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Items: 1 to 50 of 162

1.

Artery-Associated Sympathetic Innervation Drives Rhythmic Vascular Inflammation of Arteries and Veins.

de Juan A, Ince LM, Pick R, Chen CS, Molica F, Zuchtriegel G, Wang C, Zhang D, Druzd D, Hessenauer MET, Pelli G, Kolbe I, Oster H, Prophete C, Hergenhan SM, Albrecht U, Ripperger J, Montanez E, Reichel CA, Soehnlein O, Kwak BR, Frenette PS, Scheiermann C.

Circulation. 2019 Aug 12. doi: 10.1161/CIRCULATIONAHA.119.040232. [Epub ahead of print]

PMID:
31401849
2.

Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis.

Fisslthaler B, Zippel N, Abdel Malik R, Delgado Lagos F, Zukunft S, Thoele J, Siuda D, Soehnlein O, Wittig I, Heidler J, Weigert A, Fleming I.

Int J Mol Sci. 2019 Jun 19;20(12). pii: E3005. doi: 10.3390/ijms20123005.

3.

Tick saliva protein Evasin-3 modulates chemotaxis by disrupting CXCL8 interactions with glycosaminoglycans and CXCR2.

Denisov SS, Ippel JH, Heinzmann ACA, Koenen RR, Ortega-Gomez A, Soehnlein O, Hackeng TM, Dijkgraaf I.

J Biol Chem. 2019 Aug 16;294(33):12370-12379. doi: 10.1074/jbc.RA119.008902. Epub 2019 Jun 24.

4.

Heparinoid sevuparin inhibits Streptococcus-induced vascular leak through neutralizing neutrophil-derived proteins.

Rasmuson J, Kenne E, Wahlgren M, Soehnlein O, Lindbom L.

FASEB J. 2019 Sep;33(9):10443-10452. doi: 10.1096/fj.201900627R. Epub 2019 Jun 19.

PMID:
31216421
5.

Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair.

Ferraro B, Leoni G, Hinkel R, Ormanns S, Paulin N, Ortega-Gomez A, Viola JR, de Jong R, Bongiovanni D, Bozoglu T, Maas SL, D'Amico M, Kessler T, Zeller T, Hristov M, Reutelingsperger C, Sager HB, Döring Y, Nahrendorf M, Kupatt C, Soehnlein O.

J Am Coll Cardiol. 2019 Jun 18;73(23):2990-3002. doi: 10.1016/j.jacc.2019.03.503.

6.

Biological Roles of Neutrophil-Derived Granule Proteins and Cytokines.

Cassatella MA, Östberg NK, Tamassia N, Soehnlein O.

Trends Immunol. 2019 Jul;40(7):648-664. doi: 10.1016/j.it.2019.05.003. Epub 2019 May 30. Review.

PMID:
31155315
7.

Neutrophil Research, Quo Vadis?

Soehnlein O.

Trends Immunol. 2019 Jul;40(7):561-564. doi: 10.1016/j.it.2019.04.011. Epub 2019 May 24.

PMID:
31133465
8.

Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.

Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gómez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, González-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O.

Nature. 2019 May;569(7755):236-240. doi: 10.1038/s41586-019-1167-6. Epub 2019 May 1.

PMID:
31043745
9.

Mechanistic Links between Non-Coding RNAs and Myeloid Cell Inflammation in Atherosclerosis.

Paloschi V, Winter H, Viola J, Soehnlein O, Maegdefessel L.

Thromb Haemost. 2019 Aug;119(8):1205-1211. doi: 10.1055/s-0039-1687874. Epub 2019 Apr 29.

PMID:
31035303
10.

Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions-Brief Report.

van der Vorst EPC, Mandl M, Müller M, Neideck C, Jansen Y, Hristov M, Gencer S, Peters LJF, Meiler S, Feld M, Geiselhöringer AL, de Jong RJ, Ohnmacht C, Noels H, Soehnlein O, Drechsler M, Weber C, Döring Y.

Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):685-693. doi: 10.1161/ATVBAHA.119.312386.

