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Items: 1 to 50 of 235

1.

Negatively charged amino acids at the foot-and-mouth disease virus capsid reduce the virion-destabilizing effect of viral RNA at acidic pH.

Caridi F, López-Argüello S, Rodríguez-Huete A, Torres E, Bustos MJ, Cañas-Arranz R, Martín-Acebes MA, Mateu MG, Sobrino F.

Sci Rep. 2020 Feb 3;10(1):1657. doi: 10.1038/s41598-020-58414-8.

2.

A bivalent B-cell epitope dendrimer peptide can confer long-lasting immunity in swine against foot-and-mouth disease.

Cañas-Arranz R, Forner M, Defaus S, Rodríguez-Pulido M, de León P, Torres E, Bustos MJ, Borrego B, Sáiz M, Blanco E, Andreu D, Sobrino F.

Transbound Emerg Dis. 2020 Jan 28. doi: 10.1111/tbed.13497. [Epub ahead of print]

PMID:
31994334
3.

A Single Dose of Dendrimer B2T Peptide Vaccine Partially Protects Pigs against Foot-and-Mouth Disease Virus Infection.

Cañas-Arranz R, Forner M, Defaus S, de León P, Bustos MJ, Torres E, Sobrino F, Andreu D, Blanco E.

Vaccines (Basel). 2020 Jan 10;8(1). pii: E19. doi: 10.3390/vaccines8010019.

4.

Clinical Infections by Herpesviruses in Patients Treated with Valproic Acid: A Nested Case-Control Study in the Spanish Primary Care Database, BIFAP.

Gil M, González-González R, Vázquez-Calvo A, Álvarez-Gutiérrez A, Martín-Acebes MA, Praena B, Bello-Morales R, Saiz JC, López-Guerrero JA, Tabarés E, Sobrino F.

J Clin Med. 2019 Sep 11;8(9). pii: E1442. doi: 10.3390/jcm8091442.

5.

Inhibition of Porcine Viruses by Different Cell-Targeted Antiviral Drugs.

de León P, Bustos MJ, Torres E, Cañas-Arranz R, Sobrino F, Carrascosa AL.

Front Microbiol. 2019 Aug 14;10:1853. doi: 10.3389/fmicb.2019.01853. eCollection 2019.

6.

Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models.

Jiménez de Oya N, Esler WP, Huard K, El-Kattan AF, Karamanlidis G, Blázquez AB, Ramos-Ibeas P, Escribano-Romero E, Louloudes-Lázaro A, Casas J, Sobrino F, Hoehn K, James DE, Gutiérrez-Adán A, Saiz JC, Martín-Acebes MA.

Emerg Microbes Infect. 2019;8(1):624-636. doi: 10.1080/22221751.2019.1604084.

7.

Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.

de la Higuera I, Ferrer-Orta C, Moreno E, de Ávila AI, Soria ME, Singh K, Caridi F, Sobrino F, Sarafianos SG, Perales C, Verdaguer N, Domingo E.

J Virol. 2018 Sep 26;92(20). pii: e01119-18. doi: 10.1128/JVI.01119-18. Print 2018 Oct 15.

8.

Synthetic RNA derived from the foot-and-mouth disease virus genome elicits antiviral responses in bovine and porcine cells through IRF3 activation.

Rodríguez Pulido M, Del Amo L, Sobrino F, Sáiz M.

Vet Microbiol. 2018 Jul;221:8-12. doi: 10.1016/j.vetmic.2018.05.015. Epub 2018 May 24.

PMID:
29981712
9.

Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virus.

Rodríguez Pulido M, Sánchez-Aparicio MT, Martínez-Salas E, García-Sastre A, Sobrino F, Sáiz M.

PLoS Pathog. 2018 Jun 29;14(6):e1007135. doi: 10.1371/journal.ppat.1007135. eCollection 2018 Jun.

10.

Immune Response and Partial Protection against Heterologous Foot-and-Mouth Disease Virus Induced by Dendrimer Peptides in Cattle.

Soria I, Quattrocchi V, Langellotti C, Pérez-Filgueira M, Pega J, Gnazzo V, Romera S, Schammas J, Bucafusco D, Di Giacomo S, de la Torre BG, Andreu D, Sobrino F, Blanco E, Zamorano P.

