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Items: 1 to 50 of 364

1.

Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer.

McCleary-Wheeler AL, Carr RM, Palmer SR, Smyrk TC, Allred JB, Almada LL, Tolosa EJ, Lamberti MJ, Marks DL, Borad MJ, Molina JR, Qi Y, Lingle WL, Grothey A, Pitot HC, Jatoi A, Northfelt DW, Bryce AH, McWilliams RR, Okuno SH, Haluska P, Kim GP, Colon-Otero G, Lowe VJ, Callstrom MR, Ma WW, Bekaii-Saab T, Hung MC, Erlichman C, Fernandez-Zapico ME.

Pancreatology. 2020 Jan;20(1):101-109. doi: 10.1016/j.pan.2019.11.011. Epub 2019 Nov 21.

PMID:
31787526
2.

Mesenchymal Hamartoma in Children: A Diagnostic Challenge.

Khan MR, Binkovitz LA, Smyrk TC, Potter DD Jr, Furuya KN.

Case Rep Pediatr. 2019 Sep 16;2019:4132842. doi: 10.1155/2019/4132842. eCollection 2019.

3.

Biliary Amyloidoma as a Cause for Pancreatitis.

Qin Y, Smyrk TC, Topazian MD.

Clin Gastroenterol Hepatol. 2019 Oct;17(11):A25-A26. doi: 10.1016/j.cgh.2018.06.029. No abstract available.

PMID:
31543243
4.

Discovery, Validation, and Application of Novel Methylated DNA Markers for Detection of Esophageal Cancer in Plasma.

Qin Y, Wu CW, Taylor WR, Sawas T, Burger KN, Mahoney DW, Sun Z, Yab TC, Lidgard GP, Allawi HT, Buttar NS, Smyrk TC, Iyer PG, Katzka DA, Ahlquist DA, Kisiel JB.

Clin Cancer Res. 2019 Dec 15;25(24):7396-7404. doi: 10.1158/1078-0432.CCR-19-0740. Epub 2019 Sep 16.

PMID:
31527170
5.

Survival benefit of neoadjuvant therapy in patients with non-metastatic pancreatic ductal adenocarcinoma: A propensity matching and intention-to-treat analysis.

Sugimoto M, Takahashi N, Farnell MB, Smyrk TC, Truty MJ, Nagorney DM, Smoot RL, Chari ST, Carter RE, Kendrick ML.

J Surg Oncol. 2019 Nov;120(6):976-984. doi: 10.1002/jso.25681. Epub 2019 Aug 26.

PMID:
31452208
6.

Methylated DNA in Pancreatic Juice Distinguishes Patients With Pancreatic Cancer From Controls.

Majumder S, Raimondo M, Taylor WR, Yab TC, Berger CK, Dukek BA, Cao X, Foote PH, Wu CW, Devens ME, Mahoney DW, Smyrk TC, Pannala R, Chari ST, Vege SS, Topazian MD, Petersen BT, Levy MJ, Rajan E, Gleeson FC, Abu Dayyeh B, Nguyen CC, Faigel DO, Woodward TA, Wallace MB, Petersen G, Allawi HT, Lidgard GP, Kisiel JB, Ahlquist DA.

Clin Gastroenterol Hepatol. 2020 Mar;18(3):676-683.e3. doi: 10.1016/j.cgh.2019.07.017. Epub 2019 Jul 16.

PMID:
31323382
7.

Novel Methylated DNA Markers Discriminate Advanced Neoplasia in Pancreatic Cysts: Marker Discovery, Tissue Validation, and Cyst Fluid Testing.

Majumder S, Taylor WR, Yab TC, Berger CK, Dukek BA, Cao X, Foote PH, Wu CW, Mahoney DW, Aslanian HR, Fernández-Del Castillo C, Doyle LA, Farrell JJ, Fisher WE, Lee LS, Lee YN, Park W, Rodrigues C, Gould Rothberg BE, Salem RR, Simeone DM, Urs S, Van Buren G, Smyrk TC, Allawi HT, Lidgard GP, Raimondo M, Chari ST, Kendrick ML, Kisiel JB, Topazian MD, Ahlquist DA.

