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Items: 46

1.

SPECT perfusion abnormality associated with arrhythmogenic right ventricular cardiomyopathy.

Hardebeck C, Wada A, Sofowora G.

J Nucl Cardiol. 2018 Jun;25(3):1044-1047. doi: 10.1007/s12350-017-0783-5. Epub 2017 Jan 17. No abstract available.

PMID:
28097477
2.

Genetic variation in the alpha1B-adrenergic receptor and vascular response.

Adefurin A, Ghimire LV, Kohli U, Muszkat M, Sofowora GG, Li C, Levinson RT, Paranjape SY, Stein CM, Kurnik D.

Pharmacogenomics J. 2017 Jul;17(4):366-371. doi: 10.1038/tpj.2016.29. Epub 2016 Apr 19.

3.

Genetic variation in alpha2-adrenoreceptors and heart rate recovery after exercise.

Kohli U, Diedrich A, Kannankeril PJ, Muszkat M, Sofowora GG, Hahn MK, English BA, Blakely RD, Stein CM, Kurnik D.

Physiol Genomics. 2015 Sep;47(9):400-6. doi: 10.1152/physiolgenomics.00124.2014. Epub 2015 Jun 9.

4.

Genetic variation in the α1A-adrenergic receptor and phenylephrine-mediated venoconstriction.

Adefurin A, Ghimire LV, Kohli U, Muszkat M, Sofowora GG, Li C, Paranjape SY, Stein CM, Kurnik D.

Pharmacogenomics J. 2015 Aug;15(4):310-5. doi: 10.1038/tpj.2014.69. Epub 2014 Nov 25.

5.

Type of Valvular Heart Disease Requiring Surgery in the 21st Century: Mortality and Length-of-Stay Related to Surgery.

Boudoulas KD, Ravi Y, Garcia D, Saini U, Sofowora GG, Gumina RJ, Sai-Sudhakar CB.

Open Cardiovasc Med J. 2013 Sep 4;7:104-9. doi: 10.2174/1874192420130902001. eCollection 2013.

6.

Variation in the α(2A) adrenoceptor gene and the effect of dexmedetomidine on plasma insulin and glucose.

Ghimire LV, Muszkat M, Sofowora GG, Scheinin M, Wood AJ, Stein CM, Kurnik D.

Pharmacogenet Genomics. 2013 Sep;23(9):479-86. doi: 10.1097/FPC.0b013e3283642f93.

7.

Blacks have a greater sensitivity to α1-adrenoceptor-mediated venoconstriction compared with whites.

Adefurin A, Ghimire LV, Kohli U, Muszkat M, Sofowora GG, Paranjape SY, Stein CM, Kurnik D.

Hypertension. 2013 Apr;61(4):915-20. doi: 10.1161/HYPERTENSIONAHA.111.00854. Epub 2013 Feb 11.

8.

A polymorphism in the protein kinase C gene PRKCB is associated with α2-adrenoceptor-mediated vasoconstriction.

Posti JP, Salo P, Ruohonen S, Valve L, Muszkat M, Sofowora GG, Kurnik D, Stein CM, Perola M, Scheinin M, Snapir A.

Pharmacogenet Genomics. 2013 Mar;23(3):127-134. doi: 10.1097/FPC.0b013e32835d247f.

9.

CYP2A6 genetic variation and dexmedetomidine disposition.

Kohli U, Pandharipande P, Muszkat M, Sofowora GG, Friedman EA, Scheinin M, Wood AJ, Ely EW, Tyndale RF, Choi L, Stein CM, Kurnik D.

Eur J Clin Pharmacol. 2012 Jun;68(6):937-42. doi: 10.1007/s00228-011-1208-z. Epub 2012 Jan 21.

10.

Catecholamine pathway gene variation is associated with norepinephrine and epinephrine concentrations at rest and after exercise.

Ghimire LV, Kohli U, Li C, Sofowora GG, Muszkat M, Friedman EA, Solus JF, Wood AJ, Stein CM, Kurnik D.

Pharmacogenet Genomics. 2012 Apr;22(4):254-60. doi: 10.1097/FPC.0b013e328350a274.

11.

Genetic variation in the presynaptic norepinephrine transporter is associated with blood pressure responses to exercise in healthy humans.

Kohli U, Hahn MK, English BA, Sofowora GG, Muszkat M, Li C, Blakely RD, Stein CM, Kurnik D.

Pharmacogenet Genomics. 2011 Apr;21(4):171-8. doi: 10.1097/FPC.0b013e328344f63e.

12.

Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine.

