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Items: 1 to 50 of 145

1.

Highly sweet compounds of plant origin: From ethnobotanical observations to wide utilization.

Soejarto DD, Addo EM, Kinghorn AD.

J Ethnopharmacol. 2019 Oct 28;243:112056. doi: 10.1016/j.jep.2019.112056. Epub 2019 Jul 3. Review.

PMID:
31279071
2.

Caspase-Dependent Apoptosis in Prostate Cancer Cells and Zebrafish by Corchorusoside C from Streptocaulon juventas.

Anaya-Eugenio GD, Addo EM, Ezzone N, Henkin JM, Ninh TN, Ren Y, Soejarto DD, Kinghorn AD, Carcache de Blanco EJ.

J Nat Prod. 2019 Jun 28;82(6):1645-1655. doi: 10.1021/acs.jnatprod.9b00140. Epub 2019 May 23.

PMID:
31120251
3.

Potential Anticancer Agents Characterized from Selected Tropical Plants.

Ren Y, de Blanco EJC, Fuchs JR, Soejarto DD, Burdette JE, Swanson SM, Kinghorn AD.

J Nat Prod. 2019 Mar 22;82(3):657-679. doi: 10.1021/acs.jnatprod.9b00018. Epub 2019 Mar 4.

PMID:
30830783
4.

Bioactivity-Guided Isolation of Totarane-Derived Diterpenes from Podocarpus neriifolius and Structure Revision of 3-Deoxy-2α-hydroxynagilactone E.

Benatrehina PA, Chen WL, Czarnecki AA, Kurina S, Chai HB, Lantvit DD, Ninh TN, Zhang X, Soejarto DD, Burdette JE, Kinghorn AD, Rakotondraibe LH.

Nat Prod Bioprospect. 2019 Apr;9(2):157-163. doi: 10.1007/s13659-019-0198-x. Epub 2019 Feb 19.

5.

Non-Destructive Chemical Analysis of a Garcinia mangostana L. (Mangosteen) Herbarium Voucher Specimen.

Kao D, Henkin JM, Soejarto DD, Kinghorn AD, Oberlies NH.

Phytochem Lett. 2018 Dec;28:124-129. doi: 10.1016/j.phytol.2018.10.001. Epub 2018 Oct 12.

PMID:
30613309
6.

The Search for Anticancer Agents from Tropical Plants.

Henkin JM, Ren Y, Soejarto DD, Kinghorn AD.

Prog Chem Org Nat Prod. 2018;107:1-94. doi: 10.1007/978-3-319-93506-5_1. Review.

PMID:
30178270
7.

Cytotoxic and NF-κB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives.

Ren Y, Anaya-Eugenio GD, Czarnecki AA, Ninh TN, Yuan C, Chai HB, Soejarto DD, Burdette JE, de Blanco EJC, Kinghorn AD.

Bioorg Med Chem. 2018 Aug 15;26(15):4452-4460. doi: 10.1016/j.bmc.2018.07.025. Epub 2018 Jul 17.

8.

Revisiting the linkage between ethnomedical use and development of new medicines: A novel plant collection strategy towards the discovery of anticancer agents.

Henkin JM, Sydara K, Xayvue M, Souliya O, Kinghorn AD, Burdette JE, Chen WL, Elkington BG, Soejarto DD.

J Med Plant Res. 2017 Oct;11(40):621-634. Epub 2017 Oct 25.

9.

Correction to Potent Inhibitor of Drug-Resistant HIV-1 Strains Identified from the Medicinal Plant Justicia gendarussa.

Zhang HJ, Rumschlag-Booms E, Guan YF, Wang DY, Liu KL, Li WF, Nguyen VH, Cuong NM, Soejarto DD, Fong HHS, Rong L.

J Nat Prod. 2017 Aug 25;80(8):2390. doi: 10.1021/acs.jnatprod.7b00562. Epub 2017 Jul 20. No abstract available.

PMID:
28727428
10.

Potent Inhibitor of Drug-Resistant HIV-1 Strains Identified from the Medicinal Plant Justicia gendarussa.

Zhang HJ, Rumschlag-Booms E, Guan YF, Wang DY, Liu KL, Li WF, Nguyen VH, Cuong NM, Soejarto DD, Fong HHS, Rong L.

