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Items: 1 to 50 of 205

1.

Emerging approaches in predictive toxicology.

Zhang L, McHale CM, Greene N, Snyder RD, Rich IN, Aardema MJ, Roy S, Pfuhler S, Venkatactahalam S.

Environ Mol Mutagen. 2014 Dec;55(9):679-88. doi: 10.1002/em.21885. Epub 2014 Jul 9.

2.

Evidence for the contribution of non-covalent steroid interactions between DNA and topoisomerase in the genotoxicity of steroids.

Snyder RD, Holt PA, Maguire JM, Trent JO.

Drug Chem Toxicol. 2015 Apr;38(2):212-9. doi: 10.3109/01480545.2014.928725. Epub 2014 Jun 30.

PMID:
24975547
3.

Patterns of Recurrence and outcome according to breast cancer subtypes in lymph node-negative disease: results from international breast cancer study group trials VIII and IX.

Metzger-Filho O, Sun Z, Viale G, Price KN, Crivellari D, Snyder RD, Gelber RD, Castiglione-Gertsch M, Coates AS, Goldhirsch A, Cardoso F.

J Clin Oncol. 2013 Sep 1;31(25):3083-90. doi: 10.1200/JCO.2012.46.1574. Epub 2013 Jul 29.

4.

Prediction of noncovalent Drug/DNA interaction using computational docking models: studies with over 1350 launched drugs.

Snyder RD, Holt PA, Maguire JM, Trent JO.

Environ Mol Mutagen. 2013 Oct;54(8):668-81. doi: 10.1002/em.21796. Epub 2013 Jul 26.

PMID:
23893771
5.

Bacterial mutagenicity screening in the pharmaceutical industry.

Escobar PA, Kemper RA, Tarca J, Nicolette J, Kenyon M, Glowienke S, Sawant SG, Christensen J, Johnson TE, McKnight C, Ward G, Galloway SM, Custer L, Gocke E, O'Donovan MR, Braun K, Snyder RD, Mahadevan B.

Mutat Res. 2013 Apr-Jun;752(2):99-118. doi: 10.1016/j.mrrev.2012.12.002. Epub 2012 Dec 20. Review. Erratum in: Mutat Res. 2013 Oct-Dec;753(2):155.

PMID:
23262374
6.

A retrospective cohort study of metastatic colorectal cancer patients treated with oxaliplatin-based chemotherapy, with an exploratory analysis of changing serum carcinoembryonic antigen levels.

Ng SL, Burns WI, Snyder RD, Newnham GM, McLachlan SA, Liew D, Dowling AJ.

Asia Pac J Clin Oncol. 2012 Jun;8(2):172-9. doi: 10.1111/j.1743-7563.2011.01486.x. Epub 2012 Jan 12.

PMID:
22524576
7.

Circulating markers of vascular injury and angiogenesis in antineutrophil cytoplasmic antibody-associated vasculitis.

Monach PA, Tomasson G, Specks U, Stone JH, Cuthbertson D, Krischer J, Ding L, Fervenza FC, Fessler BJ, Hoffman GS, Ikle D, Kallenberg CG, Langford CA, Mueller M, Seo P, St Clair EW, Spiera R, Tchao N, Ytterberg SR, Gu YZ, Snyder RD, Merkel PA.

Arthritis Rheum. 2011 Dec;63(12):3988-97. doi: 10.1002/art.30615.

8.

Genetic toxicology in the 21st century: reflections and future directions.

Mahadevan B, Snyder RD, Waters MD, Benz RD, Kemper RA, Tice RR, Richard AM.

Environ Mol Mutagen. 2011 Jun;52(5):339-54. doi: 10.1002/em.20653. Epub 2011 Apr 28. Review.

9.

Effects of the histamine H1 antagonist chlorcyclizine on rat fetal palate development.

Enright BP, Gu YZ, Snyder RD, Dugyala RR, Obert LA, Treinen KA, McIntyre BS, Veneziale RW.

