Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 81

1.

Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.

Talavera A, Hendrix J, Versées W, Jurėnas D, Van Nerom K, Vandenberk N, Singh RK, Konijnenberg A, De Gieter S, Castro-Roa D, Barth A, De Greve H, Sobott F, Hofkens J, Zenkin N, Loris R, Garcia-Pino A.

Sci Adv. 2018 Mar 14;4(3):eaap9714. doi: 10.1126/sciadv.aap9714. eCollection 2018 Mar.

2.

Radical solutions: Principles and application of electron-based dissociation in mass spectrometry-based analysis of protein structure.

Lermyte F, Valkenborg D, Loo JA, Sobott F.

Mass Spectrom Rev. 2018 Feb 9. doi: 10.1002/mas.21560. [Epub ahead of print] Review.

PMID:
29425406
3.

Fixed-Charge Trimethyl Pyrilium Modification for Enabling Enhanced Top-Down Mass Spectrometry Sequencing of Intact Protein Complexes.

Polasky DA, Lermyte F, Nshanian M, Sobott F, Andrews PC, Loo JA, Ruotolo BT.

Anal Chem. 2018 Feb 20;90(4):2756-2764. doi: 10.1021/acs.analchem.7b04806. Epub 2018 Feb 2.

PMID:
29360341
4.

The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere.

Fisher GL, Pastrana CL, Higman VA, Koh A, Taylor JA, Butterer A, Craggs T, Sobott F, Murray H, Crump MP, Moreno-Herrero F, Dillingham MS.

Elife. 2017 Dec 15;6. pii: e28086. doi: 10.7554/eLife.28086.

5.

Evaluation of ion mobility for the separation of glycoconjugate isomers due to different types of sialic acid linkage, at the intact glycoprotein, glycopeptide and glycan level.

Barroso A, Giménez E, Konijnenberg A, Sancho J, Sanz-Nebot V, Sobott F.

J Proteomics. 2018 Feb 20;173:22-31. doi: 10.1016/j.jprot.2017.11.020. Epub 2017 Nov 29.

PMID:
29197583
6.

Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes.

Bruce HA, Du D, Matak-Vinkovic D, Bandyra KJ, Broadhurst RW, Martin E, Sobott F, Shkumatov AV, Luisi BF.

Nucleic Acids Res. 2018 Jan 9;46(1):387-402. doi: 10.1093/nar/gkx1083.

7.

A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover.

Deyaert E, Wauters L, Guaitoli G, Konijnenberg A, Leemans M, Terheyden S, Petrovic A, Gallardo R, Nederveen-Schippers LM, Athanasopoulos PS, Pots H, Van Haastert PJM, Sobott F, Gloeckner CJ, Efremov R, Kortholt A, Versées W.

Nat Commun. 2017 Oct 18;8(1):1008. doi: 10.1038/s41467-017-01103-4.

8.

Advances in native high-performance liquid chromatography and intact mass spectrometry for the characterization of biopharmaceutical products.

Tassi M, De Vos J, Chatterjee S, Sobott F, Bones J, Eeltink S.

J Sep Sci. 2018 Jan;41(1):125-144. doi: 10.1002/jssc.201700988. Epub 2017 Nov 2. Review.

PMID:
28990739
9.

Estimation of Rates of Reactions Triggered by Electron Transfer in Top-Down Mass Spectrometry.

Ciach MA, Łącki MK, Miasojedow B, Lermyte F, Valkenborg D, Sobott F, Gambin A.

J Comput Biol. 2018 Mar;25(3):282-301. doi: 10.1089/cmb.2017.0156. Epub 2017 Sep 25.

PMID:
28945460
10.

Apparent activation energies of protein-protein complex dissociation in the gas-phase determined by electrospray mass spectrometry.

Yefremova Y, Melder FTI, Danquah BD, Opuni KFM, Koy C, Ehrens A, Frommholz D, Illges H, Koelbel K, Sobott F, Glocker MO.

