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Items: 1 to 50 of 440

1.

Influence of lung donor agonal and warm ischemic times on early mortality: Analyses from the ISHLT DCD Lung Transplant Registry.

Levvey B, Keshavjee S, Cypel M, Robinson A, Erasmus M, Glanville A, Hopkins P, Musk M, Hertz M, McCurry K, Van Raemdonck D, Snell G.

J Heart Lung Transplant. 2018 Aug 11. pii: S1053-2498(18)31598-5. doi: 10.1016/j.healun.2018.08.006. [Epub ahead of print]

PMID:
30297241
2.

A Randomized Study of Quantiferon-CMV-Directed Versus Fixed Duration Valganciclovir Prophylaxis to Reduce Late CMV Following Lung Transplantation.

Westall GP, Cristiano Y, Levvey BJ, Whitford H, Paraskeva MA, Paul E, Peleg AY, Snell GI.

Transplantation. 2018 Sep 21. doi: 10.1097/TP.0000000000002454. [Epub ahead of print]

PMID:
30247316
3.

An Update in Antimicrobial Therapies and Infection Prevention in Pediatric Lung Transplant Recipients.

Smibert OC, Paraskeva MA, Westall G, Snell G.

Paediatr Drugs. 2018 Sep 6. doi: 10.1007/s40272-018-0313-1. [Epub ahead of print] Review.

PMID:
30187362
4.

Cryptococcal infection in lung transplant recipients: A 5-year retrospective review at an Australian transplant center.

Sohail A, Smibert OC, Snell G, Paraskeva M, Jenney A.

Transpl Infect Dis. 2018 Aug 18:e12976. doi: 10.1111/tid.12976. [Epub ahead of print]

PMID:
30120885
5.

The Evolution of Lung Transplant Immunosuppression.

Ivulich S, Westall G, Dooley M, Snell G.

Drugs. 2018 Jul;78(10):965-982. doi: 10.1007/s40265-018-0930-6.

PMID:
29915895
6.

Lung transplantation in Australia, 1986-2018: more than 30 years in the making.

Paraskeva MA, Levin KC, Westall GP, Snell GI.

Med J Aust. 2018 Jun 4;208(10):445-450.

PMID:
29848249
7.

Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.

Iwai K, Yaguchi M, Nishimura K, Yamamoto Y, Tamura T, Nakata D, Dairiki R, Kawakita Y, Mizojiri R, Ito Y, Asano M, Maezaki H, Nakayama Y, Kaishima M, Hayashi K, Teratani M, Miyakawa S, Iwatani M, Miyamoto M, Klein MG, Lane W, Snell G, Tjhen R, He X, Pulukuri S, Nomura T.

EMBO Mol Med. 2018 Jun;10(6). pii: e8289. doi: 10.15252/emmm.201708289.

8.

Discovery of benzimidazole derivatives as orally active renin inhibitors: Optimization of 3,5-disubstituted piperidine to improve pharmacokinetic profile.

Tokuhara H, Imaeda Y, Fukase Y, Iwanaga K, Taya N, Watanabe K, Kanagawa R, Matsuda K, Kajimoto Y, Kusumoto K, Kondo M, Snell G, Behnke CA, Kuroita T.

Bioorg Med Chem. 2018 Jul 23;26(12):3261-3286. doi: 10.1016/j.bmc.2018.04.051. Epub 2018 Apr 27.

PMID:
29754833
9.

Donation after Brain Death versus Donation after Circulatory Death: Lung Donor Management Issues.

Snell GI, Levvey BJ, Levin K, Paraskeva M, Westall G.

Semin Respir Crit Care Med. 2018 Apr;39(2):138-147. doi: 10.1055/s-0037-1615820. Epub 2018 Mar 26.

PMID:
29579767
10.

The timing and extent of acute physiotherapy involvement following lung transplantation: An observational study.

Tarrant BJ, Holland A, Le Maitre C, Robinson R, Corbett M, Bondarenko J, Button B, Thompson B, Snell G.

Physiother Res Int. 2018 Jul;23(3):e1710. doi: 10.1002/pri.1710. Epub 2018 Mar 12.

PMID:
29528538
11.

Donor Lung Procurement by Surgical Fellow With an Expectation of High Rate of Lung Utilisation.

