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Items: 1 to 50 of 107

1.

Phenotypic proteomic profiling identifies a landscape of targets for circadian clock-modulating compounds.

Ray S, Lach R, Heesom KJ, Valekunja UK, Encheva V, Snijders AP, Reddy AB.

Life Sci Alliance. 2019 Dec 2;2(6). pii: e201900603. doi: 10.26508/lsa.201900603. Print 2019 Dec.

2.

CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle.

Sarek G, Kotsantis P, Ruis P, Van Ly D, Margalef P, Borel V, Zheng XF, Flynn HR, Snijders AP, Chowdhury D, Cesare AJ, Boulton SJ.

Nature. 2019 Nov;575(7783):523-527. doi: 10.1038/s41586-019-1744-8. Epub 2019 Nov 13.

3.

Cdc14 and PP2A Phosphatases Cooperate to Shape Phosphoproteome Dynamics during Mitotic Exit.

Touati SA, Hofbauer L, Jones AW, Snijders AP, Kelly G, Uhlmann F.

Cell Rep. 2019 Nov 12;29(7):2105-2119.e4. doi: 10.1016/j.celrep.2019.10.041.

4.

CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth.

Wang VM, Ferreira RMM, Almagro J, Evan T, Legrave N, Zaw Thin M, Frith D, Carvalho J, Barry DJ, Snijders AP, Herbert E, Nye EL, MacRae JI, Behrens A.

Nat Cell Biol. 2019 Nov;21(11):1425-1435. doi: 10.1038/s41556-019-0407-1. Epub 2019 Nov 4.

PMID:
31685994
5.

Casein kinase 1 family proteins promote Slimb-dependent Expanded degradation.

Fulford AD, Holder MV, Frith D, Snijders AP, Tapon N, Ribeiro PS.

Elife. 2019 Sep 30;8. pii: e46592. doi: 10.7554/eLife.46592.

6.

LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly.

Attig J, Young GR, Hosie L, Perkins D, Encheva-Yokoya V, Stoye JP, Snijders AP, Ternette N, Kassiotis G.

Genome Res. 2019 Oct;29(10):1578-1590. doi: 10.1101/gr.248922.119. Epub 2019 Sep 19.

7.

Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism.

Serafini A, Tan L, Horswell S, Howell S, Greenwood DJ, Hunt DM, Phan MD, Schembri M, Monteleone M, Montague CR, Britton W, Garza-Garcia A, Snijders AP, VanderVen B, Gutierrez MG, West NP, de Carvalho LPS.

Mol Microbiol. 2019 Oct;112(4):1284-1307. doi: 10.1111/mmi.14362. Epub 2019 Aug 23.

8.

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation.

Macpherson JA, Theisen A, Masino L, Fets L, Driscoll PC, Encheva V, Snijders AP, Martin SR, Kleinjung J, Barran PE, Fraternali F, Anastasiou D.

Elife. 2019 Jul 2;8. pii: e45068. doi: 10.7554/eLife.45068.

9.

Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites.

Knuepfer E, Wright KE, Kumar Prajapati S, Rawlinson TA, Mohring F, Koch M, Lyth OR, Howell SA, Villasis E, Snijders AP, Moon RW, Draper SJ, Rosanas-Urgell A, Higgins MK, Baum J, Holder AA.

PLoS Pathog. 2019 Jun 11;15(6):e1007809. doi: 10.1371/journal.ppat.1007809. eCollection 2019 Jun.

10.

Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery.

Patel A, Perrin AJ, Flynn HR, Bisson C, Withers-Martinez C, Treeck M, Flueck C, Nicastro G, Martin SR, Ramos A, Gilberger TW, Snijders AP, Blackman MJ, Baker DA.

PLoS Biol. 2019 May 10;17(5):e3000264. doi: 10.1371/journal.pbio.3000264. eCollection 2019 May.

11.