J Nat Prod. 2017 Jun 23;80(6):1798-1807. doi: 10.1021/acs.jnatprod.7b00004. Epub 2017 Jun 14. Erratum in: J Nat Prod. 2017 Aug 25;80(8):2390.

PMID:
28613071
11.

Anti-HIV diphyllin glycosides from Justicia gendarussa.

Zhang HJ, Rumschlag-Booms E, Guan YF, Liu KL, Wang DY, Li WF, Nguyen VH, Cuong NM, Soejarto DD, Fong HHS, Rong L.

Phytochemistry. 2017 Apr;136:94-100. doi: 10.1016/j.phytochem.2017.01.005. Epub 2017 Jan 19.

PMID:
28110956
12.

Cardiac Glycoside Constituents of Streblus asper with Potential Antineoplastic Activity.

Ren Y, Chen WL, Lantvit DD, Sass EJ, Shriwas P, Ninh TN, Chai HB, Zhang X, Soejarto DD, Chen X, Lucas DM, Swanson SM, Burdette JE, Kinghorn AD.

J Nat Prod. 2017 Mar 24;80(3):648-658. doi: 10.1021/acs.jnatprod.6b00924. Epub 2016 Dec 16.

13.

Discovery of Bioactive Compounds by the UIC-ICBG Drug Discovery Program in the 18 Years Since 1998.

Zhang HJ, Li WF, Fong HH, Soejarto DD.

Molecules. 2016 Oct 31;21(11). pii: E1448. Review.

14.

Discovery of Anticancer Agents of Diverse Natural Origin.

Kinghorn AD, DE Blanco EJ, Lucas DM, Rakotondraibe HL, Orjala J, Soejarto DD, Oberlies NH, Pearce CJ, Wani MC, Stockwell BR, Burdette JE, Swanson SM, Fuchs JR, Phelps MA, Xu L, Zhang X, Shen YY.

Anticancer Res. 2016 Nov;36(11):5623-5637. Review.

15.

Isolation of Bioactive Rotenoids and Isoflavonoids from the Fruits of Millettia caerulea.

Ren Y, Benatrehina PA, Muñoz Acuña U, Yuan C, Chai HB, Ninh TN, Carcache de Blanco EJ, Soejarto DD, Kinghorn AD.

Planta Med. 2016 Jul;82(11-12):1096-104. doi: 10.1055/s-0042-108059. Epub 2016 Jun 9.

16.

Litsea Species as Potential Antiviral Plant Sources.

Guan Y, Wang D, Tan GT, Van Hung N, Cuong NM, Pezzuto JM, Fong HH, Soejarto DD, Zhang H.

Am J Chin Med. 2016;44(2):275-90. doi: 10.1142/S0192415X16500166. Review.

PMID:
27080941
17.

Bioassay-Guided Isolation and Structural Modification of the Anti-TB Resorcinols from Ardisia gigantifolia.

Guan YF, Song X, Qiu MH, Luo SH, Wang BJ, Van Hung N, Cuong NM, Soejarto DD, Fong HH, Franzblau SG, Li SH, He ZD, Zhang HJ.

Chem Biol Drug Des. 2016 Aug;88(2):293-301. doi: 10.1111/cbdd.12756. Epub 2016 Apr 26.

PMID:
26992112
18.

New Bioactive Lupane Triterpene Coumaroyl Esters Isolated from Buxus cochinchinensis.

Pan L, Muñoz Acuña U, Chai H, Park HY, Ninh TN, Thanh BV, Merino EF, Cassera MB, Rakotondraibe LH, Carcache de Blanco EJ, Soejarto DD, Kinghorn AD.

Planta Med. 2015 Aug;81(12-13):1133-40. doi: 10.1055/s-0035-1546118. Epub 2015 Jul 1.

19.

Species-specific Standardisation of Licorice by Metabolomic Profiling of Flavanones and Chalcones.

Simmler C, Jones T, Anderson JR, Nikolić DC, van Breemen RB, Soejarto DD, Chen SN, Pauli GF.

Phytochem Anal. 2014 Jul-Aug;25(4):378-88. doi: 10.1002/pca.2472. Epub 2013 Nov 13.

20.

Cytotoxic and natural killer cell stimulatory constituents of Phyllanthus songboiensis.

