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Items: 1 to 50 of 145

1.

Neutrophils instruct homeostatic and pathological states in naive tissues.

Casanova-Acebes M, Nicolás-Ávila JA, Li JL, García-Silva S, Balachander A, Rubio-Ponce A, Weiss LA, Adrover JM, Burrows K, A-González N, Ballesteros I, Devi S, Quintana JA, Crainiciuc G, Leiva M, Gunzer M, Weber C, Nagasawa T, Soehnlein O, Merad M, Mortha A, Ng LG, Peinado H, Hidalgo A.

J Exp Med. 2018 Nov 5;215(11):2778-2795. doi: 10.1084/jem.20181468. Epub 2018 Oct 3.

PMID:
30282719
2.

A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding.

Baaten CCFMJ, Meacham S, de Witt SM, Feijge MAH, Adams DJ, Akkerman JN, Cosemans JMEM, Grassi L, Jupe S, Kostadima M, Mattheij NJA, Prins MH, Ramirez-Solis R, Soehnlein O, Swieringa F, Weber C, White JK, Ouwehand WH, Heemskerk JWM.

Blood. 2018 Oct 1. pii: blood-2018-02-831982. doi: 10.1182/blood-2018-02-831982. [Epub ahead of print]

PMID:
30275110
3.

Nutritional Modulation of Innate Immunity: The Fat-Bile-Gut Connection.

Chevre R, Silvestre-Roig C, Soehnlein O.

Trends Endocrinol Metab. 2018 Oct;29(10):686-698. doi: 10.1016/j.tem.2018.08.002. Epub 2018 Sep 6. Review.

PMID:
30197155
4.

The potential of chronopharmacology for treatment of atherosclerosis.

Winter C, Soehnlein O.

Curr Opin Lipidol. 2018 Oct;29(5):368-374. doi: 10.1097/MOL.0000000000000545.

PMID:
30063471
5.

Double-Strand DNA Sensing Aim2 Inflammasome Regulates Atherosclerotic Plaque Vulnerability.

Paulin N, Viola JR, Maas SL, de Jong R, Fernandes-Alnemri T, Weber C, Drechsler M, Döring Y, Soehnlein O.

Circulation. 2018 Jul 17;138(3):321-323. doi: 10.1161/CIRCULATIONAHA.117.033098. No abstract available.

PMID:
30012706
6.

A Pad 4 Plaque Erosion.

Soehnlein O, Bazioti V, Westerterp M.

Circ Res. 2018 Jun 22;123(1):6-8. doi: 10.1161/CIRCRESAHA.118.313110. No abstract available.

PMID:
29929967
7.

Deletion of MFGE8 Inhibits Neointima Formation upon Arterial Damage.

Viola JR, Lemnitzer P, Paulin N, Drechsler M, Nazari-Jahantigh M, Maas S, De Jong RJ, Winter J, Schober A, Weber C, Atabai K, Soehnlein O.

Thromb Haemost. 2018 Jul;118(7):1340-1342. doi: 10.1055/s-0038-1649522. Epub 2018 Jun 4. No abstract available.

PMID:
29864782
8.

Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis.

Winter C, Silvestre-Roig C, Ortega-Gomez A, Lemnitzer P, Poelman H, Schumski A, Winter J, Drechsler M, de Jong R, Immler R, Sperandio M, Hristov M, Zeller T, Nicolaes GAF, Weber C, Viola JR, Hidalgo A, Scheiermann C, Soehnlein O.

Cell Metab. 2018 Jul 3;28(1):175-182.e5. doi: 10.1016/j.cmet.2018.05.002. Epub 2018 May 31.

PMID:
29861387
9.

TIMPing the Aorta: Smooth Muscle Cell-Specific Deletion of BMAL1 Limits Murine Abdominal Aortic Aneurysm Development.

Winter C, Soehnlein O, Maegdefessel L.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):982-983. doi: 10.1161/ATVBAHA.118.310857. No abstract available.

PMID:
29695531
10.

Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation.

Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C.

