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Items: 23


Genetic Susceptibility to Chronic Kidney Disease - Some More Pieces for the Heritability Puzzle.

Cañadas-Garre M, Anderson K, Cappa R, Skelly R, Smyth LJ, McKnight AJ, Maxwell AP.

Front Genet. 2019 May 31;10:453. doi: 10.3389/fgene.2019.00453. eCollection 2019. Review.


Genetic associations between genes in the renin-angiotensin-aldosterone system and renal disease: a systematic review and meta-analysis.

Smyth LJ, Cañadas-Garre M, Cappa RC, Maxwell AP, McKnight AJ.

BMJ Open. 2019 May 1;9(4):e026777. doi: 10.1136/bmjopen-2018-026777.


The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population.

Stapleton CP, Heinzel A, Guan W, van der Most PJ, van Setten J, Lord GM, Keating BJ, Israni AK, de Borst MH, Bakker SJL, Snieder H, Weale ME, Delaney F, Hernandez-Fuentes MP, Reindl-Schwaighofer R, Oberbauer R, Jacobson PA, Mark PB, Chapman FA, Phelan PJ, Kennedy C, Sexton D, Murray S, Jardine A, Traynor JP, McKnight AJ, Maxwell AP, Smyth LJ, Oetting WS, Matas AJ, Mannon RB, Schladt DP, Iklé DN, Cavalleri GL, Conlon PJ; UK Ireland Renal Transplant Consortium; DeKAF Genomics and GEN03 Studies; International Genetics and Translational Research in Transplantation Network.

Am J Transplant. 2019 Feb 27. doi: 10.1111/ajt.15326. [Epub ahead of print]


Validation of differentially methylated microRNAs identified from an epigenome-wide association study; Sanger and next generation sequencing approaches.

Smyth LJ, Maxwell AP, Benson KA, Kilner J, McKay GJ, McKnight AJ.

BMC Res Notes. 2018 Oct 29;11(1):767. doi: 10.1186/s13104-018-3872-x.


Information on Genetic Variants Does Not Increase Identification of Individuals at Risk of Esophageal Adenocarcinoma Compared to Clinical Risk Factors.

Kunzmann AT, Cañadas Garre M, Thrift AP, McMenamin ÚC, Johnston BT, Cardwell CR, Anderson LA, Spence AD, Lagergren J, Xie SH, Smyth LJ, McKnight AJ, Coleman HG.

Gastroenterology. 2019 Jan;156(1):43-45. doi: 10.1053/j.gastro.2018.09.038. Epub 2018 Sep 19.


Design and implementation of a custom next generation sequencing panel for selected vitamin D associated genes.

Benson KA, Chand S, Maxwell AP, Smyth LJ, Kilner J, Borrows R, McKnight AJ.

BMC Res Notes. 2017 Jul 28;10(1):348. doi: 10.1186/s13104-017-2664-z.


The effects of corticosteroids on cytokine production from asthma lung lymphocytes.

Kaur M, Reynolds S, Smyth LJ, Simpson K, Hall S, Singh D.

Int Immunopharmacol. 2014 Dec;23(2):581-4.


Genetic and epigenetic factors influencing chronic kidney disease.

Smyth LJ, Duffy S, Maxwell AP, McKnight AJ.

Am J Physiol Renal Physiol. 2014 Oct 1;307(7):F757-76. doi: 10.1152/ajprenal.00306.2014. Epub 2014 Jul 30. Review.


c-Met inhibition in a HOXA9/Meis1 model of CN-AML.

Mulgrew NM, Kettyle LM, Ramsey JM, Cull S, Smyth LJ, Mervyn DM, Bijl JJ, Thompson A.

Dev Dyn. 2014 Jan;243(1):172-81. doi: 10.1002/dvdy.24070. Epub 2013 Dec 4.


DNA hypermethylation and DNA hypomethylation is present at different loci in chronic kidney disease.

Smyth LJ, McKay GJ, Maxwell AP, McKnight AJ.