Anal Bioanal Chem. 2017 Nov;409(28):6549-6558. doi: 10.1007/s00216-017-0603-4. Epub 2017 Sep 12.

PMID:
28900708
11.
12.

Native Mass Spectrometry for the Characterization of Structure and Interactions of Membrane Proteins.

van Dyck JF, Konijnenberg A, Sobott F.

Methods Mol Biol. 2017;1635:205-232. doi: 10.1007/978-1-4939-7151-0_11.

PMID:
28755371
13.

Antarctic fish versus human cytoglobins - The same but yet so different.

Cuypers B, Vermeylen S, Hammerschmid D, Trashin S, Rahemi V, Konijnenberg A, De Schutter A, Cheng CC, Giordano D, Verde C, De Wael K, Sobott F, Dewilde S, Van Doorslaer S.

J Inorg Biochem. 2017 Aug;173:66-78. doi: 10.1016/j.jinorgbio.2017.04.025. Epub 2017 Apr 28.

PMID:
28501743
14.

Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1.

Heirbaut M, Lermyte F, Martin EM, Beelen S, Sobott F, Strelkov SV, Weeks SD.

J Biol Chem. 2017 Jun 16;292(24):9944-9957. doi: 10.1074/jbc.M116.773515. Epub 2017 May 9.

15.

Preprotein mature domains contain translocase targeting signals that are essential for secretion.

Chatzi KE, Sardis MF, Tsirigotaki A, Koukaki M, Šoštarić N, Konijnenberg A, Sobott F, Kalodimos CG, Karamanou S, Economou A.

J Cell Biol. 2017 May 1;216(5):1357-1369. doi: 10.1083/jcb.201609022. Epub 2017 Apr 12.

16.

AtaT blocks translation initiation by N-acetylation of the initiator tRNAfMet.

Jurėnas D, Chatterjee S, Konijnenberg A, Sobott F, Droogmans L, Garcia-Pino A, Van Melderen L.

Nat Chem Biol. 2017 Jun;13(6):640-646. doi: 10.1038/nchembio.2346. Epub 2017 Apr 3.

PMID:
28369041
17.

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.

Boeynaems S, Bogaert E, Kovacs D, Konijnenberg A, Timmerman E, Volkov A, Guharoy M, De Decker M, Jaspers T, Ryan VH, Janke AM, Baatsen P, Vercruysse T, Kolaitis RM, Daelemans D, Taylor JP, Kedersha N, Anderson P, Impens F, Sobott F, Schymkowitz J, Rousseau F, Fawzi NL, Robberecht W, Van Damme P, Tompa P, Van Den Bosch L.

Mol Cell. 2017 Mar 16;65(6):1044-1055.e5. doi: 10.1016/j.molcel.2017.02.013.

18.

Analyzing complex mixtures of drug-like molecules: Ion mobility as an adjunct to existing liquid chromatography-(tandem) mass spectrometry methods.

Boschmans J, Lemière F, Sobott F.

J Chromatogr A. 2017 Mar 24;1490:80-88. doi: 10.1016/j.chroma.2017.02.015. Epub 2017 Feb 14.

PMID:
28228233
19.

Proton Dynamics in Protein Mass Spectrometry.

Li J, Lyu W, Rossetti G, Konijnenberg A, Natalello A, Ippoliti E, Orozco M, Sobott F, Grandori R, Carloni P.

J Phys Chem Lett. 2017 Mar 16;8(6):1105-1112. doi: 10.1021/acs.jpclett.7b00127. Epub 2017 Feb 22.

PMID:
28207277
20.

Hidden States within Disordered Regions of the CcdA Antitoxin Protein.

Burger VM, Vandervelde A, Hendrix J, Konijnenberg A, Sobott F, Loris R, Stultz CM.

