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Items: 1 to 50 of 350

1.

Hepatocellular Carcinoma Detection by Plasma Methylated DNA: Discovery, Phase I Pilot, and Phase II Clinical Validation.

Kisiel JB, Dukek BA, Kanipakam RVSR, Ghoz HM, Yab TC, Berger CK, Taylor WR, Foote PH, Giama NH, Onyirioha K, Abdallah MA, Burger KN, Slettedahl SW, Mahoney DW, Smyrk TC, Lewis JT, Giakoumopoulos M, Allawi HT, Lidgard G, Roberts LR, Ahlquist DA.

Hepatology. 2018 Aug 31. doi: 10.1002/hep.30244. [Epub ahead of print]

PMID:
30168613
2.

Identification of prognostic phenotypes of esophageal adenocarcinoma in two independent cohorts.

Sawas T, Killcoyne S, Iyer PG, Wang KK, Smyrk TC, Kisiel JB, Qin Y, Ahlquist DA, Rustgi AK; OCCAMS Consortium, Costa RJ, Gerstung M, Fitzgerald RC, Katzka DA.

Gastroenterology. 2018 Aug 27. pii: S0016-5085(18)34923-0. doi: 10.1053/j.gastro.2018.08.036. [Epub ahead of print]

PMID:
30165050
3.

A Tale of Three Tails and a Cystic Lesion: A Rare Cause of Recurrent Acute Pancreatitis.

Nagpal SJS, Levy MJ, Takahashi N, Kendrick ML, Smyrk TC, Pearson RK, Majumder S.

Am J Gastroenterol. 2018 Jul 2. doi: 10.1038/s41395-018-0178-5. [Epub ahead of print] No abstract available.

PMID:
29961770
4.

Highly Discriminant Methylated DNA Markers for the Non-endoscopic Detection of Barrett's Esophagus.

Iyer PG, Taylor WR, Johnson ML, Lansing RL, Maixner KA, Yab TC, Simonson JA, Devens ME, Slettedahl SW, Mahoney DW, Berger CK, Foote PH, Smyrk TC, Wang KK, Wolfsen HC, Ahlquist DA.

Am J Gastroenterol. 2018 Aug;113(8):1156-1166. doi: 10.1038/s41395-018-0107-7. Epub 2018 Jun 12.

PMID:
29891853
5.

Detection of Gastric Cancer with Novel Methylated DNA Markers: Discovery, Tissue Validation, and Pilot Testing in Plasma.

Anderson BW, Suh YS, Choi B, Lee HJ, Yab TC, Taylor W, Dukek BA, Berger CK, Cao X, Foote PH, Devens ME, Boardman LA, Kisiel JB, Mahoney DW, Slettedahl SW, Allawi HT, Lidgard GP, Smyrk TC, Yang HK, Ahlquist DA.

Clin Cancer Res. 2018 May 29. pii: clincanres.3364.2017. doi: 10.1158/1078-0432.CCR-17-3364. [Epub ahead of print]

PMID:
29844130
6.

A Comprehensive Approach to Sequence-oriented IsomiR annotation (CASMIR): demonstration with IsomiR profiling in colorectal neoplasia.

Wu CW, Evans JM, Huang S, Mahoney DW, Dukek BA, Taylor WR, Yab TC, Smyrk TC, Jen J, Kisiel JB, Ahlquist DA.

BMC Genomics. 2018 May 25;19(1):401. doi: 10.1186/s12864-018-4794-7.

7.

Fasting Blood Glucose Levels Provide Estimate of Duration and Progression of Pancreatic Cancer Before Diagnosis.

Sharma A, Smyrk TC, Levy MJ, Topazian MA, Chari ST.

Gastroenterology. 2018 Aug;155(2):490-500.e2. doi: 10.1053/j.gastro.2018.04.025. Epub 2018 Apr 30.

PMID:
29723506
8.