J Immunol Res. 2018 Apr 18;2018:3497401. doi: 10.1155/2018/3497401. eCollection 2018.

11.

Relationship between dental occlusion and functional dependence in elderly Caucasians.

Diz P, Cardoso M, Diniz-Freitas M, Vázquez P, Sobrino F, Limeres J.

Oral Dis. 2018 Mar;24(1-2):33-37. doi: 10.1111/odi.12723.

PMID:
29480609
12.

Curcumin enhances LXRα in an AMP-activated protein kinase-dependent manner in human macrophages.

Sáenz J, Alba G, Reyes-Quiroz ME, Geniz I, Jiménez J, Sobrino F, Santa-María C.

J Nutr Biochem. 2018 Apr;54:48-56. doi: 10.1016/j.jnutbio.2017.11.006. Epub 2017 Nov 16.

PMID:
29242172
13.

Grapefruit Flavonoid Naringenin Regulates the Expression of LXRα in THP-1 Macrophages by Modulating AMP-Activated Protein Kinase.

Saenz J, Santa-María C, Reyes-Quiroz ME, Geniz I, Jiménez J, Sobrino F, Alba G.

Mol Pharm. 2018 May 7;15(5):1735-1745. doi: 10.1021/acs.molpharmaceut.7b00797. Epub 2018 Apr 19.

PMID:
29140707
14.

Dendrimeric peptides can confer protection against foot-and-mouth disease virus in cattle.

Soria I, Quattrocchi V, Langellotti C, Gammella M, Digiacomo S, Garcia de la Torre B, Andreu D, Montoya M, Sobrino F, Blanco E, Zamorano P.

PLoS One. 2017 Sep 26;12(9):e0185184. doi: 10.1371/journal.pone.0185184. eCollection 2017.

15.

Overuse Injuries in Professional Ballet: Influence of Age and Years of Professional Practice.

Sobrino FJ, Guillén P.

Orthop J Sports Med. 2017 Jun 28;5(6):2325967117712704. doi: 10.1177/2325967117712704. eCollection 2017 Jun.

16.

Preserved immunogenicity of an inactivated vaccine based on foot-and-mouth disease virus particles with improved stability.

Caridi F, Vázquez-Calvo Á, Borrego B, McCullough K, Summerfield A, Sobrino F, Martín-Acebes MA.

Vet Microbiol. 2017 May;203:275-279. doi: 10.1016/j.vetmic.2017.03.031. Epub 2017 Mar 30.

PMID:
28619156
17.

A bivalent dendrimeric peptide bearing a T-cell epitope from foot-and-mouth disease virus protein 3A improves humoral response against classical swine fever virus.

Bohórquez JA, Defaus S, Muñoz-González S, Perez-Simó M, Rosell R, Fraile L, Sobrino F, Andreu D, Ganges L.

Virus Res. 2017 Jun 15;238:8-12. doi: 10.1016/j.virusres.2017.05.020. Epub 2017 May 30.

PMID:
28571760
18.

Combined administration of synthetic RNA and a conventional vaccine improves immune responses and protection against foot-and-mouth disease virus in swine.

Borrego B, Blanco E, Rodríguez Pulido M, Mateos F, Lorenzo G, Cardillo S, Smitsaart E, Sobrino F, Sáiz M.

Antiviral Res. 2017 Jun;142:30-36. doi: 10.1016/j.antiviral.2017.03.009. Epub 2017 Mar 16.

PMID:
28315707
19.

Equine Rhinitis A Virus Mutants with Altered Acid Resistance Unveil a Key Role of VP3 and Intrasubunit Interactions in the Control of the pH Stability of the Aphthovirus Capsid.

Caridi F, Cañas-Arranz R, Vázquez-Calvo A, Sobrino F, Martín-Acebes MA.

J Virol. 2016 Oct 14;90(21):9725-9732. doi: 10.1128/JVI.01043-16. Print 2016 Nov 1.

20.

Platelet-activating factor and hydrogen peroxide exert a dual modulatory effect on the transcription of LXRα and its target genes in human neutrophils.

Reyes-Quiroz ME, Alba G, Sáenz J, Geniz I, Jiménez J, Martín-Nieto J, Santa-María C, Sobrino F.

Int Immunopharmacol. 2016 Sep;38:357-66. doi: 10.1016/j.intimp.2016.05.001. Epub 2016 Jun 25.

