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Items: 1 to 50 of 108

1.

Natural history of 39 patients with Achondroplasia.

Ceroni JRM, Soares DCQ, Testai LC, Kawahira RSH, Yamamoto GL, Sugayama SMM, Oliveira LAN, Bertola DR, Kim CA.

Clinics (Sao Paulo). 2018 Jul 2;73:e324. doi: 10.6061/clinics/2018/e324.

2.

Synthesis of cholesterol-based neoglycoconjugates and their use in the preparation of liposomes for active liver targeting.

E Silva ATM, Maia ALC, de Oliveira Silva J, de Barros ALB, Soares DCF, de Magalhães MTQ, José Alves R, Ramaldes GA.

Carbohydr Res. 2018 Jun 18;465:52-57. doi: 10.1016/j.carres.2018.06.008. [Epub ahead of print]

PMID:
29944996
3.

HIV-1 Uncoating and Reverse Transcription Require eEF1A Binding to Surface-Exposed Acidic Residues of the Reverse Transcriptase Thumb Domain.

Rawle DJ, Li D, Swedberg JE, Wang L, Soares DC, Harrich D.

MBio. 2018 Mar 27;9(2). pii: e00316-18. doi: 10.1128/mBio.00316-18.

4.

Triterpenes from leaves of Cheiloclinium cognatum and their in vivo antiangiogenic activity.

Pereira RCG, Soares DCF, Oliveira DCP, de Sousa GF, Vieira-Filho SA, Mercadante-Simões MO, Lula I, Silva-Cunha A, Duarte LP.

Magn Reson Chem. 2018 May;56(5):360-366. doi: 10.1002/mrc.4716. Epub 2018 Feb 20. No abstract available.

PMID:
29388257
5.

Characterization of a novel RP2-OSTF1 interaction and its implication for actin remodelling.

Lyraki R, Lokaj M, Soares DC, Little A, Vermeren M, Marsh JA, Wittinghofer A, Hurd T.

J Cell Sci. 2018 Feb 20;131(4). pii: jcs211748. doi: 10.1242/jcs.211748.

PMID:
29361551
6.

The in vitro antileishmanial activity of essential oil from Aloysia gratissima and guaiol, its major sesquiterpene against Leishmania amazonensis.

Garcia MCF, Soares DC, Santana RC, Saraiva EM, Siani AC, Ramos MFS, Danelli MDGM, Souto-Padron TC, Pinto-da-Silva LH.

Parasitology. 2018 Jan 21:1-9. doi: 10.1017/S0031182017002335. [Epub ahead of print]

PMID:
29352826
7.

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.

Johnston CJC, Smyth DJ, Kodali RB, White MPJ, Harcus Y, Filbey KJ, Hewitson JP, Hinck CS, Ivens A, Kemter AM, Kildemoes AO, Le Bihan T, Soares DC, Anderton SM, Brenn T, Wigmore SJ, Woodcock HV, Chambers RC, Hinck AP, McSorley HJ, Maizels RM.

Nat Commun. 2017 Nov 23;8(1):1741. doi: 10.1038/s41467-017-01886-6.

8.

HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.

Osbourn M, Soares DC, Vacca F, Cohen ES, Scott IC, Gregory WF, Smyth DJ, Toivakka M, Kemter AM, le Bihan T, Wear M, Hoving D, Filbey KJ, Hewitson JP, Henderson H, Gonzàlez-Cìscar A, Errington C, Vermeren S, Astier AL, Wallace WA, Schwarze J, Ivens AC, Maizels RM, McSorley HJ.

Immunity. 2017 Oct 17;47(4):739-751.e5. doi: 10.1016/j.immuni.2017.09.015.

9.

Treatment with pentylenetetrazole (PTZ) and 4-aminopyridine (4-AP) differently affects survival, locomotor activity, and biochemical markers in Drosophila melanogaster.

Soares DCS, Portela JLR, Roos DH, Rodrigues NR, Gomes KK, Macedo GE, Posser T, Franco JL, Hassan W, Puntel RL.

Mol Cell Biochem. 2018 May;442(1-2):129-142. doi: 10.1007/s11010-017-3198-3. Epub 2017 Oct 10.

PMID:
28994023
10.

