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Post Genome-Wide Gene-Environment Interaction Study Using Random Survival Forest: Insulin Resistance, Lifestyle Factors, and Colorectal Cancer Risk.

Jung SY, Papp JC, Sobel EM, Zhang ZF.

Cancer Prev Res (Phila). 2019 Dec;12(12):877-890. doi: 10.1158/1940-6207.CAPR-19-0278. Epub 2019 Sep 25.


Post genome-wide gene-environment interaction study: The effect of genetically driven insulin resistance on breast cancer risk using Mendelian randomization.

Jung SY, Mancuso N, Papp J, Sobel E, Zhang ZF.

PLoS One. 2019 Jun 27;14(6):e0218917. doi: 10.1371/journal.pone.0218917. eCollection 2019.


Metformin Inhibits the Type 1 IFN Response in Human CD4+ T Cells.

Titov AA, Baker HV, Brusko TM, Sobel ES, Morel L.

J Immunol. 2019 Jul 15;203(2):338-348. doi: 10.4049/jimmunol.1801651. Epub 2019 Jun 3.


Breast Cancer Risk and Insulin Resistance: Post Genome-Wide Gene-Environment Interaction Study Using a Random Survival Forest.

Jung SY, Papp JC, Sobel EM, Yu H, Zhang ZF.

Cancer Res. 2019 May 15;79(10):2784-2794. doi: 10.1158/0008-5472.CAN-18-3688. Epub 2019 Apr 1.


OPENMENDEL: a cooperative programming project for statistical genetics.

Zhou H, Sinsheimer JS, Bates DM, Chu BB, German CA, Ji SS, Keys KL, Kim J, Ko S, Mosher GD, Papp JC, Sobel EM, Zhai J, Zhou JJ, Lange K.

Hum Genet. 2020 Jan;139(1):61-71. doi: 10.1007/s00439-019-02001-z. Epub 2019 Mar 26. Review.


Genome-Wide Meta-analysis of Gene-Environmental Interaction for Insulin Resistance Phenotypes and Breast Cancer Risk in Postmenopausal Women.

Jung SY, Mancuso N, Yu H, Papp J, Sobel E, Zhang ZF.

Cancer Prev Res (Phila). 2019 Jan;12(1):31-42. doi: 10.1158/1940-6207.CAPR-18-0180. Epub 2018 Oct 16.


The utility of trough mycophenolic acid levels for the management of lupus nephritis.

Pourafshar N, Karimi A, Wen X, Sobel E, Pourafshar S, Agrawal N, Segal E, Mohandas R, Segal MS.

Nephrol Dial Transplant. 2019 Jan 1;34(1):83-89. doi: 10.1093/ndt/gfy026.


Genetic Variants in Metabolic Signaling Pathways and Their Interaction with Lifestyle Factors on Breast Cancer Risk: A Random Survival Forest Analysis.

Jung SY, Papp JC, Sobel EM, Zhang ZF.

Cancer Prev Res (Phila). 2018 Jan;11(1):44-51. doi: 10.1158/1940-6207.CAPR-17-0143. Epub 2017 Oct 26.


Interaction of insulin-like growth factor-I and insulin resistance-related genetic variants with lifestyle factors on postmenopausal breast cancer risk.

Jung SY, Ho G, Rohan T, Strickler H, Bea J, Papp J, Sobel E, Zhang ZF, Crandall C.

Breast Cancer Res Treat. 2017 Jul;164(2):475-495. doi: 10.1007/s10549-017-4272-y. Epub 2017 May 6.


Human Birth Weight and Reproductive Immunology: Testing for Interactions between Maternal and Offspring KIR and HLA-C Genes.

Clark MM, Chazara O, Sobel EM, Gjessing HK, Magnus P, Moffett A, Sinsheimer JS.

Hum Hered. 2016;81(4):181-193. doi: 10.1159/000456033. Epub 2017 Feb 18.


Genome-wide QTL and eQTL analyses using Mendel.

Zhou H, Zhou J, Hu T, Sobel EM, Lange K.

BMC Proc. 2016 Oct 18;10(Suppl 7):239-244. eCollection 2016.


Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data.

Zhou H, Blangero J, Dyer TD, Chan KK, Lange K, Sobel EM.

Genet Epidemiol. 2017 Apr;41(3):174-186. doi: 10.1002/gepi.21988. Epub 2016 Dec 12.