Outcome of Mismatch Repair-Deficient Metastatic Colorectal Cancer: The Mayo Clinic Experience.

Jin Z, Sanhueza CT, Johnson B, Nagorney DM, Larson DW, Mara KC, Harmsen WC, Smyrk TC, Grothey A, Hubbard JM.

Oncologist. 2018 Sep;23(9):1083-1091. doi: 10.1634/theoncologist.2017-0289. Epub 2018 Apr 19.

PMID:
29674439
9.

Prognostic factors and benefits of adjuvant therapy after pancreatoduodenectomy for ampullary adenocarcinoma: Mayo Clinic experience.

Jin Z, Hartgers ML, Sanhueza CT, Shubert CR, Alberts SR, Truty MJ, Muppa P, Nagorney DM, Smyrk TC, Hassan M, Mahipal A.

Eur J Surg Oncol. 2018 May;44(5):677-683. doi: 10.1016/j.ejso.2018.02.008. Epub 2018 Feb 16.

PMID:
29506768
10.

Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer.

Mouchli MA, Ouk L, Scheitel MR, Chaudhry AP, Felmlee-Devine D, Grill DE, Rashtak S, Wang P, Wang J, Chaudhry R, Smyrk TC, Oberg AL, Druliner BR, Boardman LA.

World J Gastroenterol. 2018 Feb 28;24(8):905-916. doi: 10.3748/wjg.v24.i8.905.

11.

Histologic and immunohistochemical differences between hereditary and sporadic diffuse gastric carcinoma.

Lee HE, Smyrk TC, Zhang L.

Hum Pathol. 2018 Apr;74:64-72. doi: 10.1016/j.humpath.2017.12.023. Epub 2018 Jan 4.

PMID:
29307626
12.

Corrigendum: Accuracy and Safety of the Cytosponge for Assessing Histologic Activity in Eosinophilic Esophagitis: A Two-Center Study.

Katzka DA, Smyrk TC, Alexander JA, Geno DM, Beitia RA, Chang AO, Shaheen NJ, Fitzgerald RC, Dellon ES.

Am J Gastroenterol. 2018 Feb;113(2):310. doi: 10.1038/ajg.2017.474. Epub 2017 Dec 19.

PMID:
29257149
13.

Identification of a pyruvate-to-lactate signature in pancreatic intraductal papillary mucinous neoplasms.

Penheiter AR, Deelchand DK, Kittelson E, Damgard SE, Murphy SJ, O'Brien DR, Bamlet WR, Passow MR, Smyrk TC, Couch FJ, Vasmatzis G, Port JD, Marjańska M, Carlson SK.

Pancreatology. 2018 Jan;18(1):46-53. doi: 10.1016/j.pan.2017.11.006. Epub 2017 Nov 14.

14.

Is Standard Histology Sufficient to Detect Cytomegalovirus Reactivation in Inflammatory Bowel Disease?

Tandon P, McCurdy JD, Smyrk TC.

Am J Clin Pathol. 2017 Nov 2;148(5):459-460. doi: 10.1093/ajcp/aqx045. No abstract available.

PMID:
29106458
15.

Practical Approach to the Flattened Duodenal Biopsy.

Smyrk TC.

Surg Pathol Clin. 2017 Dec;10(4):823-839. doi: 10.1016/j.path.2017.07.004. Epub 2017 Sep 23. Review.

PMID:
29103535
16.

Undifferentiated Pancreatic Carcinomas Display Enrichment for Frequency and Extent of PD-L1 Expression by Tumor Cells.

Lehrke HD, Graham RP, McWilliams RR, Lam-Himlin DM, Smyrk TC, Jenkins S, Dong H, Zhang L.

Am J Clin Pathol. 2017 Nov 2;148(5):441-449. doi: 10.1093/ajcp/aqx092.

PMID:
29069274
17.

Isolated Acute Terminal Ileitis Without Preexisting Inflammatory Bowel Disease Rarely Progresses to Crohn's Disease.