PMID:
30786742
11.

Therapeutic Targeting of Neutrophil Extracellular Traps in Atherogenic Inflammation.

Van Avondt K, Maegdefessel L, Soehnlein O.

Thromb Haemost. 2019 Apr;119(4):542-552. doi: 10.1055/s-0039-1678664. Epub 2019 Feb 7. Review.

PMID:
30731493
12.

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.

Adrover JM, Del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibáñez B, Hidalgo A.

Immunity. 2019 Feb 19;50(2):390-402.e10. doi: 10.1016/j.immuni.2019.01.002. Epub 2019 Jan 29.

PMID:
30709741
13.

Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation.

Cremer S, Michalik KM, Fischer A, Pfisterer L, Jaé N, Winter C, Boon RA, Muhly-Reinholz M, John D, Uchida S, Weber C, Poller W, Günther S, Braun T, Li DY, Maegdefessel L, Perisic Matic L, Hedin U, Soehnlein O, Zeiher A, Dimmeler S.

Circulation. 2019 Mar 5;139(10):1320-1334. doi: 10.1161/CIRCULATIONAHA.117.029015. Erratum in: Circulation. 2019 Jul 16;140(3):e161.

PMID:
30586743
14.

Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2 V617F Mice.

Wang W, Liu W, Fidler T, Wang Y, Tang Y, Woods B, Welch C, Cai B, Silvestre-Roig C, Ai D, Yang YG, Hidalgo A, Soehnlein O, Tabas I, Levine RL, Tall AR, Wang N.

Circ Res. 2018 Nov 9;123(11):e35-e47. doi: 10.1161/CIRCRESAHA.118.313283.

PMID:
30571460
15.

Organ-Specific Mechanisms of Transendothelial Neutrophil Migration in the Lung, Liver, Kidney, and Aorta.

Maas SL, Soehnlein O, Viola JR.

Front Immunol. 2018 Nov 27;9:2739. doi: 10.3389/fimmu.2018.02739. eCollection 2018. Review.

16.

(Re) Solving Repair After Myocardial Infarction.

Leoni G, Soehnlein O.

Front Pharmacol. 2018 Nov 26;9:1342. doi: 10.3389/fphar.2018.01342. eCollection 2018.

17.

Endothelial NOD1 directs myeloid cell recruitment in atherosclerosis through VCAM-1.

González-Ramos S, Paz-García M, Rius C, Del Monte-Monge A, Rodríguez C, Fernández-García V, Andrés V, Martínez-González J, Lasunción MA, Martín-Sanz P, Soehnlein O, Boscá L.

FASEB J. 2019 Mar;33(3):3912-3921. doi: 10.1096/fj.201801231RR. Epub 2018 Nov 29.

PMID:
30496704
18.

Neutrophils instruct homeostatic and pathological states in naive tissues.

Casanova-Acebes M, Nicolás-Ávila JA, Li JL, García-Silva S, Balachander A, Rubio-Ponce A, Weiss LA, Adrover JM, Burrows K, A-González N, Ballesteros I, Devi S, Quintana JA, Crainiciuc G, Leiva M, Gunzer M, Weber C, Nagasawa T, Soehnlein O, Merad M, Mortha A, Ng LG, Peinado H, Hidalgo A.

J Exp Med. 2018 Nov 5;215(11):2778-2795. doi: 10.1084/jem.20181468. Epub 2018 Oct 3.

19.

A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding.

Baaten CCFMJ, Meacham S, de Witt SM, Feijge MAH, Adams DJ, Akkerman JN, Cosemans JMEM, Grassi L, Jupe S, Kostadima M, Mattheij NJA, Prins MH, Ramirez-Solis R, Soehnlein O, Swieringa F, Weber C, White JK, Ouwehand WH, Heemskerk JWM.

Blood. 2018 Dec 13;132(24):e35-e46. doi: 10.1182/blood-2018-02-831982. Epub 2018 Oct 1. Review.

PMID:
30275110
20.

