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Items: 1 to 50 of 63

1.

SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair.

Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H.

Nat Commun. 2019 Sep 6;10(1):4042. doi: 10.1038/s41467-019-11880-9.

2.

Ep400 deficiency in Schwann cells causes persistent expression of early developmental regulators and peripheral neuropathy.

Fröb F, Sock E, Tamm ER, Saur AL, Hillgärtner S, Williams TJ, Fujii T, Fukunaga R, Wegner M.

Nat Commun. 2019 May 29;10(1):2361. doi: 10.1038/s41467-019-10287-w.

3.

Transcriptional control of myelination and remyelination.

Sock E, Wegner M.

Glia. 2019 Nov;67(11):2153-2165. doi: 10.1002/glia.23636. Epub 2019 Apr 30. Review.

PMID:
31038810
4.

Phosphorylation of the neurogenic transcription factor SOX11 on serine 133 modulates neuronal morphogenesis.

Balta EA, Schäffner I, Wittmann MT, Sock E, von Zweydorf F, von Wittgenstein J, Steib K, Heim B, Kremmer E, Häberle BM, Ueffing M, Lie DC, Gloeckner CJ.

Sci Rep. 2018 Nov 1;8(1):16196. doi: 10.1038/s41598-018-34480-x.

5.

Characterization of Glomerular Sox9+ Cells in Anti-Glomerular Basement Membrane Nephritis in the Rat.

Prochnicki A, Amann K, Wegner M, Sock E, Pfister E, Shankland S, Pippin J, Daniel C.

Am J Pathol. 2018 Nov;188(11):2529-2541. doi: 10.1016/j.ajpath.2018.07.023. Epub 2018 Sep 7.

PMID:
30201496
6.

Transcription factor profiling identifies Sox9 as regulator of proliferation and differentiation in corneal epithelial stem/progenitor cells.

Menzel-Severing J, Zenkel M, Polisetti N, Sock E, Wegner M, Kruse FE, Schlötzer-Schrehardt U.

Sci Rep. 2018 Jul 6;8(1):10268. doi: 10.1038/s41598-018-28596-3.

7.

Phosphorylation Modulates the Subcellular Localization of SOX11.

Balta EA, Wittmann MT, Jung M, Sock E, Haeberle BM, Heim B, von Zweydorf F, Heppt J, von Wittgenstein J, Gloeckner CJ, Lie DC.

Front Mol Neurosci. 2018 Jun 19;11:211. doi: 10.3389/fnmol.2018.00211. eCollection 2018.

8.

Striking parallels between carotid body glomus cell and adrenal chromaffin cell development.

Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ, Brown N, Reese J, Baker CVH.

Dev Biol. 2018 Dec 1;444 Suppl 1:S308-S324. doi: 10.1016/j.ydbio.2018.05.016. Epub 2018 May 25.

9.

The transcription factor prospero homeobox protein 1 is a direct target of SoxC proteins during developmental vertebrate neurogenesis.

Jacob A, Wüst HM, Thalhammer JM, Fröb F, Küspert M, Reiprich S, Balta EA, Lie DC, Wegner M, Sock E.

J Neurochem. 2018 Aug;146(3):251-268. doi: 10.1111/jnc.14456.

10.

Publisher Correction: Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning.

Weider M, Starost LJ, Groll K, Küspert M, Sock E, Wedel M, Fröb F, Schmitt C, Baroti T, Hartwig AC, Hillgärtner S, Piefke S, Fadler T, Ehrlich M, Ehlert C, Stehling M, Albrecht S, Jabali A, Schöler HR, Winkler J, Kuhlmann T, Wegner M.

Nat Commun. 2018 Apr 23;9(1):1667. doi: 10.1038/s41467-018-03871-z.

11.

Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning.

Weider M, Starost LJ, Groll K, Küspert M, Sock E, Wedel M, Fröb F, Schmitt C, Baroti T, Hartwig AC, Hillgärtner S, Piefke S, Fadler T, Ehrlich M, Ehlert C, Stehling M, Albrecht S, Jabali A, Schöler HR, Winkler J, Kuhlmann T, Wegner M.