Antileishmanial Thioureas: Synthesis, Biological Activity and in Silico Evaluations of New Promising Derivatives.

Viana GM, Soares DC, Santana MV, do Amaral LH, Meireles PW, Nunes RP, da Silva LCRP, Aguiar LCS, Rodrigues CR, de Sousa VP, Castro HC, Abreu PA, Sathler PC, Saraiva EM, Cabral LM.

Chem Pharm Bull (Tokyo). 2017;65(10):911-919. doi: 10.1248/cpb.c17-00293.

11.

Novel pathogenic mutations in C1QTNF5 support a dominant negative disease mechanism in late-onset retinal degeneration.

Stanton CM, Borooah S, Drake C, Marsh JA, Campbell S, Lennon A, Soares DC, Vallabh NA, Sahni J, Cideciyan AV, Dhillon B, Vitart V, Jacobson SG, Wright AF, Hayward C.

Sci Rep. 2017 Sep 22;7(1):12147. doi: 10.1038/s41598-017-11898-3.

12.

The role of radionuclide probes for monitoring anti-tumor drugs efficacy: A brief review.

Fernandes RS, de Aguiar Ferreira C, Soares DCF, Maffione AM, Townsend DM, Rubello D, de Barros ALB.

Biomed Pharmacother. 2017 Nov;95:469-476. doi: 10.1016/j.biopha.2017.08.079. Epub 2017 Sep 12. Review.

PMID:
28865367
13.

Evaluation of the Glittre-ADL test as an instrument for classifying functional capacity of individuals with cardiovascular diseases.

Fernandes-Andrade AA, Britto RR, Soares DCM, Velloso M, Pereira DAG.

Braz J Phys Ther. 2017 Sep - Oct;21(5):321-328. doi: 10.1016/j.bjpt.2017.06.001. Epub 2017 Jul 3.

14.

Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia.

Teng S, Thomson PA, McCarthy S, Kramer M, Muller S, Lihm J, Morris S, Soares DC, Hennah W, Harris S, Camargo LM, Malkov V, McIntosh AM, Millar JK, Blackwood DH, Evans KL, Deary IJ, Porteous DJ, McCombie WR.

Mol Psychiatry. 2018 May;23(5):1270-1277. doi: 10.1038/mp.2017.115. Epub 2017 Jun 20.

15.

SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs.

Nozawa RS, Boteva L, Soares DC, Naughton C, Dun AR, Buckle A, Ramsahoye B, Bruton PC, Saleeb RS, Arnedo M, Hill B, Duncan RR, Maciver SK, Gilbert N.

Cell. 2017 Jun 15;169(7):1214-1227.e18. doi: 10.1016/j.cell.2017.05.029.

16.

Antiangiogenic activity of PLGA-Lupeol implants for potential intravitreal applications.

Soares DCF, de Paula Oliveira DC, Barcelos LS, Barbosa AS, Vieira LC, Townsend DM, Rubello D, de Barros ALB, Duarte LP, Silva-Cunha A.

Biomed Pharmacother. 2017 Aug;92:394-402. doi: 10.1016/j.biopha.2017.05.093. Epub 2017 May 27.

PMID:
28558353
17.

A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma.

Rainger J, Williamson KA, Soares DC, Truch J, Kurian D, Gillessen-Kaesbach G, Seawright A, Prendergast J, Halachev M, Wheeler A, McTeir L, Gill AC, van Heyningen V, Davey MG; UK10K, FitzPatrick DR.

Hum Mutat. 2017 Aug;38(8):942-946. doi: 10.1002/humu.23246. Epub 2017 Jun 6.

18.

Functional disability indicators and associated factors in the elderly: a population-based study in Bagé, Rio Grande do Sul, Brazil.

Nunes JD, Saes MO, Nunes BP, Siqueira FCV, Soares DC, Fassa MEG, Thumé E, Facchini LA.

Epidemiol Serv Saude. 2017 Apr-Jun;26(2):295-304. doi: 10.5123/S1679-49742017000200007. Portuguese, English.

19.

PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.

