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Items: 1 to 50 of 152

1.

Using Nanoscopy To Probe the Biological Activity of Antimicrobial Leads That Display Potent Activity against Pathogenic, Multidrug Resistant, Gram-Negative Bacteria.

Smitten KL, Southam HM, de la Serna JB, Gill MR, Jarman PJ, Smythe CGW, Poole RK, Thomas JA.

ACS Nano. 2019 May 28;13(5):5133-5146. doi: 10.1021/acsnano.8b08440. Epub 2019 Apr 9.

PMID:
30964642
2.

Exploring the Cytotoxicity, Uptake, Cellular Response, and Proteomics of Mono- and Dinuclear DNA Light-Switch Complexes.

Jarman PJ, Noakes F, Fairbanks S, Smitten K, Griffiths IK, Saeed HK, Thomas JA, Smythe C.

J Am Chem Soc. 2019 Feb 20;141(7):2925-2937. doi: 10.1021/jacs.8b09999. Epub 2019 Feb 7.

PMID:
30595016
3.

Two photon excitable graphene quantum dots for structured illumination microscopy and imaging applications: lysosome specificity and tissue-dependent imaging.

Singh H, Sreedharan S, Tiwari K, Green NH, Smythe C, Pramanik SK, Thomas JA, Das A.

Chem Commun (Camb). 2019 Jan 3;55(4):521-524. doi: 10.1039/c8cc08610a.

PMID:
30556083
4.

l-Quebrachitol Promotes the Proliferation, Differentiation, and Mineralization of MC3T3-E1 Cells: Involvement of the BMP-2/Runx2/MAPK/Wnt/β-Catenin Signaling Pathway.

Yodthong T, Kedjarune-Leggat U, Smythe C, Wititsuwannakul R, Pitakpornpreecha T.

Molecules. 2018 Nov 26;23(12). pii: E3086. doi: 10.3390/molecules23123086.

5.

Mitochondria Targeting Non-Isocyanate-Based Polyurethane Nanocapsules for Enzyme-Triggered Drug Release.

Pramanik SK, Sreedharan S, Singh H, Khan M, Tiwari K, Shiras A, Smythe C, Thomas JA, Das A.

Bioconjug Chem. 2018 Nov 21;29(11):3532-3543. doi: 10.1021/acs.bioconjchem.8b00460. Epub 2018 Aug 6.

6.

A three-in-one-bullet for oesophageal cancer: replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium(ii) metallo-intercalator.

Gill MR, Jarman PJ, Halder S, Walker MG, Saeed HK, Thomas JA, Smythe C, Ramadan K, Vallis KA.

Chem Sci. 2017 Nov 16;9(4):841-849. doi: 10.1039/c7sc03712k. eCollection 2018 Jan 28.

7.

Polysulfide-triggered fluorescent indicator suitable for super-resolution microscopy and application in imaging.

A AH, Sreedharan S, Ali F, Smythe CG, Thomas JA, Das A.

Chem Commun (Camb). 2018 Apr 10;54(30):3735-3738. doi: 10.1039/c8cc01332b.

8.

Mitochondria-localising DNA-binding biscyclometalated phenyltriazole iridium(iii) dipyridophenazene complexes: syntheses and cellular imaging properties.

Sreedharan S, Sinopoli A, Jarman PJ, Robinson D, Clemmet C, Scattergood PA, Rice CR, Smythe CGW, Thomas JA, Elliott PIP.

Dalton Trans. 2018 Apr 3;47(14):4931-4940. doi: 10.1039/C8DT00046H.

9.

Tracking HOCl concentrations across cellular organelles in real time using a super resolution microscopy probe.

Ali F, Aute S, Sreedharan S, Anila HA, Saeed HK, Smythe CG, Thomas JA, Das A.

Chem Commun (Camb). 2018 Feb 15;54(15):1849-1852. doi: 10.1039/c7cc09433g.

10.

