Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 54


Deubiquitination of phosphoribosyl-ubiquitin conjugates by phosphodiesterase-domain-containing Legionella effectors.

Wan M, Sulpizio AG, Akturk A, Beck WHJ, Lanz M, Faça VM, Smolka MB, Vogel JP, Mao Y.

Proc Natl Acad Sci U S A. 2019 Nov 5. pii: 201916287. doi: 10.1073/pnas.1916287116. [Epub ahead of print]


Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ.

Sulpizio A, Minelli ME, Wan M, Burrowes PD, Wu X, Sanford EJ, Shin JH, Williams BC, Goldberg ML, Smolka MB, Mao Y.

Elife. 2019 Nov 4;8. pii: e51162. doi: 10.7554/eLife.51162. [Epub ahead of print]


Activity of a ubiquitin ligase adaptor is regulated by disordered insertions in its arrestin domain.

Baile MG, Guiney EL, Sanford EJ, MacGurn JA, Smolka MB, Emr SD.

Mol Biol Cell. 2019 Oct 16:mbcE19080451. doi: 10.1091/mbc.E19-08-0451. [Epub ahead of print]


DNA damage kinase signaling: checkpoint and repair at 30 years.

Lanz MC, Dibitetto D, Smolka MB.

EMBO J. 2019 Sep 16;38(18):e101801. doi: 10.15252/embj.2019101801. Epub 2019 Aug 8. Review.


Mec1ATR Autophosphorylation and Ddc2ATRIP Phosphorylation Regulates DNA Damage Checkpoint Signaling.

Memisoglu G, Lanz MC, Eapen VV, Jordan JM, Lee K, Smolka MB, Haber JE.

Cell Rep. 2019 Jul 23;28(4):1090-1102.e3. doi: 10.1016/j.celrep.2019.06.068.


Progranulin deficiency leads to reduced glucocerebrosidase activity.

Zhou X, Paushter DH, Pagan MD, Kim D, Nunez Santos M, Lieberman RL, Overkleeft HS, Sun Y, Smolka MB, Hu F.

PLoS One. 2019 Jul 10;14(7):e0212382. doi: 10.1371/journal.pone.0212382. eCollection 2019.


PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling.

Shami Shah A, Batrouni AG, Kim D, Punyala A, Cao W, Han C, Goldberg ML, Smolka MB, Baskin JM.

Cell Rep. 2019 May 14;27(7):2157-2170.e8. doi: 10.1016/j.celrep.2019.04.060.


Next-Generation Sequencing Enables Spatiotemporal Resolution of Human Centromere Replication Timing.

Massey DJ, Kim D, Brooks KE, Smolka MB, Koren A.

Genes (Basel). 2019 Apr 2;10(4). pii: E269. doi: 10.3390/genes10040269.


ATR-mediated proteome remodeling is a major determinant of homologous recombination capacity in cancer cells.

Kim D, Liu Y, Oberly S, Freire R, Smolka MB.

Nucleic Acids Res. 2018 Sep 19;46(16):8311-8325. doi: 10.1093/nar/gky625.


Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling.

Lanz MC, Oberly S, Sanford EJ, Sharma S, Chabes A, Smolka MB.

Genes Dev. 2018 Jun 1;32(11-12):822-835. doi: 10.1101/gad.308148.117. Epub 2018 Jun 13.


Quantitative Analysis of DNA Damage Signaling Responses to Chemical and Genetic Perturbations.

Bastos de Oliveira FM, Kim D, Lanz M, Smolka MB.

Methods Mol Biol. 2018;1672:645-660. doi: 10.1007/978-1-4939-7306-4_42.


TOPBP1Dpb11 plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1Rad9.

Liu Y, Cussiol JR, Dibitetto D, Sims JR, Twayana S, Weiss RS, Freire R, Marini F, Pellicioli A, Smolka MB.

J Cell Biol. 2017 Mar 6;216(3):623-639. doi: 10.1083/jcb.201607031. Epub 2017 Feb 22.


PERK inhibits DNA replication during the Unfolded Protein Response via Claspin and Chk1.