Nat Commun. 2018 Apr 18;9(1):1523. doi: 10.1038/s41467-018-03925-2.

11.

The Ins and Outs of Myeloid Cells in Atherosclerosis.

Schumski A, Winter C, Döring Y, Soehnlein O.

J Innate Immun. 2018 Apr 18. doi: 10.1159/000488091. [Epub ahead of print]

12.

Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis.

Rami M, Guillamat-Prats R, Rinne P, Salvermoser M, Ring L, Bianchini M, Blanchet X, Megens RTA, Döring Y, Walzog B, Soehnlein O, Weber C, Faussner A, Steffens S.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):1007-1019. doi: 10.1161/ATVBAHA.117.310536. Epub 2018 Mar 22.

PMID:
29567680
13.

Myosin 1f is specifically required for neutrophil migration in 3D environments during acute inflammation.

Salvermoser M, Pick R, Weckbach LT, Zehrer A, Löhr P, Drechsler M, Sperandio M, Soehnlein O, Walzog B.

Blood. 2018 Apr 26;131(17):1887-1898. doi: 10.1182/blood-2017-10-811851. Epub 2018 Feb 27.

PMID:
29487067
14.

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.

Seijkens TTP, van Tiel CM, Kusters PJH, Atzler D, Soehnlein O, Zarzycka B, Aarts SABM, Lameijer M, Gijbels MJ, Beckers L, den Toom M, Slütter B, Kuiper J, Duchene J, Aslani M, Megens RTA, van 't Veer C, Kooij G, Schrijver R, Hoeksema MA, Boon L, Fay F, Tang J, Baxter S, Jongejan A, Moerland PD, Vriend G, Bleijlevens B, Fisher EA, Duivenvoorden R, Gerdes N, de Winther MPJ, Nicolaes GA, Mulder WJM, Weber C, Lutgens E.

J Am Coll Cardiol. 2018 Feb 6;71(5):527-542. doi: 10.1016/j.jacc.2017.11.055.

15.

[Atherothrombosis : Novel therapeutic strategies].

Soehnlein O.

Herz. 2018 Mar;43(2):103-108. doi: 10.1007/s00059-017-4659-x. German.

PMID:
29236146
16.

Decision shaping neutrophil-platelet interplay in inflammation: From physiology to intervention.

Soehnlein O.

Eur J Clin Invest. 2018 Feb;48(2). doi: 10.1111/eci.12871. Epub 2017 Dec 28. Review.

PMID:
29226390
17.

Functional ex-vivo Imaging of Arterial Cellular Recruitment and Lipid Extravasation.

van der Vorst EPC, Maas SL, Ortega-Gomez A, Hameleers JMM, Bianchini M, Asare Y, Soehnlein O, Döring Y, Weber C, Megens RTA.

Bio Protoc. 2017 Jun 20;7(12). pii: 2344. doi: 10.21769/BioProtoc.2344.

18.

Basic research: Standardizing animal atherosclerosis studies to improve reproducibility.

Soehnlein O, Silvestre-Roig C.

Nat Rev Cardiol. 2017 Oct;14(10):574-575. doi: 10.1038/nrcardio.2017.132. Epub 2017 Sep 7. No abstract available.

PMID:
28880022
19.

Ly6Chigh Monocytes Oscillate in the Heart During Homeostasis and After Myocardial Infarction-Brief Report.

Schloss MJ, Hilby M, Nitz K, Guillamat Prats R, Ferraro B, Leoni G, Soehnlein O, Kessler T, He W, Luckow B, Horckmans M, Weber C, Duchene J, Steffens S.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1640-1645. doi: 10.1161/ATVBAHA.117.309259. Epub 2017 Jun 29.

PMID:
28663258
20.

Corrigendum: Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Häger C, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy KM, Adams RH, Weber C, Limbourg FP.

Nat Commun. 2017 May 3;8:15486. doi: 10.1038/ncomms15486. No abstract available.

21.

Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies.

