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Items: 1 to 50 of 482

1.

MITF controls the TCA cycle to modulate the melanoma hypoxia response.

Louphrasitthiphol P, Ledaki I, Chauhan J, Falletta P, Siddaway R, Buffa FM, Mole DR, Soga T, Goding CR.

Pigment Cell Melanoma Res. 2019 Jun 17. doi: 10.1111/pcmr.12802. [Epub ahead of print]

PMID:
31207090
2.

Metabolic adaptation to glycolysis is a basic defense mechanism of macrophages for Mycobacterium tuberculosis infection.

Osada-Oka M, Goda N, Saiga H, Yamamoto M, Takeda K, Ozeki Y, Yamaguchi T, Soga T, Tateishi Y, Miura K, Okuzaki D, Kobayashi K, Matsumoto S.

Int Immunol. 2019 Jun 14. pii: dxz048. doi: 10.1093/intimm/dxz048. [Epub ahead of print]

PMID:
31201418
3.

Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer.

Yachida S, Mizutani S, Shiroma H, Shiba S, Nakajima T, Sakamoto T, Watanabe H, Masuda K, Nishimoto Y, Kubo M, Hosoda F, Rokutan H, Matsumoto M, Takamaru H, Yamada M, Matsuda T, Iwasaki M, Yamaji T, Yachida T, Soga T, Kurokawa K, Toyoda A, Ogura Y, Hayashi T, Hatakeyama M, Nakagama H, Saito Y, Fukuda S, Shibata T, Yamada T.

Nat Med. 2019 Jun;25(6):968-976. doi: 10.1038/s41591-019-0458-7. Epub 2019 Jun 6.

PMID:
31171880
4.

Quinolinic Acid and Nuclear Factor Erythroid 2-Related Factor 2 in Depression: Role in Neuroprogression.

Bansal Y, Singh R, Parhar I, Kuhad A, Soga T.

Front Pharmacol. 2019 May 21;10:452. doi: 10.3389/fphar.2019.00452. eCollection 2019. Review.

5.

Clinical features and new diagnostic criteria for the syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis.

Takeuchi Y, Shigemura T, Kobayashi N, Nagumo H, Furumoto M, Ogasawara K, Fujii H, Takizawa M, Soga T, Matoba H, Masumoto J, Fukushima K, Migita K, Ojima T, Umeda Y, Agematsu K.

Int J Rheum Dis. 2019 May 27. doi: 10.1111/1756-185X.13610. [Epub ahead of print]

PMID:
31131563
6.

Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease.

Kikuchi K, Saigusa D, Kanemitsu Y, Matsumoto Y, Thanai P, Suzuki N, Mise K, Yamaguchi H, Nakamura T, Asaji K, Mukawa C, Tsukamoto H, Sato T, Oikawa Y, Iwasaki T, Oe Y, Tsukimi T, Fukuda NN, Ho HJ, Nanto-Hara F, Ogura J, Saito R, Nagao S, Ohsaki Y, Shimada S, Suzuki T, Toyohara T, Mishima E, Shima H, Akiyama Y, Akiyama Y, Ichijo M, Matsuhashi T, Matsuo A, Ogata Y, Yang CC, Suzuki C, Breeggemann MC, Heymann J, Shimizu M, Ogawa S, Takahashi N, Suzuki T, Owada Y, Kure S, Mano N, Soga T, Wada T, Kopp JB, Fukuda S, Hozawa A, Yamamoto M, Ito S, Wada J, Tomioka Y, Abe T.

Nat Commun. 2019 Apr 23;10(1):1835. doi: 10.1038/s41467-019-09735-4.

7.

Autophagy regulates lipid metabolism through selective turnover of NCoR1.

Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, Okuda S, Lee HC, Ikeda K, Kanegae Y, Saito I, Auwerx J, Motohashi H, Suematsu M, Soga T, Yokomizo T, Waguri S, Mizushima N, Komatsu M.

