Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 194

1.

Reactivity of atropaldehyde, a felbamate metabolite in human liver tissue in vitro.

Kapetanovic IM, Torchin CD, Strong JM, Yonekawa WD, Lu C, Li AP, Dieckhaus CM, Santos WL, Macdonald TL, Sofia RD, Kupferberg HJ.

Chem Biol Interact. 2002 Nov 10;142(1-2):119-34.

PMID:
12399159
2.
3.

Interaction between human serum albumin and the felbamate metabolites 4-Hydroxy-5-phenyl-[1,3]oxazinan-2-one and 2-phenylpropenal.

Roller SG, Dieckhaus CM, Santos WL, Sofia RD, Macdonald TL.

Chem Res Toxicol. 2002 Jun;15(6):815-24.

PMID:
12067249
4.

Linkage disequilibrium of HLA-A11 and A1 with one of the polymorphisms of the gamma-aminobutyric acid receptor type B.

Anaya M, Romero T, Sofia RD, Yunis EJ.

Tissue Antigens. 2001 Nov;58(5):324-8.

PMID:
11844143
5.

Felbamate-induced apoptosis of hematopoietic cells is mediated by redox-sensitive and redox-independent pathways.

Husain Z, Pinto C, Sofia RD, Yunis EJ.

Epilepsy Res. 2002 Jan;48(1-2):57-69.

PMID:
11823110
6.
7.

Role of glutathione S-transferases A1-1, M1-1, and P1-1 in the detoxification of 2-phenylpropenal, a reactive felbamate metabolite.

Dieckhaus CM, Roller SG, Santos WL, Sofia RD, Macdonald TL.

Chem Res Toxicol. 2001 May;14(5):511-6.

PMID:
11368548
8.

A self-complementary, self-assembling microsphere system: application for intravenous delivery of the antiepileptic and neuroprotectant compound felbamate.

Lian H, Steiner SS, Sofia RD, Woodhead JH, Wolf HH, White HS, Shen GS, Rhodes CA, McCabe RT.

J Pharm Sci. 2000 Jul;89(7):867-75.

PMID:
10861587
9.

A mechanistic approach to understanding species differences in felbamate bioactivation: relevance to drug-induced idiosyncratic reactions.

Dieckhaus CM, Miller TA, Sofia RD, Macdonald TL.

Drug Metab Dispos. 2000 Jul;28(7):814-22.

PMID:
10859156
10.

Activities of taurolidine in vitro and in experimental enterococcal endocarditis.

Torres-Viera C, Thauvin-Eliopoulos C, Souli M, DeGirolami P, Farris MG, Wennersten CB, Sofia RD, Eliopoulos GM.

Antimicrob Agents Chemother. 2000 Jun;44(6):1720-4.

11.

The synthesis, in vitro reactivity, and evidence for formation in humans of 5-phenyl-1,3-oxazinane-2,4-dione, a metabolite of felbamate.

Thompson CD, Miller TA, Barthen MT, Dieckhaus CM, Sofia RD, Macdonald TL.

Drug Metab Dispos. 2000 Apr;28(4):434-9.

PMID:
10725312
12.

Felbamate in experimental model of status epilepticus.

Mazarati AM, Baldwin RA, Sofia RD, Wasterain CG.

Epilepsia. 2000 Feb;41(2):123-7.

13.

Quantification in patient urine samples of felbamate and three metabolites: acid carbamate and two mercapturic acids.

Thompson CD, Barthen MT, Hopper DW, Miller TA, Quigg M, Hudspeth C, Montouris G, Marsh L, Perhach JL, Sofia RD, Macdonald TL.

Epilepsia. 1999 Jun;40(6):769-76.

14.

Acute, subchronic, and chronic toxicity studies with felbamate, 2-phenyl-1,3-propanediol dicarbamate.

McGee JH, Erikson DJ, Galbreath C, Willigan DA, Sofia RD.

Toxicol Sci. 1998 Oct;45(2):225-32.

PMID:
9848129
15.

Oncogenic studies with felbamate (2-phenyl-1,3-propanediol dicarbamate).

McGee JH, Butler WH, Erikson DJ, Sofia RD.

Toxicol Sci. 1998 Oct;45(2):146-51.

PMID:
9848121
16.

Potentially reactive cyclic carbamate metabolite of the antiepileptic drug felbamate produced by human liver tissue in vitro.

Kapetanovic IM, Torchin CD, Thompson CD, Miller TA, McNeilly PJ, Macdonald TL, Kupferberg HJ, Perhach JL, Sofia RD, Strong JM.

Drug Metab Dispos. 1998 Nov;26(11):1089-95.

