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Items: 1 to 50 of 207

1.

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate.

Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller KD, Schug ZT, Snyder NW, Gade TP, Titchenell PM, Rabinowitz JD, Wellen KE.

Nature. 2020 Mar;579(7800):586-591. doi: 10.1038/s41586-020-2101-7. Epub 2020 Mar 18.

PMID:
32214246
2.

Compartmentalised acyl-CoA metabolism and roles in chromatin regulation.

Trefely S, Lovell CD, Snyder NW, Wellen KE.

Mol Metab. 2020 Feb 14:100941. doi: 10.1016/j.molmet.2020.01.005. [Epub ahead of print]

3.

Prophylactic Antiviral Activity of Sulfated Glycomimetic Oligomers and Polymers.

Soria-Martinez L, Bauer S, Giesler M, Schelhaas S, Materlik J, Janus K, Pierzyna P, Becker M, Snyder NL, Hartmann L, Schelhaas M.

J Am Chem Soc. 2020 Mar 18;142(11):5252-5265. doi: 10.1021/jacs.9b13484. Epub 2020 Mar 10.

PMID:
32105452
4.

mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.

Martinez Calejman C, Trefely S, Entwisle SW, Luciano A, Jung SM, Hsiao W, Torres A, Hung CM, Li H, Snyder NW, Villén J, Wellen KE, Guertin DA.

Nat Commun. 2020 Jan 29;11(1):575. doi: 10.1038/s41467-020-14430-w.

5.

Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response.

Uribe-Herranz M, Rafail S, Beghi S, Gil-de-Gómez L, Verginadis I, Bittinger K, Pustylnikov S, Pierini S, Perales-Linares R, Blair IA, Mesaros CA, Snyder NW, Bushman F, Koumenis C, Facciabene A.

J Clin Invest. 2020 Jan 2;130(1):466-479. doi: 10.1172/JCI124332.

6.

Recovery, Purification, and Reusability of Building Blocks for Solid Phase Synthesis.

Shamout F, Fischer L, Snyder NL, Hartmann L.

Macromol Rapid Commun. 2020 Jan;41(2):e1900473. doi: 10.1002/marc.201900473. Epub 2019 Dec 3.

PMID:
31794100
7.

Subcellular metabolic pathway kinetics are revealed by correcting for artifactual post harvest metabolism.

Trefely S, Liu J, Huber K, Doan MT, Jiang H, Singh J, von Krusenstiern E, Bostwick A, Xu P, Bogner-Strauss JG, Wellen KE, Snyder NW.

Mol Metab. 2019 Dec;30:61-71. doi: 10.1016/j.molmet.2019.09.004. Epub 2019 Sep 27.

8.

Crosstalk between cellular metabolism and histone acetylation.

Trefely S, Doan MT, Snyder NW.

Methods Enzymol. 2019;626:1-21. doi: 10.1016/bs.mie.2019.07.013. Epub 2019 Aug 12.

PMID:
31606071
9.

Author Correction: Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses.

Langston PK, Nambu A, Jung J, Shibata M, Aksoylar HI, Lei J, Xu P, Doan MT, Jiang H, MacArthur MR, Gao X, Kong Y, Chouchani ET, Locasale JW, Snyder NW, Horng T.

Nat Immunol. 2019 Nov;20(11):1555. doi: 10.1038/s41590-019-0517-8.

PMID:
31551573
10.

Malate-aspartate shuttle promotes l-lactate oxidation in mitochondria.

Altinok O, Poggio JL, Stein DE, Bowne WB, Shieh AC, Snyder NW, Orynbayeva Z.

J Cell Physiol. 2020 Mar;235(3):2569-2581. doi: 10.1002/jcp.29160. Epub 2019 Sep 6.

PMID:
31490559
11.

Comparing Balance Control Between Soccer Players and Non-Athletes During a Dynamic Lower Limb Reaching Task.

Snyder N, Cinelli M.

Res Q Exerc Sport. 2020 Mar;91(1):166-171. doi: 10.1080/02701367.2019.1649356. Epub 2019 Sep 3.

PMID:
31479412
12.

A superoxide scavenging coating for improving tissue response to neural implants.

Zheng XS, Snyder NR, Woeppel K, Barengo JH, Li X, Eles J, Kolarcik CL, Cui XT.

Acta Biomater. 2019 Nov;99:72-83. doi: 10.1016/j.actbio.2019.08.032. Epub 2019 Aug 22.

PMID:
31446048
13.

Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming.

Buj R, Chen CW, Dahl ES, Leon KE, Kuskovsky R, Maglakelidze N, Navaratnarajah M, Zhang G, Doan MT, Jiang H, Zaleski M, Kutzler L, Lacko H, Lu Y, Mills GB, Gowda R, Robertson GP, Warrick JI, Herlyn M, Imamura Y, Kimball SR, DeGraff DJ, Snyder NW, Aird KM.

Cell Rep. 2019 Aug 20;28(8):1971-1980.e8. doi: 10.1016/j.celrep.2019.07.084.

14.

Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses.

Langston PK, Nambu A, Jung J, Shibata M, Aksoylar HI, Lei J, Xu P, Doan MT, Jiang H, MacArthur MR, Gao X, Kong Y, Chouchani ET, Locasale JW, Snyder NW, Horng T.

Nat Immunol. 2019 Sep;20(9):1186-1195. doi: 10.1038/s41590-019-0453-7. Epub 2019 Aug 5. Erratum in: Nat Immunol. 2019 Sep 24;:.

15.

Should we consider subcellular compartmentalization of metabolites, and if so, how do we measure them?

Wellen KE, Snyder NW.

Curr Opin Clin Nutr Metab Care. 2019 Sep;22(5):347-354. doi: 10.1097/MCO.0000000000000580.

PMID:
31365463
16.

Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy.

Kopinski PK, Janssen KA, Schaefer PM, Trefely S, Perry CE, Potluri P, Tintos-Hernandez JA, Singh LN, Karch KR, Campbell SL, Doan MT, Jiang H, Nissim I, Nakamaru-Ogiso E, Wellen KE, Snyder NW, Garcia BA, Wallace DC.

Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):16028-16035. doi: 10.1073/pnas.1906896116. Epub 2019 Jun 28.

17.

Association of serum androgens and coronary artery calcium scores in women.

Penn CA, Chan J, Mesaros C, Snyder NW, Rader DJ, Sammel MD, Dokras A.

Fertil Steril. 2019 Sep;112(3):586-593. doi: 10.1016/j.fertnstert.2019.04.024. Epub 2019 Jun 11.

PMID:
31200968
18.

A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate.

Wang W, Ishibashi J, Trefely S, Shao M, Cowan AJ, Sakers A, Lim HW, O'Connor S, Doan MT, Cohen P, Baur JA, King MT, Veech RL, Won KJ, Rabinowitz JD, Snyder NW, Gupta RK, Seale P.

Cell Metab. 2019 Jul 2;30(1):174-189.e5. doi: 10.1016/j.cmet.2019.05.005. Epub 2019 May 30.

PMID:
31155495
19.

How to Write an Effective Results Section.

Snyder N, Foltz C, Lendner M, Vaccaro AR.

Clin Spine Surg. 2019 Aug;32(7):295-296. doi: 10.1097/BSD.0000000000000845.

PMID:
31145152
20.

Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females.

Fernandez S, Viola JM, Torres A, Wallace M, Trefely S, Zhao S, Affronti HC, Gengatharan JM, Guertin DA, Snyder NW, Metallo CM, Wellen KE.

Cell Rep. 2019 May 28;27(9):2772-2784.e6. doi: 10.1016/j.celrep.2019.04.112.

21.

Minimum predicted distance: Applying a common metric to collision avoidance strategies between children and adult walkers.

Rapos V, Cinelli M, Snyder N, Crétual A, Olivier AH.

Gait Posture. 2019 Jul;72:16-21. doi: 10.1016/j.gaitpost.2019.05.016. Epub 2019 May 22.

22.

Targeting IDH1 as a Prosenescent Therapy in High-grade Serous Ovarian Cancer.

Dahl ES, Buj R, Leon KE, Newell JM, Imamura Y, Bitler BG, Snyder NW, Aird KM.

Mol Cancer Res. 2019 Aug;17(8):1710-1720. doi: 10.1158/1541-7786.MCR-18-1233. Epub 2019 May 20.

PMID:
31110157
23.

Preliminary results of identification and quantification of paclitaxel and its metabolites in human meconium from newborns with gestational chemotherapeutic exposure.

Cardonick E, Broadrup R, Xu P, Doan MT, Jiang H, Snyder NW.

PLoS One. 2019 Feb 20;14(2):e0211821. doi: 10.1371/journal.pone.0211821. eCollection 2019.

24.

