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Clinical significance of Pseudomonas aeruginosa 2-alkyl-4-quinolone quorum-sensing signal molecules for long-term outcomes in adults with cystic fibrosis.

Webb K, Fogarty A, Barrett DA, Nash EF, Whitehouse JL, Smyth AR, Stewart I, Knox A, Williams P, Halliday N, Cámara M, Barr HL.

J Med Microbiol. 2019 Oct 31. doi: 10.1099/jmm.0.001099. [Epub ahead of print]


Pro Con Debate - Infection prevention and control in cystic fibrosis: One size fits all The argument against.

Smyth AR, Smith SJ, Rowbotham NJ.

Paediatr Respir Rev. 2019 Aug 21. pii: S1526-0542(19)30066-1. doi: 10.1016/j.prrv.2019.08.001. [Epub ahead of print] Review.


Rojiroti microfinance and child nutrition: a cluster randomised trial.

Ojha S, Szatkowski L, Sinha R, Yaron G, Fogarty A, Allen SJ, Choudhary S, Smyth AR.

Arch Dis Child. 2019 Oct 10. pii: archdischild-2018-316471. doi: 10.1136/archdischild-2018-316471. [Epub ahead of print]


Using digital technology for home monitoring, adherence and self-management in cystic fibrosis: a state-of-the-art review.

Calthorpe RJ, Smith S, Gathercole K, Smyth AR.

Thorax. 2019 Oct 8. pii: thoraxjnl-2019-213233. doi: 10.1136/thoraxjnl-2019-213233. [Epub ahead of print]


Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis.

Bhatt J, Jahnke N, Smyth AR.

Cochrane Database Syst Rev. 2019 Sep 4;9:CD002009. doi: 10.1002/14651858.CD002009.pub7.


Adapting the James Lind Alliance priority setting process to better support patient participation: an example from cystic fibrosis.

Rowbotham NJ, Smith SJ, Elliott ZC, Leighton PA, Rayner OC, Morley R, Smyth AR.

Res Involv Engagem. 2019 Aug 20;5:24. doi: 10.1186/s40900-019-0159-x. eCollection 2019.


The effects of sprint training and the Nordic hamstring exercise on eccentric hamstring strength and sprint performance in adolescent athletes.

Freeman BW, Young WB, Talpey SW, Smyth AM, Pane CL, Carlon TA.

J Sports Med Phys Fitness. 2019 Jul;59(7):1119-1125. doi: 10.23736/S0022-4707.18.08703-0.


Advance care plan barriers in older patients with end-stage renal disease: a qualitative nephrologist interview study.

O'Riordan J, Noble H, Kane PM, Smyth A.

BMJ Support Palliat Care. 2019 Jun 25. pii: bmjspcare-2018-001759. doi: 10.1136/bmjspcare-2018-001759. [Epub ahead of print]


Do current clinical trials in cystic fibrosis match the priorities of patients and clinicans? A systematic review.

Kalaitzis IS, Rowbotham NJ, Smith SJ, Smyth AR.

J Cyst Fibros. 2019 Jun 21. pii: S1569-1993(19)30806-9. doi: 10.1016/j.jcf.2019.06.005. [Epub ahead of print]



Smyth AI, Osmanska J, Lip S, Chong PS, Dalzell JR.

Ulster Med J. 2019 Jan;88(1):56. Epub 2019 Jan 22. No abstract available.


Subcellular Localization of NR4A2 Orphan Nuclear Receptor Expression in Human and Mouse Synovial Joint Tissue.

Smyth A, Gogarty M, Crean D, Murphy EP.

Methods Mol Biol. 2019;1966:17-26. doi: 10.1007/978-1-4939-9195-2_3.


Socioeconomic status and risk of cardiovascular disease in 20 low-income, middle-income, and high-income countries: the Prospective Urban Rural Epidemiologic (PURE) study.

Rosengren A, Smyth A, Rangarajan S, Ramasundarahettige C, Bangdiwala SI, AlHabib KF, Avezum A, Bengtsson Boström K, Chifamba J, Gulec S, Gupta R, Igumbor EU, Iqbal R, Ismail N, Joseph P, Kaur M, Khatib R, Kruger IM, Lamelas P, Lanas F, Lear SA, Li W, Wang C, Quiang D, Wang Y, Lopez-Jaramillo P, Mohammadifard N, Mohan V, Mony PK, Poirier P, Srilatha S, Szuba A, Teo K, Wielgosz A, Yeates KE, Yusoff K, Yusuf R, Yusufali AH, Attaei MW, McKee M, Yusuf S.