Ren Y, Yuan C, Deng Y, Kanagasabai R, Ninh TN, Tu VT, Chai HB, Soejarto DD, Fuchs JR, Yalowich JC, Yu J, Kinghorn AD.

Phytochemistry. 2015 Mar;111:132-40. doi: 10.1016/j.phytochem.2014.12.014. Epub 2015 Jan 14.

21.

Bioactive indole alkaloids isolated from Alstonia angustifolia.

Pan L, Terrazas C, Muñoz Acuña U, Ninh TN, Chai H, Carcache de Blanco EJ, Soejarto DD, Satoskar AR, Kinghorn AD.

Phytochem Lett. 2014 Dec;10:54-59.

22.

Investigation of Vietnamese plants for potential anticancer agents.

Pérez LB, Still PC, Naman CB, Ren Y, Pan L, Chai HB, Carcache de Blanco EJ, Ninh TN, Van Thanh B, Swanson SM, Soejarto DD, Kinghorn AD.

Phytochem Rev. 2014 Dec;13(4):727-739.

23.

Assessment of the importance of medicinal plants among communities around Khiat Ngong of southern Laos.

Elkington BG, Phiapalath P, Sydara K, Somsamouth V, Goodsmith NI, Soejarto DD.

J Environ Biol. 2014 Jul;35(4):607-15.

PMID:
25004742
24.

Potent cytotoxic arylnaphthalene lignan lactones from Phyllanthus poilanei.

Ren Y, Lantvit DD, Deng Y, Kanagasabai R, Gallucci JC, Ninh TN, Chai HB, Soejarto DD, Fuchs JR, Yalowich JC, Yu J, Swanson SM, Kinghorn AD.

J Nat Prod. 2014 Jun 27;77(6):1494-504. doi: 10.1021/np5002785. Epub 2014 Jun 12.

25.

Caeruleanone A, a rotenoid with a new arrangement of the D-ring from the fruits of Millettia caerulea.

Bueno Pérez L, Pan L, Muñoz Acuña U, Li J, Chai HB, Gallucci JC, Ninh TN, Carcache de Blanco EJ, Soejarto DD, Kinghorn AD.

Org Lett. 2014 Mar 7;16(5):1462-5. doi: 10.1021/ol500266z. Epub 2014 Feb 19.

26.

Bioactive compounds from Vitex leptobotrys.

Pan W, Liu K, Guan Y, Tan GT, Hung NV, Cuong NM, Soejarto DD, Pezzuto JM, Fong HH, Zhang H.

J Nat Prod. 2014 Mar 28;77(3):663-7. doi: 10.1021/np400779v. Epub 2014 Jan 9.

27.

New finding of an anti-TB compound in the genus Marsypopetalum (Annonaceae) from a traditional herbal remedy of Laos.

Elkington BG, Sydara K, Newsome A, Hwang CH, Lankin DC, Simmler C, Napolitano JG, Ree R, Graham JG, Gyllenhaal C, Bouamanivong S, Souliya O, Pauli GF, Franzblau SG, Soejarto DD.

J Ethnopharmacol. 2014 Feb 3;151(2):903-11. doi: 10.1016/j.jep.2013.11.057. Epub 2013 Dec 11.

28.

A cytotoxic dimeric furanoheliangolide from Piptocoma rufescens.

Ren Y, Jiménez F, García R, Mejía M, Chai H, Farnsworth NR, Soejarto DD, Kinghorn AD.

Tetrahedron Lett. 2013 Oct 2;54(40):5457-5460.

29.

Sphenostylisins A-K: bioactive modified isoflavonoid constituents of the root bark of Sphenostylis marginata ssp. erecta.

Li J, Pan L, Deng Y, Muñoz-Acuña U, Yuan C, Lai H, Chai H, Chagwedera TE, Farnsworth NR, Carcache de Blanco EJ, Li C, Soejarto DD, Kinghorn AD.

J Org Chem. 2013 Oct 18;78(20):10166-77. doi: 10.1021/jo401573h. Epub 2013 Oct 3.

30.

Lipidated steroid saponins from Dioscorea villosa (wild yam).

Dong SH, Cai G, Napolitano JG, Nikolić D, Lankin DC, McAlpine JB, van Breemen RB, Soejarto DD, Pauli GF, Chen SN.

Fitoterapia. 2013 Dec;91:113-124. doi: 10.1016/j.fitote.2013.07.018. Epub 2013 Aug 19.