Smail H, Saxena P, Wallinder A, Lin E, Snell GI, Hobson J, Zimmet AD, Marasco SF, McGiffin DC.

Heart Lung Circ. 2018 Aug;27(8):961-966. doi: 10.1016/j.hlc.2017.12.007. Epub 2017 Dec 22. Review.

PMID:
29525135
12.

Discovery of [ cis-3-({(5 R)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1 H-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5 H)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist.

Kono M, Ochida A, Oda T, Imada T, Banno Y, Taya N, Masada S, Kawamoto T, Yonemori K, Nara Y, Fukase Y, Yukawa T, Tokuhara H, Skene R, Sang BC, Hoffman ID, Snell GP, Uga K, Shibata A, Igaki K, Nakamura Y, Nakagawa H, Tsuchimori N, Yamasaki M, Shirai J, Yamamoto S.

J Med Chem. 2018 Apr 12;61(7):2973-2988. doi: 10.1021/acs.jmedchem.8b00061. Epub 2018 Mar 14.

PMID:
29510038
13.

Reliability of sternal instability scale (SIS) for transverse sternotomy in lung transplantation (LTX).

Fuller LM, El-Ansary D, Button B, Bondarenko J, Marasco S, Snell G, Holland AE.

Physiother Theory Pract. 2018 Jan 25:1-4. doi: 10.1080/09593985.2018.1431342. [Epub ahead of print]

PMID:
29369002
14.

A successful aggressive surgical and medical approach to pulmonary artery obstruction due to Mycobacterium abscessus infection post lung transplantation.

Kotecha S, Smibert OC, Doi A, Gooi J, Morrissey O, Paraskeva M, Snell GI, McGiffin D.

Transpl Infect Dis. 2018 Apr;20(2):e12838. doi: 10.1111/tid.12838. Epub 2018 Feb 19.

PMID:
29359876
15.

Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors.

Kaieda A, Takahashi M, Takai T, Goto M, Miyazaki T, Hori Y, Unno S, Kawamoto T, Tanaka T, Itono S, Takagi T, Hamada T, Shirasaki M, Okada K, Snell G, Bragstad K, Sang BC, Uchikawa O, Miwatashi S.

Bioorg Med Chem. 2018 Feb 1;26(3):647-660. doi: 10.1016/j.bmc.2017.12.031. Epub 2017 Dec 24.

PMID:
29291937
16.

Single-centre study of therapeutic drug monitoring of posaconazole in lung transplant recipients: factors affecting trough plasma concentrations.

Jeong W, Snell GI, Levvey BJ, Westall GP, Morrissey CO, Wolfe R, Ivulich S, Neoh CF, Slavin MA, Kong DCM.

J Antimicrob Chemother. 2017 Dec 2. doi: 10.1093/jac/dkx440. [Epub ahead of print]

PMID:
29211913
17.

Clinical Challenges of Tacrolimus for Maintenance Immunosuppression Post-Lung Transplantation.

Ivulich S, Dooley M, Kirkpatrick C, Snell G.

Transplant Proc. 2017 Nov;49(9):2153-2160. doi: 10.1016/j.transproceed.2017.07.013. Review.

PMID:
29149976
18.

Identification of the Gender-Specific Health Needs of Women Following Lung Transplantation.

Robertson EE, Bell RJ, Robinson PJ, Snell G, Levvey B, Whitford HM, Harris J, Davis SR.

J Womens Health (Larchmt). 2018 Apr;27(4):485-491. doi: 10.1089/jwh.2017.6627. Epub 2017 Nov 7.

PMID:
29111860
19.

Physical Function in Subjects Requiring Extracorporeal Membrane Oxygenation Before or After Lung Transplantation.

Hayes K, Hodgson CL, Pellegrino VA, Snell G, Tarrant B, Fuller LM, Holland AE.

Respir Care. 2018 Feb;63(2):194-202. doi: 10.4187/respcare.05334. Epub 2017 Oct 31.

PMID:
29089461
20.

Donor-Derived Mycoplasma hominis and an Apparent Cluster of M. hominis Cases in Solid Organ Transplant Recipients.

Smibert OC, Wilson HL, Sohail A, Narayanasamy S, Schultz MB, Ballard SA, Kwong JC, de Boer J, Morrissey CO, Peleg AY, Snell GI, Paraskeva MA, Jenney AWJ.