Nat Commun. 2019 Apr 5;10(1):1567. doi: 10.1038/s41467-019-08829-3.

8.

Synthetic miR-143 Exhibited an Anti-Cancer Effect via the Downregulation of K-RAS Networks of Renal Cell Cancer Cells In Vitro and In Vivo.

Takai T, Tsujino T, Yoshikawa Y, Inamoto T, Sugito N, Kuranaga Y, Heishima K, Soga T, Hayashi K, Miyata K, Kataoka K, Azuma H, Akao Y.

Mol Ther. 2019 May 8;27(5):1017-1027. doi: 10.1016/j.ymthe.2019.03.004. Epub 2019 Mar 13.

9.

Axis elongation during Xenopus tail-bud stage is regulated by GABA expressed in the anterior-to-mid neural tube.

Furukawa T, Yamasaki Y, Hara Y, Otsuki C, Maki H, Soga T, Moriyama Y, Kuroda H.

Int J Dev Biol. 2019;63(1-2):37-43. doi: 10.1387/ijdb.180384hk.

PMID:
30919914
10.

Metabolome profiling of various seaweed species discriminates between brown, red, and green algae.

Hamid SS, Wakayama M, Ichihara K, Sakurai K, Ashino Y, Kadowaki R, Soga T, Tomita M.

Planta. 2019 Jun;249(6):1921-1947. doi: 10.1007/s00425-019-03134-1. Epub 2019 Mar 19.

PMID:
30891648
11.

Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.

Valli A, Morotti M, Zois CE, Albers PK, Soga T, Feldinger K, Fischer R, Frejno M, McIntyre A, Bridges E, Haider S, Buffa FM, Baban D, Rodriguez M, Yanes O, Whittington HJ, Lake HA, Zervou S, Lygate CA, Kessler BM, Harris AL.

Mol Cancer Res. 2019 Mar 18. doi: 10.1158/1541-7786.MCR-18-0315. [Epub ahead of print]

PMID:
30885992
12.

Silicon Nanowire Heterojunction Solar Cells with an Al2O3 Passivation Film Fabricated by Atomic Layer Deposition.

Kato S, Kurokawa Y, Gotoh K, Soga T.

Nanoscale Res Lett. 2019 Mar 15;14(1):99. doi: 10.1186/s11671-019-2930-1.

13.

Efficacy of primary treatment with immunoglobulin plus ciclosporin for prevention of coronary artery abnormalities in patients with Kawasaki disease predicted to be at increased risk of non-response to intravenous immunoglobulin (KAICA): a randomised controlled, open-label, blinded-endpoints, phase 3 trial.

Hamada H, Suzuki H, Onouchi Y, Ebata R, Terai M, Fuse S, Okajima Y, Kurotobi S, Hirai K, Soga T, Ishiguchi Y, Okuma Y, Takada N, Yanai M, Sato J, Nakayashiro M, Ayusawa M, Yamamoto E, Nomura Y, Hashimura Y, Ouchi K, Masuda H, Takatsuki S, Hirono K, Ariga T, Higaki T, Otsuki A, Terauchi M, Aoyagi R, Sato T, Fujii Y, Fujiwara T, Hanaoka H, Hata A; KAICA trial Investigators.

Lancet. 2019 Mar 16;393(10176):1128-1137. doi: 10.1016/S0140-6736(18)32003-8. Epub 2019 Mar 7. Erratum in: Lancet. 2019 Mar 30;393(10178):1298. Lancet. 2019 Apr 13;393(10180):1504.

PMID:
30853151
14.

Role of smooth muscle cell p53 in pulmonary arterial hypertension.

Wakasugi T, Shimizu I, Yoshida Y, Hayashi Y, Ikegami R, Suda M, Katsuumi G, Nakao M, Hoyano M, Kashimura T, Nakamura K, Ito H, Nojiri T, Soga T, Minamino T.

PLoS One. 2019 Feb 26;14(2):e0212889. doi: 10.1371/journal.pone.0212889. eCollection 2019.