31.

Bioactive constituents of Indigofera spicata.

Bueno Pérez L, Li J, Lantvit DD, Pan L, Ninh TN, Chai HB, Soejarto DD, Swanson SM, Lucas DM, Kinghorn AD.

J Nat Prod. 2013 Aug 23;76(8):1498-504. doi: 10.1021/np400567c. Epub 2013 Jul 30.

32.

Folk Epidemiology Recorded in Palm Leaf Manuscripts of Laos.

Elkington BG, Sydara K, Hartmann JF, Southavong B, Soejarto DD.

J Lao Stud. 2013 Oct 1;3(1):1-14.

33.

Accurate mass-time tag library for LC/MS-based metabolite profiling of medicinal plants.

Cuthbertson DJ, Johnson SR, Piljac-Žegarac J, Kappel J, Schäfer S, Wüst M, Ketchum RE, Croteau RB, Marques JV, Davin LB, Lewis NG, Rolf M, Kutchan TM, Soejarto DD, Lange BM.

Phytochemistry. 2013 Jul;91:187-97. doi: 10.1016/j.phytochem.2013.02.018. Epub 2013 Apr 16.

34.

Dynamic residual complexity of the isoliquiritigenin-liquiritigenin interconversion during bioassay.

Simmler C, Hajirahimkhan A, Lankin DC, Bolton JL, Jones T, Soejarto DD, Chen SN, Pauli GF.

J Agric Food Chem. 2013 Mar 6;61(9):2146-57. doi: 10.1021/jf304445p. Epub 2013 Feb 22.

35.

Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities.

Still PC, Yi B, González-Cestari TF, Pan L, Pavlovicz RE, Chai HB, Ninh TN, Li C, Soejarto DD, McKay DB, Kinghorn AD.

J Nat Prod. 2013 Feb 22;76(2):243-9. doi: 10.1021/np3007414. Epub 2013 Jan 17.

36.

Bioactive flavaglines and other constituents isolated from Aglaia perviridis.

Pan L, Acuña UM, Li J, Jena N, Ninh TN, Pannell CM, Chai H, Fuchs JR, Carcache de Blanco EJ, Soejarto DD, Kinghorn AD.

J Nat Prod. 2013 Mar 22;76(3):394-404. doi: 10.1021/np3007588. Epub 2013 Jan 9.

37.

Diarylheptanoids from Dioscorea villosa (Wild Yam).

Dong SH, Nikolić D, Simmler C, Qiu F, van Breemen RB, Soejarto DD, Pauli GF, Chen SN.

J Nat Prod. 2012 Dec 28;75(12):2168-77. doi: 10.1021/np300603z. Epub 2012 Dec 17. Erratum in: J Nat Prod. 2013 Oct 25;76(10):2005-7.

38.

Use of the hollow fiber assay for the discovery of novel anticancer agents from fungi.

Pearce CJ, Lantvit DD, Shen Q, Jarjoura D, Zhang X, Oberlies NH, Kroll DJ, Wani MC, Orjala J, Soejarto DD, Farnsworth NR, de Blanco EJ, Fuchs JR, Kinghorn AD, Swanson SM.

Methods Mol Biol. 2012;944:267-77. doi: 10.1007/978-1-62703-122-6_20.

PMID:
23065624
39.

Cytotoxic and NF-κB inhibitory sesquiterpene lactones from Piptocoma rufescens.

Ren Y, Acuña UM, Jiménez F, García R, Mejía M, Chai H, Gallucci JC, Farnsworth NR, Soejarto DD, Carcache de Blanco EJ, Kinghorn AD.

Tetrahedron. 2012 Mar 25;68(12):2671-2678. Epub 2012 Jan 26.

40.

Isolation, structure elucidation, and biological evaluation of 16,23-epoxycucurbitacin constituents from Eleaocarpus chinensis.

Pan L, Yong Y, Deng Y, Lantvit DD, Ninh TN, Chai H, Carcache de Blanco EJ, Soejarto DD, Swanson SM, Kinghorn AD.

J Nat Prod. 2012 Mar 23;75(3):444-52. doi: 10.1021/np200879p. Epub 2012 Jan 12.

41.

Ethnobotanical approach versus random approach in the search for new bioactive compounds: support of a hypothesis.