Hall EA, Nahorski MS, Murray LM, Shaheen R, Perkins E, Dissanayake KN, Kristaryanto Y, Jones RA, Vogt J, Rivagorda M, Handley MT, Mali GR, Quidwai T, Soares DC, Keighren MA, McKie L, Mort RL, Gammoh N, Garcia-Munoz A, Davey T, Vermeren M, Walsh D, Budd P, Aligianis IA, Faqeih E, Quigley AJ, Jackson IJ, Kulathu Y, Jackson M, Ribchester RR, von Kriegsheim A, Alkuraya FS, Woods CG, Maher ER, Mill P.

Am J Hum Genet. 2017 May 4;100(5):706-724. doi: 10.1016/j.ajhg.2017.03.008. Epub 2017 Apr 13.

20.

Ablation of EYS in zebrafish causes mislocalisation of outer segment proteins, F-actin disruption and cone-rod dystrophy.

Lu Z, Hu X, Liu F, Soares DC, Liu X, Yu S, Gao M, Han S, Qin Y, Li C, Jiang T, Luo D, Guo AY, Tang Z, Liu M.

Sci Rep. 2017 Apr 5;7:46098. doi: 10.1038/srep46098.

21.

Functionalized single-walled carbon nanotubes: cellular uptake, biodistribution and applications in drug delivery.

Li Z, de Barros ALB, Soares DCF, Moss SN, Alisaraie L.

Int J Pharm. 2017 May 30;524(1-2):41-54. doi: 10.1016/j.ijpharm.2017.03.017. Epub 2017 Mar 11. Review.

PMID:
28300630
22.

A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations.

Yerabham ASK, Mas PJ, Decker C, Soares DC, Weiergräber OH, Nagel-Steger L, Willbold D, Hart DJ, Bradshaw NJ, Korth C.

J Biol Chem. 2017 Apr 21;292(16):6468-6477. doi: 10.1074/jbc.M116.773903. Epub 2017 Mar 1.

23.

Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish.

Liu F, Qin Y, Yu S, Soares DC, Yang L, Weng J, Li C, Gao M, Lu Z, Hu X, Liu X, Jiang T, Liu JY, Shu X, Tang Z, Liu M.

J Biol Chem. 2017 Apr 14;292(15):6225-6239. doi: 10.1074/jbc.M116.760314. Epub 2017 Feb 16.

24.

Leishmanicidal activity of the alkaloid-rich fraction from Guatteria latifolia.

Ferreira C, Passos CL, Soares DC, Costa KP, Rezende MJ, Lobão AQ, Pinto AC, Hamerski L, Saraiva EM.

Exp Parasitol. 2017 Jan;172:51-60. doi: 10.1016/j.exppara.2016.12.014. Epub 2016 Dec 21.

PMID:
28011169
25.

Herpetiform keratitis and palmoplantar hyperkeratosis: warning signs for Richner-Hanhart syndrome.

Soares DC, Stroparo MN, Lian YC, Takakura CY, Wolf S, Betz R, Kim CA.

J Inherit Metab Dis. 2017 May;40(3):461-462. doi: 10.1007/s10545-016-9996-z. Epub 2016 Nov 10.

PMID:
27832414
26.

Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability.

Woodward J, Taylor GC, Soares DC, Boyle S, Sie D, Read D, Chathoth K, Vukovic M, Tarrats N, Jamieson D, Campbell KJ, Blyth K, Acosta JC, Ylstra B, Arends MJ, Kranc KR, Jackson AP, Bickmore WA, Wood AJ.

Genes Dev. 2016 Oct 1;30(19):2173-2186. Epub 2016 Oct 13.

27.

The Brown Alga Stypopodium zonale (Dictyotaceae): A Potential Source of Anti-Leishmania Drugs.

Soares DC, Szlachta MM, Teixeira VL, Soares AR, Saraiva EM.

Mar Drugs. 2016 Sep 8;14(9). pii: E163. doi: 10.3390/md14090163.

28.

Liposomes Containing Gadodiamide: Preparation, Physicochemical Characterization, and In Vitro Cytotoxic Evaluation.

Maia ALC, Fernandes C, de Oliveira CNP, Teixeira CS, Oliveira MS, Soares DCF, Ramaldes GA.

Curr Drug Deliv. 2017;14(4):566-574. doi: 10.2174/1567201813666160907095404.

PMID:
27605018
29.

Novel de novo EEF1A2 missense mutations causing epilepsy and intellectual disability.