Nat Commun. 2018 Mar 2;9(1):899. doi: 10.1038/s41467-018-03336-3. Erratum in: Nat Commun. 2018 Apr 23;9(1):1667.

12.

Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT).

Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A.

Kidney Int. 2018 May;93(5):1142-1153. doi: 10.1016/j.kint.2017.11.026. Epub 2018 Feb 17.

13.

Analysis of the human SOX10 mutation Q377X in mice and its implications for genotype-phenotype correlation in SOX10-related human disease.

Truch K, Arter J, Turnescu T, Weider M, Hartwig AC, Tamm ER, Sock E, Wegner M.

Hum Mol Genet. 2018 Mar 15;27(6):1078-1092. doi: 10.1093/hmg/ddy029.

PMID:
29361054
14.

Sp2 is the only glutamine-rich specificity protein with minor impact on development and differentiation in myelinating glia.

Wegener A, Küspert M, Sock E, Philipsen S, Suske G, Wegner M.

J Neurochem. 2017 Jan;140(2):245-256. doi: 10.1111/jnc.13908. Epub 2016 Dec 20.

15.

The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes.

Muth KN, Piefke S, Weider M, Sock E, Hermans-Borgmeyer I, Wegner M, Küspert M.

Glia. 2016 Dec;64(12):2120-2132. doi: 10.1002/glia.23044. Epub 2016 Aug 17.

PMID:
27532821
16.

Orchestration of Neuronal Differentiation and Progenitor Pool Expansion in the Developing Cortex by SoxC Genes.

Chen C, Lee GA, Pourmorady A, Sock E, Donoghue MJ.

J Neurosci. 2015 Jul 22;35(29):10629-42. doi: 10.1523/JNEUROSCI.1663-15.2015.

17.

Copy number variation of two separate regulatory regions upstream of SOX9 causes isolated 46,XY or 46,XX disorder of sex development.

Kim GJ, Sock E, Buchberger A, Just W, Denzer F, Hoepffner W, German J, Cole T, Mann J, Seguin JH, Zipf W, Costigan C, Schmiady H, Rostásy M, Kramer M, Kaltenbach S, Rösler B, Georg I, Troppmann E, Teichmann AC, Salfelder A, Widholz SA, Wieacker P, Hiort O, Camerino G, Radi O, Wegner M, Arnold HH, Scherer G.

J Med Genet. 2015 Apr;52(4):240-7. doi: 10.1136/jmedgenet-2014-102864. Epub 2015 Jan 20.

PMID:
25604083
18.

Sox5 controls dorsal progenitor and interneuron specification in the spinal cord.

Quiroga AC, Stolt CC, Diez del Corral R, Dimitrov S, Pérez-Alcalá S, Sock E, Barbas JA, Wegner M, Morales AV.

Dev Neurobiol. 2015 May;75(5):522-38. doi: 10.1002/dneu.22240. Epub 2014 Nov 13.

19.

Dysfunction of spatacsin leads to axonal pathology in SPG11-linked hereditary spastic paraplegia.

Pérez-Brangulí F, Mishra HK, Prots I, Havlicek S, Kohl Z, Saul D, Rummel C, Dorca-Arevalo J, Regensburger M, Graef D, Sock E, Blasi J, Groemer TW, Schlötzer-Schrehardt U, Winkler J, Winner B.

Hum Mol Genet. 2014 Sep 15;23(18):4859-74. doi: 10.1093/hmg/ddu200. Epub 2014 May 2.

20.

Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types.

Paul MH, Harvey RP, Wegner M, Sock E.

Cell Mol Life Sci. 2014 Aug;71(15):2931-45. doi: 10.1007/s00018-013-1523-x. Epub 2013 Dec 6.

PMID:
24310815
21.

Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells.

Doddrell RD, Dun XP, Shivane A, Feltri ML, Wrabetz L, Wegner M, Sock E, Hanemann CO, Parkinson DB.

Brain. 2013 Feb;136(Pt 2):549-63. doi: 10.1093/brain/aws353.

22.

The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells.

Usui A, Mochizuki Y, Iida A, Miyauchi E, Satoh S, Sock E, Nakauchi H, Aburatani H, Murakami A, Wegner M, Watanabe S.