Nutritional Modulation of Innate Immunity: The Fat-Bile-Gut Connection.

Chevre R, Silvestre-Roig C, Soehnlein O.

Trends Endocrinol Metab. 2018 Oct;29(10):686-698. doi: 10.1016/j.tem.2018.08.002. Epub 2018 Sep 6. Review.

PMID:
30197155
21.

The potential of chronopharmacology for treatment of atherosclerosis.

Winter C, Soehnlein O.

Curr Opin Lipidol. 2018 Oct;29(5):368-374. doi: 10.1097/MOL.0000000000000545.

PMID:
30063471
22.

Double-Strand DNA Sensing Aim2 Inflammasome Regulates Atherosclerotic Plaque Vulnerability.

Paulin N, Viola JR, Maas SL, de Jong R, Fernandes-Alnemri T, Weber C, Drechsler M, Döring Y, Soehnlein O.

Circulation. 2018 Jul 17;138(3):321-323. doi: 10.1161/CIRCULATIONAHA.117.033098. No abstract available.

PMID:
30012706
23.

A Pad 4 Plaque Erosion.

Soehnlein O, Bazioti V, Westerterp M.

Circ Res. 2018 Jun 22;123(1):6-8. doi: 10.1161/CIRCRESAHA.118.313110. No abstract available.

PMID:
29929967
24.

Deletion of MFGE8 Inhibits Neointima Formation upon Arterial Damage.

Viola JR, Lemnitzer P, Paulin N, Drechsler M, Nazari-Jahantigh M, Maas S, De Jong RJ, Winter J, Schober A, Weber C, Atabai K, Soehnlein O.

Thromb Haemost. 2018 Jul;118(7):1340-1342. doi: 10.1055/s-0038-1649522. Epub 2018 Jun 4. No abstract available.

PMID:
29864782
25.

Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis.

Winter C, Silvestre-Roig C, Ortega-Gomez A, Lemnitzer P, Poelman H, Schumski A, Winter J, Drechsler M, de Jong R, Immler R, Sperandio M, Hristov M, Zeller T, Nicolaes GAF, Weber C, Viola JR, Hidalgo A, Scheiermann C, Soehnlein O.

Cell Metab. 2018 Jul 3;28(1):175-182.e5. doi: 10.1016/j.cmet.2018.05.002. Epub 2018 May 31.

26.

TIMPing the Aorta: Smooth Muscle Cell-Specific Deletion of BMAL1 Limits Murine Abdominal Aortic Aneurysm Development.

Winter C, Soehnlein O, Maegdefessel L.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):982-983. doi: 10.1161/ATVBAHA.118.310857. No abstract available.

PMID:
29695531
27.

Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation.

Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C.

Nat Commun. 2018 Apr 18;9(1):1523. doi: 10.1038/s41467-018-03925-2.

28.

The Ins and Outs of Myeloid Cells in Atherosclerosis.

Schumski A, Winter C, Döring Y, Soehnlein O.

J Innate Immun. 2018;10(5-6):479-486. doi: 10.1159/000488091. Epub 2018 Apr 18. Review.

29.

Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis.

Rami M, Guillamat-Prats R, Rinne P, Salvermoser M, Ring L, Bianchini M, Blanchet X, Megens RTA, Döring Y, Walzog B, Soehnlein O, Weber C, Faussner A, Steffens S.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):1007-1019. doi: 10.1161/ATVBAHA.117.310536. Epub 2018 Mar 22.

PMID:
29567680
30.

Myosin 1f is specifically required for neutrophil migration in 3D environments during acute inflammation.

Salvermoser M, Pick R, Weckbach LT, Zehrer A, Löhr P, Drechsler M, Sperandio M, Soehnlein O, Walzog B.

Blood. 2018 Apr 26;131(17):1887-1898. doi: 10.1182/blood-2017-10-811851. Epub 2018 Feb 27.

31.

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.