Auxin-Inducible Depletion of the Essentialome Suggests Inhibition of TORC1 by Auxins and Inhibition of Vrg4 by SDZ 90-215, a Natural Antifungal Cyclopeptide.

Snyder NA, Kim A, Kester L, Gale AN, Studer C, Hoepfner D, Roggo S, Helliwell SB, Cunningham KW.

G3 (Bethesda). 2019 Mar 7;9(3):829-840. doi: 10.1534/g3.118.200748.

25.

Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal.

Liu M, O'Connor RS, Trefely S, Graham K, Snyder NW, Beatty GL.

Nat Immunol. 2019 Jan 21;20(3):265-275. doi: 10.1038/s41590-018-0292-y.

26.

Safety, pharmacodynamics, and potential benefit of omaveloxolone in Friedreich ataxia.

Lynch DR, Farmer J, Hauser L, Blair IA, Wang QQ, Mesaros C, Snyder N, Boesch S, Chin M, Delatycki MB, Giunti P, Goldsberry A, Hoyle C, McBride MG, Nachbauer W, O'Grady M, Perlman S, Subramony SH, Wilmot GR, Zesiewicz T, Meyer C.

Ann Clin Transl Neurol. 2018 Nov 10;6(1):15-26. doi: 10.1002/acn3.660. eCollection 2019 Jan.

27.

Comparison of the Polar V800 and the Garmin Forerunner 230 to Predict V[Combining Dot Above]O2max.

Snyder NC, Willoughby CA, Smith BK.

J Strength Cond Res. 2019 Jan 10. doi: 10.1519/JSC.0000000000002931. [Epub ahead of print]

PMID:
30640299
28.

Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis.

Carrer A, Trefely S, Zhao S, Campbell SL, Norgard RJ, Schultz KC, Sidoli S, Parris JLD, Affronti HC, Sivanand S, Egolf S, Sela Y, Trizzino M, Gardini A, Garcia BA, Snyder NW, Stanger BZ, Wellen KE.

Cancer Discov. 2019 Mar;9(3):416-435. doi: 10.1158/2159-8290.CD-18-0567. Epub 2019 Jan 9.

29.

Milk biosynthesis requires the Golgi cation exchanger TMEM165.

Snyder NA, Palmer MV, Reinhardt TA, Cunningham KW.

J Biol Chem. 2019 Mar 1;294(9):3181-3191. doi: 10.1074/jbc.RA118.006270. Epub 2019 Jan 8.

30.

Simultaneous isotope dilution quantification and metabolic tracing of deoxyribonucleotides by liquid chromatography high resolution mass spectrometry.

Kuskovsky R, Buj R, Xu P, Hofbauer S, Doan MT, Jiang H, Bostwick A, Mesaros C, Aird KM, Snyder NW.

Anal Biochem. 2019 Mar 1;568:65-72. doi: 10.1016/j.ab.2018.12.023. Epub 2018 Dec 31.

PMID:
30605633
31.

N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.

Huber K, Hofer DC, Trefely S, Pelzmann HJ, Madreiter-Sokolowski C, Duta-Mare M, Schlager S, Trausinger G, Stryeck S, Graier WF, Kolb D, Magnes C, Snyder NW, Prokesch A, Kratky D, Madl T, Wellen KE, Bogner-Strauss JG.

Biochim Biophys Acta Mol Cell Res. 2019 Mar;1866(3):337-348. doi: 10.1016/j.bbamcr.2018.08.017. Epub 2018 Aug 31.

32.

Distinct Roles of GluA2-lacking AMPA Receptor Expression in Dopamine D1 or D2 Receptor Neurons in Animal Behavior.

Shou J, Tran A, Snyder N, Bleem E, Kim S.

Neuroscience. 2019 Feb 1;398:102-112. doi: 10.1016/j.neuroscience.2018.12.002. Epub 2018 Dec 8.

PMID:
30537522
33.

Tryptophan 32 mediates SOD1 toxicity in a in vivo motor neuron model of ALS and is a promising target for small molecule therapeutics.

DuVal MG, Hinge VK, Snyder N, Kanyo R, Bratvold J, Pokrishevsky E, Cashman NR, Blinov N, Kovalenko A, Allison WT.

Neurobiol Dis. 2019 Apr;124:297-310. doi: 10.1016/j.nbd.2018.11.025. Epub 2018 Dec 4.

PMID:
30528257
34.

Heteromultivalent Glycooligomers as Mimetics of Blood Group Antigens.

Bücher KS, Konietzny PB, Snyder NL, Hartmann L.