Birth Defects Res B Dev Reprod Toxicol. 2010 Dec;89(6):474-84. doi: 10.1002/bdrb.20261.

PMID:
21058326
10.

Possible structural and functional determinants contributing to the clastogenicity of pharmaceuticals.

Snyder RD.

Environ Mol Mutagen. 2010 Oct-Dec;51(8-9):800-14. doi: 10.1002/em.20626. Review.

PMID:
20872827
11.

Early events in vascular injury in the rat induced by the phosphodiesterase IV inhibitor SCH 351591.

Weaver JL, Zhang J, Knapton A, Miller T, Espandiari P, Smith R, Gu YZ, Snyder RD.

Toxicol Pathol. 2010 Aug;38(5):738-44. doi: 10.1177/0192623310374331. Epub 2010 Jun 28.

PMID:
20585143
12.

ABCG2-associated resistance to Hoechst 33342 and topotecan in a murine cell model with constitutive expression of side population characteristics.

Smith PJ, Furon E, Wiltshire M, Campbell L, Feeney GP, Snyder RD, Errington RJ.

Cytometry A. 2009 Nov;75(11):924-33. doi: 10.1002/cyto.a.20800.

13.

Lovastatin enhances the genotoxicity of doxorubicin in Chinese hamster V79 cells via noncovalent DNA binding.

Snyder RD.

Drug Chem Toxicol. 2009;32(1):17-20. doi: 10.1080/01480540802433948.

PMID:
19514934
14.

Characterization and interlaboratory comparison of a gene expression signature for differentiating genotoxic mechanisms.

Ellinger-Ziegelbauer H, Fostel JM, Aruga C, Bauer D, Boitier E, Deng S, Dickinson D, Le Fevre AC, Fornace AJ Jr, Grenet O, Gu Y, Hoflack JC, Shiiyama M, Smith R, Snyder RD, Spire C, Tanaka G, Aubrecht J.

Toxicol Sci. 2009 Aug;110(2):341-52. doi: 10.1093/toxsci/kfp103. Epub 2009 May 22.

15.

An assessment of the carcinogenic potential of ezetimibe using nonclinical data in a weight-of-evidence approach.

Halleck M, Davis HR, Kirschmeier P, Levitan D, Snyder RD, Treinen K, Macdonald JS.

Toxicology. 2009 Apr 28;258(2-3):116-30. doi: 10.1016/j.tox.2009.01.017. Epub 2009 Jan 22.

PMID:
19428931
16.

Predictive models for carcinogenicity and mutagenicity: frameworks, state-of-the-art, and perspectives.

Benfenati E, Benigni R, Demarini DM, Helma C, Kirkland D, Martin TM, Mazzatorta P, Ou├ędraogo-Arras G, Richard AM, Schilter B, Schoonen WG, Snyder RD, Yang C.

J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2009 Apr;27(2):57-90. doi: 10.1080/10590500902885593. Review.

PMID:
19412856
17.

An update on the genotoxicity and carcinogenicity of marketed pharmaceuticals with reference to in silico predictivity.

Snyder RD.

Environ Mol Mutagen. 2009 Jul;50(6):435-50. doi: 10.1002/em.20485.

PMID:
19334052
18.

Erratum to "Prediction of non-genotoxic carcinogenesis in rats using changes in gene expression following acute dosing".

Nioi P, Pardo ID, Sherratt PJ, Fielden MR, Gollub J, Nie A, Snyder RD.

Chem Biol Interact. 2008 Nov 25;176(2-3):252-60.

PMID:
19086139
19.

Monitoring the accumulation of fluorescently labeled phospholipids in cell cultures provides an accurate screen for drugs that induce phospholipidosis.

Nioi P, Pardo ID, Snyder RD.

Drug Chem Toxicol. 2008;31(4):515-28. doi: 10.1080/01480540802391229 .

PMID:
18850360
20.

Temporal evaluation of CYP mRNA in mice administered with prototypical P450 inducers: comparison with conventional protein/enzyme methods.