Lancet Glob Health. 2019 Jun;7(6):e748-e760. doi: 10.1016/S2214-109X(19)30045-2. Epub 2019 Apr 23.


Climate change and lung health: presidential failure, professional responsibility.

Hopkinson NS, Hart N, Jenkins G, Rosenfeld M, Smyth AR, Wilkinson AJK, Kaminski N.

Thorax. 2019 Jul;74(7):627-628. doi: 10.1136/thoraxjnl-2019-213184. Epub 2019 Apr 21. No abstract available.


Patient engagement to prioritise CF research: Inclusive or selective?

Rowbotham NJ, Smyth AR.

J Cyst Fibros. 2019 May;18(3):307-308. doi: 10.1016/j.jcf.2019.04.006. Epub 2019 Apr 12. No abstract available.


Infection prevention and control in cystic fibrosis: a systematic review of interventions.

Rowbotham NJ, Palser SC, Smith SJ, Smyth AR.

Expert Rev Respir Med. 2019 May;13(5):425-434. doi: 10.1080/17476348.2019.1595594. Epub 2019 Mar 26.


Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study.

O'Donnell M, Mente A, Rangarajan S, McQueen MJ, O'Leary N, Yin L, Liu X, Swaminathan S, Khatib R, Rosengren A, Ferguson J, Smyth A, Lopez-Jaramillo P, Diaz R, Avezum A, Lanas F, Ismail N, Yusoff K, Dans A, Iqbal R, Szuba A, Mohammadifard N, Oguz A, Yusufali AH, Alhabib KF, Kruger IM, Yusuf R, Chifamba J, Yeates K, Dagenais G, Wielgosz A, Lear SA, Teo K, Yusuf S; PURE Investigators.

BMJ. 2019 Mar 13;364:l772. doi: 10.1136/bmj.l772.


Cleft Palate Outcomes and Prognostic Impact of Palatal Fistula on Subsequent Velopharyngeal Function-A Retrospective Cohort Study.

Smyth AG, Wu J.

Cleft Palate Craniofac J. 2019 Sep;56(8):1008-1012. doi: 10.1177/1055665619829388. Epub 2019 Feb 12.


Reply: More on Causal Inference Studies.

Lederer DJ, Bell SC, Smyth AR, Chalmers JD.

Ann Am Thorac Soc. 2019 May;16(5):646. doi: 10.1513/AnnalsATS.201901-070LE. No abstract available.


Reply to 'Consider species specialism when publishing datasets' and 'Decision trees for data publishing may exacerbate conservation conflict'.

Tulloch AIT, Auerbach N, Avery-Gomm S, Dickman CR, Fisher DO, Grantham H, Holden MH, Lavery TH, Leseberg NP, O'Connor J, Roberson L, Smyth AK, Stone Z, Tulloch V, Turak E, Watson JEM, Wardle GM.

Nat Ecol Evol. 2019 Mar;3(3):320-321. doi: 10.1038/s41559-019-0805-6. No abstract available.


COSUTI: a protocol for the development of a core outcome set (COS) for interventions for the treatment of uncomplicated urinary tract infection (UTI) in adults.

Duane S, Vellinga A, Murphy AW, Cormican M, Smyth A, Healy P, Moore M, Little P, Devane D.

Trials. 2019 Feb 7;20(1):106. doi: 10.1186/s13063-019-3194-x.


An Irish National Diabetes in Pregnancy Audit: aiming for best outcomes for women with diabetes.

Egan AM, Brassill MJ, Brosnan E, Carmody L, Clarke H, Coogan Kelly C, Culliney L, Durkan M, Fenlon M, Ferry P, Hanlon G, Higgins T, Hoashi S, Khamis A, Kinsley B, Kinsley T, Kirwan B, Liew A, McGurk C, McHugh C, Murphy MS, Murphy P, O'Halloran D, O'Mahony L, O'Sullivan E, Nolan M, Peter M, Roberts G, Smyth A, Todd M, Tuthill A, Wan Mahmood WA, Yousif O, P Dunne F; National Diabetes in Pregnancy Audit working group.

Diabet Med. 2019 Feb 2. doi: 10.1111/dme.13923. [Epub ahead of print]


Is microfinance associated with changes in women's well-being and children's nutrition? A systematic review and meta-analysis.

Gichuru W, Ojha S, Smith S, Smyth AR, Szatkowski L.

BMJ Open. 2019 Jan 28;9(1):e023658. doi: 10.1136/bmjopen-2018-023658.


Velopharyngeal insufficiency after maxillary advancement in patients with cleft palate - a survey of risk assessment in the United Kingdom and Ireland.