Chemistry. 2019 Mar 1;25(13):3301-3309. doi: 10.1002/chem.201804505. Epub 2019 Feb 7.

PMID:
30431195
35.

Evaluation of Escherichia coli pathotypes associated with irritable bowel syndrome.

Dogan B, Belcher-Timme HF, Dogan EI, Jiang ZD, DuPont HL, Snyder N, Yang S, Chandler B, Scherl EJ, Simpson KW.

FEMS Microbiol Lett. 2018 Nov 1;365(22). doi: 10.1093/femsle/fny249.

PMID:
30299475
36.

Gestational Diabetes Alters the Metabolomic Profile in 2nd Trimester Amniotic Fluid in a Sex-Specific Manner.

O'Neill K, Alexander J, Azuma R, Xiao R, Snyder NW, Mesaros CA, Blair IA, Pinney SE.

Int J Mol Sci. 2018 Sep 10;19(9). pii: E2696. doi: 10.3390/ijms19092696.

37.

Oral nitrite restores age-dependent phenotypes in eNOS-null mice.

Tenopoulou M, Doulias PT, Nakamoto K, Berrios K, Zura G, Li C, Faust M, Yakovishina V, Evans P, Tan L, Bennett MJ, Snyder NW, Quinn WJ 3rd, Baur JA, Atochin DN, Huang PL, Ischiropoulos H.

JCI Insight. 2018 Aug 23;3(16). pii: 122156. doi: 10.1172/jci.insight.122156. eCollection 2018 Aug 23.

38.

CaGdt1 plays a compensatory role for the calcium pump CaPmr1 in the regulation of calcium signaling and cell wall integrity signaling in Candida albicans.

Jiang L, Wang J, Asghar F, Snyder N, Cunningham KW.

Cell Commun Signal. 2018 Jun 28;16(1):33. doi: 10.1186/s12964-018-0246-x.

39.

Mice exposed to bisphenol A exhibit depressive-like behavior with neurotransmitter and neuroactive steroid dysfunction.

Xin F, Fischer E, Krapp C, Krizman EN, Lan Y, Mesaros C, Snyder NW, Bansal A, Robinson MB, Simmons RA, Bartolomei MS.

Horm Behav. 2018 Jun;102:93-104. doi: 10.1016/j.yhbeh.2018.05.010. Epub 2018 May 18.

40.

Artefactual formation of pyruvate from in-source conversion of lactate.

Trefely S, Mesaros C, Xu P, Doan MT, Jiang H, Altinok O, Orynbayeva Z, Snyder NW.

Rapid Commun Mass Spectrom. 2018 May 8. doi: 10.1002/rcm.8159. [Epub ahead of print]

41.

Search for Neutrinoless Double-β Decay in ^{76}Ge with the Majorana Demonstrator.

Aalseth CE, Abgrall N, Aguayo E, Alvis SI, Amman M, Arnquist IJ, Avignone FT, Back HO, Barabash AS, Barbeau PS, Barton CJ, Barton PJ, Bertrand FE, Bode T, Bos B, Boswell M, Bradley AW, Brodzinski RL, Brudanin V, Busch M, Buuck M, Caldwell AS, Caldwell TS, Chan YD, Christofferson CD, Chu PH, Collar JI, Combs DC, Cooper RJ, Cuesta C, Detwiler JA, Doe PJ, Dunmore JA, Efremenko Y, Ejiri H, Elliott SR, Fast JE, Finnerty P, Fraenkle FM, Fu Z, Fujikawa BK, Fuller E, Galindo-Uribarri A, Gehman VM, Gilliss T, Giovanetti GK, Goett J, Green MP, Gruszko J, Guinn IS, Guiseppe VE, Hallin AL, Haufe CR, Hehn L, Henning R, Hoppe EW, Hossbach TW, Howe MA, Jasinski BR, Johnson RA, Keeter KJ, Kephart JD, Kidd MF, Knecht A, Konovalov SI, Kouzes RT, LaFerriere BD, Leon J, Lesko KT, Leviner LE, Loach JC, Lopez AM, Luke PN, MacMullin J, MacMullin S, Marino MG, Martin RD, Massarczyk R, McDonald AB, Mei DM, Meijer SJ, Merriman JH, Mertens S, Miley HS, Miller ML, Myslik J, Orrell JL, O'Shaughnessy C, Othman G, Overman NR, Perumpilly G, Pettus W, Phillips DG, Poon AWP, Pushkin K, Radford DC, Rager J, Reeves JH, Reine AL, Rielage K, Robertson RGH, Ronquest MC, Ruof NW, Schubert AG, Shanks B, Shirchenko M, Snavely KJ, Snyder N, Steele D, Suriano AM, Tedeschi D, Tornow W, Trimble JE, Varner RL, Vasilyev S, Vetter K, Vorren K, White BR, Wilkerson JF, Wiseman C, Xu W, Yakushev E, Yaver H, Young AR, Yu CH, Yumatov V, Zhitnikov I, Zhu BX, Zimmermann S; Majorana Collaboration.