Döring Y, Noels H, van der Vorst EPC, Neideck C, Egea V, Drechsler M, Mandl M, Pawig L, Jansen Y, Schröder K, Bidzhekov K, Megens RTA, Theelen W, Klinkhammer BM, Boor P, Schurgers L, van Gorp R, Ries C, Kusters PJH, van der Wal A, Hackeng TM, Gäbel G, Brandes RP, Soehnlein O, Lutgens E, Vestweber D, Teupser D, Holdt LM, Rader DJ, Saleheen D, Weber C.

Circulation. 2017 Jul 25;136(4):388-403. doi: 10.1161/CIRCULATIONAHA.117.027646. Epub 2017 Apr 27.

22.

Circadian Control of Inflammatory Processes in Atherosclerosis and Its Complications.

Steffens S, Winter C, Schloss MJ, Hidalgo A, Weber C, Soehnlein O.

Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1022-1028. doi: 10.1161/ATVBAHA.117.309374. Epub 2017 Apr 27. Review.

PMID:
28450299
23.

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

von Hundelshausen P, Agten SM, Eckardt V, Blanchet X, Schmitt MM, Ippel H, Neideck C, Bidzhekov K, Leberzammer J, Wichapong K, Faussner A, Drechsler M, Grommes J, van Geffen JP, Li H, Ortega-Gomez A, Megens RT, Naumann R, Dijkgraaf I, Nicolaes GA, Döring Y, Soehnlein O, Lutgens E, Heemskerk JW, Koenen RR, Mayo KH, Hackeng TM, Weber C.

Sci Transl Med. 2017 Apr 5;9(384). pii: eaah6650. doi: 10.1126/scitranslmed.aah6650.

PMID:
28381538
24.

Neutrophils as protagonists and targets in chronic inflammation.

Soehnlein O, Steffens S, Hidalgo A, Weber C.

Nat Rev Immunol. 2017 Apr;17(4):248-261. doi: 10.1038/nri.2017.10. Epub 2017 Mar 13. Review.

PMID:
28287106
25.

Neutrophil Extracellular Traps in Atherosclerosis and Atherothrombosis.

Döring Y, Soehnlein O, Weber C.

Circ Res. 2017 Feb 17;120(4):736-743. doi: 10.1161/CIRCRESAHA.116.309692. Review.

PMID:
28209798
26.

Neutrophils orchestrate post-myocardial infarction healing by polarizing macrophages towards a reparative phenotype.

Horckmans M, Ring L, Duchene J, Santovito D, Schloss MJ, Drechsler M, Weber C, Soehnlein O, Steffens S.

Eur Heart J. 2017 Jan 14;38(3):187-197. doi: 10.1093/eurheartj/ehw002.

PMID:
28158426
27.

Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance.

Paulin N, Döring Y, Kooijman S, Blanchet X, Viola JR, de Jong R, Mandl M, Hendrikse J, Schiener M, von Hundelshausen P, Vogt A, Weber C, Bdeir K, Hofmann SM, Rensen PCN, Drechsler M, Soehnlein O.

EBioMedicine. 2017 Feb;16:204-211. doi: 10.1016/j.ebiom.2017.01.006. Epub 2017 Jan 7.

28.

Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report.

de Jong RJ, Paulin N, Lemnitzer P, Viola JR, Winter C, Ferraro B, Grommes J, Weber C, Reutelingsperger C, Drechsler M, Soehnlein O.

Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):312-315. doi: 10.1161/ATVBAHA.116.308744. Epub 2016 Dec 29.

PMID:
28062503
29.

The advantageous role of annexin A1 in cardiovascular disease.

de Jong R, Leoni G, Drechsler M, Soehnlein O.

Cell Adh Migr. 2017 May 4;11(3):261-274. doi: 10.1080/19336918.2016.1259059. Epub 2016 Nov 18. Review.

30.

Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment.

Ortega-Gomez A, Salvermoser M, Rossaint J, Pick R, Brauner J, Lemnitzer P, Tilgner J, de Jong RJ, Megens RT, Jamasbi J, Döring Y, Pham CT, Scheiermann C, Siess W, Drechsler M, Weber C, Grommes J, Zarbock A, Walzog B, Soehnlein O.