An Integrated Chemical Proteomics Approach for Quantitative Profiling of Intracellular ADP-Ribosylation.

Kalesh K, Lukauskas S, Borg AJ, Snijders AP, Ayyappan V, Leung AKL, Haskard DO, DiMaggio PA.

Sci Rep. 2019 Apr 30;9(1):6655. doi: 10.1038/s41598-019-43154-1.

12.

ATG9A shapes the forming autophagosome through Arfaptin 2 and phosphatidylinositol 4-kinase IIIβ.

Judith D, Jefferies HBJ, Boeing S, Frith D, Snijders AP, Tooze SA.

J Cell Biol. 2019 May 6;218(5):1634-1652. doi: 10.1083/jcb.201901115. Epub 2019 Mar 27.

13.

Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion.

Flueck C, Drought LG, Jones A, Patel A, Perrin AJ, Walker EM, Nofal SD, Snijders AP, Blackman MJ, Baker DA.

PLoS Biol. 2019 Feb 22;17(2):e3000154. doi: 10.1371/journal.pbio.3000154. eCollection 2019 Feb.

14.

Analysis of RNA polymerase II ubiquitylation and proteasomal degradation.

Tufegdzic Vidakovic A, Harreman M, Dirac-Svejstrup AB, Boeing S, Roy A, Encheva V, Neumann M, Wilson M, Snijders AP, Svejstrup JQ.

Methods. 2019 Apr 15;159-160:146-156. doi: 10.1016/j.ymeth.2019.02.005. Epub 2019 Feb 13.

15.

The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7.

Köhler K, Sanchez-Pulido L, Höfer V, Marko A, Ponting CP, Snijders AP, Feederle R, Schepers A, Boos D.

PLoS Biol. 2019 Jan 29;17(1):e2006767. doi: 10.1371/journal.pbio.2006767. eCollection 2019 Jan.

16.

LUBAC determines chemotherapy resistance in squamous cell lung cancer.

Ruiz EJ, Diefenbacher ME, Nelson JK, Sancho R, Pucci F, Chakraborty A, Moreno P, Annibaldi A, Liccardi G, Encheva V, Mitter R, Rosenfeldt M, Snijders AP, Meier P, Calzado MA, Behrens A.

J Exp Med. 2019 Feb 4;216(2):450-465. doi: 10.1084/jem.20180742. Epub 2019 Jan 14.

17.

Chemical genetic identification of GAK substrates reveals its role in regulating Na+/K+-ATPase.

Lin AW, Gill KK, Castañeda MS, Matucci I, Eder N, Claxton S, Flynn H, Snijders AP, George R, Ultanir SK.

Life Sci Alliance. 2018 Dec 31;1(6):e201800118. doi: 10.26508/lsa.201800118. eCollection 2018 Dec.

18.

Repression of Divergent Noncoding Transcription by a Sequence-Specific Transcription Factor.

Wu ACK, Patel H, Chia M, Moretto F, Frith D, Snijders AP, van Werven FJ.

Mol Cell. 2018 Dec 20;72(6):942-954.e7. doi: 10.1016/j.molcel.2018.10.018.

19.

Author Correction: Bi-directional cell-pericellular matrix interactions direct stem cell fate.

Ferreira SA, Motwani MS, Faull PA, Seymour AJ, Yu TTL, Enayati M, Taheem DK, Salzlechner C, Haghighi T, Kania EM, Oommen OP, Ahmed T, Loaiza S, Parzych K, Dazzi F, Varghese OP, Festy F, Grigoriadis AE, Auner HW, Snijders AP, Bozec L, Gentleman E.

Nat Commun. 2018 Dec 18;9(1):5419. doi: 10.1038/s41467-018-07843-1.

20.

Author Correction: Bi-directional cell-pericellular matrix interactions direct stem cell fate.