PMID:
9806951
17.

Felbamate increases [3H]glycine binding in rat brain and sections of human postmortem brain.

McCabe RT, Sofia RD, Layer RT, Leiner KA, Faull RL, Narang N, Wamsley JK.

J Pharmacol Exp Ther. 1998 Aug;286(2):991-9.

PMID:
9694960
18.

In vivo mutagenicity studies with iodinated glycerol azeo.

McGee JH, San Sebastian JR, Sofia RD.

Mutat Res. 1997 Dec 5;395(1):29-36.

PMID:
9465911
19.

Experimental studies on acute and chronic action of azelastine on nasal mucosa in guinea pigs, rats and dogs.

Achterrath-Tuckermann U, Berthold K, Roux J, Procter BG, McDonald P, Szelenyi I, Sofia RD, Herbst M.

Arzneimittelforschung. 1997 Nov;47(11):1230-2.

PMID:
9428980
20.

Felbamate protects CA1 neurons from apoptosis in a gerbil model of global ischemia.

Wasterlain CG, Adams LM, Wichmann JK, Sofia RD.

Stroke. 1996 Jul;27(7):1236-40.

PMID:
8685935
21.

Distribution of felbamate in brain.

Cornford EM, Truong HV, Sofia RD, Kucharczyk N.

Epilepsia. 1996 Jan;37(1):15-8.

PMID:
8603617
22.

Analysis of anticonvulsant and neurotoxic responses to combination therapy with carbamazepine, felbamate and phenytoin by response-surface modeling.

Gennings C, Sofia RD, Carchman RA, Carter WH Jr, Swinyard EA.

Arzneimittelforschung. 1995 Jul;45(7):739-48.

PMID:
8573214
23.

Synergistic protective effects with azelastine and salbutamol in a guinea pig asthma model.

Chand N, Achterrath-Tuckermann U, Szelenyi I, Sofia RD.

Res Commun Mol Pathol Pharmacol. 1995 Feb;87(2):125-32.

PMID:
7749650
24.
25.

Felbamate modulates the strychnine-insensitive glycine receptor.

White HS, Harmsworth WL, Sofia RD, Wolf HH.

Epilepsy Res. 1995 Jan;20(1):41-8.

PMID:
7713059
26.

Interaction of felbamate with [3H]DCKA-labeled strychnine-insensitive glycine receptors in human postmortem brain.

Wamsley JK, Sofia RD, Faull RL, Narang N, Ary T, McCabe RT.

Exp Neurol. 1994 Oct;129(2):244-50.

PMID:
7957739
27.
28.

Effect of PAF-antagonists on aeroallergen-induced bronchial eosinophilia in guinea pigs: a therapeutic approach.

Chand N, Harrison JE, Sofia RD.

Res Commun Mol Pathol Pharmacol. 1994 Oct;86(1):75-82.

PMID:
7850258
29.

Azelastine inhibits acute allergic dyspnea in a conscious guinea pig asthma model.

Chand N, Diamantis W, Nolan K, Pillar J, Sofia RD.

Res Commun Mol Pathol Pharmacol. 1994 Aug;85(2):209-16.

PMID:
7994565
30.

Determination of valproate in the presence of felbamate in human plasma by narrow bore capillary gas chromatography.

Romanyshyn LA, Wagner MC, Wichmann JK, Kucharczyk N, Sofia RD.

Epilepsia. 1994 Mar-Apr;35(2):406-10.

PMID:
8156966
32.

Simultaneous determination of felbamate and three metabolites in human plasma by high-performance liquid chromatography.

Romanyshyn LA, Wichmann JK, Kucharczyk N, Sofia RD.

Ther Drug Monit. 1994 Feb;16(1):83-9.

PMID:
8160261
33.

Comparative effects of felbamate and other compounds on N-methyl-D-aspartic acid-induced convulsions and lethality in mice.

Sofia RD, Gordon R, Gels M, Diamantis W.

Pharmacol Res. 1994 Feb-Mar;29(2):139-44.

PMID:
8058587
34.

Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate.

Adusumalli VE, Wichmann JK, Kucharczyk N, Kamin M, Sofia RD, French J, Sperling M, Bourgeois B, Devinsky O, Dreifuss FE, et al.

Drug Metab Dispos. 1994 Jan-Feb;22(1):168-70. No abstract available.

PMID:
8149879
35.

Felbamate: interaction with glycine receptors in human cerebral cortex.

Wamsley JK, Sofia RD, Faull RL, Narang N, Ary T, Gan XD, McCabe RT.

Proc West Pharmacol Soc. 1994;37:81-3. No abstract available.

PMID:
7984680
36.