PMID:
27351826
21.

The Amino Acid Substitution Q65H in the 2C Protein of Swine Vesicular Disease Virus Confers Resistance to Golgi Disrupting Drugs.

Vázquez-Calvo Á, Caridi F, González-Magaldi M, Saiz JC, Sobrino F, Martín-Acebes MA.

Front Microbiol. 2016 Apr 27;7:612. doi: 10.3389/fmicb.2016.00612. eCollection 2016.

22.

A recombinant DNA vaccine protects mice deficient in the alpha/beta interferon receptor against lethal challenge with Usutu virus.

Martín-Acebes MA, Blázquez AB, Cañas-Arranz R, Vázquez-Calvo Á, Merino-Ramos T, Escribano-Romero E, Sobrino F, Saiz JC.

Vaccine. 2016 Apr 19;34(18):2066-73. doi: 10.1016/j.vaccine.2016.03.015. Epub 2016 Mar 15.

PMID:
26993334
23.

Full protection of swine against foot-and-mouth disease by a bivalent B-cell epitope dendrimer peptide.

Blanco E, Guerra B, de la Torre BG, Defaus S, Dekker A, Andreu D, Sobrino F.

Antiviral Res. 2016 May;129:74-80. doi: 10.1016/j.antiviral.2016.03.005. Epub 2016 Mar 5.

PMID:
26956030
24.

First Complete Coding Sequence of a Spanish Isolate of Swine Vesicular Disease Virus.

Vázquez-Calvo Á, Saiz JC, Sobrino F, Martín-Acebes MA.

Genome Announc. 2016 Mar 3;4(2). pii: e01742-15. doi: 10.1128/genomeA.01742-15.

25.

Inhibition of herpes virus infection in oligodendrocyte cultured cells by valproic acid.

Crespillo AJ, Praena B, Bello-Morales R, Lerma L, Vázquez-Calvo A, Martín-Acebes MA, Tabarés E, Sobrino F, López-Guerrero JA.

Virus Res. 2016 Mar 2;214:71-9. doi: 10.1016/j.virusres.2016.01.009. Epub 2016 Jan 21.

PMID:
26805038
26.

Host sphingomyelin increases West Nile virus infection in vivo.

Martín-Acebes MA, Gabandé-Rodríguez E, García-Cabrero AM, Sánchez MP, Ledesma MD, Sobrino F, Saiz JC.

J Lipid Res. 2016 Mar;57(3):422-32. doi: 10.1194/jlr.M064212. Epub 2016 Jan 13.

27.

7-Keto-cholesterol and 25-hydroxy-1 cholesterol rapidly enhance ROS production in human neutrophils.

Alba G, Reyes-Quiróz ME, Sáenz J, Geniz I, Jiménez J, Martín-Nieto J, Pintado E, Sobrino F, Santa-María C.

Eur J Nutr. 2016 Dec;55(8):2485-2492. Epub 2015 Dec 29.

PMID:
26715521
28.

Overuse Injuries in Professional Ballet: Injury-Based Differences Among Ballet Disciplines.

Sobrino FJ, de la Cuadra C, Guillén P.

Orthop J Sports Med. 2015 Jun 26;3(6):2325967115590114. doi: 10.1177/2325967115590114. eCollection 2015 Jun.

29.

Peptides Interfering 3A Protein Dimerization Decrease FMDV Multiplication.

González-Magaldi M, Vázquez-Calvo Á, de la Torre BG, Valle J, Andreu D, Sobrino F.

PLoS One. 2015 Oct 27;10(10):e0141415. doi: 10.1371/journal.pone.0141415. eCollection 2015.

30.

Modification of the Host Cell Lipid Metabolism Induced by Hypolipidemic Drugs Targeting the Acetyl Coenzyme A Carboxylase Impairs West Nile Virus Replication.

Merino-Ramos T, Vázquez-Calvo Á, Casas J, Sobrino F, Saiz JC, Martín-Acebes MA.

Antimicrob Agents Chemother. 2015 Oct 26;60(1):307-15. doi: 10.1128/AAC.01578-15. Print 2016 Jan.

31.

Synthetic RNAs Mimicking Structural Domains in the Foot-and-Mouth Disease Virus Genome Elicit a Broad Innate Immune Response in Porcine Cells Triggered by RIG-I and TLR Activation.