Kurnik D, Muszkat M, Li C, Sofowora GG, Friedman EA, Scheinin M, Wood AJ, Stein CM.

Circ Cardiovasc Genet. 2011 Apr;4(2):179-87. doi: 10.1161/CIRCGENETICS.110.957662. Epub 2011 Feb 15.

13.

Independent regulation of α1 and α2 adrenergic receptor-mediated vasoconstriction in vivo.

Muszkat M, Kurnik D, Sofowora GG, Wood AJ, Stein CM.

J Hypertens. 2011 Feb;29(2):251-6. doi: 10.1097/HJH.0b013e3283407ffd.

14.

Desensitization of vascular response in vivo: contribution of genetic variation in the [alpha]2B-adrenergic receptor subtype.

Muszkat M, Kurnik D, Sofowora GG, Solus J, Xie HG, Harris PA, Williams SM, Wood AJ, Stein CM.

J Hypertens. 2010 Feb;28(2):278-84. doi: 10.1097/HJH.0b013e328333d212.

15.

GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans.

Kurnik D, Cunningham AJ, Sofowora GG, Kohli U, Li C, Friedman EA, Muszkat M, Menon UB, Wood AJ, Stein CM.

Pharmacogenomics. 2009 Oct;10(10):1581-7. doi: 10.2217/pgs.09.92.

16.

Effects of variation in the human alpha2A- and alpha2C-adrenoceptor genes on cognitive tasks and pain perception.

Kohli U, Muszkat M, Sofowora GG, Harris PA, Friedman EA, Dupont WD, Scheinin M, Wood AJ, Stein CM, Kurnik D.

Eur J Pain. 2010 Feb;14(2):154-9. doi: 10.1016/j.ejpain.2009.04.003. Epub 2009 May 6.

17.

Tariquidar, a selective P-glycoprotein inhibitor, does not potentiate loperamide's opioid brain effects in humans despite full inhibition of lymphocyte P-glycoprotein.

Kurnik D, Sofowora GG, Donahue JP, Nair UB, Wilkinson GR, Wood AJ, Muszkat M.

Anesthesiology. 2008 Dec;109(6):1092-9. doi: 10.1097/ALN.0b013e31818d8f28.

PMID:
19034106
18.

Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade.

Kurnik D, Li C, Sofowora GG, Friedman EA, Muszkat M, Xie HG, Harris PA, Williams SM, Nair UB, Wood AJ, Stein CM.

Pharmacogenet Genomics. 2008 Oct;18(10):895-902. doi: 10.1097/FPC.0b013e328309733f.

19.

Genetic variants in the alpha2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses.

Kurnik D, Friedman EA, Muszkat M, Sofowora GG, Xie HG, Dupont WD, Wood AJ, Stein CM.

Pharmacogenet Genomics. 2008 Sep;18(9):743-50. doi: 10.1097/FPC.0b013e3282fee5a1.

20.

Ethnic and genetic determinants of cardiovascular response to the selective alpha 2-adrenoceptor agonist dexmedetomidine.

Kurnik D, Muszkat M, Sofowora GG, Friedman EA, Dupont WD, Scheinin M, Wood AJ, Stein CM.

Hypertension. 2008 Feb;51(2):406-11. Epub 2007 Dec 10.

PMID:
18071056
21.

Effect of the alpha2C-adrenoreceptor deletion322-325 variant on sympathetic activity and cardiovascular measures in healthy subjects.

Kurnik D, Muszkat M, Friedman EA, Sofowora GG, Diedrich A, Xie HG, Harris PA, Choi L, Wood AJ, Stein CM.

J Hypertens. 2007 Apr;25(4):763-71.

PMID:
17351367
22.

Variations in the alpha2A-adrenergic receptor gene and their functional effects.

Kurnik D, Muszkat M, Li C, Sofowora GG, Solus J, Xie HG, Harris PA, Jiang L, McMunn C, Ihrie P, Dawson EP, Williams SM, Wood AJ, Stein CM.

Clin Pharmacol Ther. 2006 Mar;79(3):173-85. Epub 2006 Feb 7.

PMID:
16513442
23.
24.

Variation in the alpha2B-adrenergic receptor gene (ADRA2B) and its relationship to vascular response in vivo.

Muszkat M, Kurnik D, Solus J, Sofowora GG, Xie HG, Jiang L, McMunn C, Ihrie P, Harris JR, Dawson EP, Williams SM, Wood AJ, Stein CM.

Pharmacogenet Genomics. 2005 Jun;15(6):407-14.

PMID:
15900214
25.