Cabrera E, Hernández-Pérez S, Koundrioukoff S, Debatisse M, Kim D, Smolka MB, Freire R, Gillespie DA.

Oncogene. 2017 Feb 2;36(5):678-686. doi: 10.1038/onc.2016.239. Epub 2016 Jul 4.


The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway.

Sullivan PM, Zhou X, Robins AM, Paushter DH, Kim D, Smolka MB, Hu F.

Acta Neuropathol Commun. 2016 May 18;4(1):51. doi: 10.1186/s40478-016-0324-5.


Slx4 scaffolding in homologous recombination and checkpoint control: lessons from yeast.

Cussiol JR, Dibitetto D, Pellicioli A, Smolka MB.

Chromosoma. 2017 Feb;126(1):45-58. doi: 10.1007/s00412-016-0600-y. Epub 2016 May 10. Review.


TOPBP1 takes RADical command in recombinational DNA repair.

Liu Y, Smolka MB.

J Cell Biol. 2016 Feb 1;212(3):263-6. doi: 10.1083/jcb.201601028. Epub 2016 Jan 25.


Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation.

Bai G, Smolka MB, Schimenti JC.

PLoS Genet. 2016 Jan 14;12(1):e1005787. doi: 10.1371/journal.pgen.1005787. eCollection 2016 Jan.


Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.

Dibitetto D, Ferrari M, Rawal CC, Balint A, Kim T, Zhang Z, Smolka MB, Brown GW, Marini F, Pellicioli A.

Nucleic Acids Res. 2016 Jan 29;44(2):669-82. doi: 10.1093/nar/gkv1080. Epub 2015 Oct 20.


Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.

Zhou X, Sun L, Bastos de Oliveira F, Qi X, Brown WJ, Smolka MB, Sun Y, Hu F.

J Cell Biol. 2015 Sep 14;210(6):991-1002. doi: 10.1083/jcb.201502029.


Termination of Replication Stress Signaling via Concerted Action of the Slx4 Scaffold and the PP4 Phosphatase.

Jablonowski CM, Cussiol JR, Oberly S, Yimit A, Balint A, Kim T, Zhang Z, Brown GW, Smolka MB.

Genetics. 2015 Nov;201(3):937-49. doi: 10.1534/genetics.115.181479. Epub 2015 Sep 11.


Primary Structure of a Trypsin Inhibitor (Copaifera langsdorffii Trypsin Inhibitor-1) Obtained from C. langsdorffii Seeds.

Silva JA, Pompeu DG, Smolka MB, Gozzo FC, Comar M Jr, Eberlin MN, Granjeiro PA, Marangoni S.

J Biomol Tech. 2015 Sep;26(3):90-102. doi: 10.7171/jbt.15-2603-002.


Assembly of Slx4 signaling complexes behind DNA replication forks.

Balint A, Kim T, Gallo D, Cussiol JR, Bastos de Oliveira FM, Yimit A, Ou J, Nakato R, Gurevich A, Shirahige K, Smolka MB, Zhang Z, Brown GW.

EMBO J. 2015 Aug 13;34(16):2182-97. doi: 10.15252/embj.201591190. Epub 2015 Jun 25.


Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions.

Cussiol JR, Jablonowski CM, Yimit A, Brown GW, Smolka MB.

EMBO J. 2015 Jun 12;34(12):1704-17. doi: 10.15252/embj.201490834. Epub 2015 Apr 20.


Phosphoproteomics reveals distinct modes of Mec1/ATR signaling during DNA replication.

Bastos de Oliveira FM, Kim D, Cussiol JR, Das J, Jeong MC, Doerfler L, Schmidt KH, Yu H, Smolka MB.

Mol Cell. 2015 Mar 19;57(6):1124-1132. doi: 10.1016/j.molcel.2015.01.043. Epub 2015 Mar 5. Erratum in: Mol Cell. 2015 Apr 2;58(1):194.


A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.

Wei X, Das J, Fragoza R, Liang J, Bastos de Oliveira FM, Lee HR, Wang X, Mort M, Stenson PD, Cooper DN, Lipkin SM, Smolka MB, Yu H.