Clin Infect Dis. 2017 Oct 16;65(9):1504-1508. doi: 10.1093/cid/cix601.

PMID:
29048510
21.

Effect of Upper Limb Rehabilitation Compared to No Upper Limb Rehabilitation in Lung Transplant Recipients: A Randomized Controlled Trial.

Fuller LM, El-Ansary D, Button BM, Corbett M, Snell G, Marasco S, Holland AE.

Arch Phys Med Rehabil. 2018 Jul;99(7):1257-1264.e2. doi: 10.1016/j.apmr.2017.09.115. Epub 2017 Oct 16.

PMID:
29042172
22.

Continued Successful Evolution of Extended Criteria Donor Lungs for Transplantation.

Kotecha S, Hobson J, Fuller J, Paul E, Levvey BJ, Whitford H, Paraskeva M, McGiffin D, Snell GI, Westall GP.

Ann Thorac Surg. 2017 Nov;104(5):1702-1709. doi: 10.1016/j.athoracsur.2017.05.042. Epub 2017 Sep 28.

PMID:
28964417
23.

Untapped potential in Australian hospitals for organ donation after circulatory death.

Rakhra SS, Opdam HI, Gladkis L, Arcia B, Fink MA, Kanellis J, Macdonald PS, Snell GI, Pilcher DV.

Med J Aust. 2017 Sep 2;207(7):294-301.

PMID:
28954604
24.

Report of the ISHLT Working Group on Primary Lung Graft Dysfunction, part I: Definition and grading-A 2016 Consensus Group statement of the International Society for Heart and Lung Transplantation.

Snell GI, Yusen RD, Weill D, Strueber M, Garrity E, Reed A, Pelaez A, Whelan TP, Perch M, Bag R, Budev M, Corris PA, Crespo MM, Witt C, Cantu E, Christie JD.

J Heart Lung Transplant. 2017 Oct;36(10):1097-1103. doi: 10.1016/j.healun.2017.07.021. Epub 2017 Jul 26. No abstract available.

PMID:
28942784
25.

Domiciliary non-invasive ventilation post lung transplantation.

Kotecha S, Buchan C, Parker K, Toghill J, Paul E, Miller B, Naughton M, Snell G, Dabscheck E.

Respirology. 2018 Jan;23(1):96-99. doi: 10.1111/resp.13160. Epub 2017 Aug 24.

PMID:
28840631
26.

Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug design.

Yasui T, Yamamoto T, Sakai N, Asano K, Takai T, Yoshitomi Y, Davis M, Takagi T, Sakamoto K, Sogabe S, Kamada Y, Lane W, Snell G, Iwata M, Goto M, Inooka H, Sakamoto JI, Nakada Y, Imaeda Y.

Bioorg Med Chem. 2017 Sep 1;25(17):4876-4886. doi: 10.1016/j.bmc.2017.07.037. Epub 2017 Jul 20.

PMID:
28760529
27.

The evolution of lung transplantation for cystic fibrosis: A 2017 update.

Snell G, Reed A, Stern M, Hadjiliadis D.

J Cyst Fibros. 2017 Sep;16(5):553-564. doi: 10.1016/j.jcf.2017.06.008. Epub 2017 Jul 12. Review.

PMID:
28711221
28.

Activin Biology After Lung Transplantation.

Westall GP, Snell GI, Loskot M, Levvey B, O'Hehir R, Hedger MP, de Kretser DM.

Transplant Direct. 2017 May 11;3(6):e159. doi: 10.1097/TXD.0000000000000676. eCollection 2017 Jun.

29.

Discovery of a B-Cell Lymphoma 6 Protein-Protein Interaction Inhibitor by a Biophysics-Driven Fragment-Based Approach.

Kamada Y, Sakai N, Sogabe S, Ida K, Oki H, Sakamoto K, Lane W, Snell G, Iida M, Imaeda Y, Sakamoto J, Matsui J.

J Med Chem. 2017 May 25;60(10):4358-4368. doi: 10.1021/acs.jmedchem.7b00313. Epub 2017 May 11.

PMID:
28471657
30.

Clinical effectiveness of early posaconazole suspension pre-emptive therapy in lung transplant recipients: The Alfred's experience.