Alpha2B adrenergic receptor 301-303 deletion polymorphism and vascular alpha2 adrenergic receptor response.

Muszkat M, Sofowora GG, Xie HG, Wood AJ, Stein CM.

Pharmacogenet Genomics. 2005 Jan;15(1):23-8.

PMID:
15864122
26.

Beta2-adrenoceptor Thr164Ile polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo.

Dishy V, Landau R, Sofowora GG, Xie HG, Smiley RM, Kim RB, Byrne DW, Wood AJ, Stein CM.

Pharmacogenetics. 2004 Aug;14(8):517-22.

PMID:
15284533
27.

Alpha 1A-adrenergic receptor polymorphism and vascular response.

Sofowora GG, Dishy V, Landau R, Xie HG, Prasad HC, Byrne DW, Smiley RM, Kim RB, Wood AJ, Stein CM.

Clin Pharmacol Ther. 2004 Jun;75(6):539-45.

PMID:
15179408
28.

Sildenafil does not improve nitric oxide-mediated endothelium-dependent vascular responses in smokers.

Dishy V, Harris PA, Pierce R, Prasad HC, Sofowora G, Bonar HL, Wood AJ, Stein CM.

Br J Clin Pharmacol. 2004 Feb;57(2):209-12.

29.

Alpha2-adrenergic receptor-induced vascular constriction in blacks and whites.

Muszkat M, Sofowora GG, Wood AJ, Stein CM.

Hypertension. 2004 Jan;43(1):31-5. Epub 2003 Dec 1.

PMID:
14656950
32.

A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade.

Sofowora GG, Dishy V, Muszkat M, Xie HG, Kim RB, Harris PA, Prasad HC, Byrne DW, Nair UB, Wood AJ, Stein CM.

Clin Pharmacol Ther. 2003 Apr;73(4):366-71.

PMID:
12709726
33.

Nitric oxide production decreases after salt loading but is not related to blood pressure changes or nitric oxide-mediated vascular responses.

Dishy V, Sofowora GG, Imamura H, Nishimi Y, Xie HG, Wood AJ, Stein CM.

J Hypertens. 2003 Jan;21(1):153-7.

PMID:
12544447
34.

In-vivo effects of Glu298Asp endothelial nitric oxide synthase polymorphism.

Sofowora G, Dishy V, Xie HG, Imamura H, Nishimi Y, Morales CR, Morrow JD, Kim RB, Stein CM, Wood AJ.

Pharmacogenetics. 2001 Dec;11(9):809-14.

PMID:
11740345
35.

The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization.

Dishy V, Sofowora GG, Xie HG, Kim RB, Byrne DW, Stein CM, Wood AJ.

N Engl J Med. 2001 Oct 4;345(14):1030-5.

36.

The effect of sildenafil on nitric oxide-mediated vasodilation in healthy men.

Dishy V, Sofowora G, Harris PA, Kandcer M, Zhan F, Wood AJ, Stein CM.

Clin Pharmacol Ther. 2001 Sep;70(3):270-9.

PMID:
11557915
37.

In vivo inhibition of human CYP1A2 activity by oltipraz.

Sofowora GG, Choo EF, Mayo G, Shyr Y, Wilkinson GR.

Cancer Chemother Pharmacol. 2001 Jun;47(6):505-10.

PMID:
11459203
38.

Arg389Gly beta 1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo.

Xie HG, Dishy V, Sofowora G, Kim RB, Landau R, Smiley RM, Zhou HH, Wood AJ, Harris P, Stein CM.

Pharmacogenetics. 2001 Apr;11(3):191-7.

PMID:
11337934
40.

Human beta2-adrenergic receptor polymorphisms: no association with essential hypertension in black or white Americans.

Xie HG, Stein CM, Kim RB, Gainer JV, Sofowora G, Dishy V, Brown NJ, Goree RE, Haines JL, Wood AJ.

Clin Pharmacol Ther. 2000 Jun;67(6):670-5.

PMID:
10872649
41.
42.
44.
45.

Clinical implications of alpha 1 adrenergic blockade and angiotensin converting enzyme inhibition 'cross talk' in heart failure in Nigerians.

Ajayi AA, Sofowora G, Balogun MO.

Afr J Med Med Sci. 1996 Mar;25(1):95. No abstract available.

PMID:
9110062
46.

A double-blind, placebo-controlled study of the efficacy of thiamine hydrochloride in a seasonal ataxia in Nigerians.

Adamolekun B, Adamolekun WE, Sonibare AD, Sofowora G.

Neurology. 1994 Mar;44(3 Pt 1):549-51.

PMID:
8145931

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