Tse CS, Deepak P, Smyrk TC, Raffals LE.

Dig Dis Sci. 2017 Dec;62(12):3557-3562. doi: 10.1007/s10620-017-4803-8. Epub 2017 Oct 24.

PMID:
29064015
18.

Role of Deficient DNA Mismatch Repair Status in Patients With Stage III Colon Cancer Treated With FOLFOX Adjuvant Chemotherapy: A Pooled Analysis From 2 Randomized Clinical Trials.

Zaanan A, Shi Q, Taieb J, Alberts SR, Meyers JP, Smyrk TC, Julie C, Zawadi A, Tabernero J, Mini E, Goldberg RM, Folprecht G, Van Laethem JL, Le Malicot K, Sargent DJ, Laurent-Puig P, Sinicrope FA.

JAMA Oncol. 2018 Mar 1;4(3):379-383. doi: 10.1001/jamaoncol.2017.2899.

PMID:
28983557
19.

Accuracy and Safety of the Cytosponge for Assessing Histologic Activity in Eosinophilic Esophagitis: A Two-Center Study.

Katzka DA, Smyrk TC, Alexander JA, Geno DM, Beitia RA, Chang AO, Shaheen NJ, Fitzgerald RC, Dellon ES.

Am J Gastroenterol. 2017 Oct;112(10):1538-1544. doi: 10.1038/ajg.2017.244. Epub 2017 Aug 15. Erratum in: Am J Gastroenterol. 2017 Dec 19;:.

20.

Recurrent Jejunal Intussusception Caused by Heterotopic Pancreas Mass.

Peeraphatdit T, Smyrk TC, Alexander GL.

Clin Gastroenterol Hepatol. 2017 Dec;15(12):e175-e176. doi: 10.1016/j.cgh.2017.07.006. Epub 2017 Jul 13. No abstract available.

PMID:
28711692
21.

Occurrence of IgG4 in Esophageal Lichen Planus.

Podboy AJ, Alexander JA, Smyrk TC, Halland M, Ravi K, Geno DM, Murray JA, Katzka DA.

Clin Gastroenterol Hepatol. 2017 Dec;15(12):1975-1977. doi: 10.1016/j.cgh.2017.06.008. Epub 2017 Jun 10. No abstract available.

PMID:
28606847
22.

North Central Cancer Treatment Group N0543 (Alliance): A phase 2 trial of pharmacogenetic-based dosing of irinotecan, oxaliplatin, and capecitabine as first-line therapy for patients with advanced small bowel adenocarcinoma.

McWilliams RR, Foster NR, Mahoney MR, Smyrk TC, Murray JA, Ames MM, Horvath LE, Schneider DJ, Hobday TJ, Jatoi A, Meyers JP, Goetz MP.

Cancer. 2017 Sep 15;123(18):3494-3501. doi: 10.1002/cncr.30766. Epub 2017 May 10.

23.

Constipation-Predominant Irritable Bowel Syndrome Females Have Normal Colonic Barrier and Secretory Function.

Peters SA, Edogawa S, Sundt WJ, Dyer RB, Dalenberg DA, Mazzone A, Singh RJ, Moses N, Smyrk TC, Weber C, Linden DR, MacNaughton WK, Turner JR, Camilleri M, Katzka DA, Farrugia G, Grover M.

Am J Gastroenterol. 2017 Jun;112(6):913-923. doi: 10.1038/ajg.2017.48. Epub 2017 Mar 21.

24.

Long-standing Crohn's disease and its implication on anal squamous cell cancer management.

Lightner AL, Moncrief SB, Smyrk TC, Pemberton JH, Haddock MG, Larson DW, Dozois EJ, Mathis KL.

Int J Colorectal Dis. 2017 May;32(5):661-666. doi: 10.1007/s00384-017-2794-8. Epub 2017 Mar 14.