Fitzgerald R, Smyth A.

Br J Oral Maxillofac Surg. 2019 Jan;57(1):58-61. doi: 10.1016/j.bjoms.2018.11.006. Epub 2018 Dec 8.


Global trait-environment relationships of plant communities.

Bruelheide H, Dengler J, Purschke O, Lenoir J, Jiménez-Alfaro B, Hennekens SM, Botta-Dukát Z, Chytrý M, Field R, Jansen F, Kattge J, Pillar VD, Schrodt F, Mahecha MD, Peet RK, Sandel B, van Bodegom P, Altman J, Alvarez-Dávila E, Arfin Khan MAS, Attorre F, Aubin I, Baraloto C, Barroso JG, Bauters M, Bergmeier E, Biurrun I, Bjorkman AD, Blonder B, Čarni A, Cayuela L, Černý T, Cornelissen JHC, Craven D, Dainese M, Derroire G, De Sanctis M, Díaz S, Doležal J, Farfan-Rios W, Feldpausch TR, Fenton NJ, Garnier E, Guerin GR, Gutiérrez AG, Haider S, Hattab T, Henry G, Hérault B, Higuchi P, Hölzel N, Homeier J, Jentsch A, Jürgens N, Kącki Z, Karger DN, Kessler M, Kleyer M, Knollová I, Korolyuk AY, Kühn I, Laughlin DC, Lens F, Loos J, Louault F, Lyubenova MI, Malhi Y, Marcenò C, Mencuccini M, Müller JV, Munzinger J, Myers-Smith IH, Neill DA, Niinemets Ü, Orwin KH, Ozinga WA, Penuelas J, Pérez-Haase A, Petřík P, Phillips OL, Pärtel M, Reich PB, Römermann C, Rodrigues AV, Sabatini FM, Sardans J, Schmidt M, Seidler G, Silva Espejo JE, Silveira M, Smyth A, Sporbert M, Svenning JC, Tang Z, Thomas R, Tsiripidis I, Vassilev K, Violle C, Virtanen R, Weiher E, Welk E, Wesche K, Winter M, Wirth C, Jandt U.

Nat Ecol Evol. 2018 Dec;2(12):1906-1917. doi: 10.1038/s41559-018-0699-8. Epub 2018 Nov 19.


The current landscape of European registries for rare endocrine conditions.

Ali SR, Bryce J, Cools M, Korbonits M, Beun JG, Taruscio D, Danne T, Dattani M, Dekkers OM, Linglart A, Netchine I, Nordenstrom A, Patocs A, Persani L, Reisch N, Smyth A, Sumnik Z, Visser WE, Hiort O, Pereira AM, Ahmed SF.

Eur J Endocrinol. 2019 Jan 1;180(1):89-98. doi: 10.1530/EJE-18-0861.


The prevalence, clinical status and genotype of cystic fibrosis patients living in Cuba using national registry data.

Rodríguez-Calá F, Suárez-Medina R, Venero-Fernández SJ, Smyth A, Carr SB, Fogarty AW.

J Cyst Fibros. 2019 Jul;18(4):522-524. doi: 10.1016/j.jcf.2018.10.007. Epub 2018 Oct 23.


In situ identification of Gram-negative bacteria in human lungs using a topical fluorescent peptide targeting lipid A.

Akram AR, Chankeshwara SV, Scholefield E, Aslam T, McDonald N, Megia-Fernandez A, Marshall A, Mills B, Avlonitis N, Craven TH, Smyth AM, Collie DS, Gray C, Hirani N, Hill AT, Govan JR, Walsh T, Haslett C, Bradley M, Dhaliwal K.

Sci Transl Med. 2018 Oct 24;10(464). pii: eaal0033. doi: 10.1126/scitranslmed.aal0033.


Diagnostic Utility of Computed Tomographic Angiography in Giant-Cell Arteritis.

Conway R, Smyth AE, Kavanagh RG, O'Donohoe RL, Purcell Y, Heffernan EJ, Molloy ES, McNeill G, Killeen RP.

Stroke. 2018 Sep;49(9):2233-2236. doi: 10.1161/STROKEAHA.118.021995.


Gaps in the evidence for treatment decisions in cystic fibrosis: a systematic review.

Rowbotham NJ, Smith S, Prayle AP, Robinson KA, Smyth AR.

Thorax. 2019 Mar;74(3):229-236. doi: 10.1136/thoraxjnl-2017-210858. Epub 2018 Oct 9.


Control of Confounding and Reporting of Results in Causal Inference Studies. Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals.