Wang EJ, Mandakas G, Palamanda J, Lin X, Kumari P, Chu I, Soares A, Smith RJ, Snyder RD, Gu YZ.

Drug Chem Toxicol. 2008;31(4):501-13. doi: 10.1080/01480540802390825 .

PMID:
18850359
21.

Histopathology of vascular injury in Sprague-Dawley rats treated with phosphodiesterase IV inhibitor SCH 351591 or SCH 534385.

Zhang J, Snyder RD, Herman EH, Knapton A, Honchel R, Miller T, Espandiari P, Goodsaid FM, Rosenblum IY, Hanig JP, Sistare FD, Weaver JL.

Toxicol Pathol. 2008 Oct;36(6):827-39. doi: 10.1177/0192623308322308. Epub 2008 Sep 5.

PMID:
18776163
22.

Prediction of non-genotoxic carcinogenesis in rats using changes in gene expression following acute dosing.

Nioi P, Pardo ID, Sherratt PJ, Snyder RD.

Chem Biol Interact. 2008 Apr 15;172(3):206-15. doi: 10.1016/j.cbi.2008.01.009. Epub 2008 Feb 1. Corrected and republished in: Chem Biol Interact. 2008 Nov 25;176(2-3):252-60.

PMID:
18328469
23.

Validation of putative genomic biomarkers of nephrotoxicity in rats.

Wang EJ, Snyder RD, Fielden MR, Smith RJ, Gu YZ.

Toxicology. 2008 Apr 18;246(2-3):91-100. doi: 10.1016/j.tox.2007.12.031. Epub 2008 Jan 16.

PMID:
18289764
24.

In vitro detection of drug-induced phospholipidosis using gene expression and fluorescent phospholipid based methodologies.

Nioi P, Perry BK, Wang EJ, Gu YZ, Snyder RD.

Toxicol Sci. 2007 Sep;99(1):162-73. Epub 2007 Jun 12.

PMID:
17567588
25.

Assessment of atypical DNA intercalating agents in biological and in silico systems.

Snyder RD.

Mutat Res. 2007 Oct 1;623(1-2):72-82. Epub 2007 Mar 12. Review.

PMID:
17434187
26.

Supportive-expressive group therapy for women with metastatic breast cancer: survival and psychosocial outcome from a randomized controlled trial.

Kissane DW, Grabsch B, Clarke DM, Smith GC, Love AW, Bloch S, Snyder RD, Li Y.

Psychooncology. 2007 Apr;16(4):277-86.

PMID:
17385190
27.

Toxicogenomics in drug discovery and development: mechanistic analysis of compound/class-dependent effects using the DrugMatrix database.

Ganter B, Snyder RD, Halbert DN, Lee MD.

Pharmacogenomics. 2006 Oct;7(7):1025-44. Review.

PMID:
17054413
28.

Information from the Internet: attitudes of Australian oncology patients.

Newnham GM, Burns WI, Snyder RD, Dowling AJ, Ranieri NF, Gray EL, McLachlan SA.

Intern Med J. 2006 Nov;36(11):718-23.

PMID:
17040358
29.

Psychological morbidity and quality of life in women with advanced breast cancer: a cross-sectional survey.

Grabsch B, Clarke DM, Love A, McKenzie DP, Snyder RD, Bloch S, Smith G, Kissane DW.

Palliat Support Care. 2006 Mar;4(1):47-56.

PMID:
16889323
30.

DNA intercalative potential of marketed drugs testing positive in in vitro cytogenetics assays.

Snyder RD, Ewing D, Hendry LB.

Mutat Res. 2006 Oct 10;609(1):47-59. Epub 2006 Jul 20.

PMID:
16857419
31.

SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells.

Aardema MJ, Snyder RD, Spicer C, Divi K, Morita T, Mauthe RJ, Gibson DP, Soelter S, Curry PT, Thybaud V, Lorenzon G, Marzin D, Lorge E.

Mutat Res. 2006 Aug 4;607(1):61-87. Epub 2006 Jun 21.