J Am Chem Soc. 2017 Feb 22;139(7):2693-2701. doi: 10.1021/jacs.6b11450. Epub 2017 Feb 8.

PMID:
28124913
21.

The preferential heterodimerization of human small heat shock proteins HSPB1 and HSPB6 is dictated by the N-terminal domain.

Heirbaut M, Lermyte F, Martin EM, Beelen S, Verschueren T, Sobott F, Strelkov SV, Weeks SD.

Arch Biochem Biophys. 2016 Nov 15;610:41-50. doi: 10.1016/j.abb.2016.10.002. Epub 2016 Oct 4.

PMID:
27717639
22.

Conformational Space and Stability of ETD Charge Reduction Products of Ubiquitin.

Lermyte F, Łącki MK, Valkenborg D, Gambin A, Sobott F.

J Am Soc Mass Spectrom. 2017 Jan;28(1):69-76. doi: 10.1007/s13361-016-1444-7. Epub 2016 Aug 5.

PMID:
27495285
23.

Gas-phase microsolvation of ubiquitin: investigation of crown ether complexation sites using ion mobility-mass spectrometry.

Göth M, Lermyte F, Schmitt XJ, Warnke S, von Helden G, Sobott F, Pagel K.

Analyst. 2016 Oct 7;141(19):5502-10. doi: 10.1039/c6an01377e. Epub 2016 Aug 5.

PMID:
27494002
24.

Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein.

Konijnenberg A, Ranica S, Narkiewicz J, Legname G, Grandori R, Sobott F, Natalello A.

Anal Chem. 2016 Sep 6;88(17):8468-75. doi: 10.1021/acs.analchem.6b00731. Epub 2016 Aug 12.

PMID:
27467405
25.

Development of a novel antibody-tetrazine conjugate for bioorthogonal pretargeting.

Maggi A, Ruivo E, Fissers J, Vangestel C, Chatterjee S, Joossens J, Sobott F, Staelens S, Stroobants S, Van Der Veken P, Wyffels L, Augustyns K.

Org Biomol Chem. 2016 Aug 21;14(31):7544-51. doi: 10.1039/c6ob01411a. Epub 2016 Jul 19.

PMID:
27431745
26.

Lipids modulate the conformational dynamics of a secondary multidrug transporter.

Martens C, Stein RA, Masureel M, Roth A, Mishra S, Dawaliby R, Konijnenberg A, Sobott F, Govaerts C, Mchaourab HS.

Nat Struct Mol Biol. 2016 Aug;23(8):744-51. doi: 10.1038/nsmb.3262. Epub 2016 Jul 11.

27.

ATP and autophosphorylation driven conformational changes of HipA kinase revealed by ion mobility and crosslinking mass spectrometry.

Wen Y, Sobott F, Devreese B.

Anal Bioanal Chem. 2016 Aug;408(21):5925-33. doi: 10.1007/s00216-016-9709-3. Epub 2016 Jun 20.

PMID:
27325463
28.

Combining density functional theory (DFT) and collision cross-section (CCS) calculations to analyze the gas-phase behaviour of small molecules and their protonation site isomers.

Boschmans J, Jacobs S, Williams JP, Palmer M, Richardson K, Giles K, Lapthorn C, Herrebout WA, Lemière F, Sobott F.

Analyst. 2016 Jun 20;141(13):4044-54. doi: 10.1039/c5an02456k.

PMID:
27264846
29.

Covalent adducts of melphalan with free amino acids and a model peptide studied by liquid chromatography/tandem mass spectrometry.

Dewaele D, Sobott F, Lemière F.

Rapid Commun Mass Spectrom. 2016 Mar 30;30(6):719-30. doi: 10.1002/rcm.7489.

PMID:
26864525
30.

Differences in the Elemental Isotope Definition May Lead to Errors in Modern Mass-Spectrometry-Based Proteomics.

Claesen J, Lermyte F, Sobott F, Burzykowski T, Valkenborg D.