Borrego B, Rodríguez-Pulido M, Revilla C, Álvarez B, Sobrino F, Domínguez J, Sáiz M.

Viruses. 2015 Jul 17;7(7):3954-73. doi: 10.3390/v7072807.

32.

Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.

Ferrer-Orta C, de la Higuera I, Caridi F, Sánchez-Aparicio MT, Moreno E, Perales C, Singh K, Sarafianos SG, Sobrino F, Domingo E, Verdaguer N.

J Virol. 2015 Jul;89(13):6848-59. doi: 10.1128/JVI.03283-14. Epub 2015 Apr 22.

33.

The pH Stability of Foot-and-Mouth Disease Virus Particles Is Modulated by Residues Located at the Pentameric Interface and in the N Terminus of VP1.

Caridi F, Vázquez-Calvo A, Sobrino F, Martín-Acebes MA.

J Virol. 2015 May;89(10):5633-42. doi: 10.1128/JVI.03358-14. Epub 2015 Mar 11.

34.

Membrane topology and cellular dynamics of foot-and-mouth disease virus 3A protein.

González-Magaldi M, Martín-Acebes MA, Kremer L, Sobrino F.

PLoS One. 2014 Oct 2;9(9):e106685. doi: 10.1371/journal.pone.0106685. eCollection 2014.

35.

Protection of a single dose west nile virus recombinant subviral particle vaccine against lineage 1 or 2 strains and analysis of the cross-reactivity with Usutu virus.

Merino-Ramos T, Blázquez AB, Escribano-Romero E, Cañas-Arranz R, Sobrino F, Saiz JC, Martín-Acebes MA.

PLoS One. 2014 Sep 17;9(9):e108056. doi: 10.1371/journal.pone.0108056. eCollection 2014.

36.

The composition of West Nile virus lipid envelope unveils a role of sphingolipid metabolism in flavivirus biogenesis.

Martín-Acebes MA, Merino-Ramos T, Blázquez AB, Casas J, Escribano-Romero E, Sobrino F, Saiz JC.

J Virol. 2014 Oct;88(20):12041-54. doi: 10.1128/JVI.02061-14. Epub 2014 Aug 13.

37.

Protection against Rift Valley fever virus infection in mice upon administration of interferon-inducing RNA transcripts from the FMDV genome.

Lorenzo G, Rodríguez-Pulido M, López-Gil E, Sobrino F, Borrego B, Sáiz M, Brun A.

Antiviral Res. 2014 Sep;109:64-7. doi: 10.1016/j.antiviral.2014.06.010. Epub 2014 Jun 25.

PMID:
24973761
38.

Oleic acid modulates mRNA expression of liver X receptor (LXR) and its target genes ABCA1 and SREBP1c in human neutrophils.

Reyes-Quiroz ME, Alba G, Saenz J, Santa-María C, Geniz I, Jiménez J, Ramírez R, Martín-Nieto J, Pintado E, Sobrino F.

Eur J Nutr. 2014 Dec;53(8):1707-17. doi: 10.1007/s00394-014-0677-0. Epub 2014 Apr 11.

PMID:
24722912
39.

B epitope multiplicity and B/T epitope orientation influence immunogenicity of foot-and-mouth disease peptide vaccines.

Blanco E, Cubillos C, Moreno N, Bárcena J, de la Torre BG, Andreu D, Sobrino F.

Clin Dev Immunol. 2013;2013:475960. doi: 10.1155/2013/475960. Epub 2013 Dec 3.

40.

An increase in acid resistance of foot-and-mouth disease virus capsid is mediated by a tyrosine replacement of the VP2 histidine previously associated with VP0 cleavage.

Vázquez-Calvo A, Caridi F, Sobrino F, Martín-Acebes MA.

J Virol. 2014 Mar;88(5):3039-42. doi: 10.1128/JVI.03222-13. Epub 2013 Dec 18.

41.

Platelet-activating factor downregulates the expression of liver X receptor-α and its target genes in human neutrophils.

Reyes-Quiroz ME, Alba G, Santa-María C, Saenz J, Geniz I, Jiménez J, Ramírez R, Martín-Nieto J, Pintado E, Sobrino F.

FEBS J. 2014 Feb;281(3):970-82. doi: 10.1111/febs.12662. Epub 2014 Jan 2.

42.