Use of [3H]5,7 dichlorokynurenic acid to identify strychnine-insensitive glycine receptors in human postmortem brain.

Wamsley JK, Sofia RD, Faull RL, Ary T, Narang N, McCabe RT.

Brain Res Bull. 1994;35(3):205-9.

PMID:
7812798
37.

Simultaneous determination of felbamate and three metabolites in rat and dog plasmas by high-performance liquid chromatography.

Romanyshyn LA, Wichmann JK, Kucharczyk N, Sofia RD.

J Chromatogr. 1993 Dec 22;622(2):229-34.

PMID:
8150870
38.

Simultaneous determination of felbamate and four metabolites in rat cerebrospinal fluid by high-performance liquid chromatography.

Romanyshyn LA, Wichmann JK, Kucharczyk N, Sofia RD.

J Chromatogr. 1993 Dec 22;622(2):223-8.

PMID:
8150869
39.

Posthypoxic treatment with felbamate is neuroprotective in a rat model of hypoxia-ischemia.

Wasterlain CG, Adams LM, Schwartz PH, Hattori H, Sofia RD, Wichmann JK.

Neurology. 1993 Nov;43(11):2303-10.

PMID:
8232947
40.

Allergic bronchial eosinophilia: a therapeutic approach for the selection of potential bronchial anti-inflammatory drugs.

Chand N, Harrison JE, Rooney SM, Nolan KW, De Vine CL, Jakubicki RG, Pillar J, Diamantis W, Sofia RD.

Allergy. 1993 Nov;48(8):624-6.

PMID:
8116861
41.

Distribution of the anticonvulsant felbamate to cerebrospinal fluid and brain tissue of adult and neonatal rats.

Adusumalli VE, Wichmann JK, Kucharczyk N, Sofia RD.

Drug Metab Dispos. 1993 Nov-Dec;21(6):1079-85.

PMID:
7905387
42.

Critique of the toxicology and carcinogenesis studies of iodinated glycerol in F344/N rats and B6C3F1 mice.

McGee JH, Butler WH, Willigan DA, Brown WR, Sofia RD.

Regul Toxicol Pharmacol. 1993 Oct;18(2):169-80.

PMID:
8278639
43.

Isolation and identification of 3-carbamoyloxy-2-phenylpropionic acid as a major human urinary metabolite of felbamate.

Adusumalli VE, Choi YM, Romanyshyn LA, Sparadoski RE Jr, Wichmann JK, Wong KK, Kucharczyk N, Sofia RD.

Drug Metab Dispos. 1993 Jul-Aug;21(4):710-6.

PMID:
8104132
44.

Determination of the anticonvulsant felbamate and its three metabolites in brain and heart tissue of rats.

Jacala A, Adusumalli VE, Kucharczyk N, Sofia RD.

J Chromatogr. 1993 May 5;614(2):285-92.

PMID:
8314941
45.

Aeroallergen-induced dyspnea in freely moving guinea pigs: quantitative measurement by bias flow ventilated whole body plethysmography.

Chand N, Nolan K, Pillar J, Lomask M, Diamantis W, Sofia RD.

Allergy. 1993 May;48(4):230-5.

PMID:
8328657
46.

Pharmacokinetics of the new antiasthma and antiallergy drug, azelastine, in pediatric and adult beagle dogs.

Adusumalli VE, Wichmann JK, Wong KK, Kucharczyk N, Sofia RD.

Biopharm Drug Dispos. 1993 Apr;14(3):233-44.

PMID:
8098227
47.

Effects of felbamate and other anticonvulsant drugs in two models of status epilepticus in the rat.

Sofia RD, Gordon R, Gels M, Diamantis W.

Res Commun Chem Pathol Pharmacol. 1993 Mar;79(3):335-41.

PMID:
8480078
48.

Interaction of felbamate with several other antiepileptic drugs against seizures induced by maximal electroshock in mice.

Gordon R, Gels M, Wichmann J, Diamantis W, Sofia RD.

Epilepsia. 1993 Mar-Apr;34(2):367-71.

PMID:
8453946
49.

Evidence for anticonvulsant and neuroprotectant action of felbamate mediated by strychnine-insensitive glycine receptors.

McCabe RT, Wasterlain CG, Kucharczyk N, Sofia RD, Vogel JR.

J Pharmacol Exp Ther. 1993 Mar;264(3):1248-52.

PMID:
8383742
50.

Mucolytic activity of azelastine in mice and rats.

Chand N, Harrison JE, Rooney S, Diamantis W, Sofia RD.

Agents Actions. 1993 Mar;38(3-4):165-70.

PMID:
8105642

Supplemental Content

Loading ...
Support Center