Imaging cellular trafficking processes in real time using lysosome targeted up-conversion nanoparticles.

Pramanik SK, Sreedharan S, Singh H, Green NH, Smythe C, Thomas JA, Das A.

Chem Commun (Camb). 2017 Nov 23;53(94):12672-12675. doi: 10.1039/c7cc08185e.

11.

A Super-Resolution Probe To Monitor HNO Levels in the Endoplasmic Reticulum of Cells.

Ali F, Sreedharan S, Ashoka AH, Saeed HK, Smythe CGW, Thomas JA, Das A.

Anal Chem. 2017 Nov 21;89(22):12087-12093. doi: 10.1021/acs.analchem.7b02567. Epub 2017 Nov 7.

12.

Multimodal Super-resolution Optical Microscopy Using a Transition-Metal-Based Probe Provides Unprecedented Capabilities for Imaging Both Nuclear Chromatin and Mitochondria.

Sreedharan S, Gill MR, Garcia E, Saeed HK, Robinson D, Byrne A, Cadby A, Keyes TE, Smythe C, Pellett P, Bernardino de la Serna J, Thomas JA.

J Am Chem Soc. 2017 Nov 8;139(44):15907-15913. doi: 10.1021/jacs.7b08772. Epub 2017 Oct 26.

13.

Homo- and Heteroleptic Phototoxic Dinuclear Metallo-Intercalators Based on RuII (dppn) Intercalating Moieties: Synthesis, Optical, and Biological Studies.

Saeed HK, Jarman PJ, Archer S, Sreedharan S, Saeed IQ, Mckenzie LK, Weinstein JA, Buurma NJ, Smythe CGW, Thomas JA.

Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12628-12633. doi: 10.1002/anie.201707350. Epub 2017 Sep 7.

14.

A Self-Assembled Metallomacrocycle Singlet Oxygen Sensitizer for Photodynamic Therapy.

Walker MG, Jarman PJ, Gill MR, Tian X, Ahmad H, Reddy PA, McKenzie L, Weinstein JA, Meijer AJ, Battaglia G, Smythe CG, Thomas JA.

Chemistry. 2016 Apr 18;22(17):5996-6000. doi: 10.1002/chem.201600852. Epub 2016 Mar 22.

15.

Synthesis and activity of a novel inhibitor of nonsense-mediated mRNA decay.

Gotham VJ, Hobbs MC, Burgin R, Turton D, Smythe C, Coldham I.

Org Biomol Chem. 2016 Feb 7;14(5):1559-63. doi: 10.1039/c5ob02482j.

16.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M.

Semin Cancer Biol. 2015 Dec;35 Suppl:S276-S304. doi: 10.1016/j.semcancer.2015.09.007. Review.

17.

klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes.

Novodvorsky P, Watson O, Gray C, Wilkinson RN, Reeve S, Smythe C, Beniston R, Plant K, Maguire R, M K Rothman A, Elworthy S, van Eeden FJ, Chico TJ.

PLoS One. 2015 Oct 27;10(10):e0141611. doi: 10.1371/journal.pone.0141611. eCollection 2015.

18.

Serum Albumin Binding Inhibits Nuclear Uptake of Luminescent Metal-Complex-Based DNA Imaging Probes.

Wragg A, Gill MR, McKenzie L, Glover C, Mowll R, Weinstein JA, Su X, Smythe C, Thomas JA.

Chemistry. 2015 Aug 10;21(33):11865-71. doi: 10.1002/chem.201501675. Epub 2015 Jul 1.

PMID:
26133680
19.

A Cytostatic Ruthenium(II)-Platinum(II) Bis(terpyridyl) Anticancer Complex That Blocks Entry into S Phase by Up-regulating p27(KIP1).

Ramu V, Gill MR, Jarman PJ, Turton D, Thomas JA, Das A, Smythe C.

Chemistry. 2015 Jun 15;21(25):9185-97. doi: 10.1002/chem.201500561. Epub 2015 May 7.