Am J Gastroenterol. 2019 Sep;114(9):1539-1549. doi: 10.14309/ajg.0000000000000284.

PMID:
31306149
8.

Albumin In Situ Hybridization Can Be Positive in Adenocarcinomas and Other Tumors From Diverse Sites.

Nasir A, Lehrke HD, Mounajjed T, Said S, Zhang L, Yasir S, Shah SS, Chandan VS, Smyrk TC, Moreira RK, Boland Froemming JM, Herrera Hernandez LP, Wu TT, Graham RP.

Am J Clin Pathol. 2019 Jul 5;152(2):190-199. doi: 10.1093/ajcp/aqz032.

PMID:
31107526
9.

Idiopathic myointimal hyperplasia is a distinct cause of chronic colon ischaemia.

Anderson B, Smyrk TC, Graham RP, Lightner A, Sweetser S.

Colorectal Dis. 2019 Sep;21(9):1073-1078. doi: 10.1111/codi.14685. Epub 2019 May 29.

PMID:
31074117
10.

Solid Pseudopapillary Neoplasms of the Pancreas: A Large American Cohort.

Sanhueza CT, Huffman BM, Jin Z, Hartgers ML, Smyrk TC, Westin G, McWilliams RR, Ma WW, Alberts SR, Mahipal A.

Pancreas. 2019 Apr;48(4):e21-e22. doi: 10.1097/MPA.0000000000001288. No abstract available.

PMID:
30973464
11.

Staging of T1 esophageal adenocarcinoma with volumetric laser endomicroscopy: a feasibility study.

Kahn A, Kamboj AK, Muppa P, Sawas T, Lutzke LS, Buras MR, Golafshar MA, Katzka DA, Iyer PG, Smyrk TC, Wang KK, Leggett CL.

Endosc Int Open. 2019 Apr;7(4):E462-E470. doi: 10.1055/a-0838-5326. Epub 2019 Mar 21.

12.

A Phase II Randomized Trial of Panitumumab, Erlotinib, and Gemcitabine Versus Erlotinib and Gemcitabine in Patients with Untreated, Metastatic Pancreatic Adenocarcinoma: North Central Cancer Treatment Group Trial N064B (Alliance).

Halfdanarson TR, Foster NR, Kim GP, Meyers JP, Smyrk TC, McCullough AE, Ames MM, Jaffe JP, Alberts SR.

Oncologist. 2019 May;24(5):589-e160. doi: 10.1634/theoncologist.2018-0878. Epub 2019 Jan 24.

13.

Variation in Endoscopic Activity Assessment and Endoscopy Score Validation in Adults With Eosinophilic Esophagitis.

Schoepfer AM, Hirano I, Coslovsky M, Roumet MC, Zwahlen M, Kuehni CE, Hafner D, Alexander JA, Dellon ES, Gonsalves N, Leung J, Bussmann C, Collins MH, Newbury RO, Smyrk TC, Woosley JT, Yang GY, Romero Y, Katzka DA, Furuta GT, Gupta SK, Aceves SS, Chehade M, Spergel JM, Falk GW, Meltzer BA, Comer GM, Straumann A, Safroneeva E; International EEsAI Study Group.

Clin Gastroenterol Hepatol. 2019 Jul;17(8):1477-1488.e10. doi: 10.1016/j.cgh.2018.11.032. Epub 2018 Nov 23.

PMID:
30476587
14.

High-Grade Dysplasia in Resected Main-Duct Intraductal Papillary Mucinous Neoplasm (MD-IPMN) is Associated with an Increased Risk of Subsequent Pancreatic Cancer.

Majumder S, Philip NA, Singh Nagpal SJ, Takahashi N, Mara KC, Kendrick ML, Smyrk TC, Zhang L, Levy MJ, Gleeson FC, Petersen BT, Pearson RK, Topazian MD, Vege SS, Chari ST.

Am J Gastroenterol. 2019 Mar;114(3):524-529. doi: 10.1038/s41395-018-0403-2.

PMID:
30413822
15.

Hepatocellular Carcinoma Detection by Plasma Methylated DNA: Discovery, Phase I Pilot, and Phase II Clinical Validation.