PMID:
28293746
25.

Family history of colorectal cancer and its impact on survival in patients with resected stage III colon cancer: results from NCCTG Trial N0147 (Alliance).

Jansson-Knodell CL, Foster NR, Sargent DJ, Limburg PJ, Thibodeau SN, Smyrk TC, Sinicrope FA, Jahagirdar B, Goldberg RM, Alberts SR.

J Gastrointest Oncol. 2017 Feb;8(1):1-11. doi: 10.21037/jgo.2016.12.13.

26.

A Malignant Mimic.

Shergill S, Smyrk TC, Sweetser S.

Gastroenterology. 2017 Apr;152(5):953-955. doi: 10.1053/j.gastro.2016.11.015. Epub 2017 Mar 1. No abstract available.

PMID:
28259718
27.

Magnetic resonance elastography is accurate in detecting advanced fibrosis in autoimmune hepatitis.

Wang J, Malik N, Yin M, Smyrk TC, Czaja AJ, Ehman RL, Venkatesh SK.

World J Gastroenterol. 2017 Feb 7;23(5):859-868. doi: 10.3748/wjg.v23.i5.859.

28.

Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis.

Maskey RS, Flatten KS, Sieben CJ, Peterson KL, Baker DJ, Nam HJ, Kim MS, Smyrk TC, Kojima Y, Machida Y, Santiago A, van Deursen JM, Kaufmann SH, Machida YJ.

Nucleic Acids Res. 2017 May 5;45(8):4564-4576. doi: 10.1093/nar/gkx107.

29.

Beyond moulage sign and TTG levels: the role of cross-sectional imaging in celiac sprue.

Sheedy SP, Barlow JM, Fletcher JG, Smyrk TC, Scholz FJ, Codipilly DC, Al Bawardy BF, Fidler JL.

Abdom Radiol (NY). 2017 Feb;42(2):361-388. doi: 10.1007/s00261-016-1006-2. Review.

PMID:
28154909
30.

Malignant transformation of biliary adenofibroma: a rare biliary cystic tumor.

Thompson SM, Zendejas-Mummert B, Hartgers ML, Venkatesh SK, Smyrk TC, Mahipal A, Smoot RL.

J Gastrointest Oncol. 2016 Dec;7(6):E107-E112. doi: 10.21037/jgo.2016.09.14.

31.

Association of DNA Mismatch Repair and Mutations in BRAF and KRAS With Survival After Recurrence in Stage III Colon Cancers : A Secondary Analysis of 2 Randomized Clinical Trials.

Sinicrope FA, Shi Q, Allegra CJ, Smyrk TC, Thibodeau SN, Goldberg RM, Meyers JP, Pogue-Geile KL, Yothers G, Sargent DJ, Alberts SR.

JAMA Oncol. 2017 Apr 1;3(4):472-480. doi: 10.1001/jamaoncol.2016.5469.

32.

Emerging secondary syphilis presenting as syphilitic hepatitis.

Rubio-Tapia A, Hujoel IA, Smyrk TC, Poterucha JJ.

Hepatology. 2017 Jun;65(6):2113-2115. doi: 10.1002/hep.28974. Epub 2017 Apr 24. No abstract available.

PMID:
27981616
33.

Cytotoxic T Cells and Granzyme B Associated with Improved Colorectal Cancer Survival in a Prospective Cohort of Older Women.

Prizment AE, Vierkant RA, Smyrk TC, Tillmans LS, Nelson HH, Lynch CF, Pengo T, Thibodeau SN, Church TR, Cerhan JR, Anderson KE, Limburg PJ.

Cancer Epidemiol Biomarkers Prev. 2017 Apr;26(4):622-631. doi: 10.1158/1055-9965.EPI-16-0641. Epub 2016 Dec 15.

34.

Development of a Microscopic Colitis Disease Activity Index: a prospective cohort study.