Lam WW, Millichap JJ, Soares DC, Chin R, McLellan A, FitzPatrick DR, Elmslie F, Lees MM, Schaefer GB; DDD study, Abbott CM.

Mol Genet Genomic Med. 2016 Apr 3;4(4):465-74. doi: 10.1002/mgg3.219. eCollection 2016 Jul.

30.

Clinical description of 41 Brazilian patients with oculo-auriculo-vertebral dysplasia.

Pegler JR, Soares DC, Quaio CR, Fernandes N, Oliveira LA, Honjo RS, Bertola DR, Kim CA.

Rev Assoc Med Bras (1992). 2016 May-Jun;62(3):202-6. doi: 10.1590/1806-9282.62.03.202.

31.

Hydroxyapatite nanoparticles: preparation, characterization, and evaluation of their potential use in bone targeting: an animal study.

Maia AL, Cavalcante CH, Souza MG, Ferreira Cde A, Rubello D, Chondrogiannis S, Cardoso VN, Ramaldes GA, Barros AL, Soares DC.

Nucl Med Commun. 2016 Jul;37(7):775-82. doi: 10.1097/MNM.0000000000000510.

PMID:
27076207
32.

Short Communication Impact of early enzyme-replacement therapy for mucopolysaccharidosis VI: results of a long-term follow-up of Brazilian siblings.

Franco JF, Soares DC, Torres LC, Leal GN, Cunha MT, Honjo RS, Bertola DR, Kim CA.

Genet Mol Res. 2016 Feb 22;15(1). doi: 10.4238/gmr.15017850.

33.

Oleanolic acid (OA) as an antileishmanial agent: Biological evaluation and in silico mechanistic insights.

Melo TS, Gattass CR, Soares DC, Cunha MR, Ferreira C, Tavares MT, Saraiva E, Parise-Filho R, Braden H, Delorenzi JC.

Parasitol Int. 2016 Jun;65(3):227-37. doi: 10.1016/j.parint.2016.01.001. Epub 2016 Jan 6.

PMID:
26772973
34.

CD4+CD25 high Foxp3+ Treg deficiency in a Brazilian patient with Gaucher disease and lupus nephritis.

Matta MC, Soares DC, Kerstenetzky MS, Freitas AC, Kim CA, Torres LC.

Hum Immunol. 2016 Feb;77(2):196-200. doi: 10.1016/j.humimm.2015.11.018. Epub 2015 Dec 7.

PMID:
26673565
35.

Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target.

Li D, Wei T, Rawle DJ, Qin F, Wang R, Soares DC, Jin H, Sivakumaran H, Lin MH, Spann K, Abbott CM, Harrich D.

PLoS Pathog. 2015 Dec 1;11(12):e1005289. doi: 10.1371/journal.ppat.1005289. eCollection 2015 Dec.

36.

HIV-1 Tat protein enhances the intracellular growth of Leishmania amazonensis via the ds-RNA induced protein PKR.

Vivarini Áde C, Pereira Rde M, Barreto-de-Souza V, Temerozo JR, Soares DC, Saraiva EM, Saliba AM, Bou-Habib DC, Lopes UG.

Sci Rep. 2015 Nov 26;5:16777. doi: 10.1038/srep16777.

37.

Leishmanicidal Effect of Synthetic trans-Resveratrol Analogs.

Passos CL, Ferreira C, Soares DC, Saraiva EM.

PLoS One. 2015 Oct 30;10(10):e0141778. doi: 10.1371/journal.pone.0141778. eCollection 2015.

38.

Energy requirements for growth in male and female Saanen goats.

Almeida AK, Resende KT, St-Pierre N, Silva SP, Soares DC, Fernandes MH, Souza AP, Silva NC, Lima AR, Teixeira IA.

J Anim Sci. 2015 Aug;93(8):3932-40. doi: 10.2527/jas.2014-8632.

PMID:
26440173
39.

Evolutionary Characterization of the Retinitis Pigmentosa GTPase Regulator Gene.

Raghupathy RK, Gautier P, Soares DC, Wright AF, Shu X.

Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6255-64. doi: 10.1167/iovs.15-17726.

40.

RPGR: Its role in photoreceptor physiology, human disease, and future therapies.

Megaw RD, Soares DC, Wright AF.