Ferreira SA, Motwani MS, Faull PA, Seymour AJ, Yu TTL, Enayati M, Taheem DK, Salzlechner C, Haghighi T, Kania EM, Oommen OP, Ahmed T, Loaiza S, Parzych K, Dazzi F, Varghese OP, Festy F, Grigoriadis AE, Auner HW, Snijders AP, Bozec L, Gentleman E.

Nat Commun. 2018 Nov 14;9(1):4851. doi: 10.1038/s41467-018-07398-1.

21.

Enigma proteins regulate YAP mechanotransduction.

Elbediwy A, Vanyai H, Diaz-de-la-Loza MD, Frith D, Snijders AP, Thompson BJ.

J Cell Sci. 2018 Nov 22;131(22). pii: jcs221788. doi: 10.1242/jcs.221788.

22.

SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.

Hirota T, Blakeley P, Sangrithi MN, Mahadevaiah SK, Encheva V, Snijders AP, ElInati E, Ojarikre OA, de Rooij DG, Niakan KK, Turner JMA.

Dev Cell. 2018 Dec 3;47(5):645-659.e6. doi: 10.1016/j.devcel.2018.10.004. Epub 2018 Nov 1.

23.

Bi-directional cell-pericellular matrix interactions direct stem cell fate.

Ferreira SA, Motwani MS, Faull PA, Seymour AJ, Yu TTL, Enayati M, Taheem DK, Salzlechner C, Haghighi T, Kania EM, Oommen OP, Ahmed T, Loaiza S, Parzych K, Dazzi F, Varghese OP, Festy F, Grigoriadis AE, Auner HW, Snijders AP, Bozec L, Gentleman E.

Nat Commun. 2018 Oct 3;9(1):4049. doi: 10.1038/s41467-018-06183-4. Erratum in: Nat Commun. 2018 Nov 14;9(1):4851. Nat Commun. 2018 Dec 18;9(1):5419.

24.

Chemical genetic identification of CDKL5 substrates reveals its role in neuronal microtubule dynamics.

Baltussen LL, Negraes PD, Silvestre M, Claxton S, Moeskops M, Christodoulou E, Flynn HR, Snijders AP, Muotri AR, Ultanir SK.

EMBO J. 2018 Dec 14;37(24). pii: e99763. doi: 10.15252/embj.201899763. Epub 2018 Sep 28.

25.

α-actinin accounts for the bioactivity of actin preparations in inducing STAT target genes in Drosophila melanogaster.

Gordon O, Henry CM, Srinivasan N, Ahrens S, Franz A, Deddouche S, Chakravarty P, Phillips D, George R, Kjaer S, Frith D, Snijders AP, Valente RS, Simoes da Silva CJ, Teixeira L, Thompson B, Dionne MS, Wood W, Reis E Sousa C.

Elife. 2018 Sep 27;7. pii: e38636. doi: 10.7554/eLife.38636.

26.

Author Correction: Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis.

Ferrandiz N, Barroso C, Telecan O, Shao N, Kim HM, Testori S, Faull P, Cutillas P, Snijders AP, Colaiácovo MP, Martinez-Perez E.

Nat Commun. 2018 Aug 29;9(1):3558. doi: 10.1038/s41467-018-05848-4.

27.

Forcing the reversibility of a mechanochemical reaction.

Beedle AEM, Mora M, Davis CT, Snijders AP, Stirnemann G, Garcia-Manyes S.

Nat Commun. 2018 Aug 8;9(1):3155. doi: 10.1038/s41467-018-05115-6.

28.

Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe.

Swaffer MP, Jones AW, Flynn HR, Snijders AP, Nurse P.

Cell Rep. 2018 Jul 10;24(2):503-514. doi: 10.1016/j.celrep.2018.06.036.

29.

Cysteine-Reactive Free ISG15 Generates IL-1β-Producing CD8α+ Dendritic Cells at the Site of Infection.

Napolitano A, van der Veen AG, Bunyan M, Borg A, Frith D, Howell S, Kjaer S, Beling A, Snijders AP, Knobeloch KP, Frickel EM.