A case of isolated renal involvement of polyarteritis nodosa successfully treated with steroid monotherapy.

Pourafshar N, Sobel E, Segal M.

BMJ Case Rep. 2016 Jul 20;2016. pii: bcr2016215702. doi: 10.1136/bcr-2016-215702.


Obesity and associated lifestyles modify the effect of glucose metabolism-related genetic variants on impaired glucose homeostasis among postmenopausal women.

Jung SY, Sobel EM, Papp JC, Crandall CJ, Fu AN, Zhang ZF.

Genet Epidemiol. 2016 Sep;40(6):520-30. doi: 10.1002/gepi.21991. Epub 2016 Jul 5.


A Novel Mechanism for Generating the Interferon Signature in Lupus: Opsonization of Dead Cells by Complement and IgM.

Zhuang H, Han S, Li Y, Kienhöfer D, Lee P, Shumyak S, Meyerholz R, Rosadzinski K, Rosner D, Chan A, Xu Y, Segal M, Sobel E, Yang LJ, Hoffmann MH, Reeves WH.

Arthritis Rheumatol. 2016 Dec;68(12):2917-2928. doi: 10.1002/art.39781.


The Quantitative-MFG Test: A Linear Mixed Effect Model to Detect Maternal-Offspring Gene Interactions.

Clark MM, Blangero J, Dyer TD, Sobel EM, Sinsheimer JS.

Ann Hum Genet. 2016 Jan;80(1):63-80. doi: 10.1111/ahg.12137. Epub 2015 Nov 15.


Rotation of large asymmetrical absorbing objects by Laguerre-Gauss beams.

Herne CM, Capuzzi KM, Sobel E, Kropas RT.

Opt Lett. 2015 Sep 1;40(17):4026-9. doi: 10.1364/OL.40.004026.


Occupant and Crash Characteristics of Elderly Subjects With Thoracic and Lumbar Spine Injuries After Motor Vehicle Collisions.

Rao RD, Sobel EH, Berry CA, Yoganandan N.

Spine (Phila Pa 1976). 2016 Jan;41(1):32-8. doi: 10.1097/BRS.0000000000001079.


Genome-wide ultraconserved elements exhibit higher phylogenetic informativeness than traditional gene markers in percomorph fishes.

Gilbert PS, Chang J, Pan C, Sobel EM, Sinsheimer JS, Faircloth BC, Alfaro ME.

Mol Phylogenet Evol. 2015 Nov;92:140-6. doi: 10.1016/j.ympev.2015.05.027. Epub 2015 Jun 12.


Normalization of CD4+ T cell metabolism reverses lupus.

Yin Y, Choi SC, Xu Z, Perry DJ, Seay H, Croker BP, Sobel ES, Brusko TM, Morel L.

Sci Transl Med. 2015 Feb 11;7(274):274ra18. doi: 10.1126/scitranslmed.aaa0835.


Serpin treatment suppresses inflammatory vascular lesions in temporal artery implants (TAI) from patients with giant cell arteritis.

Chen H, Zheng D, Ambadapadi S, Davids J, Ryden S, Samy H, Bartee M, Sobel E, Dai E, Liu L, Macaulay C, Yachnis A, Weyand C, Thoburn R, Lucas A.

PLoS One. 2015 Feb 6;10(2):e0115482. doi: 10.1371/journal.pone.0115482. eCollection 2015.


Fast genome-wide pedigree quantitative trait loci analysis using MENDEL.

Zhou H, Zhou J, Sobel EM, Lange K.

BMC Proc. 2014 Jun 17;8(Suppl 1):S93. doi: 10.1186/1753-6561-8-S1-S93. eCollection 2014.


Shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities.

Chan KH, Huang YT, Meng Q, Wu C, Reiner A, Sobel EM, Tinker L, Lusis AJ, Yang X, Liu S.

Circ Cardiovasc Genet. 2014 Dec;7(6):911-9. doi: 10.1161/CIRCGENETICS.114.000676. Epub 2014 Nov 4.


Osteoarthritis and psoriatic arthritis: findings in three-dimensional biophotonics imaging.

Yuan Z, Ieong FH, Jiang H, Sobel ES.

Biomed Mater Eng. 2014;24(6):3063-71. doi: 10.3233/BME-141128.