21.

Tuning the cellular uptake properties of luminescent heterobimetallic iridium(III)-ruthenium(II) DNA imaging probes.

Wragg A, Gill MR, Turton D, Adams H, Roseveare TM, Smythe C, Su X, Thomas JA.

Chemistry. 2014 Oct 20;20(43):14004-11. doi: 10.1002/chem.201403693. Epub 2014 Sep 10.

PMID:
25208528
22.

Dinuclear osmium(II) probes for high-resolution visualisation of cellular DNA structure using electron microscopy.

Wragg A, Gill MR, Hill CJ, Su X, Meijer AJ, Smythe C, Thomas JA.

Chem Commun (Camb). 2014 Dec 4;50(93):14494-7. doi: 10.1039/c4cc05547k.

PMID:
25198113
23.

The role of the donor liaison officer at PlusLife (Perth Bone and Tissue Bank Inc.), Western Australia.

Smythe C, White N, Winter J, Cowie A.

Cell Tissue Bank. 2015 Jun;16(2):303-9. doi: 10.1007/s10561-014-9464-7. Epub 2014 Aug 1.

PMID:
25080848
24.

Dinuclear ruthenium(II) complexes as two-photon, time-resolved emission microscopy probes for cellular DNA.

Baggaley E, Gill MR, Green NH, Turton D, Sazanovich IV, Botchway SW, Smythe C, Haycock JW, Weinstein JA, Thomas JA.

Angew Chem Int Ed Engl. 2014 Mar 24;53(13):3367-71. doi: 10.1002/anie.201309427. Epub 2014 Jan 23.

25.

Ruthenium(II) metallo-intercalators: DNA imaging and cytotoxicity.

Gill MR, Derrat H, Smythe CG, Battaglia G, Thomas JA.

Chembiochem. 2011 Apr 11;12(6):877-80. doi: 10.1002/cbic.201000782. Epub 2011 Mar 23. No abstract available.

PMID:
21433240
26.

Hyphal growth in Candida albicans requires the phosphorylation of Sec2 by the Cdc28-Ccn1/Hgc1 kinase.

Bishop A, Lane R, Beniston R, Chapa-y-Lazo B, Smythe C, Sudbery P.

EMBO J. 2010 Sep 1;29(17):2930-42. doi: 10.1038/emboj.2010.158. Epub 2010 Jul 16.

27.

A ruthenium(II) polypyridyl complex for direct imaging of DNA structure in living cells.

Gill MR, Garcia-Lara J, Foster SJ, Smythe C, Battaglia G, Thomas JA.

Nat Chem. 2009 Nov;1(8):662-7. doi: 10.1038/nchem.406. Epub 2009 Oct 18.

PMID:
21378959
28.

NEP-A and NEP-B both contribute to nuclear pore formation in Xenopus eggs and oocytes.

Salpingidou G, Rzepecki R, Kiseleva E, Lyon C, Lane B, Fusiek K, Golebiewska A, Drummond S, Allen T, Ellis JA, Smythe C, Goldberg MW, Hutchison CJ.

J Cell Sci. 2008 Mar 1;121(Pt 5):706-16. doi: 10.1242/jcs.019968. Epub 2008 Feb 12.

29.

DNA-activated protein kinase functions in a newly observed S phase checkpoint that links histone mRNA abundance with DNA replication.

Müller B, Blackburn J, Feijoo C, Zhao X, Smythe C.

J Cell Biol. 2007 Dec 31;179(7):1385-98. Epub 2007 Dec 24. Erratum in: J Cell Biol. 2008 Feb 25;180(4):843.

30.

Are multiple checkpoint mediators involved in a checkpoint linking histone gene expression with DNA replication?

Müller B, Blackburn J, Feijoo C, Zhao X, Smythe C.

Biochem Soc Trans. 2007 Nov;35(Pt 5):1369-71. Review.

PMID:
17956353
31.