J Immunol. 2018 Jul 15;201(2):604-614. doi: 10.4049/jimmunol.1701322. Epub 2018 Jun 11.

30.

Neighboring cells override 3D hydrogel matrix cues to drive human MSC quiescence.

Ferreira SA, Faull PA, Seymour AJ, Yu TTL, Loaiza S, Auner HW, Snijders AP, Gentleman E.

Biomaterials. 2018 Sep;176:13-23. doi: 10.1016/j.biomaterials.2018.05.032. Epub 2018 May 22.

31.

Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis.

Bellelli R, Borel V, Logan C, Svendsen J, Cox DE, Nye E, Metcalfe K, O'Connell SM, Stamp G, Flynn HR, Snijders AP, Lassailly F, Jackson A, Boulton SJ.

Mol Cell. 2018 May 17;70(4):707-721.e7. doi: 10.1016/j.molcel.2018.04.008. Epub 2018 May 10.

32.

Phosphoproteome dynamics during mitotic exit in budding yeast.

Touati SA, Kataria M, Jones AW, Snijders AP, Uhlmann F.

EMBO J. 2018 May 15;37(10). pii: e98745. doi: 10.15252/embj.201798745. Epub 2018 Apr 12.

33.

Publisher Correction: A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.

Thomas JA, Tan MSY, Bisson C, Borg A, Umrekar TR, Hackett F, Hale VL, Vizcay-Barrena G, Fleck RA, Snijders AP, Saibil HR, Blackman MJ.

Nat Microbiol. 2018 Apr;3(4):523. doi: 10.1038/s41564-018-0134-6.

PMID:
29511275
34.

Murine Gbp1 and Gbp2 are ubiquitinated independent of Toxoplasma gondii infection.

Encheva V, Foltz C, Snijders AP, Frickel EM.

BMC Res Notes. 2018 Mar 6;11(1):166. doi: 10.1186/s13104-018-3267-z.

35.

Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis.

Ferrandiz N, Barroso C, Telecan O, Shao N, Kim HM, Testori S, Faull P, Cutillas P, Snijders AP, Colaiácovo MP, Martinez-Perez E.

Nat Commun. 2018 Feb 26;9(1):834. doi: 10.1038/s41467-018-03229-5. Erratum in: Nat Commun. 2018 Aug 29;9(1):3558.

36.

A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.

Thomas JA, Tan MSY, Bisson C, Borg A, Umrekar TR, Hackett F, Hale VL, Vizcay-Barrena G, Fleck RA, Snijders AP, Saibil HR, Blackman MJ.

Nat Microbiol. 2018 Apr;3(4):447-455. doi: 10.1038/s41564-018-0111-0. Epub 2018 Feb 19. Erratum in: Nat Microbiol. 2018 Mar 6;:.

37.

The RIG-I-like receptor LGP2 inhibits Dicer-dependent processing of long double-stranded RNA and blocks RNA interference in mammalian cells.

van der Veen AG, Maillard PV, Schmidt JM, Lee SA, Deddouche-Grass S, Borg A, Kjær S, Snijders AP, Reis e Sousa C.

EMBO J. 2018 Feb 15;37(4). pii: e97479. doi: 10.15252/embj.201797479. Epub 2018 Jan 19.

38.

The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.

Khan OM, Carvalho J, Spencer-Dene B, Mitter R, Frith D, Snijders AP, Wood SA, Behrens A.

J Clin Invest. 2018 Apr 2;128(4):1326-1337. doi: 10.1172/JCI97325. Epub 2018 Feb 26.

39.

Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology.

Vantourout P, Laing A, Woodward MJ, Zlatareva I, Apolonia L, Jones AW, Snijders AP, Malim MH, Hayday AC.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):1039-1044. doi: 10.1073/pnas.1701237115. Epub 2018 Jan 16.

40.

USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.