Epigenetics. 2014 Mar;9(3):366-76. doi: 10.4161/epi.27161. Epub 2013 Nov 19.


T lymphocyte insensitivity to corticosteroids in chronic obstructive pulmonary disease.

Kaur M, Smyth LJ, Cadden P, Grundy S, Ray D, Plumb J, Singh D.

Respir Res. 2012 Mar 14;13:20. doi: 10.1186/1465-9921-13-20.


Identification of cells expressing IL-17A and IL-17F in the lungs of patients with COPD.

Eustace A, Smyth LJC, Mitchell L, Williamson K, Plumb J, Singh D.

Chest. 2011 May;139(5):1089-1100. doi: 10.1378/chest.10-0779. Epub 2010 Sep 23.


Increased airway T regulatory cells in asthmatic subjects.

Smyth LJ, Eustace A, Kolsum U, Blaikely J, Singh D.

Chest. 2010 Oct;138(4):905-12. doi: 10.1378/chest.09-3079. Epub 2010 May 7.


Increased T-regulatory cells within lymphocyte follicles in moderate COPD.

Plumb J, Smyth LJ, Adams HR, Vestbo J, Bentley A, Singh SD.

Eur Respir J. 2009 Jul;34(1):89-94. doi: 10.1183/09031936.00100708. Epub 2009 Feb 5.


CD8 chemokine receptors in chronic obstructive pulmonary disease.

Smyth LJ, Starkey C, Gordon FS, Vestbo J, Singh D.

Clin Exp Immunol. 2008 Oct;154(1):56-63. doi: 10.1111/j.1365-2249.2008.03729.x. Epub 2008 Aug 22.


CD4-regulatory cells in COPD patients.

Smyth LJ, Starkey C, Vestbo J, Singh D.

Chest. 2007 Jul;132(1):156-63. Epub 2007 May 15.


Role of the mucosal integrin alpha(E)(CD103)beta(7) in tissue-restricted cytotoxicity.

Smyth LJ, Kirby JA, Cunningham AC.

Clin Exp Immunol. 2007 Jul;149(1):162-70. Epub 2007 Apr 2.


CD8 T-cell recognition of human 5T4 oncofetal antigen.

Smyth LJ, Elkord E, Taher TE, Jiang HR, Burt DJ, Clayton A, van Veelen PA, de Ru A, Ossendorp F, Melief CJ, Drijfhout JW, Dermime S, Hawkins RE, Stern PL.

Int J Cancer. 2006 Oct 1;119(7):1638-47.


Effect of TA-CIN (HPV 16 L2E6E7) booster immunisation in vulval intraepithelial neoplasia patients previously vaccinated with TA-HPV (vaccinia virus encoding HPV 16/18 E6E7).

Davidson EJ, Faulkner RL, Sehr P, Pawlita M, Smyth LJ, Burt DJ, Tomlinson AE, Hickling J, Kitchener HC, Stern PL.

Vaccine. 2004 Jul 29;22(21-22):2722-9.


Immunological responses in women with human papillomavirus type 16 (HPV-16)-associated anogenital intraepithelial neoplasia induced by heterologous prime-boost HPV-16 oncogene vaccination.

Smyth LJ, Van Poelgeest MI, Davidson EJ, Kwappenberg KM, Burt D, Sehr P, Pawlita M, Man S, Hickling JK, Fiander AN, Tristram A, Kitchener HC, Offringa R, Stern PL, Van Der Burg SH.

Clin Cancer Res. 2004 May 1;10(9):2954-61.


Protein and cell engineering of components of the human immunoglobulin E receptor/effector system: applications for therapy and diagnosis.

Helm BA, Sayers I, Swan J, Smyth LJ, Cain SA, Suter M, Machado DC, Spivey AC, Padlan EA.

Technol Health Care. 1998 Sep;6(2-3):195-207.


Fc gamma RIIa polymorphism in systemic lupus erythematosus.

Smyth LJ, Snowden N, Carthy D, Papasteriades C, Hajeer A, Ollier WE.

Ann Rheum Dis. 1997 Dec;56(12):744-6.

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