Ocular Tonometry and Sporadic Creutzfeldt - Jakob Disease (sCJD): A Confirmatory Case-Control Study.

Davanipour Z, Sobel E, Ziogas A, Smoak C, Bohr T, Doram K, Liwnicz B.

Br J Med Med Res. 2014 Apr 30;4(12):2322-2333.


Dietary Risk Factors for Sporadic Creutzfeldt-Jakob Disease: A Confirmatory Case-Control Study.

Davanipour Z, Sobel E, Ziogas A, Smoak C, Bohr T, Doram K, Liwnicz B.

Br J Med Med Res. 2014 Apr 21;4(12):2388-2417.


Increased IFN-α-producing plasmacytoid dendritic cells (pDCs) in human Th1-mediated type 1 diabetes: pDCs augment Th1 responses through IFN-α production.

Xia CQ, Peng R, Chernatynskaya AV, Yuan L, Carter C, Valentine J, Sobel E, Atkinson MA, Clare-Salzler MJ.

J Immunol. 2014 Aug 1;193(3):1024-34. doi: 10.4049/jimmunol.1303230. Epub 2014 Jun 27.


Next Generation Statistical Genetics: Modeling, Penalization, and Optimization in High-Dimensional Data.

Lange K, Papp JC, Sinsheimer JS, Sobel EM.

Annu Rev Stat Appl. 2014 Jan 1;1(1):279-300.


Severe Cognitive Dysfunction and Occupational Extremely Low Frequency Magnetic Field Exposure among Elderly Mexican Americans.

Davanipour Z, Tseng CC, Lee PJ, Markides KS, Sobel E.

Br J Med Med Res. 2014 Apr 16;4(8):1641-1662.


Reduced levels of CCL2 and CXCL10 in systemic lupus erythematosus patients under treatment with prednisone, mycophenolate mofetil, or hydroxychloroquine, except in a high STAT1 subset.

Dominguez-Gutierrez PR, Ceribelli A, Satoh M, Sobel ES, Reeves WH, Chan EK.

Arthritis Res Ther. 2014 Jan 24;16(1):R23. doi: 10.1186/ar4451.


Positive correlation of STAT1 and miR-146a with anemia in patients with systemic lupus erythematosus.

Dominguez-Gutierrez PR, Ceribelli A, Satoh M, Sobel ES, Reeves WH, Chan EK.

J Clin Immunol. 2014 Feb;34(2):171-80. doi: 10.1007/s10875-013-9973-3. Epub 2013 Dec 1.


The systems genetics resource: a web application to mine global data for complex disease traits.

van Nas A, Pan C, Ingram-Drake LA, Ghazalpour A, Drake TA, Sobel EM, Papp JC, Lusis AJ.

Front Genet. 2013 May 20;4:84. doi: 10.3389/fgene.2013.00084. eCollection 2013.


Mendel: the Swiss army knife of genetic analysis programs.

Lange K, Papp JC, Sinsheimer JS, Sripracha R, Zhou H, Sobel EM.

Bioinformatics. 2013 Jun 15;29(12):1568-70. doi: 10.1093/bioinformatics/btt187. Epub 2013 Apr 22.


Maintenance of anti-Sm/RNP autoantibody production by plasma cells residing in ectopic lymphoid tissue and bone marrow memory B cells.

Weinstein JS, Delano MJ, Xu Y, Kelly-Scumpia KM, Nacionales DC, Li Y, Lee PY, Scumpia PO, Yang L, Sobel E, Moldawer LL, Reeves WH.

J Immunol. 2013 Apr 15;190(8):3916-27. doi: 10.4049/jimmunol.1201880. Epub 2013 Mar 18.


Common genetic variants in peroxisome proliferator-activated receptor-γ (PPARG) and type 2 diabetes risk among Women's Health Initiative postmenopausal women.

Chan KH, Niu T, Ma Y, You NC, Song Y, Sobel EM, Hsu YH, Balasubramanian R, Qiao Y, Tinker L, Liu S.

J Clin Endocrinol Metab. 2013 Mar;98(3):E600-4. doi: 10.1210/jc.2012-3644. Epub 2013 Feb 5.


Application of new method for evaluating performance of fracture risk tool.

Sobel EM, Ettinger B, Lo JC, Pressman AR.

Am J Manag Care. 2012 Oct 1;18(10):e398. No abstract available.


