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Items: 7


Dog UDP-glucuronosyltransferase enzymes of subfamily 1A: cloning, expression, and activity.

Troberg J, Järvinen E, Muniz M, Sneitz N, Mosorin J, Hagström M, Finel M.

Drug Metab Dispos. 2015 Jan;43(1):107-18. doi: 10.1124/dmd.114.059303. Epub 2014 Oct 9.


Regiospecificity and stereospecificity of human UDP-glucuronosyltransferases in the glucuronidation of estriol, 16-epiestriol, 17-epiestriol, and 13-epiestradiol.

Sneitz N, Vahermo M, Mosorin J, Laakkonen L, Poirier D, Finel M.

Drug Metab Dispos. 2013 Mar;41(3):582-91. doi: 10.1124/dmd.112.049072. Epub 2013 Jan 3.


Ezetimibe: A biomarker for efficacy of liver directed UGT1A1 gene therapy for inherited hyperbilirubinemia.

Montenegro-Miranda PS, Sneitz N, de Waart DR, Ten Bloemendaal L, Duijst S, de Knegt RJ, Beuers U, Finel M, Bosma PJ.

Biochim Biophys Acta. 2012 Aug;1822(8):1223-9. doi: 10.1016/j.bbadis.2012.04.013. Epub 2012 Apr 21.


Glucuronidation of the steroid enantiomers ent-17β-estradiol, ent-androsterone and ent-etiocholanolone by the human UDP-glucuronosyltransferases.

Sneitz N, Krishnan K, Covey DF, Finel M.

J Steroid Biochem Mol Biol. 2011 Nov;127(3-5):282-8. doi: 10.1016/j.jsbmb.2011.08.008. Epub 2011 Aug 27.


Phenylalanine 93 of the human UGT1A10 plays a major role in the interactions of the enzyme with estrogens.

Höglund C, Sneitz N, Radominska-Pandya A, Laakonen L, Finel M.

Steroids. 2011 Dec 11;76(13):1465-73. doi: 10.1016/j.steroids.2011.07.017. Epub 2011 Aug 9.


Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3.

Sneitz N, Court MH, Zhang X, Laajanen K, Yee KK, Dalton P, Ding X, Finel M.

Pharmacogenet Genomics. 2009 Dec;19(12):923-34. doi: 10.1097/FPC.0b013e3283330767.


Crigler-Najjar syndrome in The Netherlands: identification of four novel UGT1A1 alleles, genotype-phenotype correlation, and functional analysis of 10 missense mutants.

Sneitz N, Bakker CT, de Knegt RJ, Halley DJ, Finel M, Bosma PJ.

Hum Mutat. 2010 Jan;31(1):52-9. doi: 10.1002/humu.21133.


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