15.

Social Defeat Stress Decreases mRNA for Monoamine Oxidase A and Increases 5-HT Turnover in the Brain of Male Nile Tilapia (Oreochromis niloticus).

Higuchi Y, Soga T, Parhar IS.

Front Pharmacol. 2019 Jan 9;9:1549. doi: 10.3389/fphar.2018.01549. eCollection 2018.

16.

Expression of RING Finger Protein 38 in Serotonergic Neurons in the Brain of Nile Tilapia, Oreochromis niloticus.

Cham KL, Soga T, Parhar IS.

Front Neuroanat. 2018 Dec 6;12:109. doi: 10.3389/fnana.2018.00109. eCollection 2018.

17.

A Metabologenomic Approach Reveals Changes in the Intestinal Environment of Mice Fed on American Diet.

Ishii C, Nakanishi Y, Murakami S, Nozu R, Ueno M, Hioki K, Aw W, Hirayama A, Soga T, Ito M, Tomita M, Fukuda S.

Int J Mol Sci. 2018 Dec 17;19(12). pii: E4079. doi: 10.3390/ijms19124079.

18.

Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.

Nishimura T, Nakata A, Chen X, Nishi K, Meguro-Horike M, Sasaki S, Kita K, Horike SI, Saitoh K, Kato K, Igarashi K, Murayama T, Kohno S, Takahashi C, Mukaida N, Yano S, Soga T, Tojo A, Gotoh N.

Oncogene. 2019 Apr;38(14):2464-2481. doi: 10.1038/s41388-018-0589-1. Epub 2018 Dec 7.

PMID:
30532069
19.

Metabolomics Platform with Capillary Electrophoresis Coupled with High-Resolution Mass Spectrometry for Plasma Analysis.

Sasaki K, Sagawa H, Suzuki M, Yamamoto H, Tomita M, Soga T, Ohashi Y.

Anal Chem. 2019 Jan 15;91(2):1295-1301. doi: 10.1021/acs.analchem.8b02994. Epub 2018 Dec 24.

PMID:
30500154
20.

Effects of inter-day and intra-day variation on salivary metabolomic profiles.

Kawanishi N, Hoshi N, Masahiro S, Enomoto A, Ota S, Kaneko M, Soga T, Tomita M, Kimoto K.

Clin Chim Acta. 2019 Feb;489:41-48. doi: 10.1016/j.cca.2018.11.030. Epub 2018 Nov 24.

PMID:
30481500
21.

GLUT6 is a lysosomal transporter that is regulated by inflammatory stimuli and modulates glycolysis in macrophages.

Maedera S, Mizuno T, Ishiguro H, Ito T, Soga T, Kusuhara H.

FEBS Lett. 2019 Jan;593(2):195-208. doi: 10.1002/1873-3468.13298. Epub 2018 Dec 4.

PMID:
30431159
22.

Synthesis of Ge1-xSnx Alloy Thin Films by Rapid Thermal Annealing of Sputtered Ge/Sn/Ge Layers on Si Substrates.

Mahmodi H, Hashim MR, Soga T, Alrokayan S, Khan HA, Rusop M.

Materials (Basel). 2018 Nov 12;11(11). pii: E2248. doi: 10.3390/ma11112248.

23.

Perioperative serum and urine metabolome analyses in patients with hepatocellular carcinoma undergoing partial hepatectomy.

Kajiura D, Yamanaka-Okumura H, Hirayama A, Tatano H, Endo K, Honma M, Igarashi K, Shoji F, Ikeda S, Yamaguchi N, Katayama T, Morine Y, Imura S, Utsunomiya T, Soga T, Tomita M, Shimada M.

Nutrition. 2019 Feb;58:110-119. doi: 10.1016/j.nut.2018.06.002. Epub 2018 Aug 7.

PMID:
30391689
24.

Pyruvate dehydrogenase activation precedes the down-regulation of fatty acid oxidation in monocrotaline-induced myocardial toxicity in mice.