Kisiel JB, Dukek BA, V S R Kanipakam R, Ghoz HM, Yab TC, Berger CK, Taylor WR, Foote PH, Giama NH, Onyirioha K, Abdallah MA, Burger KN, Slettedahl SW, Mahoney DW, Smyrk TC, Lewis JT, Giakoumopoulos M, Allawi HT, Lidgard GP, Roberts LR, Ahlquist DA.

Hepatology. 2019 Mar;69(3):1180-1192. doi: 10.1002/hep.30244. Epub 2019 Feb 5.

PMID:
30168613
16.

Identification of Prognostic Phenotypes of Esophageal Adenocarcinoma in 2 Independent Cohorts.

Sawas T, Killcoyne S, Iyer PG, Wang KK, Smyrk TC, Kisiel JB, Qin Y, Ahlquist DA, Rustgi AK, Costa RJ, Gerstung M, Fitzgerald RC, Katzka DA; OCCAMS Consortium.

Gastroenterology. 2018 Dec;155(6):1720-1728.e4. doi: 10.1053/j.gastro.2018.08.036. Epub 2018 Aug 27.

17.

A Tale of Three Tails and a Cystic Lesion: A Rare Cause of Recurrent Acute Pancreatitis.

Nagpal SJS, Levy MJ, Takahashi N, Kendrick ML, Smyrk TC, Pearson RK, Majumder S.

Am J Gastroenterol. 2018 Sep;113(9):1398-1399. doi: 10.1038/s41395-018-0178-5. Epub 2018 Jul 2. No abstract available.

PMID:
29961770
18.

Highly Discriminant Methylated DNA Markers for the Non-endoscopic Detection of Barrett's Esophagus.

Iyer PG, Taylor WR, Johnson ML, Lansing RL, Maixner KA, Yab TC, Simonson JA, Devens ME, Slettedahl SW, Mahoney DW, Berger CK, Foote PH, Smyrk TC, Wang KK, Wolfsen HC, Ahlquist DA.

Am J Gastroenterol. 2018 Aug;113(8):1156-1166. doi: 10.1038/s41395-018-0107-7. Epub 2018 Jun 12.

PMID:
29891853
19.

Detection of Gastric Cancer with Novel Methylated DNA Markers: Discovery, Tissue Validation, and Pilot Testing in Plasma.

Anderson BW, Suh YS, Choi B, Lee HJ, Yab TC, Taylor WR, Dukek BA, Berger CK, Cao X, Foote PH, Devens ME, Boardman LA, Kisiel JB, Mahoney DW, Slettedahl SW, Allawi HT, Lidgard GP, Smyrk TC, Yang HK, Ahlquist DA.

Clin Cancer Res. 2018 Nov 15;24(22):5724-5734. doi: 10.1158/1078-0432.CCR-17-3364. Epub 2018 May 29.

20.

A Comprehensive Approach to Sequence-oriented IsomiR annotation (CASMIR): demonstration with IsomiR profiling in colorectal neoplasia.

Wu CW, Evans JM, Huang S, Mahoney DW, Dukek BA, Taylor WR, Yab TC, Smyrk TC, Jen J, Kisiel JB, Ahlquist DA.

BMC Genomics. 2018 May 25;19(1):401. doi: 10.1186/s12864-018-4794-7.

21.

Fasting Blood Glucose Levels Provide Estimate of Duration and Progression of Pancreatic Cancer Before Diagnosis.

Sharma A, Smyrk TC, Levy MJ, Topazian MA, Chari ST.

Gastroenterology. 2018 Aug;155(2):490-500.e2. doi: 10.1053/j.gastro.2018.04.025. Epub 2018 Apr 30.

22.

Outcome of Mismatch Repair-Deficient Metastatic Colorectal Cancer: The Mayo Clinic Experience.

Jin Z, Sanhueza CT, Johnson B, Nagorney DM, Larson DW, Mara KC, Harmsen WC, Smyrk TC, Grothey A, Hubbard JM.

Oncologist. 2018 Sep;23(9):1083-1091. doi: 10.1634/theoncologist.2017-0289. Epub 2018 Apr 19.

23.