Postoperative pain following coblation tonsillectomy: randomized clinical trial.

Polites N, Joniau S, Wabnitz D, Fassina R, Smythe C, Varley P, Carney AS.

ANZ J Surg. 2006 Apr;76(4):226-9.

PMID:
16681537
32.

Proinflammatory activation of macrophages by basic calcium phosphate crystals via protein kinase C and MAP kinase pathways: a vicious cycle of inflammation and arterial calcification?

Nadra I, Mason JC, Philippidis P, Florey O, Smythe CD, McCarthy GM, Landis RC, Haskard DO.

Circ Res. 2005 Jun 24;96(12):1248-56. Epub 2005 May 19.

PMID:
15905460
33.

ATM is required for the cellular response to thymidine induced replication fork stress.

Bolderson E, Scorah J, Helleday T, Smythe C, Meuth M.

Hum Mol Genet. 2004 Dec 1;13(23):2937-45. Epub 2004 Sep 30.

PMID:
15459181
34.

The state of macrophage differentiation determines the TNF alpha response to nitrated lipoprotein uptake.

Smythe CD, Skinner VO, Bruckdorfer KR, Haskard DO, Landis RC.

Atherosclerosis. 2003 Oct;170(2):213-21.

PMID:
14612200
35.

Clathrin promotes incorporation of cargo into coated pits by activation of the AP2 adaptor micro2 kinase.

Jackson AP, Flett A, Smythe C, Hufton L, Wettey FR, Smythe E.

J Cell Biol. 2003 Oct 27;163(2):231-6.

36.

Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.

Sapkota GP, Deak M, Kieloch A, Morrice N, Goodarzi AA, Smythe C, Shiloh Y, Lees-Miller SP, Alessi DR.

Biochem J. 2002 Dec 1;368(Pt 2):507-16.

37.

Purification and identification of secernin, a novel cytosolic protein that regulates exocytosis in mast cells.

Way G, Morrice N, Smythe C, O'Sullivan AJ.

Mol Biol Cell. 2002 Sep;13(9):3344-54.

38.

The role of mitotic vesicles in the nuclear assembly.

Rzepecki R, Smythe C, Hutchison CJ.

Cell Mol Biol Lett. 2002;7(2):299. No abstract available.

PMID:
12097969
39.

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing.

Feijoo C, Hall-Jackson C, Wu R, Jenkins D, Leitch J, Gilbert DM, Smythe C.

J Cell Biol. 2001 Sep 3;154(5):913-23.

40.

INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow.

Adams RR, Wheatley SP, Gouldsworthy AM, Kandels-Lewis SE, Carmena M, Smythe C, Gerloff DL, Earnshaw WC.

Curr Biol. 2000 Sep 7;10(17):1075-8.

41.

Noninflammatory phagocytosis of monosodium urate monohydrate crystals by mouse macrophages. Implications for the control of joint inflammation in gout.

Yagnik DR, Hillyer P, Marshall D, Smythe CD, Krausz T, Haskard DO, Landis RC.

Arthritis Rheum. 2000 Aug;43(8):1779-89.

43.
44.

Information and communication systems for the assistance of carers based on ACTION.

Kraner M, Emery D, Cvetkovic SR, Procter P, Smythe C.

Med Inform Internet Med. 1999 Oct-Dec;24(4):233-48.

PMID:
10674415
45.

ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK.

Hall-Jackson CA, Cross DA, Morrice N, Smythe C.

Oncogene. 1999 Nov 18;18(48):6707-13.

46.
49.

Acute epididymo-orchitis due to Pseudomonas aeruginosa.

Papadakis KA, Sriram PM, Smythe CM.

Eur J Clin Microbiol Infect Dis. 1997 Jun;16(6):476-7. No abstract available.

PMID:
9248756
50.

Some lessons learned in the care of the elderly.

Smythe CM.

Epilepsia. 1997;38 Suppl 4:S50-4. Review.

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