Nakai G, Shimura D, Uesugi K, Kajimura I, Jiao Q, Kusakari Y, Soga T, Goda N, Minamisawa S.

Heart Vessels. 2019 Mar;34(3):545-555. doi: 10.1007/s00380-018-1293-3. Epub 2018 Nov 1.

PMID:
30386918
25.

Metabolic Characterization of Antifolate Responsiveness and Non-responsiveness in Malignant Pleural Mesothelioma Cells.

Sato Y, Matsuda S, Maruyama A, Nakayama J, Miyashita T, Udagawa H, Umemura S, Yanagihara K, Ochiai A, Tomita M, Soga T, Tsuchihara K, Makinoshima H.

Front Pharmacol. 2018 Oct 12;9:1129. doi: 10.3389/fphar.2018.01129. eCollection 2018.

26.

Percutaneous pulmonary debanding for an infant complicated by spontaneously closing muscular ventricular septal defect: A case report and in vitro study.

Terazawa A, Fujii T, Sasaki T, Asada D, Tarui S, Miyahara Y, Ishino K, Soga T, Tomita H.

J Cardiol Cases. 2017 Nov 6;17(1):16-20. doi: 10.1016/j.jccase.2017.08.012. eCollection 2018 Jan.

27.

SRSF3, a Splicer of the PKM Gene, Regulates Cell Growth and Maintenance of Cancer-Specific Energy Metabolism in Colon Cancer Cells.

Kuranaga Y, Sugito N, Shinohara H, Tsujino T, Taniguchi K, Komura K, Ito Y, Soga T, Akao Y.

Int J Mol Sci. 2018 Oct 2;19(10). pii: E3012. doi: 10.3390/ijms19103012.

28.

Beta-galactosidase-responsive synthetic biomarker for targeted tumor detection.

Nishihara T, Kuno S, Nonaka H, Tabata S, Saito N, Fukuda S, Tomita M, Sando S, Soga T.

Chem Commun (Camb). 2018 Oct 16;54(83):11745-11748. doi: 10.1039/c8cc06068a.

PMID:
30276401
29.

A Metabolomic-Based Evaluation of the Role of Commensal Microbiota throughout the Gastrointestinal Tract in Mice.

Yamamoto Y, Nakanishi Y, Murakami S, Aw W, Tsukimi T, Nozu R, Ueno M, Hioki K, Nakahigashi K, Hirayama A, Sugimoto M, Soga T, Ito M, Tomita M, Fukuda S.

Microorganisms. 2018 Sep 29;6(4). pii: E101. doi: 10.3390/microorganisms6040101.

30.

Potential Roles of microRNAs in the Regulation of Monoamine Oxidase A in the Brain.

Higuchi Y, Soga T, Parhar IS.

Front Mol Neurosci. 2018 Sep 14;11:339. doi: 10.3389/fnmol.2018.00339. eCollection 2018. Review.

31.

Trans-omic Analysis Reveals Selective Responses to Induced and Basal Insulin across Signaling, Transcriptional, and Metabolic Networks.

Kawata K, Hatano A, Yugi K, Kubota H, Sano T, Fujii M, Tomizawa Y, Kokaji T, Tanaka KY, Uda S, Suzuki Y, Matsumoto M, Nakayama KI, Saitoh K, Kato K, Ueno A, Ohishi M, Hirayama A, Soga T, Kuroda S.

iScience. 2018 Sep 28;7:212-229. doi: 10.1016/j.isci.2018.07.022. Epub 2018 Sep 10.

32.

Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity.

Ikegami R, Shimizu I, Sato T, Yoshida Y, Hayashi Y, Suda M, Katsuumi G, Li J, Wakasugi T, Minokoshi Y, Okamoto S, Hinoi E, Nielsen S, Jespersen NZ, Scheele C, Soga T, Minamino T.