Seijkens TTP, van Tiel CM, Kusters PJH, Atzler D, Soehnlein O, Zarzycka B, Aarts SABM, Lameijer M, Gijbels MJ, Beckers L, den Toom M, Slütter B, Kuiper J, Duchene J, Aslani M, Megens RTA, van 't Veer C, Kooij G, Schrijver R, Hoeksema MA, Boon L, Fay F, Tang J, Baxter S, Jongejan A, Moerland PD, Vriend G, Bleijlevens B, Fisher EA, Duivenvoorden R, Gerdes N, de Winther MPJ, Nicolaes GA, Mulder WJM, Weber C, Lutgens E.

J Am Coll Cardiol. 2018 Feb 6;71(5):527-542. doi: 10.1016/j.jacc.2017.11.055.

32.

[Atherothrombosis : Novel therapeutic strategies].

Soehnlein O.

Herz. 2018 Mar;43(2):103-108. doi: 10.1007/s00059-017-4659-x. Review. German.

PMID:
29236146
33.

Decision shaping neutrophil-platelet interplay in inflammation: From physiology to intervention.

Soehnlein O.

Eur J Clin Invest. 2018 Feb;48(2). doi: 10.1111/eci.12871. Epub 2017 Dec 28. Review.

PMID:
29226390
34.

Functional ex-vivo Imaging of Arterial Cellular Recruitment and Lipid Extravasation.

van der Vorst EPC, Maas SL, Ortega-Gomez A, Hameleers JMM, Bianchini M, Asare Y, Soehnlein O, Döring Y, Weber C, Megens RTA.

Bio Protoc. 2017 Jun 20;7(12). pii: 2344. doi: 10.21769/BioProtoc.2344.

35.

Basic research: Standardizing animal atherosclerosis studies to improve reproducibility.

Soehnlein O, Silvestre-Roig C.

Nat Rev Cardiol. 2017 Oct;14(10):574-575. doi: 10.1038/nrcardio.2017.132. Epub 2017 Sep 7. No abstract available.

PMID:
28880022
36.

Ly6Chigh Monocytes Oscillate in the Heart During Homeostasis and After Myocardial Infarction-Brief Report.

Schloss MJ, Hilby M, Nitz K, Guillamat Prats R, Ferraro B, Leoni G, Soehnlein O, Kessler T, He W, Luckow B, Horckmans M, Weber C, Duchene J, Steffens S.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1640-1645. doi: 10.1161/ATVBAHA.117.309259. Epub 2017 Jun 29.

PMID:
28663258
37.

Corrigendum: Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Häger C, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy KM, Adams RH, Weber C, Limbourg FP.

Nat Commun. 2017 May 3;8:15486. doi: 10.1038/ncomms15486. No abstract available.

38.

Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies.

Döring Y, Noels H, van der Vorst EPC, Neideck C, Egea V, Drechsler M, Mandl M, Pawig L, Jansen Y, Schröder K, Bidzhekov K, Megens RTA, Theelen W, Klinkhammer BM, Boor P, Schurgers L, van Gorp R, Ries C, Kusters PJH, van der Wal A, Hackeng TM, Gäbel G, Brandes RP, Soehnlein O, Lutgens E, Vestweber D, Teupser D, Holdt LM, Rader DJ, Saleheen D, Weber C.

Circulation. 2017 Jul 25;136(4):388-403. doi: 10.1161/CIRCULATIONAHA.117.027646. Epub 2017 Apr 27.

39.

Circadian Control of Inflammatory Processes in Atherosclerosis and Its Complications.

Steffens S, Winter C, Schloss MJ, Hidalgo A, Weber C, Soehnlein O.

Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1022-1028. doi: 10.1161/ATVBAHA.117.309374. Epub 2017 Apr 27. Review.

PMID:
28450299
40.

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

von Hundelshausen P, Agten SM, Eckardt V, Blanchet X, Schmitt MM, Ippel H, Neideck C, Bidzhekov K, Leberzammer J, Wichapong K, Faussner A, Drechsler M, Grommes J, van Geffen JP, Li H, Ortega-Gomez A, Megens RT, Naumann R, Dijkgraaf I, Nicolaes GA, Döring Y, Soehnlein O, Lutgens E, Heemskerk JW, Koenen RR, Mayo KH, Hackeng TM, Weber C.