Development. 2013 Feb;140(4):740-50. doi: 10.1242/dev.090274. Epub 2013 Jan 14.

23.

SoxC transcription factors are required for neuronal differentiation in adult hippocampal neurogenesis.

Mu L, Berti L, Masserdotti G, Covic M, Michaelidis TM, Doberauer K, Merz K, Rehfeld F, Haslinger A, Wegner M, Sock E, Lefebvre V, Couillard-Despres S, Aigner L, Berninger B, Lie DC.

J Neurosci. 2012 Feb 29;32(9):3067-80. doi: 10.1523/JNEUROSCI.4679-11.2012.

24.

Impaired spleen formation perturbs morphogenesis of the gastric lobe of the pancreas.

Hörnblad A, Eriksson AU, Sock E, Hill RE, Ahlgren U.

PLoS One. 2011;6(6):e21753. doi: 10.1371/journal.pone.0021753. Epub 2011 Jun 30.

25.

Effect of the ethanolic extract from Fagara tessmannii on testicular function, sex reproductive organs and hormone level in adult male rats.

Massoma Lembè D, Gasco M, Rubio J, Yucra S, Sock EN, Gonzales GF.

Andrologia. 2011 Apr;43(2):139-44. doi: 10.1111/j.1439-0272.2009.01035.x. Epub 2011 Feb 25. Erratum in: Andrologia. 2016 Apr;48(3):360.

PMID:
21382068
26.

SOX9 controls epithelial branching by activating RET effector genes during kidney development.

Reginensi A, Clarkson M, Neirijnck Y, Lu B, Ohyama T, Groves AK, Sock E, Wegner M, Costantini F, Chaboissier MC, Schedl A.

Hum Mol Genet. 2011 Mar 15;20(6):1143-53. doi: 10.1093/hmg/ddq558. Epub 2011 Jan 6.

27.

Sox11 regulates survival and axonal growth of embryonic sensory neurons.

Lin L, Lee VM, Wang Y, Lin JS, Sock E, Wegner M, Lei L.

Dev Dyn. 2011 Jan;240(1):52-64. doi: 10.1002/dvdy.22489.

28.

The closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord development.

Thein DC, Thalhammer JM, Hartwig AC, Crenshaw EB 3rd, Lefebvre V, Wegner M, Sock E.

J Neurochem. 2010 Oct;115(1):131-41. doi: 10.1111/j.1471-4159.2010.06910.x. Epub 2010 Aug 3.

29.

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors.

Bhattaram P, Penzo-Méndez A, Sock E, Colmenares C, Kaneko KJ, Vassilev A, Depamphilis ML, Wegner M, Lefebvre V.

Nat Commun. 2010 Apr 12;1:9. doi: 10.1038/ncomms1008.

30.

Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system.

Potzner MR, Tsarovina K, Binder E, Penzo-Méndez A, Lefebvre V, Rohrer H, Wegner M, Sock E.

Development. 2010 Mar;137(5):775-84. doi: 10.1242/dev.042101.

31.

Replacement of mouse Sox10 by the Drosophila ortholog Sox100B provides evidence for co-option of SoxE proteins into vertebrate-specific gene-regulatory networks through altered expression.

Cossais F, Sock E, Hornig J, Schreiner S, Kellerer S, Bösl MR, Russell S, Wegner M.

Dev Biol. 2010 May 1;341(1):267-81. doi: 10.1016/j.ydbio.2010.01.038. Epub 2010 Feb 6.

32.

Evolutionary conserved sequence elements with embryonic enhancer activity in the vicinity of the mammalian Sox8 gene.

Guth SI, Bösl MR, Sock E, Wegner M.

Int J Biochem Cell Biol. 2010 Mar;42(3):465-71. doi: 10.1016/j.biocel.2009.07.008. Epub 2009 Jul 26.

PMID:
19638316
33.

Replacement of related POU transcription factors leads to severe defects in mouse forebrain development.

Wolf M, Lommes P, Sock E, Reiprich S, Friedrich RP, Kriesch J, Stolt CC, Bermingham JR Jr, Wegner M.