Cell Rep. 2018 Sep 11;24(11):2827-2837.e5. doi: 10.1016/j.celrep.2018.08.024.

33.

Effect of storage conditions on salivary polyamines quantified via liquid chromatography-mass spectrometry.

Tomita A, Mori M, Hiwatari K, Yamaguchi E, Itoi T, Sunamura M, Soga T, Tomita M, Sugimoto M.

Sci Rep. 2018 Aug 13;8(1):12075. doi: 10.1038/s41598-018-30482-x.

34.

Static balloon atrial septostomy for the purpose of left heart intervention in postoperative adult CHD.

Fujii T, Tomita H, Hata Y, Sasaki T, Asada D, Tarui S, Miyahara Y, Ishino K, Soga T.

Cardiol Young. 2018 Oct;28(10):1116-1121. doi: 10.1017/S1047951118001063. Epub 2018 Jul 11.

PMID:
29991378
35.

Differences in peritoneal solute transport rates in peritoneal dialysis.

Asano M, Ishii T, Hirayama A, Mizuno M, Suzuki Y, Sakata F, Akiyama SI, Maruyama S, Soga T, Kinashi H, Katsuno T, Ito Y.

Clin Exp Nephrol. 2019 Jan;23(1):122-134. doi: 10.1007/s10157-018-1611-1. Epub 2018 Jul 2.

PMID:
29968125
36.

Metabolomics-based profiles predictive of low bone mass in menopausal women.

Miyamoto T, Hirayama A, Sato Y, Koboyashi T, Katsuyama E, Kanagawa H, Fujie A, Morita M, Watanabe R, Tando T, Miyamoto K, Tsuji T, Funayama A, Soga T, Tomita M, Nakamura M, Matsumoto M.

Bone Rep. 2018 Jun 18;9:11-18. doi: 10.1016/j.bonr.2018.06.004. eCollection 2018 Dec.

37.

Low tumor glutathione level as a sensitivity marker for glutamate-cysteine ligase inhibitors.

Nishizawa S, Araki H, Ishikawa Y, Kitazawa S, Hata A, Soga T, Hara T.

Oncol Lett. 2018 Jun;15(6):8735-8743. doi: 10.3892/ol.2018.8447. Epub 2018 Apr 10.

38.

Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation.

Baba M, Endoh M, Ma W, Toyama H, Hirayama A, Nishikawa K, Takubo K, Hano H, Hasumi H, Umemoto T, Hashimoto M, Irie N, Esumi C, Kataoka M, Nakagata N, Soga T, Yao M, Kamba T, Minami T, Ishii M, Suda T.

J Bone Miner Res. 2018 Oct;33(10):1785-1798. doi: 10.1002/jbmr.3477. Epub 2018 Jun 26.

39.

Changes of liver metabolites following hepatectomy with ischemia reperfusion towards liver regeneration.

Saito Y, Morine Y, Iwahashi S, Ikemoto T, Imura S, Yamanaka-Okumura H, Hirayama A, Soga T, Tomita M, Shimada M.

Ann Gastroenterol Surg. 2018 Jan 30;2(3):204-211. doi: 10.1002/ags3.12058. eCollection 2018 May.

40.

Thymidine catabolism promotes NADPH oxidase-derived reactive oxygen species (ROS) signalling in KB and yumoto cells.

Tabata S, Yamamoto M, Goto H, Hirayama A, Ohishi M, Kuramoto T, Mitsuhashi A, Ikeda R, Haraguchi M, Kawahara K, Shinsato Y, Minami K, Saijo A, Toyoda Y, Hanibuchi M, Nishioka Y, Sone S, Esumi H, Tomita M, Soga T, Furukawa T, Akiyama SI.

Sci Rep. 2018 Apr 30;8(1):6760. doi: 10.1038/s41598-018-25189-y.

41.

Identification of Transmembrane Protease Serine 2 and Forkhead Box A1 As the Potential Bisphenol A Responsive Genes in the Neonatal Male Rat Brain.