Stockum A, Snijders AP, Maertens GN.

PLoS One. 2018 Jan 2;13(1):e0190513. doi: 10.1371/journal.pone.0190513. eCollection 2018.

41.

Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA.

Coelho MA, de Carné Trécesson S, Rana S, Zecchin D, Moore C, Molina-Arcas M, East P, Spencer-Dene B, Nye E, Barnouin K, Snijders AP, Lai WS, Blackshear PJ, Downward J.

Immunity. 2017 Dec 19;47(6):1083-1099.e6. doi: 10.1016/j.immuni.2017.11.016. Epub 2017 Dec 12.

42.

Identification of SUMO conjugation sites in the budding yeast proteome.

Esteras M, Liu IC, Snijders AP, Jarmuz A, Aragon L.

Microb Cell. 2017 Oct 2;4(10):331-341. doi: 10.15698/mic2017.10.593.

43.

USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination.

Novellasdemunt L, Foglizzo V, Cuadrado L, Antas P, Kucharska A, Encheva V, Snijders AP, Li VSW.

Cell Rep. 2017 Oct 17;21(3):612-627. doi: 10.1016/j.celrep.2017.09.072.

44.

Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy.

Joachim J, Razi M, Judith D, Wirth M, Calamita E, Encheva V, Dynlacht BD, Snijders AP, O'Reilly N, Jefferies HBJ, Tooze SA.

Curr Biol. 2017 Jul 24;27(14):2123-2136.e7. doi: 10.1016/j.cub.2017.06.021. Epub 2017 Jul 14.

45.

A systematic genomic screen implicates nucleocytoplasmic transport and membrane growth in nuclear size control.

Kume K, Cantwell H, Neumann FR, Jones AW, Snijders AP, Nurse P.

PLoS Genet. 2017 May 18;13(5):e1006767. doi: 10.1371/journal.pgen.1006767. eCollection 2017 May.

46.

Erratum: Structural Basis of Eco1-Mediated Cohesin Acetylation.

Chao WC, Wade BO, Bouchoux C, Jones AW, Purkiss AG, Federico S, O'Reilly N, Snijders AP, Uhlmann F, Singleton MR.

Sci Rep. 2017 Apr 11;7:46382. doi: 10.1038/srep46382. No abstract available.

47.

Structural Basis of Eco1-Mediated Cohesin Acetylation.

Chao WC, Wade BO, Bouchoux C, Jones AW, Purkiss AG, Federico S, O'Reilly N, Snijders AP, Uhlmann F, Singleton MR.

Sci Rep. 2017 Mar 14;7:44313. doi: 10.1038/srep44313. Erratum in: Sci Rep. 2017 Apr 11;7:46382.

48.

Integrin Beta 3 Regulates Cellular Senescence by Activating the TGF-β Pathway.

Rapisarda V, Borghesan M, Miguela V, Encheva V, Snijders AP, Lujambio A, O'Loghlen A.

Cell Rep. 2017 Mar 7;18(10):2480-2493. doi: 10.1016/j.celrep.2017.02.012.

49.

Cyclin D mediates tolerance of genome-doubling in cancers with functional p53.

Crockford A, Zalmas LP, Grönroos E, Dewhurst SM, McGranahan N, Cuomo ME, Encheva V, Snijders AP, Begum J, Purewal S, Cerveira J, Patel H, Renshaw MJ, Swanton C.

Ann Oncol. 2017 Jan 1;28(1):149-156. doi: 10.1093/annonc/mdw612.

50.

PP2ACdc55 Phosphatase Imposes Ordered Cell-Cycle Phosphorylation by Opposing Threonine Phosphorylation.

Godfrey M, Touati SA, Kataria M, Jones A, Snijders AP, Uhlmann F.

Mol Cell. 2017 Feb 2;65(3):393-402.e3. doi: 10.1016/j.molcel.2016.12.018. Epub 2017 Jan 26.

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