Jeong W, Snell GI, Levvey BJ, Westall GP, Morrissey CO, Ivulich S, Neoh CF, Slavin MA, Kong DCM.

J Antimicrob Chemother. 2017 Jul 1;72(7):2089-2092. doi: 10.1093/jac/dkx085.

PMID:
28369489
31.

Outcomes of adolescent recipients after lung transplantation: An analysis of the International Society for Heart and Lung Transplantation Registry.

Paraskeva MA, Edwards LB, Levvey B, Stehlik J, Goldfarb S, Yusen RD, Westall GP, Snell GI.

J Heart Lung Transplant. 2018 Mar;37(3):323-331. doi: 10.1016/j.healun.2017.02.017. Epub 2017 Feb 17.

PMID:
28320631
32.

Sequential unilateral lung volume reduction for emphysema - Stretching the benefit.

Khorramnia S, Holsworth L, Mestitz H, Westall GP, Williams TJ, Gooi JH, Snell GI.

Respir Med Case Rep. 2017 Jan 6;20:120-122. doi: 10.1016/j.rmcr.2017.01.002. eCollection 2017.

33.

Feasibility and Safety of a Transthoracic Pneumostoma Airway Bypass in Severe Emphysema Patients.

Snell GI, Holsworth L, Khorramnia S, Westall GP, Williams TJ, Marasco S, Gooi JH.

Respiration. 2017;93(4):236-246. doi: 10.1159/000455878. Epub 2017 Feb 1.

34.

Predictive performance of different kidney function estimation equations in lung transplant patients.

Degen DA, Janardan J, Barraclough KA, Schneider HG, Barber T, Barton H, Snell G, Levvey B, Walker RG.

Clin Biochem. 2017 May;50(7-8):385-393. doi: 10.1016/j.clinbiochem.2017.01.008. Epub 2017 Jan 17.

PMID:
28108166
35.

Poor Glycemic Control Is Associated With Decreased Survival in Lung Transplant Recipients.

Hackman KL, Snell GI, Bach LA.

Transplantation. 2017 Sep;101(9):2200-2206. doi: 10.1097/TP.0000000000001555.

PMID:
27798516
36.

Novel approach of fragment-based lead discovery applied to renin inhibitors.

Tawada M, Suzuki S, Imaeda Y, Oki H, Snell G, Behnke CA, Kondo M, Tarui N, Tanaka T, Kuroita T, Tomimoto M.

Bioorg Med Chem. 2016 Nov 15;24(22):6066-6074. doi: 10.1016/j.bmc.2016.09.065. Epub 2016 Sep 28.

PMID:
27720325
37.

Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors.

Imaeda Y, Tawada M, Suzuki S, Tomimoto M, Kondo M, Tarui N, Sanada T, Kanagawa R, Snell G, Behnke CA, Kubo K, Kuroita T.

Bioorg Med Chem. 2016 Nov 15;24(22):5771-5780. doi: 10.1016/j.bmc.2016.09.030. Epub 2016 Sep 13.

38.

Discovery of TAK-272: A Novel, Potent, and Orally Active Renin Inhibitor.

Imaeda Y, Tokuhara H, Fukase Y, Kanagawa R, Kajimoto Y, Kusumoto K, Kondo M, Snell G, Behnke CA, Kuroita T.

ACS Med Chem Lett. 2016 Sep 12;7(10):933-938. eCollection 2016 Oct 13.

39.

Longer Versus Shorter Duration of Supervised Rehabilitation After Lung Transplantation: A Randomized Trial.

Fuller LM, Button B, Tarrant B, Steward R, Bennett L, Snell G, Holland AE.

Arch Phys Med Rehabil. 2017 Feb;98(2):220-226.e3. doi: 10.1016/j.apmr.2016.09.113. Epub 2016 Sep 30.

PMID:
27697429
40.

ABO incompatible renal transplantation following lung transplantation.

Snell GI, Davis AK, Menahem S, Kotecha S, Whitford HM, Levvey BJ, Paraskeva M, Webb A, Westall GW, Walker RG.

Transpl Immunol. 2016 Nov;39:30-33. doi: 10.1016/j.trim.2016.09.002. Epub 2016 Sep 20.

PMID:
27663090
41.