Ubuka T, Moriya S, Soga T, Parhar I.

Front Endocrinol (Lausanne). 2018 Mar 28;9:139. doi: 10.3389/fendo.2018.00139. eCollection 2018.

42.

Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice.

Doke T, Ishimoto T, Hayasaki T, Ikeda S, Hasebe M, Hirayama A, Soga T, Kato N, Kosugi T, Tsuboi N, Lanaspa MA, Johnson RJ, Kadomatsu K, Maruyama S.

Metabolism. 2018 Aug;85:161-170. doi: 10.1016/j.metabol.2018.03.020. Epub 2018 Mar 29.

PMID:
29604362
43.

PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.

Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N.

Cancer Cell. 2018 Mar 12;33(3):355-367.e7. doi: 10.1016/j.ccell.2018.02.004.

44.

Urinary Polyamine Biomarker Panels with Machine-Learning Differentiated Colorectal Cancers, Benign Disease, and Healthy Controls.

Nakajima T, Katsumata K, Kuwabara H, Soya R, Enomoto M, Ishizaki T, Tsuchida A, Mori M, Hiwatari K, Soga T, Tomita M, Sugimoto M.

Int J Mol Sci. 2018 Mar 7;19(3). pii: E756. doi: 10.3390/ijms19030756.

45.

Microhomology-assisted scarless genome editing in human iPSCs.

Kim SI, Matsumoto T, Kagawa H, Nakamura M, Hirohata R, Ueno A, Ohishi M, Sakuma T, Soga T, Yamamoto T, Woltjen K.

Nat Commun. 2018 Mar 5;9(1):939. doi: 10.1038/s41467-018-03044-y.

46.

Development of a sheathless CE-ESI-MS interface.

Hirayama A, Abe H, Yamaguchi N, Tabata S, Tomita M, Soga T.

Electrophoresis. 2018 Jun;39(11):1382-1389. doi: 10.1002/elps.201800017. Epub 2018 Mar 25.

PMID:
29493797
47.

Brain Beta-Catenin Signalling During Stress and Depression.

Teo CH, Soga T, Parhar IS.

Neurosignals. 2018;26(1):31-42. doi: 10.1159/000487764. Epub 2018 Feb 22. Review.

48.

Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors.

Oshima K, Saiki N, Tanaka M, Imamura H, Niwa A, Tanimura A, Nagahashi A, Hirayama A, Okita K, Hotta A, Kitayama S, Osawa M, Kaneko S, Watanabe A, Asaka I, Fujibuchi W, Imai K, Yabe H, Kamachi Y, Hara J, Kojima S, Tomita M, Soga T, Noma T, Nonoyama S, Nakahata T, Saito MK.

Biochem Biophys Res Commun. 2018 Mar 4;497(2):719-725. doi: 10.1016/j.bbrc.2018.02.139. Epub 2018 Feb 17.

49.

Elevated Polyamines in Saliva of Pancreatic Cancer.

Asai Y, Itoi T, Sugimoto M, Sofuni A, Tsuchiya T, Tanaka R, Tonozuka R, Honjo M, Mukai S, Fujita M, Yamamoto K, Matsunami Y, Kurosawa T, Nagakawa Y, Kaneko M, Ota S, Kawachi S, Shimazu M, Soga T, Tomita M, Sunamura M.

Cancers (Basel). 2018 Feb 5;10(2). pii: E43. doi: 10.3390/cancers10020043.

50.

Comparative analysis of cerebrospinal fluid metabolites in Alzheimer's disease and idiopathic normal pressure hydrocephalus in a Japanese cohort.

Nagata Y, Hirayama A, Ikeda S, Shirahata A, Shoji F, Maruyama M, Kayano M, Bundo M, Hattori K, Yoshida S, Goto YI, Urakami K, Soga T, Ozaki K, Niida S.

Biomark Res. 2018 Jan 22;6:5. doi: 10.1186/s40364-018-0119-x. eCollection 2018.

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