Lederer DJ, Bell SC, Branson RD, Chalmers JD, Marshall R, Maslove DM, Ost DE, Punjabi NM, Schatz M, Smyth AR, Stewart PW, Suissa S, Adjei AA, Akdis CA, Azoulay É, Bakker J, Ballas ZK, Bardin PG, Barreiro E, Bellomo R, Bernstein JA, Brusasco V, Buchman TG, Chokroverty S, Collop NA, Crapo JD, Fitzgerald DA, Hale L, Hart N, Herth FJ, Iwashyna TJ, Jenkins G, Kolb M, Marks GB, Mazzone P, Moorman JR, Murphy TM, Noah TL, Reynolds P, Riemann D, Russell RE, Sheikh A, Sotgiu G, Swenson ER, Szczesniak R, Szymusiak R, Teboul JL, Vincent JL.

Ann Am Thorac Soc. 2019 Jan;16(1):22-28. doi: 10.1513/AnnalsATS.201808-564PS. No abstract available. Erratum in: Ann Am Thorac Soc. 2019 Feb;16(2):283.


Bronchoscopy-guided antimicrobial therapy for cystic fibrosis.

Jain K, Wainwright C, Smyth AR.

Cochrane Database Syst Rev. 2018 Sep 17;9:CD009530. doi: 10.1002/14651858.CD009530.pub4. Review.


Staphylococcus aureus in cystic fibrosis: pivotal role or bit part actor?

Hurley MN, Smyth AR.

Curr Opin Pulm Med. 2018 Nov;24(6):586-591. doi: 10.1097/MCP.0000000000000518. Review.


A decision tree for assessing the risks and benefits of publishing biodiversity data.

Tulloch AIT, Auerbach N, Avery-Gomm S, Bayraktarov E, Butt N, Dickman CR, Ehmke G, Fisher DO, Grantham H, Holden MH, Lavery TH, Leseberg NP, Nicholls M, O'Connor J, Roberson L, Smyth AK, Stone Z, Tulloch V, Turak E, Wardle GM, Watson JEM.

Nat Ecol Evol. 2018 Aug;2(8):1209-1217. doi: 10.1038/s41559-018-0608-1. Epub 2018 Jul 23. Review.


Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis.

Lo DK, Muhlebach MS, Smyth AR.

Cochrane Database Syst Rev. 2018 Jul 21;7:CD009650. doi: 10.1002/14651858.CD009650.pub4. Review.


Out-of-hospital cardiac arrest termination of resuscitation with ongoing CPR: An observational study.

Yates EJ, Schmidbauer S, Smyth AM, Ward M, Dorrian S, Siriwardena AN, Friberg H, Perkins GD.

Resuscitation. 2018 Sep;130:21-27. doi: 10.1016/j.resuscitation.2018.06.021. Epub 2018 Jun 27.


Aortic Calcification in a Patient with a Gain-of-Function STAT1 Mutation.

Smyth AE, Kaleviste E, Snow A, Kisand K, McMahon CJ, Cant AJ, Leahy TR.

J Clin Immunol. 2018 May;38(4):468-470. doi: 10.1007/s10875-018-0513-z. Epub 2018 May 26. No abstract available.


Comparative 'omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli.

Malone KM, Rue-Albrecht K, Magee DA, Conlon K, Schubert OT, Nalpas NC, Browne JA, Smyth A, Gormley E, Aebersold R, MacHugh DE, Gordon SV.

Microb Genom. 2018 Mar;4(3). doi: 10.1099/mgen.0.000163. Epub 2018 Mar 20.


ECFS best practice guidelines: the 2018 revision.

Castellani C, Duff AJA, Bell SC, Heijerman HGM, Munck A, Ratjen F, Sermet-Gaudelus I, Southern KW, Barben J, Flume PA, Hodková P, Kashirskaya N, Kirszenbaum MN, Madge S, Oxley H, Plant B, Schwarzenberg SJ, Smyth AR, Taccetti G, Wagner TOF, Wolfe SP, Drevinek P.

J Cyst Fibros. 2018 Mar;17(2):153-178. doi: 10.1016/j.jcf.2018.02.006. Epub 2018 Mar 3. Review.


Variation in benthic metabolism and nitrogen cycling across clam aquaculture sites.

Murphy AE, Nizzoli D, Bartoli M, Smyth AR, Castaldelli G, Anderson IC.

Mar Pollut Bull. 2018 Feb;127:524-535. doi: 10.1016/j.marpolbul.2017.12.003. Epub 2017 Dec 21.