Sci Transl Med. 2017 Apr 5;9(384). pii: eaah6650. doi: 10.1126/scitranslmed.aah6650.

PMID:
28381538
41.

Neutrophils as protagonists and targets in chronic inflammation.

Soehnlein O, Steffens S, Hidalgo A, Weber C.

Nat Rev Immunol. 2017 Apr;17(4):248-261. doi: 10.1038/nri.2017.10. Epub 2017 Mar 13. Review.

PMID:
28287106
42.

Neutrophil Extracellular Traps in Atherosclerosis and Atherothrombosis.

Döring Y, Soehnlein O, Weber C.

Circ Res. 2017 Feb 17;120(4):736-743. doi: 10.1161/CIRCRESAHA.116.309692. Review.

PMID:
28209798
43.

Neutrophils orchestrate post-myocardial infarction healing by polarizing macrophages towards a reparative phenotype.

Horckmans M, Ring L, Duchene J, Santovito D, Schloss MJ, Drechsler M, Weber C, Soehnlein O, Steffens S.

Eur Heart J. 2017 Jan 14;38(3):187-197. doi: 10.1093/eurheartj/ehw002.

PMID:
28158426
44.

Human Neutrophil Peptide 1 Limits Hypercholesterolemia-induced Atherosclerosis by Increasing Hepatic LDL Clearance.

Paulin N, Döring Y, Kooijman S, Blanchet X, Viola JR, de Jong R, Mandl M, Hendrikse J, Schiener M, von Hundelshausen P, Vogt A, Weber C, Bdeir K, Hofmann SM, Rensen PCN, Drechsler M, Soehnlein O.

EBioMedicine. 2017 Feb;16:204-211. doi: 10.1016/j.ebiom.2017.01.006. Epub 2017 Jan 7.

45.

Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report.

de Jong RJ, Paulin N, Lemnitzer P, Viola JR, Winter C, Ferraro B, Grommes J, Weber C, Reutelingsperger C, Drechsler M, Soehnlein O.

Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):312-315. doi: 10.1161/ATVBAHA.116.308744. Epub 2016 Dec 29.

PMID:
28062503
46.

The advantageous role of annexin A1 in cardiovascular disease.

de Jong R, Leoni G, Drechsler M, Soehnlein O.

Cell Adh Migr. 2017 May 4;11(3):261-274. doi: 10.1080/19336918.2016.1259059. Epub 2016 Nov 18. Review.

47.

Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment.

Ortega-Gomez A, Salvermoser M, Rossaint J, Pick R, Brauner J, Lemnitzer P, Tilgner J, de Jong RJ, Megens RT, Jamasbi J, Döring Y, Pham CT, Scheiermann C, Siess W, Drechsler M, Weber C, Grommes J, Zarbock A, Walzog B, Soehnlein O.

Circulation. 2016 Oct 18;134(16):1176-1188. Epub 2016 Sep 22.

48.

Inhibition of NET Release Fails to Reduce Adipose Tissue Inflammation in Mice.

Braster Q, Silvestre Roig C, Hartwig H, Beckers L, den Toom M, Döring Y, Daemen MJ, Lutgens E, Soehnlein O.

PLoS One. 2016 Oct 4;11(10):e0163922. doi: 10.1371/journal.pone.0163922. eCollection 2016.

49.

Aspirin, but Not Tirofiban Displays Protective Effects in Endotoxin Induced Lung Injury.

Tilgner J, von Trotha KT, Gombert A, Jacobs MJ, Drechsler M, Döring Y, Soehnlein O, Grommes J.

PLoS One. 2016 Sep 1;11(9):e0161218. doi: 10.1371/journal.pone.0161218. eCollection 2016.

50.

Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy KM, Adams RH, Weber C, Limbourg FP.

Nat Commun. 2016 Aug 31;7:12597. doi: 10.1038/ncomms12597.

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