Prognostic factors and benefits of adjuvant therapy after pancreatoduodenectomy for ampullary adenocarcinoma: Mayo Clinic experience.

Jin Z, Hartgers ML, Sanhueza CT, Shubert CR, Alberts SR, Truty MJ, Muppa P, Nagorney DM, Smyrk TC, Hassan M, Mahipal A.

Eur J Surg Oncol. 2018 May;44(5):677-683. doi: 10.1016/j.ejso.2018.02.008. Epub 2018 Feb 16.

PMID:
29506768
24.

Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer.

Mouchli MA, Ouk L, Scheitel MR, Chaudhry AP, Felmlee-Devine D, Grill DE, Rashtak S, Wang P, Wang J, Chaudhry R, Smyrk TC, Oberg AL, Druliner BR, Boardman LA.

World J Gastroenterol. 2018 Feb 28;24(8):905-916. doi: 10.3748/wjg.v24.i8.905.

25.

Histologic and immunohistochemical differences between hereditary and sporadic diffuse gastric carcinoma.

Lee HE, Smyrk TC, Zhang L.

Hum Pathol. 2018 Apr;74:64-72. doi: 10.1016/j.humpath.2017.12.023. Epub 2018 Jan 4.

PMID:
29307626
26.

Corrigendum: Accuracy and Safety of the Cytosponge for Assessing Histologic Activity in Eosinophilic Esophagitis: A Two-Center Study.

Katzka DA, Smyrk TC, Alexander JA, Geno DM, Beitia RA, Chang AO, Shaheen NJ, Fitzgerald RC, Dellon ES.

Am J Gastroenterol. 2018 Feb;113(2):310. doi: 10.1038/ajg.2017.474. Epub 2017 Dec 19.

PMID:
29257149
27.

Identification of a pyruvate-to-lactate signature in pancreatic intraductal papillary mucinous neoplasms.

Penheiter AR, Deelchand DK, Kittelson E, Damgard SE, Murphy SJ, O'Brien DR, Bamlet WR, Passow MR, Smyrk TC, Couch FJ, Vasmatzis G, Port JD, Marjańska M, Carlson SK.

Pancreatology. 2018 Jan;18(1):46-53. doi: 10.1016/j.pan.2017.11.006. Epub 2017 Nov 14.

28.

Is Standard Histology Sufficient to Detect Cytomegalovirus Reactivation in Inflammatory Bowel Disease?

Tandon P, McCurdy JD, Smyrk TC.

Am J Clin Pathol. 2017 Nov 2;148(5):459-460. doi: 10.1093/ajcp/aqx045. No abstract available.

PMID:
29106458
29.

Practical Approach to the Flattened Duodenal Biopsy.

Smyrk TC.

Surg Pathol Clin. 2017 Dec;10(4):823-839. doi: 10.1016/j.path.2017.07.004. Epub 2017 Sep 23. Review.

PMID:
29103535
30.

Undifferentiated Pancreatic Carcinomas Display Enrichment for Frequency and Extent of PD-L1 Expression by Tumor Cells.

Lehrke HD, Graham RP, McWilliams RR, Lam-Himlin DM, Smyrk TC, Jenkins S, Dong H, Zhang L.

Am J Clin Pathol. 2017 Nov 2;148(5):441-449. doi: 10.1093/ajcp/aqx092.

PMID:
29069274
31.

Isolated Acute Terminal Ileitis Without Preexisting Inflammatory Bowel Disease Rarely Progresses to Crohn's Disease.

Tse CS, Deepak P, Smyrk TC, Raffals LE.

Dig Dis Sci. 2017 Dec;62(12):3557-3562. doi: 10.1007/s10620-017-4803-8. Epub 2017 Oct 24.

PMID:
29064015
32.

Role of Deficient DNA Mismatch Repair Status in Patients With Stage III Colon Cancer Treated With FOLFOX Adjuvant Chemotherapy: A Pooled Analysis From 2 Randomized Clinical Trials.

Zaanan A, Shi Q, Taieb J, Alberts SR, Meyers JP, Smyrk TC, Julie C, Zawadi A, Tabernero J, Mini E, Goldberg RM, Folprecht G, Van Laethem JL, Le Malicot K, Sargent DJ, Laurent-Puig P, Sinicrope FA.