Circulation. 2016 Oct 18;134(16):1176-1188. Epub 2016 Sep 22.

31.

Inhibition of NET Release Fails to Reduce Adipose Tissue Inflammation in Mice.

Braster Q, Silvestre Roig C, Hartwig H, Beckers L, den Toom M, Döring Y, Daemen MJ, Lutgens E, Soehnlein O.

PLoS One. 2016 Oct 4;11(10):e0163922. doi: 10.1371/journal.pone.0163922. eCollection 2016.

32.

Aspirin, but Not Tirofiban Displays Protective Effects in Endotoxin Induced Lung Injury.

Tilgner J, von Trotha KT, Gombert A, Jacobs MJ, Drechsler M, Döring Y, Soehnlein O, Grommes J.

PLoS One. 2016 Sep 1;11(9):e0161218. doi: 10.1371/journal.pone.0161218. eCollection 2016.

33.

Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy KM, Adams RH, Weber C, Limbourg FP.

Nat Commun. 2016 Aug 31;7:12597. doi: 10.1038/ncomms12597.

34.

Monocytes Chat With Atherosclerotic Lesions.

Soehnlein O.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1720-1. doi: 10.1161/ATVBAHA.116.308176. No abstract available.

PMID:
27559145
35.

Resolving Lipid Mediators Maresin 1 and Resolvin D2 Prevent Atheroprogression in Mice.

Viola JR, Lemnitzer P, Jansen Y, Csaba G, Winter C, Neideck C, Silvestre-Roig C, Dittmar G, Döring Y, Drechsler M, Weber C, Zimmer R, Cenac N, Soehnlein O.

Circ Res. 2016 Oct 14;119(9):1030-1038. Epub 2016 Aug 16.

PMID:
27531933
36.

The time-of-day of myocardial infarction onset affects healing through oscillations in cardiac neutrophil recruitment.

Schloss MJ, Horckmans M, Nitz K, Duchene J, Drechsler M, Bidzhekov K, Scheiermann C, Weber C, Soehnlein O, Steffens S.

EMBO Mol Med. 2016 Aug 1;8(8):937-48. doi: 10.15252/emmm.201506083. Print 2016 Aug.

37.

Neutrophil heterogeneity: implications for homeostasis and pathogenesis.

Silvestre-Roig C, Hidalgo A, Soehnlein O.

Blood. 2016 May 5;127(18):2173-81. doi: 10.1182/blood-2016-01-688887. Epub 2016 Mar 21. Review.

38.

Cathelicidin regulates myeloid cell accumulation in adipose tissue and promotes insulin resistance during obesity.

Braster Q, Silvestre-Roig C, Hartwig H, Kusters P, Aarts S, den Toom M, Gallo RL, Weber C, Lutgens E, Soehnlein O.

Thromb Haemost. 2016 Jun 2;115(6):1237-9. doi: 10.1160/TH16-02-0112. Epub 2016 Mar 3. No abstract available.

PMID:
26939624
39.

Structure-Based Design of Peptidic Inhibitors of the Interaction between CC Chemokine Ligand 5 (CCL5) and Human Neutrophil Peptides 1 (HNP1).

Wichapong K, Alard JE, Ortega-Gomez A, Weber C, Hackeng TM, Soehnlein O, Nicolaes GA.

J Med Chem. 2016 May 12;59(9):4289-301. doi: 10.1021/acs.jmedchem.5b01952. Epub 2016 Feb 23.

PMID:
26871718
40.

Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes.

Gerdes N, Seijkens T, Lievens D, Kuijpers MJ, Winkels H, Projahn D, Hartwig H, Beckers L, Megens RT, Boon L, Noelle RJ, Soehnlein O, Heemskerk JW, Weber C, Lutgens E.

Arterioscler Thromb Vasc Biol. 2016 Mar;36(3):482-90. doi: 10.1161/ATVBAHA.115.307074. Epub 2016 Jan 28.

PMID:
26821950
41.

Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5.