Gyllenhaal C, Kadushin MR, Southavong B, Sydara K, Bouamanivong S, Xaiveu M, Xuan LT, Hiep NT, Hung NV, Loc PK, Dac LX, Bich TQ, Cuong NM, Ly HM, Zhang HJ, Franzblau SG, Xie H, Riley MC, Elkington BG, Nguyen HT, Waller DP, Ma CY, Tamez P, Tan GT, Pezzuto JM, Soejarto DD.

Pharm Biol. 2012 Jan;50(1):30-41. doi: 10.3109/13880209.2011.634424.

42.

Development of an Antiviral Screening Protocol: One-Stone-Two-Birds.

Rumschlag-Booms E, Zhang H, Soejarto DD, Fong HH, Rong L.

J Antivir Antiretrovir. 2011 Jan 7;3:8-10.

43.

An ethnobotanical survey of medicinal plants of Laos toward the discovery of bioactive compounds as potential candidates for pharmaceutical development.

Soejarto DD, Gyllenhaal C, Kadushin MR, Southavong B, Sydara K, Bouamanivong S, Xaiveu M, Zhang HJ, Franzblau SG, Tan GT, Pezzuto JM, Riley MC, Elkington BG, Waller DP.

Pharm Biol. 2012 Jan;50(1):42-60. doi: 10.3109/13880209.2011.619700. Epub 2011 Dec 2. Erratum in: Pharm Biol. 2012 Jun;50(6):799.

44.

Bioassay-guided isolation of constituents of Piper sarmentosum using a mitochondrial transmembrane potential assay.

Pan L, Matthew S, Lantvit DD, Zhang X, Ninh TN, Chai H, Carcache de Blanco EJ, Soejarto DD, Swanson SM, Kinghorn AD.

J Nat Prod. 2011 Oct 28;74(10):2193-9. doi: 10.1021/np200557e. Epub 2011 Oct 5.

45.

Phytochemical and Bioactivity Studies on Constituents of the Leaves of Vitex Quinata.

Deng Y, Chin YW, Chai HB, de Blanco EC, Kardono LB, Riswan S, Soejarto DD, Farnsworth NR, Kinghorn AD.

Phytochem Lett. 2011 Sep 1;4(3):213-217.

46.

Antituberculosis cycloartane triterpenoids from Radermachera boniana.

Truong NB, Pham CV, Doan HT, Nguyen HV, Nguyen CM, Nguyen HT, Zhang HJ, Fong HH, Franzblau SG, Soejarto DD, Chau MV.

J Nat Prod. 2011 May 27;74(5):1318-22. doi: 10.1021/np200022b. Epub 2011 Apr 6.

47.

Cytotoxic and NF-κB inhibitory constituents of the stems of Cratoxylum cochinchinense and their semisynthetic analogues.

Ren Y, Matthew S, Lantvit DD, Ninh TN, Chai H, Fuchs JR, Soejarto DD, de Blanco EJ, Swanson SM, Kinghorn AD.

J Nat Prod. 2011 May 27;74(5):1117-25. doi: 10.1021/np200051j. Epub 2011 Mar 23.

48.

Isolation and characterization of minor analogues of silvestrol and other constituents from a large-scale re-collection of Aglaia foveolata.

Pan L, Kardono LB, Riswan S, Chai H, Carcache de Blanco EJ, Pannell CM, Soejarto DD, McCloud TG, Newman DJ, Kinghorn AD.

J Nat Prod. 2010 Nov 29;73(11):1873-8. doi: 10.1021/np100503q. Epub 2010 Oct 12.

49.

Cytotoxic and NF-kappaB inhibitory constituents of Artocarpus rigida.

Ren Y, Kardono LB, Riswan S, Chai H, Farnsworth NR, Soejarto DD, Carcache de Blanco EJ, Kinghorn AD.

J Nat Prod. 2010 May 28;73(5):949-55. doi: 10.1021/np1002065.

50.

Nhatrangins A and B, aplysiatoxin-related metabolites from the marine cyanobacterium Lyngbya majuscula from Vietnam.

Chlipala GE, Pham HT, Nguyen VH, Krunic A, Shim SH, Soejarto DD, Orjala J.

J Nat Prod. 2010 Apr 23;73(4):784-7. doi: 10.1021/np100002q.

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