Phys Rev Lett. 2018 Mar 30;120(13):132502. doi: 10.1103/PhysRevLett.120.132502.

42.

Bioorthogonal pro-metabolites for profiling short chain fatty acylation.

Sinclair WR, Shrimp JH, Zengeya TT, Kulkarni RA, Garlick JM, Luecke H, Worth AJ, Blair IA, Snyder NW, Meier JL.

Chem Sci. 2017 Dec 8;9(5):1236-1241. doi: 10.1039/c7sc00247e. eCollection 2018 Feb 7.

43.

The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations.

O'Connor RS, Guo L, Ghassemi S, Snyder NW, Worth AJ, Weng L, Kam Y, Philipson B, Trefely S, Nunez-Cruz S, Blair IA, June CH, Milone MC.

Sci Rep. 2018 Apr 19;8(1):6289. doi: 10.1038/s41598-018-24676-6.

44.

Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+-NFAT signaling.

Lee JV, Berry CT, Kim K, Sen P, Kim T, Carrer A, Trefely S, Zhao S, Fernandez S, Barney LE, Schwartz AD, Peyton SR, Snyder NW, Berger SL, Freedman BD, Wellen KE.

Genes Dev. 2018 Apr 1;32(7-8):497-511. doi: 10.1101/gad.311027.117. Epub 2018 Apr 19.

45.

Lipid Synthesis Is Required to Resolve Endoplasmic Reticulum Stress and Limit Fibrotic Responses in the Lung.

Romero F, Hong X, Shah D, Kallen CB, Rosas I, Guo Z, Schriner D, Barta J, Shaghaghi H, Hoek JB, Mesaros C, Choi AM, Snyder NW, Summer R.

Am J Respir Cell Mol Biol. 2018 Aug;59(2):225-236. doi: 10.1165/rcmb.2017-0340OC.

46.

Low apolipoprotein A-I levels in Friedreich's ataxia and in frataxin-deficient cells: Implications for therapy.

Wang Q, Guo L, Strawser CJ, Hauser LA, Hwang WT, Snyder NW, Lynch DR, Mesaros C, Blair IA.

PLoS One. 2018 Feb 15;13(2):e0192779. doi: 10.1371/journal.pone.0192779. eCollection 2018.

47.

ROS responsive resveratrol delivery from LDLR peptide conjugated PLA-coated mesoporous silica nanoparticles across the blood-brain barrier.

Shen Y, Cao B, Snyder NR, Woeppel KM, Eles JR, Cui XT.

J Nanobiotechnology. 2018 Feb 13;16(1):13. doi: 10.1186/s12951-018-0340-7.

48.

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.

Bartelt A, Widenmaier SB, Schlein C, Johann K, Goncalves RLS, Eguchi K, Fischer AW, Parlakgül G, Snyder NA, Nguyen TB, Bruns OT, Franke D, Bawendi MG, Lynes MD, Leiria LO, Tseng YH, Inouye KE, Arruda AP, Hotamisligil GS.

Nat Med. 2018 Mar;24(3):292-303. doi: 10.1038/nm.4481. Epub 2018 Feb 5.

49.

Defining Metabolic and Nonmetabolic Regulation of Histone Acetylation by NSAID Chemotypes.

Shrimp JH, Garlick JM, Tezil T, Sorum AW, Worth AJ, Blair IA, Verdin E, Snyder NW, Meier JL.

Mol Pharm. 2018 Mar 5;15(3):729-736. doi: 10.1021/acs.molpharmaceut.7b00943. Epub 2017 Dec 29.

50.

NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis.

Widenmaier SB, Snyder NA, Nguyen TB, Arduini A, Lee GY, Arruda AP, Saksi J, Bartelt A, Hotamisligil GS.

Cell. 2017 Nov 16;171(5):1094-1109.e15. doi: 10.1016/j.cell.2017.10.003.

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