Anal Chem. 2015 Nov 3;87(21):10747-54. doi: 10.1021/acs.analchem.5b01165. Epub 2015 Oct 22.

PMID:
26457653
31.

Extending native mass spectrometry approaches to integral membrane proteins.

Konijnenberg A, van Dyck JF, Kailing LL, Sobott F.

Biol Chem. 2015 Sep;396(9-10):991-1002. doi: 10.1515/hsz-2015-0136. Review.

PMID:
26352204
32.

Signal loss due to oligomerization in ELISA analysis of amyloid-beta can be recovered by a novel sample pre-treatment method.

Janssen L, Sobott F, De Deyn PP, Van Dam D.

MethodsX. 2015 Feb 27;2:112-23. doi: 10.1016/j.mex.2015.02.011. eCollection 2015.

33.

Electron transfer dissociation provides higher-order structural information of native and partially unfolded protein complexes.

Lermyte F, Sobott F.

Proteomics. 2015 Aug;15(16):2813-22. doi: 10.1002/pmic.201400516. Epub 2015 Jul 22.

PMID:
26081219
34.

Characterization of top-down ETD in a travelling-wave ion guide.

Lermyte F, Verschueren T, Brown JM, Williams JP, Valkenborg D, Sobott F.

Methods. 2015 Nov 1;89:22-9. doi: 10.1016/j.ymeth.2015.05.019. Epub 2015 May 23.

PMID:
26014039
35.

Bouncing off the Walls: Excited Protein Complexes Tell Their Story.

Konijnenberg A, Sobott F.

Chem Biol. 2015 May 21;22(5):563-4. doi: 10.1016/j.chembiol.2015.05.004.

36.

Top-down mass spectrometry of intact membrane protein complexes reveals oligomeric state and sequence information in a single experiment.

Konijnenberg A, Bannwarth L, Yilmaz D, Koçer A, Venien-Bryan C, Sobott F.

Protein Sci. 2015 Aug;24(8):1292-300. doi: 10.1002/pro.2703. Epub 2015 May 29.

37.

Extensive Charge Reduction and Dissociation of Intact Protein Complexes Following Electron Transfer on a Quadrupole-Ion Mobility-Time-of-Flight MS.

Lermyte F, Williams JP, Brown JM, Martin EM, Sobott F.

J Am Soc Mass Spectrom. 2015 Jul;26(7):1068-76. doi: 10.1007/s13361-015-1124-z. Epub 2015 Apr 11.

PMID:
25862188
38.

Protomers of benzocaine: solvent and permittivity dependence.

Warnke S, Seo J, Boschmans J, Sobott F, Scrivens JH, Bleiholder C, Bowers MT, Gewinner S, Schöllkopf W, Pagel K, von Helden G.

J Am Chem Soc. 2015 Apr 1;137(12):4236-42. doi: 10.1021/jacs.5b01338. Epub 2015 Mar 17.

PMID:
25760934
39.

Specific and non-specific interactions of ParB with DNA: implications for chromosome segregation.

Taylor JA, Pastrana CL, Butterer A, Pernstich C, Gwynn EJ, Sobott F, Moreno-Herrero F, Dillingham MS.

Nucleic Acids Res. 2015 Jan;43(2):719-31. doi: 10.1093/nar/gku1295. Epub 2015 Jan 8.

40.

Molecular basis for structural heterogeneity of an intrinsically disordered protein bound to a partner by combined ESI-IM-MS and modeling.

D'Urzo A, Konijnenberg A, Rossetti G, Habchi J, Li J, Carloni P, Sobott F, Longhi S, Grandori R.

J Am Soc Mass Spectrom. 2015 Mar;26(3):472-81. doi: 10.1007/s13361-014-1048-z. Epub 2014 Dec 16.

PMID:
25510932
41.

Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).

Bulatov E, Martin EM, Chatterjee S, Knebel A, Shimamura S, Konijnenberg A, Johnson C, Zinn N, Grandi P, Sobott F, Ciulli A.