JAMA Oncol. 2018 Mar 1;4(3):379-383. doi: 10.1001/jamaoncol.2017.2899.

33.

Accuracy and Safety of the Cytosponge for Assessing Histologic Activity in Eosinophilic Esophagitis: A Two-Center Study.

Katzka DA, Smyrk TC, Alexander JA, Geno DM, Beitia RA, Chang AO, Shaheen NJ, Fitzgerald RC, Dellon ES.

Am J Gastroenterol. 2017 Oct;112(10):1538-1544. doi: 10.1038/ajg.2017.244. Epub 2017 Aug 15. Erratum in: Am J Gastroenterol. 2017 Dec 19;:.

34.

Recurrent Jejunal Intussusception Caused by Heterotopic Pancreas Mass.

Peeraphatdit T, Smyrk TC, Alexander GL.

Clin Gastroenterol Hepatol. 2017 Dec;15(12):e175-e176. doi: 10.1016/j.cgh.2017.07.006. Epub 2017 Jul 13. No abstract available.

PMID:
28711692
35.

Occurrence of IgG4 in Esophageal Lichen Planus.

Podboy AJ, Alexander JA, Smyrk TC, Halland M, Ravi K, Geno DM, Murray JA, Katzka DA.

Clin Gastroenterol Hepatol. 2017 Dec;15(12):1975-1977. doi: 10.1016/j.cgh.2017.06.008. Epub 2017 Jun 10. No abstract available.

PMID:
28606847
36.

North Central Cancer Treatment Group N0543 (Alliance): A phase 2 trial of pharmacogenetic-based dosing of irinotecan, oxaliplatin, and capecitabine as first-line therapy for patients with advanced small bowel adenocarcinoma.

McWilliams RR, Foster NR, Mahoney MR, Smyrk TC, Murray JA, Ames MM, Horvath LE, Schneider DJ, Hobday TJ, Jatoi A, Meyers JP, Goetz MP.

Cancer. 2017 Sep 15;123(18):3494-3501. doi: 10.1002/cncr.30766. Epub 2017 May 10.

37.

Constipation-Predominant Irritable Bowel Syndrome Females Have Normal Colonic Barrier and Secretory Function.

Peters SA, Edogawa S, Sundt WJ, Dyer RB, Dalenberg DA, Mazzone A, Singh RJ, Moses N, Smyrk TC, Weber C, Linden DR, MacNaughton WK, Turner JR, Camilleri M, Katzka DA, Farrugia G, Grover M.

Am J Gastroenterol. 2017 Jun;112(6):913-923. doi: 10.1038/ajg.2017.48. Epub 2017 Mar 21.

38.

Long-standing Crohn's disease and its implication on anal squamous cell cancer management.

Lightner AL, Moncrief SB, Smyrk TC, Pemberton JH, Haddock MG, Larson DW, Dozois EJ, Mathis KL.

Int J Colorectal Dis. 2017 May;32(5):661-666. doi: 10.1007/s00384-017-2794-8. Epub 2017 Mar 14.

PMID:
28293746
39.

Family history of colorectal cancer and its impact on survival in patients with resected stage III colon cancer: results from NCCTG Trial N0147 (Alliance).

Jansson-Knodell CL, Foster NR, Sargent DJ, Limburg PJ, Thibodeau SN, Smyrk TC, Sinicrope FA, Jahagirdar B, Goldberg RM, Alberts SR.

J Gastrointest Oncol. 2017 Feb;8(1):1-11. doi: 10.21037/jgo.2016.12.13.

40.

A Malignant Mimic.

Shergill S, Smyrk TC, Sweetser S.

Gastroenterology. 2017 Apr;152(5):953-955. doi: 10.1053/j.gastro.2016.11.015. Epub 2017 Mar 1. No abstract available.

PMID:
28259718
41.

Magnetic resonance elastography is accurate in detecting advanced fibrosis in autoimmune hepatitis.

Wang J, Malik N, Yin M, Smyrk TC, Czaja AJ, Ehman RL, Venkatesh SK.