Alard JE, Ortega-Gomez A, Wichapong K, Bongiovanni D, Horckmans M, Megens RT, Leoni G, Ferraro B, Rossaint J, Paulin N, Ng J, Ippel H, Suylen D, Hinkel R, Blanchet X, Gaillard F, D'Amico M, von Hundelshausen P, Zarbock A, Scheiermann C, Hackeng TM, Steffens S, Kupatt C, Nicolaes GA, Weber C, Soehnlein O.

Sci Transl Med. 2015 Dec 9;7(317):317ra196. doi: 10.1126/scitranslmed.aad5330.

PMID:
26659570
42.

Atherosclerotic Plaque Destabilization in Mice: A Comparative Study.

Hartwig H, Silvestre-Roig C, Hendrikse J, Beckers L, Paulin N, Van der Heiden K, Braster Q, Drechsler M, Daemen MJ, Lutgens E, Soehnlein O.

PLoS One. 2015 Oct 22;10(10):e0141019. doi: 10.1371/journal.pone.0141019. eCollection 2015.

43.

Intravital Microscopy for Atherosclerosis Research.

Megens RT, Soehnlein O.

Methods Mol Biol. 2015;1339:41-60. doi: 10.1007/978-1-4939-2929-0_3. Review.

PMID:
26445780
44.

Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired β2 integrin function in mice.

Klapproth S, Sperandio M, Pinheiro EM, Prünster M, Soehnlein O, Gertler FB, Fässler R, Moser M.

Blood. 2015 Dec 17;126(25):2704-12. doi: 10.1182/blood-2015-05-647453. Epub 2015 Sep 3.

45.

Neutrophil-macrophage interplay in atherosclerosis: protease-mediated cytokine processing versus NET release.

Soehnlein O, Ortega-Gómez A, Döring Y, Weber C.

Thromb Haemost. 2015 Oct;114(4):866-7. doi: 10.1160/TH15-08-0623. Epub 2015 Aug 27. No abstract available.

PMID:
26310276
46.

Evaluation of the BDCA2-DTR Transgenic Mouse Model in Chronic and Acute Inflammation.

Mandl M, Drechsler M, Jansen Y, Neideck C, Noels H, Faussner A, Soehnlein O, Weber C, Döring Y.

PLoS One. 2015 Aug 7;10(8):e0134176. doi: 10.1371/journal.pone.0134176. eCollection 2015.

47.

Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility.

Medina I, Cougoule C, Drechsler M, Bermudez B, Koenen RR, Sluimer J, Wolfs I, Döring Y, Herias V, Gijbels M, Bot I, de Jager S, Weber C, Cleutjens J, van Berkel TJC, Sikkink KJ, Mócsai A, Maridonneau-Parini I, Soehnlein O, Biessen EAL.

Circulation. 2015 Aug 11;132(6):490-501. doi: 10.1161/CIRCULATIONAHA.114.012316. Epub 2015 Jun 11.

48.

The Anti-Microbial Peptide LL-37/CRAMP Is Elevated in Patients with Liver Diseases and Acts as a Protective Factor during Mouse Liver Injury.

Wertenbruch S, Drescher H, Grossarth V, Kroy D, Giebeler A, Erschfeld S, Heinrichs D, Soehnlein O, Trautwein C, Brandenburg LO, Streetz K.

Digestion. 2015;91(4):307-17. doi: 10.1159/000368304. Epub 2015 May 13.

PMID:
25998843
49.

Atherosclerosis - A matter of unresolved inflammation.

Viola J, Soehnlein O.

Semin Immunol. 2015 May;27(3):184-93. doi: 10.1016/j.smim.2015.03.013. Epub 2015 Apr 10. Review.

PMID:
25865626
50.

Chemokines control mobilization, recruitment, and fate of monocytes in atherosclerosis.

Drechsler M, Duchene J, Soehnlein O.

Arterioscler Thromb Vasc Biol. 2015 May;35(5):1050-5. doi: 10.1161/ATVBAHA.114.304649. Epub 2015 Mar 19. Review.

PMID:
25792446

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