Characterization of a nuclear localization signal in the foot-and-mouth disease virus polymerase.

Sanchez-Aparicio MT, Rosas MF, Sobrino F.

Virology. 2013 Sep;444(1-2):203-10. doi: 10.1016/j.virol.2013.06.011. Epub 2013 Jul 22.

43.

Delivery of synthetic RNA can enhance the immunogenicity of vaccines against foot-and-mouth disease virus (FMDV) in mice.

Borrego B, Rodríguez-Pulido M, Mateos F, de la Losa N, Sobrino F, Sáiz M.

Vaccine. 2013 Sep 13;31(40):4375-81. doi: 10.1016/j.vaccine.2013.07.008. Epub 2013 Jul 13.

PMID:
23859841
44.

Latin American consensus on guidelines for chronic migraine treatment.

Giacomozzi AR, Vindas AP, Silva AA Jr, Bordini CA, Buonanotte CF, Roesler CA, Brito CM, Perez C, Carvalho Dde S, Macedo DD, Piovesan EJ, Sarmento EM, Melhado EM, Éckeli FD, Kowacs F, Sobrino F, Rabello GD, Rada G, Souza JA, Casanovas JR, Durán JC, Calia LC, Medina LR, Queiroz LP, Ciciarelli MC, Valença MM, Cusicanqui M, Jimenez MK, Goycochea MT, Peres MF, Sandoval MV, Vincent MB, Gomes MV, Diez M, Aranaga N, Barrientos N, Kowacs PA, Filho PF.

Arq Neuropsiquiatr. 2013 Jul;71(7):478-86. doi: 10.1590/0004-282X20130066.

45.

Inhibition of multiplication of the prototypic arenavirus LCMV by valproic acid.

Vázquez-Calvo Á, Martín-Acebes MA, Sáiz JC, Ngo N, Sobrino F, de la Torre JC.

Antiviral Res. 2013 Aug;99(2):172-9. doi: 10.1016/j.antiviral.2013.05.012. Epub 2013 Jun 2.

46.

Protection against West Nile virus infection in mice after inoculation with type I interferon-inducing RNA transcripts.

Rodríguez-Pulido M, Martín-Acebes MA, Escribano-Romero E, Blázquez AB, Sobrino F, Borrego B, Sáiz M, Saiz JC.

PLoS One. 2012;7(11):e49494. doi: 10.1371/journal.pone.0049494. Epub 2012 Nov 14.

47.

Transcription of liver X receptor is down-regulated by 15-deoxy-Δ(12,14)-prostaglandin J(2) through oxidative stress in human neutrophils.

Alba G, Reyes ME, Santa-María C, Ramírez R, Geniz I, Jiménez J, Martín-Nieto J, Pintado E, Sobrino F.

PLoS One. 2012;7(10):e42195. doi: 10.1371/journal.pone.0042195. Epub 2012 Oct 24.

48.

Plasma membrane phosphatidylinositol 4,5 bisphosphate is required for internalization of foot-and-mouth disease virus and vesicular stomatitis virus.

Vázquez-Calvo A, Sobrino F, Martín-Acebes MA.

PLoS One. 2012;7(9):e45172. doi: 10.1371/journal.pone.0045172. Epub 2012 Sep 28.

49.

A T-cell epitope on NS3 non-structural protein enhances the B and T cell responses elicited by dendrimeric constructions against CSFV in domestic pigs.

Tarradas J, Monsó M, Fraile L, de la Torre BG, Muñoz M, Rosell R, Riquelme C, Pérez LJ, Nofrarías M, Domingo M, Sobrino F, Andreu D, Ganges L.

Vet Immunol Immunopathol. 2012 Nov 15;150(1-2):36-46. doi: 10.1016/j.vetimm.2012.08.006. Epub 2012 Aug 17.

PMID:
22959286
50.

Modulation of foot-and-mouth disease virus pH threshold for uncoating correlates with differential sensitivity to inhibition of cellular Rab GTPases and decreases infectivity in vivo.

Vázquez-Calvo Á, Caridi F, Rodriguez-Pulido M, Borrego B, Sáiz M, Sobrino F, Martín-Acebes MA.

J Gen Virol. 2012 Nov;93(Pt 11):2382-2386. doi: 10.1099/vir.0.045419-0. Epub 2012 Aug 8.

PMID:
22875255

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