Experimental infection of cattle with Mycobacterium tuberculosis isolates shows the attenuation of the human tubercle bacillus for cattle.

Villarreal-Ramos B, Berg S, Whelan A, Holbert S, Carreras F, Salguero FJ, Khatri BL, Malone K, Rue-Albrecht K, Shaughnessy R, Smyth A, Ameni G, Aseffa A, Sarradin P, Winter N, Vordermeier M, Gordon SV.

Sci Rep. 2018 Jan 17;8(1):894. doi: 10.1038/s41598-017-18575-5.


Existing knowledge of linguistic structure mitigates associative memory deficits in older adults.

Smyth AC, Naveh-Benjamin M.

Exp Aging Res. 2018 Jan-Feb;44(1):35-47. doi: 10.1080/0361073X.2017.1398517. Epub 2018 Jan 5.


When Less Is More: Optimizing Care for Elderly Patients Failing to Thrive on Dialysis.

O'Riordan J, Kane PM, Noble H, Beatty S, Mannion E, Murtagh C, Harnett I, Smyth A.

J Pain Symptom Manage. 2018 Apr;55(4):1241-1245. doi: 10.1016/j.jpainsymman.2017.12.475. Epub 2017 Dec 14. No abstract available.


Vitamin D Deficiency and Insufficiency Prevalence in the West of Ireland - A Retrospective Study.

Delos Reyes J, Smyth A, Griffin D, O'Shea P, O'Keeffe S, Mulkerrin EC.

J Nutr Health Aging. 2017;21(10):1107-1110. doi: 10.1007/s12603-017-0889-0.


Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: A longitudinal study; response to comments.

Barr HL, Halliday N, Barrett DA, Williams P, Forrester DL, Peckham D, Williams K, Smyth AR, Honeybourne D, Whitehouse JL, Nash EF, Dewar J, Clayton A, Knox AJ, Cámara M, Fogarty AW.

J Cyst Fibros. 2017 Nov;16(6):e21. doi: 10.1016/j.jcf.2017.09.008. Epub 2017 Oct 25. No abstract available.


Early Respiratory Bacterial Detection and Antistaphylococcal Antibiotic Prophylaxis in Young Children with Cystic Fibrosis.

Hurley MN, Fogarty A, McKeever TM, Goss CH, Rosenfeld M, Smyth AR.

Ann Am Thorac Soc. 2018 Jan;15(1):42-48. doi: 10.1513/AnnalsATS.201705-376OC.


Weight gain during acute treatment of an initial pulmonary exacerbation is associated with a longer interval to the next exacerbation in adults with cystic fibrosis.

Barr HL, Cámara M, Barrett D, Williams P, Forrester D, Smyth A, Honeybourne D, Whitehouse J, Nash E, Dewar J, Knox A, Fogarty AW.

ERJ Open Res. 2017 Aug 25;3(3). pii: 00057-2017. doi: 10.1183/23120541.00057-2017. eCollection 2017 Jul.


The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and healthcare providers.

Rowbotham NJ, Smith S, Leighton PA, Rayner OC, Gathercole K, Elliott ZC, Nash EF, Daniels T, Duff AJA, Collins S, Chandran S, Peaple U, Hurley MN, Brownlee K, Smyth AR.

Thorax. 2018 Apr;73(4):388-390. doi: 10.1136/thoraxjnl-2017-210473. Epub 2017 Aug 4.


Publish openly but responsibly.

Lowe AJ, Smyth AK, Atkins K, Avery R, Belbin L, Brown N, Budden AE, Gioia P, Guru S, Hardie M, Hirsch T, Hobern D, La Salle J, Loarie SR, Miles M, Milne D, Nicholls M, Rossetto M, Smits J, Sparrow B, Terrill G, Turner D, Wardle GM.

Science. 2017 Jul 14;357(6347):141. doi: 10.1126/science.aao0054. No abstract available.


Investigating the variation in the incidence of new Pseudomonas aeruginosa infection between paediatric cystic fibrosis centres.

Gilchrist FJ, Jones AM, Smyth AR, Southern KW, Webb AK, Lenney W.

J Cyst Fibros. 2017 Sep;16(5):e14-e16. doi: 10.1016/j.jcf.2017.06.006. Epub 2017 Jul 6. No abstract available.


Nutrition in Renal Supportive Care: Patient-driven and flexible.

Stevenson J, Meade A, Randall AM, Manley K, Notaras S, Heaney S, Chan M, Smyth A, Josland E, Brennan FP, Brown MA.

Nephrology (Carlton). 2017 Oct;22(10):739-747. doi: 10.1111/nep.13090. Review.


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