Dev Biol. 2009 Aug 15;332(2):418-28. doi: 10.1016/j.ydbio.2009.06.011. Epub 2009 Jun 13.

34.

Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors.

Hoser M, Potzner MR, Koch JM, Bösl MR, Wegner M, Sock E.

Mol Cell Biol. 2008 Aug;28(15):4675-87. doi: 10.1128/MCB.00338-08. Epub 2008 May 27.

35.

Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11.

Wurm A, Sock E, Fuchshofer R, Wegner M, Tamm ER.

Exp Eye Res. 2008 Jun;86(6):895-907. doi: 10.1016/j.exer.2008.03.004. Epub 2008 Mar 12.

PMID:
18423449
36.

Prolonged Sox4 expression in oligodendrocytes interferes with normal myelination in the central nervous system.

Potzner MR, Griffel C, Lütjen-Drecoll E, Bösl MR, Wegner M, Sock E.

Mol Cell Biol. 2007 Aug;27(15):5316-26. Epub 2007 May 21.

37.

Prolonged glial expression of Sox4 in the CNS leads to architectural cerebellar defects and ataxia.

Hoser M, Baader SL, Bösl MR, Ihmer A, Wegner M, Sock E.

J Neurosci. 2007 May 16;27(20):5495-505.

38.

SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function.

Stolt CC, Schlierf A, Lommes P, Hillgärtner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M.

Dev Cell. 2006 Nov;11(5):697-709.

39.

The POU protein Oct-6 is a nucleocytoplasmic shuttling protein.

Baranek C, Sock E, Wegner M.

Nucleic Acids Res. 2005 Oct 31;33(19):6277-86. Print 2005.

40.

Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord.

Stolt CC, Schmitt S, Lommes P, Sock E, Wegner M.

Dev Biol. 2005 May 15;281(2):309-17.

41.

The high mobility group transcription factor Sox8 is a negative regulator of osteoblast differentiation.

Schmidt K, Schinke T, Haberland M, Priemel M, Schilling AF, Mueldner C, Rueger JM, Sock E, Wegner M, Amling M.

J Cell Biol. 2005 Mar 14;168(6):899-910. Epub 2005 Mar 7.

42.

Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling.

Sock E, Rettig SD, Enderich J, Bösl MR, Tamm ER, Wegner M.

Mol Cell Biol. 2004 Aug;24(15):6635-44.

43.

The Sox9 transcription factor determines glial fate choice in the developing spinal cord.

Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M.

Genes Dev. 2003 Jul 1;17(13):1677-89.

44.

Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia.

Sock E, Pagon RA, Keymolen K, Lissens W, Wegner M, Scherer G.

Hum Mol Genet. 2003 Jun 15;12(12):1439-47.

PMID:
12783851
45.

Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8.

Sock E, Schmidt K, Hermanns-Borgmeyer I, Bösl MR, Wegner M.

Mol Cell Biol. 2001 Oct;21(20):6951-9.

46.

Interaction among SOX10, PAX3 and MITF, three genes altered in Waardenburg syndrome.

Bondurand N, Pingault V, Goerich DE, Lemort N, Sock E, Le Caignec C, Wegner M, Goossens M.

Hum Mol Genet. 2000 Aug 12;9(13):1907-17.

PMID:
10942418
48.

Functional analysis of Sox10 mutations found in human Waardenburg-Hirschsprung patients.

Kuhlbrodt K, Schmidt C, Sock E, Pingault V, Bondurand N, Goossens M, Wegner M.

J Biol Chem. 1998 Sep 4;273(36):23033-8.

49.

Cooperative function of POU proteins and SOX proteins in glial cells.

Kuhlbrodt K, Herbarth B, Sock E, Enderich J, Hermans-Borgmeyer I, Wegner M.

J Biol Chem. 1998 Jun 26;273(26):16050-7.

50.

Sox10, a novel transcriptional modulator in glial cells.

Kuhlbrodt K, Herbarth B, Sock E, Hermans-Borgmeyer I, Wegner M.

J Neurosci. 1998 Jan 1;18(1):237-50.

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