How can we improve the quality of transplantable lungs?

Levin K, Kotecha S, Westall G, Snell G.

Expert Rev Respir Med. 2016 Oct 3:1-7. [Epub ahead of print]

PMID:
27656957
42.

Invasive Scedosporium sternal osteomyelitis following lung transplant: Cured.

Denton EJ, Smibert O, Gooi J, Morrissey CO, Snell G, McGiffin D, Paraskeva M.

Med Mycol Case Rep. 2016 Jul 9;12:14-6. doi: 10.1016/j.mmcr.2016.07.001. eCollection 2016 Jun.

43.

Refractory Pulmonary Edema Caused by Late Pulmonary Vein Thrombosis After Lung Transplantation: A Rare Adverse Event.

Denton EJ, Rischin A, McGiffin D, Williams TJ, Paraskeva MA, Westall GP, Snell G.

Ann Thorac Surg. 2016 Sep;102(3):e197-e199. doi: 10.1016/j.athoracsur.2016.01.090.

PMID:
27549541
44.

Thermal vapour ablation to reduce segmental volume in patients with severe emphysema: STEP-UP 12 month results.

Shah PL, Gompelmann D, Valipour A, McNulty WH, Eberhardt R, Grah C, Egan J, Ficker JH, Wagner M, Witt C, Liebers U, Hopkins P, Gesierich W, Phillips M, Stanzel F, Petermann C, Strange C, Snell G, Herth FJF.

Lancet Respir Med. 2016 Sep;4(9):e44-e45. doi: 10.1016/S2213-2600(16)30199-0. Epub 2016 Jul 20. No abstract available.

PMID:
27451345
45.

Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition.

Wang H, Klein MG, Snell G, Lane W, Zou H, Levin I, Li K, Sang BC.

J Mol Biol. 2016 Jul 3;428(13):2769-79. doi: 10.1016/j.jmb.2016.05.012. Epub 2016 May 21.

PMID:
27220631
46.

Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKCθ inhibitors.

Katoh T, Takai T, Yukawa T, Tsukamoto T, Watanabe E, Mototani H, Arita T, Hayashi H, Nakagawa H, Klein MG, Zou H, Sang BC, Snell G, Nakada Y.

Bioorg Med Chem. 2016 Jun 1;24(11):2466-75. doi: 10.1016/j.bmc.2016.04.008. Epub 2016 Apr 4.

PMID:
27117263
47.

HLA Matching at the Eplet Level Protects Against Chronic Lung Allograft Dysfunction.

Walton DC, Hiho SJ, Cantwell LS, Diviney MB, Wright ST, Snell GI, Paraskeva MA, Westall GP.

Am J Transplant. 2016 Sep;16(9):2695-703. doi: 10.1111/ajt.13798. Epub 2016 Apr 21.

48.

Segmental volume reduction using thermal vapour ablation in patients with severe emphysema: 6-month results of the multicentre, parallel-group, open-label, randomised controlled STEP-UP trial.

Herth FJ, Valipour A, Shah PL, Eberhardt R, Grah C, Egan J, Ficker JH, Wagner M, Witt C, Liebers U, Hopkins P, Gesierich W, Phillips M, Stanzel F, McNulty WH, Petermann C, Snell G, Gompelmann D.

Lancet Respir Med. 2016 Mar;4(3):185-93. doi: 10.1016/S2213-2600(16)00045-X. Epub 2016 Feb 16.

PMID:
26899390
49.

Substantial Increases Occur in Serum Activins and Follistatin during Lung Transplantation.

de Kretser DM, Bensley JG, Phillips DJ, Levvey BJ, Snell GI, Lin E, Hedger MP, O'Hehir RE.

PLoS One. 2016 Jan 28;11(1):e0140948. doi: 10.1371/journal.pone.0140948. eCollection 2016.

50.

Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases.

Li P, Zheng H, Zhao J, Zhang L, Yao W, Zhu H, Beard JD, Ida K, Lane W, Snell G, Sogabe S, Heyser CJ, Snyder GL, Hendrick JP, Vanover KE, Davis RE, Wennogle LP.

J Med Chem. 2016 Feb 11;59(3):1149-64. doi: 10.1021/acs.jmedchem.5b01751. Epub 2016 Feb 2.

PMID:
26789933

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