Cotter TG, Binder M, Loftus EV Jr, Abboud R, McNally MA, Smyrk TC, Tremaine WJ, Sandborn WJ, Pardi DS.

Gut. 2018 Mar;67(3):441-446. doi: 10.1136/gutjnl-2016-313051. Epub 2016 Dec 13.

PMID:
27965284
35.

Phase I/II Randomized Trial of Sorafenib and Bevacizumab as First-Line Therapy in Patients with Locally Advanced or Metastatic Hepatocellular Carcinoma: North Central Cancer Treatment Group Trial N0745 (Alliance).

Hubbard JM, Mahoney MR, Loui WS, Roberts LR, Smyrk TC, Gatalica Z, Borad M, Kumar S, Alberts SR.

Target Oncol. 2017 Apr;12(2):201-209. doi: 10.1007/s11523-016-0467-0.

36.

The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD).

Sarmento OF, Svingen PA, Xiong Y, Sun Z, Bamidele AO, Mathison AJ, Smyrk TC, Nair AA, Gonzalez MM, Sagstetter MR, Baheti S, McGovern DP, Friton JJ, Papadakis KA, Gautam G, Xavier RJ, Urrutia RA, Faubion WA.

J Biol Chem. 2017 Jan 13;292(2):706-722. doi: 10.1074/jbc.M116.749663. Epub 2016 Dec 1.

37.

Presence of intraepithelial food antigen in patients with active eosinophilic oesophagitis.

Marietta EV, Geno DM, Smyrk TC, Becker A, Alexander JA, Camilleri M, Murray JA, Katzka DA.

Aliment Pharmacol Ther. 2017 Feb;45(3):427-433. doi: 10.1111/apt.13877. Epub 2016 Nov 22.

38.

Diagnostic Performance of MR Elastography and Vibration-controlled Transient Elastography in the Detection of Hepatic Fibrosis in Patients with Severe to Morbid Obesity.

Chen J, Yin M, Talwalkar JA, Oudry J, Glaser KJ, Smyrk TC, Miette V, Sandrin L, Ehman RL.

Radiology. 2017 May;283(2):418-428. doi: 10.1148/radiol.2016160685. Epub 2016 Nov 18.

39.

Oesophageal lichen planus: the efficacy of topical steroid-based therapies.

Podboy A, Sunjaya D, Smyrk TC, Murray JA, Binder M, Katzka DA, Alexander JA, Halland M.

Aliment Pharmacol Ther. 2017 Jan;45(2):310-318. doi: 10.1111/apt.13856. Epub 2016 Nov 17.

40.

Increased Rates of Clostridium difficile Infection and Poor Outcomes in Patients with IBD with Cytomegalovirus.

McCurdy JD, Enders FT, Khanna S, Bruining DH, Jones A, Killian JM, Tariq R, Smyrk TC, Loftus EV Jr.

Inflamm Bowel Dis. 2016 Nov;22(11):2688-2693.

PMID:
27755270
41.

Shifts in the Fecal Microbiota Associated with Adenomatous Polyps.

Hale VL, Chen J, Johnson S, Harrington SC, Yab TC, Smyrk TC, Nelson H, Boardman LA, Druliner BR, Levin TR, Rex DK, Ahnen DJ, Lance P, Ahlquist DA, Chia N.

Cancer Epidemiol Biomarkers Prev. 2017 Jan;26(1):85-94. doi: 10.1158/1055-9965.EPI-16-0337. Epub 2016 Sep 26.

42.

Montelukast Does not Maintain Symptom Remission After Topical Steroid Therapy for Eosinophilic Esophagitis.

Alexander JA, Ravi K, Enders FT, Geno DM, Kryzer LA, Mara KC, Smyrk TC, Katzka DA.

Clin Gastroenterol Hepatol. 2017 Feb;15(2):214-221.e2. doi: 10.1016/j.cgh.2016.09.013. Epub 2016 Sep 17.