Adult asthma and risk of coronary heart disease, cerebrovascular disease, and heart failure: a prospective study of 2 matched cohorts.

Iribarren C, Tolstykh IV, Miller MK, Sobel E, Eisner MD.

Am J Epidemiol. 2012 Dec 1;176(11):1014-24. doi: 10.1093/aje/kws181. Epub 2012 Nov 8.


Mendel-GPU: haplotyping and genotype imputation on graphics processing units.

Chen GK, Wang K, Stram AH, Sobel EM, Lange K.

Bioinformatics. 2012 Nov 15;28(22):2979-80. doi: 10.1093/bioinformatics/bts536. Epub 2012 Sep 5.


Autoantibodies to transcription intermediary factor TIF1β associated with dermatomyositis.

Satoh M, Chan JY, Ross SJ, Li Y, Yamasaki Y, Yamada H, Vazquez-del Mercado M, Petri MH, Jara LJ, Saavedra MA, Cruz-Reyes C, Sobel ES, Reeves WH, Ceribelli A, Chan EK.

Arthritis Res Ther. 2012 Apr 17;14(2):R79. doi: 10.1186/ar3802.


Shared loci for migraine and epilepsy on chromosomes 14q12-q23 and 12q24.2-q24.3.

Polvi A, Siren A, Kallela M, Rantala H, Artto V, Sobel EM, Palotie A, Lehesjoki AE, Wessman M.

Neurology. 2012 Jan 17;78(3):202-9. doi: 10.1212/WNL.0b013e31823fcd87. Epub 2012 Jan 4.


Pre-B cell leukemia homeobox 1 is associated with lupus susceptibility in mice and humans.

Cuda CM, Li S, Liang S, Yin Y, Potula HH, Xu Z, Sengupta M, Chen Y, Butfiloski E, Baker H, Chang LJ, Dozmorov I, Sobel ES, Morel L.

J Immunol. 2012 Jan 15;188(2):604-14. doi: 10.4049/jimmunol.1002362. Epub 2011 Dec 16.


Quantitative trait Loci association mapping by imputation of strain origins in multifounder crosses.

Zhou JJ, Ghazalpour A, Sobel EM, Sinsheimer JS, Lange K.

Genetics. 2012 Feb;190(2):459-73. doi: 10.1534/genetics.111.135095. Epub 2011 Dec 5.


Coexistence of anti-RNA polymerase III and anti-U1RNP antibodies in patients with systemic lupus erythematosus: two cases without features of scleroderma.

Satoh M, Vazquez-Del Mercado M, Krzyszczak ME, Li Y, Ceribelli A, Burlingame RW, Webb TT, Sobel ES, Reeves WH, Chan EK.

Lupus. 2012 Jan;21(1):68-74. doi: 10.1177/0961203311422712. Epub 2011 Oct 24.


Detection of intergenerational genetic effects with application to HLA-B matching as a risk factor for schizophrenia.

Childs EJ, Sobel EM, Palmer CG, Sinsheimer JS.

Hum Hered. 2011;72(3):161-72. doi: 10.1159/000332051. Epub 2011 Oct 15.


Unifying ideas for non-parametric linkage analysis.

Day-Williams AG, Blangero J, Dyer TD, Lange K, Sobel EM.

Hum Hered. 2011;71(4):267-80. doi: 10.1159/000323752. Epub 2011 Aug 3.


Pathogenic role of B cells in the development of diffuse alveolar hemorrhage induced by pristane.

Barker TT, Lee PY, Kelly-Scumpia KM, Weinstein JS, Nacionales DC, Kumagai Y, Akira S, Croker BP, Sobel ES, Reeves WH, Satoh M.

Lab Invest. 2011 Oct;91(10):1540-50. doi: 10.1038/labinvest.2011.108. Epub 2011 Aug 1.


Atypical clinical presentation of a subset of patients with anti-RNA polymerase III--non-scleroderma cases associated with dominant RNA polymerase I reactivity and nucleolar staining.

Ceribelli A, Krzyszczak ME, Li Y, Ross SJ, Chan JY, Chan EK, Burlingame RW, Webb TT, Bubb MR, Sobel ES, Reeves WH, Satoh M.

Arthritis Res Ther. 2011 Jul 22;13(4):R119. doi: 10.1186/ar3422.

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