World J Gastroenterol. 2017 Feb 7;23(5):859-868. doi: 10.3748/wjg.v23.i5.859.

42.

Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis.

Maskey RS, Flatten KS, Sieben CJ, Peterson KL, Baker DJ, Nam HJ, Kim MS, Smyrk TC, Kojima Y, Machida Y, Santiago A, van Deursen JM, Kaufmann SH, Machida YJ.

Nucleic Acids Res. 2017 May 5;45(8):4564-4576. doi: 10.1093/nar/gkx107.

43.

Beyond moulage sign and TTG levels: the role of cross-sectional imaging in celiac sprue.

Sheedy SP, Barlow JM, Fletcher JG, Smyrk TC, Scholz FJ, Codipilly DC, Al Bawardy BF, Fidler JL.

Abdom Radiol (NY). 2017 Feb;42(2):361-388. doi: 10.1007/s00261-016-1006-2. Review.

PMID:
28154909
44.

Malignant transformation of biliary adenofibroma: a rare biliary cystic tumor.

Thompson SM, Zendejas-Mummert B, Hartgers ML, Venkatesh SK, Smyrk TC, Mahipal A, Smoot RL.

J Gastrointest Oncol. 2016 Dec;7(6):E107-E112. doi: 10.21037/jgo.2016.09.14.

45.

Association of DNA Mismatch Repair and Mutations in BRAF and KRAS With Survival After Recurrence in Stage III Colon Cancers : A Secondary Analysis of 2 Randomized Clinical Trials.

Sinicrope FA, Shi Q, Allegra CJ, Smyrk TC, Thibodeau SN, Goldberg RM, Meyers JP, Pogue-Geile KL, Yothers G, Sargent DJ, Alberts SR.

JAMA Oncol. 2017 Apr 1;3(4):472-480. doi: 10.1001/jamaoncol.2016.5469.

46.

Emerging secondary syphilis presenting as syphilitic hepatitis.

Rubio-Tapia A, Hujoel IA, Smyrk TC, Poterucha JJ.

Hepatology. 2017 Jun;65(6):2113-2115. doi: 10.1002/hep.28974. Epub 2017 Apr 24. No abstract available.

PMID:
27981616
47.

Cytotoxic T Cells and Granzyme B Associated with Improved Colorectal Cancer Survival in a Prospective Cohort of Older Women.

Prizment AE, Vierkant RA, Smyrk TC, Tillmans LS, Nelson HH, Lynch CF, Pengo T, Thibodeau SN, Church TR, Cerhan JR, Anderson KE, Limburg PJ.

Cancer Epidemiol Biomarkers Prev. 2017 Apr;26(4):622-631. doi: 10.1158/1055-9965.EPI-16-0641. Epub 2016 Dec 15.

48.

Development of a Microscopic Colitis Disease Activity Index: a prospective cohort study.

Cotter TG, Binder M, Loftus EV Jr, Abboud R, McNally MA, Smyrk TC, Tremaine WJ, Sandborn WJ, Pardi DS.

Gut. 2018 Mar;67(3):441-446. doi: 10.1136/gutjnl-2016-313051. Epub 2016 Dec 13.

PMID:
27965284
49.

Phase I/II Randomized Trial of Sorafenib and Bevacizumab as First-Line Therapy in Patients with Locally Advanced or Metastatic Hepatocellular Carcinoma: North Central Cancer Treatment Group Trial N0745 (Alliance).

Hubbard JM, Mahoney MR, Loui WS, Roberts LR, Smyrk TC, Gatalica Z, Borad M, Kumar S, Alberts SR.

Target Oncol. 2017 Apr;12(2):201-209. doi: 10.1007/s11523-016-0467-0.

50.

The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD).

Sarmento OF, Svingen PA, Xiong Y, Sun Z, Bamidele AO, Mathison AJ, Smyrk TC, Nair AA, Gonzalez MM, Sagstetter MR, Baheti S, McGovern DP, Friton JJ, Papadakis KA, Gautam G, Xavier RJ, Urrutia RA, Faubion WA.

J Biol Chem. 2017 Jan 13;292(2):706-722. doi: 10.1074/jbc.M116.749663. Epub 2016 Dec 1.

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