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.

Sohn PD, Tracy TE, Son HI, Zhou Y, Leite RE, Miller BL, Seeley WW, Grinberg LT, Gan L.

Mol Neurodegener. 2016 Jun 29;11(1):47. doi: 10.1186/s13024-016-0109-0.


Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.

Tracy TE, Sohn PD, Minami SS, Wang C, Min SW, Li Y, Zhou Y, Le D, Lo I, Ponnusamy R, Cong X, Schilling B, Ellerby LM, Huganir RL, Gan L.

Neuron. 2016 Apr 20;90(2):245-60. doi: 10.1016/j.neuron.2016.03.005. Epub 2016 Mar 31.


MEPE Localization in the Craniofacial Complex and Function in Tooth Dentin Formation.

Gullard A, Gluhak-Heinrich J, Papagerakis S, Sohn P, Unterbrink A, Chen S, MacDougall M.

J Histochem Cytochem. 2016 Apr;64(4):224-36. doi: 10.1369/0022155416635569. Epub 2016 Feb 29.


Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression.

Huang LH, Melton EM, Li H, Sohn P, Rogers MA, Mulligan-Kehoe MJ, Fiering SN, Hickey WF, Chang CC, Chang TY.

J Biol Chem. 2016 Mar 18;291(12):6232-44. doi: 10.1074/jbc.M116.713818. Epub 2016 Jan 21.


Reduced Dentin Matrix Protein Expression in Camurati-Engelmann Disease Transgenic Mouse Model.

Gullard A, Croney CM, Wu X, Mamaeva O, Sohn P, Cao X, MacDougall M.

J Cell Physiol. 2016 May;231(5):1106-13. doi: 10.1002/jcp.25207. Epub 2015 Dec 29.


Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.

Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, Johnson J, Krogan N, Shamloo M, Gestwicki J, Masliah E, Verdin E, Gan L.

Nat Med. 2015 Oct;21(10):1154-62. doi: 10.1038/nm.3951. Epub 2015 Sep 21.


SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.

Cho SH, Chen JA, Sayed F, Ward ME, Gao F, Nguyen TA, Krabbe G, Sohn PD, Lo I, Minami S, Devidze N, Zhou Y, Coppola G, Gan L.

J Neurosci. 2015 Jan 14;35(2):807-18. doi: 10.1523/JNEUROSCI.2939-14.2015.


Matrix metalloproteinase expression in keratocystic odontogenic tumors and primary cells.

Amm HM, Casimir MD, Clark DB, Sohn P, MacDougall M.

Connect Tissue Res. 2014 Aug;55 Suppl 1:97-101. doi: 10.3109/03008207.2014.923875.


Sirtuins in neurodegenerative diseases: an update on potential mechanisms.

Min SW, Sohn PD, Cho SH, Swanson RA, Gan L.

Front Aging Neurosci. 2013 Sep 25;5:53. doi: 10.3389/fnagi.2013.00053. Review.


WNT5A inhibits metastasis and alters splicing of Cd44 in breast cancer cells.

Jiang W, Crossman DK, Mitchell EH, Sohn P, Crowley MR, Serra R.

PLoS One. 2013;8(3):e58329. doi: 10.1371/journal.pone.0058329. Epub 2013 Mar 6.


Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.

Grinberg LT, Wang X, Wang C, Sohn PD, Theofilas P, Sidhu M, Arevalo JB, Heinsen H, Huang EJ, Rosen H, Miller BL, Gan L, Seeley WW.

Acta Neuropathol. 2013 Apr;125(4):581-93. doi: 10.1007/s00401-013-1080-2. Epub 2013 Jan 31.


Altered responsiveness to TGF-β results in reduced Papss2 expression and alterations in the biomechanical properties of mouse articular cartilage.

Ramaswamy G, Sohn P, Eberhardt A, Serra R.

Arthritis Res Ther. 2012 Mar 6;14(2):R49. doi: 10.1186/ar3762.


Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc.

Sohn P, Cox M, Chen D, Serra R.

BMC Dev Biol. 2010 Mar 9;10:29. doi: 10.1186/1471-213X-10-29.


PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland development.

Chan CB, Liu X, Ensslin MA, Dillehay DL, Ormandy CJ, Sohn P, Serra R, Ye K.

EMBO J. 2010 Mar 3;29(5):956-68. doi: 10.1038/emboj.2009.406. Epub 2010 Jan 14.


Nurse practitioner knowledge of complementary alternative health care: foundation for practice.

Sohn PM, Loveland Cook CA.

J Adv Nurs. 2002 Jul;39(1):9-16.


Developmental and TGF-beta-mediated regulation of Ank mRNA expression in cartilage and bone.

Sohn P, Crowley M, Slattery E, Serra R.

Osteoarthritis Cartilage. 2002 Jun;10(6):482-90.


TGFbeta2 mediates the effects of hedgehog on hypertrophic differentiation and PTHrP expression.

Alvarez J, Sohn P, Zeng X, Doetschman T, Robbins DJ, Serra R.

Development. 2002 Apr;129(8):1913-24.


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