Exp Eye Res. 2015 Sep;138:32-41. doi: 10.1016/j.exer.2015.06.007. Epub 2015 Jun 17. Review.

41.

Targeted sequencing of the Paget's disease associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone.

Vallet M, Soares DC, Wani S, Sophocleous A, Warner J, Salter DM, Ralston SH, Albagha OM.

Hum Mol Genet. 2015 Jun 1;24(11):3286-95. doi: 10.1093/hmg/ddv068. Epub 2015 Feb 20.

42.

IL-27 enhances Leishmania amazonensis infection via ds-RNA dependent kinase (PKR) and IL-10 signaling.

Barreto-de-Souza V, Ferreira PL, Vivarini Ade C, Calegari-Silva T, Soares DC, Regis EG, Pereira RM, Silva AM, Saraiva EM, Lopes UG, Bou-Habib DC.

Immunobiology. 2015 Apr;220(4):437-44. doi: 10.1016/j.imbio.2014.11.006. Epub 2014 Nov 15.

PMID:
25466588
43.

Lipoid proteinosis: rare case confirmed by ECM1 mutation detection.

Almeida TF, Soares DC, Quaio CR, Honjo RS, Bertola DR, McGrath JA, Kim CA.

Int J Pediatr Otorhinolaryngol. 2014 Dec;78(12):2314-5. doi: 10.1016/j.ijporl.2014.09.025. Epub 2014 Oct 2. No abstract available.

PMID:
25441608
44.

Atypical femoral fracture in osteoporosis pseudoglioma syndrome associated with two novel compound heterozygous mutations in LRP5.

Alonso N, Soares DC, V McCloskey E, Summers GD, Ralston SH, Gregson CL.

J Bone Miner Res. 2015 Apr;30(4):615-20. doi: 10.1002/jbmr.2403.

45.

Resveratrol is active against Leishmania amazonensis: in vitro effect of its association with Amphotericin B.

Ferreira C, Soares DC, Nascimento MT, Pinto-da-Silva LH, Sarzedas CG, Tinoco LW, Saraiva EM.

Antimicrob Agents Chemother. 2014 Oct;58(10):6197-208. doi: 10.1128/AAC.00093-14. Epub 2014 Aug 11.

46.

NK and B cell deficiency in a MPS type II family with novel mutation in the IDS gene.

Torres LC, Soares DC, Kulikowski LD, Franco JF, Kim CA.

Clin Immunol. 2014 Oct;154(2):100-4. doi: 10.1016/j.clim.2014.07.001. Epub 2014 Jul 16.

PMID:
25038527
47.

Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.

Rainger J, Pehlivan D, Johansson S, Bengani H, Sanchez-Pulido L, Williamson KA, Ture M, Barker H, Rosendahl K, Spranger J, Horn D, Meynert A, Floyd JA, Prescott T, Anderson CA, Rainger JK, Karaca E, Gonzaga-Jauregui C, Jhangiani S, Muzny DM, Seawright A, Soares DC, Kharbanda M, Murday V, Finch A; UK10K; Baylor-Hopkins Center for Mendelian Genomics, Gibbs RA, van Heyningen V, Taylor MS, Yakut T, Knappskog PM, Hurles ME, Ponting CP, Lupski JR, Houge G, FitzPatrick DR.

Am J Hum Genet. 2014 Jun 5;94(6):915-23. doi: 10.1016/j.ajhg.2014.05.005.

48.

DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan.

Porteous DJ, Thomson PA, Millar JK, Evans KL, Hennah W, Soares DC, McCarthy S, McCombie WR, Clapcote SJ, Korth C, Brandon NJ, Sawa A, Kamiya A, Roder JC, Lawrie SM, McIntosh AM, St Clair D, Blackwood DH.

Mol Psychiatry. 2014 Feb;19(2):141-3. doi: 10.1038/mp.2013.160. No abstract available.

50.

Boron nitride nanotubes coated with organic hydrophilic agents: stability and cytocompatibility studies.

Ferreira TH, Soares DC, Moreira LM, da Silva PR, dos Santos RG, de Sousa EM.

Mater Sci Eng C Mater Biol Appl. 2013 Dec 1;33(8):4616-23. doi: 10.1016/j.msec.2013.07.024. Epub 2013 Jul 25.

PMID:
24094168

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