PMID:
27650328
43.

Optimization of a Scoring System to Predict Microscopic Colitis in a Cohort of Patients With Chronic Diarrhea.

Cotter TG, Binder M, Harper EP, Smyrk TC, Pardi DS.

J Clin Gastroenterol. 2017 Mar;51(3):228-234. doi: 10.1097/MCG.0000000000000565.

PMID:
27404403
44.

A Biomarker Panel to Detect Synchronous Neoplasm in Non-neoplastic Surveillance Biopsies from Patients with Ulcerative Colitis.

Garrity-Park MM, Loftus EV Jr, Bryant SC, Smyrk TC.

Inflamm Bowel Dis. 2016 Jul;22(7):1568-74. doi: 10.1097/MIB.0000000000000789.

PMID:
27135485
45.

Innovative gastric endoscopic muscle biopsy to identify all cell types, including myenteric neurons and interstitial cells of Cajal in patients with idiopathic gastroparesis: a feasibility study (with video).

Rajan E, Gostout CJ, Wong Kee Song LM, Szarka LA, Kashyap PC, Smyrk TC, Bingener J, Deters JL, Knipschield MA, Bernard CE, Farrugia G.

Gastrointest Endosc. 2016 Sep;84(3):512-7. doi: 10.1016/j.gie.2016.04.029. Epub 2016 Apr 27.

46.

Obstructive jaundice in autoimmune pancreatitis can be safely treated with corticosteroids alone without biliary stenting.

Bi Y, Hart PA, Law R, Clain JE, Farnell MB, Gleeson FC, Kendrick ML, Levy MJ, Pearson RK, Petersen BT, Pisney LD, Smyrk TC, Takahashi N, Topazian MD, Vege SS, Chari ST.

Pancreatology. 2016 May-Jun;16(3):391-6. doi: 10.1016/j.pan.2016.03.017. Epub 2016 Apr 6.

PMID:
27107633
47.

DNA Methylation and Mutation of Small Colonic Neoplasms in Ulcerative Colitis and Crohn's Colitis: Implications for Surveillance.

Johnson DH, Taylor WR, Aboelsoud MM, Foote PH, Yab TC, Cao X, Smyrk TC, Loftus EV Jr, Mahoney DW, Ahlquist DA, Kisiel JB.

Inflamm Bowel Dis. 2016 Jul;22(7):1559-67. doi: 10.1097/MIB.0000000000000795.

48.

Pancreatic cyst epithelial denudation: a natural phenomenon in the absence of treatment.

Gómez V, Majumder S, Smyrk TC, Topazian MD, Chari ST, Gleeson FC, Harmsen WS, Enders FT, Abu Dayyeh BK, Iyer PG, Pearson RK, Petersen BT, Rajan E, Takahashi N, Vege SS, Wang KK, Levy MJ.

Gastrointest Endosc. 2016 Nov;84(5):788-793. doi: 10.1016/j.gie.2016.03.1502. Epub 2016 Apr 6.

PMID:
27060714
49.

Diabetes Mellitus Is Associated With an Exocrine Pancreatopathy: Conclusions From a Review of Literature.

Mohapatra S, Majumder S, Smyrk TC, Zhang L, Matveyenko A, Kudva YC, Chari ST.

Pancreas. 2016 Sep;45(8):1104-10. doi: 10.1097/MPA.0000000000000609. Review.

50.

Tumor eosinophil infiltration and improved survival of colorectal cancer patients: Iowa Women's Health Study.

Prizment AE, Vierkant RA, Smyrk TC, Tillmans LS, Lee JJ, Sriramarao P, Nelson HH, Lynch CF, Thibodeau SN, Church TR, Cerhan JR, Anderson KE, Limburg PJ.

Mod Pathol. 2016 May;29(5):516-27. doi: 10.1038/modpathol.2016.42. Epub 2016 Feb 26.

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