J Biol Chem. 2015 Feb 13;290(7):4178-91. doi: 10.1074/jbc.M114.616664. Epub 2014 Dec 11.

42.

Global structural changes of an ion channel during its gating are followed by ion mobility mass spectrometry.

Konijnenberg A, Yilmaz D, Ingólfsson HI, Dimitrova A, Marrink SJ, Li Z, Vénien-Bryan C, Sobott F, Koçer A.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17170-5. doi: 10.1073/pnas.1413118111. Epub 2014 Nov 17.

43.

The intrinsically disordered domain of the antitoxin Phd chaperones the toxin Doc against irreversible inactivation and misfolding.

De Gieter S, Konijnenberg A, Talavera A, Butterer A, Haesaerts S, De Greve H, Sobott F, Loris R, Garcia-Pino A.

J Biol Chem. 2014 Dec 5;289(49):34013-23. doi: 10.1074/jbc.M114.572396. Epub 2014 Oct 16.

44.

Type III restriction endonucleases are heterotrimeric: comprising one helicase-nuclease subunit and a dimeric methyltransferase that binds only one specific DNA.

Butterer A, Pernstich C, Smith RM, Sobott F, Szczelkun MD, Tóth J.

Nucleic Acids Res. 2014 Apr;42(8):5139-50. doi: 10.1093/nar/gku122. Epub 2014 Feb 7.

45.

ETD allows for native surface mapping of a 150 kDa noncovalent complex on a commercial Q-TWIMS-TOF instrument.

Lermyte F, Konijnenberg A, Williams JP, Brown JM, Valkenborg D, Sobott F.

J Am Soc Mass Spectrom. 2014 Mar;25(3):343-50. doi: 10.1007/s13361-013-0798-3. Epub 2014 Jan 10.

PMID:
24408179
46.

LptA assembles into rod-like oligomers involving disorder-to-order transitions.

Santambrogio C, Sperandeo P, Villa R, Sobott F, Polissi A, Grandori R.

J Am Soc Mass Spectrom. 2013 Oct;24(10):1593-602. doi: 10.1007/s13361-013-0687-9. Epub 2013 Jul 30.

PMID:
23897621
47.

Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS.

Henderson CA, Vincent HA, Casamento A, Stone CM, Phillips JO, Cary PD, Sobott F, Gowers DM, Taylor JE, Callaghan AJ.

RNA. 2013 Aug;19(8):1089-104. doi: 10.1261/rna.034595.112. Epub 2013 Jun 26.

48.

Travelling wave ion mobility and negative ion fragmentation for the structural determination of N-linked glycans.

Harvey DJ, Scarff CA, Edgeworth M, Crispin M, Scanlan CN, Sobott F, Allman S, Baruah K, Pritchard L, Scrivens JH.

Electrophoresis. 2013 Aug;34(16):2368-78. doi: 10.1002/elps.201200669. Epub 2013 Jul 22.

PMID:
23712623
49.

Native ion mobility-mass spectrometry and related methods in structural biology.

Konijnenberg A, Butterer A, Sobott F.

Biochim Biophys Acta. 2013 Jun;1834(6):1239-56. doi: 10.1016/j.bbapap.2012.11.013. Epub 2012 Dec 14. Review.

PMID:
23246828
50.

Structural plasticity of histones H3-H4 facilitates their allosteric exchange between RbAp48 and ASF1.

Zhang W, Tyl M, Ward R, Sobott F, Maman J, Murthy AS, Watson AA, Fedorov O, Bowman A, Owen-Hughes T, El Mkami H, Murzina NV, Norman DG, Laue ED.

Nat Struct Mol Biol. 2013 Jan;20(1):29-35. doi: 10.1038/nsmb.2446. Epub 2012 Nov 25.

Supplemental Content

Loading ...
Support Center