PMID:
16797224
32.

American Academy of Neurology qualifications and guidelines for the physician expert witness.

Williams MA, Mackin GA, Beresford HR, Gordon J, Jacobson PL, McQuillen MP, Reimschisel TE, Taylor RM, Bernat JL, Rizzo M, Snyder RD, Sagsveen MG, Amery M, Brannon WL Jr; American Academy of Neurology.

Neurology. 2006 Jan 10;66(1):13-4. No abstract available.

PMID:
16401838
33.

Hypoxia-induced micronucleus formation in mice.

Snyder RD, Diehl MS.

Drug Chem Toxicol. 2005;28(4):373-8.

PMID:
16298869
34.

Computational prediction of genotoxicity: room for improvement.

Snyder RD, Smith MD.

Drug Discov Today. 2005 Aug 15;10(16):1119-24. Review.

PMID:
16182197
35.

Attitudes of oncology health professionals to information from the Internet and other media.

Newnham GM, Burns WI, Snyder RD, Dowling AJ, Ranieri NF, Gray EL, McLachlan SA.

Med J Aust. 2005 Aug 15;183(4):197-200.

PMID:
16097920
36.

The influence of N-dialkyl and other cationic substituents on DNA intercalation and genotoxicity.

Snyder RD, McNulty J, Zairov G, Ewing DE, Hendry LB.

Mutat Res. 2005 Oct 15;578(1-2):88-99. Epub 2005 Jun 28.

PMID:
15990125
37.

5-(3-Bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-ylamine: structure-activity relationships of 7-substituted heteroaryl analogs as non-nucleoside adenosine kinase inhibitors.

Matulenko MA, Lee CH, Jiang M, Frey RR, Cowart MD, Bayburt EK, Didomenico S, Gfesser GA, Gomtsyan A, Zheng GZ, McKie JA, Stewart AO, Yu H, Kohlhaas KL, Alexander KM, McGaraughty S, Wismer CT, Mikusa J, Marsh KC, Snyder RD, Diehl MS, Kowaluk EA, Jarvis MF, Bhagwat SS.

Bioorg Med Chem. 2005 Jun 1;13(11):3705-20.

PMID:
15863000
38.
39.

Effect of cognitive-existential group therapy on survival in early-stage breast cancer.

Kissane DW, Love A, Hatton A, Bloch S, Smith G, Clarke DM, Miach P, Ikin J, Ranieri N, Snyder RD.

J Clin Oncol. 2004 Nov 1;22(21):4255-60. Epub 2004 Sep 27.

PMID:
15452189
40.
41.

New concepts in breast cancer therapy.

Snyder RD.

Intern Med J. 2004 May;34(5):266-9. Review.

PMID:
15151673
42.

Assessment of the sensitivity of the computational programs DEREK, TOPKAT, and MCASE in the prediction of the genotoxicity of pharmaceutical molecules.

Snyder RD, Pearl GS, Mandakas G, Choy WN, Goodsaid F, Rosenblum IY.

Environ Mol Mutagen. 2004;43(3):143-58. Erratum in: Environ Mol Mutagen. 2006 Apr;47(3):225.

PMID:
15065202
43.

Nephrotic syndrome associated with carcinoma of the breast.

Hill PA, Goodman DG, Snyder RD.

Clin Nephrol. 2003 Dec;60(6):437-8. No abstract available.

PMID:
14690264
44.

Bacterial meningitis: diagnosis and treatment.

Snyder RD.

Curr Neurol Neurosci Rep. 2003 Nov;3(6):461-9. Review.

PMID:
14565899
45.

Reduction of genistein clastogenicity in Chinese hamster V79 cells by daidzein and other flavonoids.

Snyder RD, Gillies PJ.

Food Chem Toxicol. 2003 Oct;41(10):1291-8.

PMID:
12909261
48.
50.

Teaching ethics to trainees.

Snyder RD.

Semin Pediatr Neurol. 2002 Mar;9(1):62-6.

PMID:
11931128

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