PLoS Genet. 2014 Dec 11;10(12):e1004819. doi: 10.1371/journal.pgen.1004819. eCollection 2014 Dec.


The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling.

Hsu F, Luo X, Qiu J, Teng YB, Jin J, Smolka MB, Luo ZQ, Mao Y.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10538-43. doi: 10.1073/pnas.1402605111. Epub 2014 Jul 8.


Identification of DNA damage checkpoint-dependent protein interactions in Saccharomyces cerevisiae using quantitative mass spectrometry.

de Oliveira FM, Smolka MB.

Methods Mol Biol. 2014;1156:251-63. doi: 10.1007/978-1-4939-0685-7_17.


Interactome analysis reveals ezrin can adopt multiple conformational states.

Viswanatha R, Wayt J, Ohouo PY, Smolka MB, Bretscher A.

J Biol Chem. 2013 Dec 6;288(49):35437-51. doi: 10.1074/jbc.M113.505669. Epub 2013 Oct 22.


The many roads to checkpoint activation.

Ohouo PY, Smolka MB.

Cell Cycle. 2012 Dec 15;11(24):4495. doi: 10.4161/cc.22933. Epub 2012 Dec 6. No abstract available.


Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells.

Viswanatha R, Ohouo PY, Smolka MB, Bretscher A.

J Cell Biol. 2012 Dec 10;199(6):969-84. doi: 10.1083/jcb.201207047. Epub 2012 Dec 3.


DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9.

Ohouo PY, Bastos de Oliveira FM, Liu Y, Ma CJ, Smolka MB.

Nature. 2013 Jan 3;493(7430):120-4. doi: 10.1038/nature11658. Epub 2012 Nov 18.


The checkpoint transcriptional response: make sure to turn it off once you are satisfied.

Smolka MB, Bastos de Oliveira FM, Harris MR, de Bruin RA.

Cell Cycle. 2012 Sep 1;11(17):3166-74. doi: 10.4161/cc.21197. Epub 2012 Aug 16.


DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1.

Travesa A, Kuo D, de Bruin RA, Kalashnikova TI, Guaderrama M, Thai K, Aslanian A, Smolka MB, Yates JR 3rd, Ideker T, Wittenberg C.

EMBO J. 2012 Apr 4;31(7):1811-22. doi: 10.1038/emboj.2012.28. Epub 2012 Feb 14.


Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes.

Bastos de Oliveira FM, Harris MR, Brazauskas P, de Bruin RA, Smolka MB.

EMBO J. 2012 Apr 4;31(7):1798-810. doi: 10.1038/emboj.2012.27. Epub 2012 Feb 14.


TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor.

MacGurn JA, Hsu PC, Smolka MB, Emr SD.

Cell. 2011 Nov 23;147(5):1104-17. doi: 10.1016/j.cell.2011.09.054.


A touching moment for Smc5/6: from ssDNA binding to repair.

Ohouo PY, Smolka MB.

Cell Cycle. 2011 Apr 15;10(8):1190-1. Epub 2011 Apr 15. No abstract available.


DNA damage signaling recruits the Rtt107-Slx4 scaffolds via Dpb11 to mediate replication stress response.

Ohouo PY, Bastos de Oliveira FM, Almeida BS, Smolka MB.

Mol Cell. 2010 Jul 30;39(2):300-6. doi: 10.1016/j.molcel.2010.06.019.


Whi5 regulation by site specific CDK-phosphorylation in Saccharomyces cerevisiae.

Wagner MV, Smolka MB, de Bruin RA, Zhou H, Wittenberg C, Dowdy SF.

PLoS One. 2009;4(1):e4300. doi: 10.1371/journal.pone.0004300. Epub 2009 Jan 28.


Phosphorylation-specific MS/MS scoring for rapid and accurate phosphoproteome analysis.

Payne SH, Yau M, Smolka MB, Tanner S, Zhou H, Bafna V.

J Proteome Res. 2008 Aug;7(8):3373-81. doi: 10.1021/pr800129m. Epub 2008 Jun 19.


Impact of phosphorylation and phosphorylation-null mutants on the activity and deamination specificity of activation-induced cytidine deaminase.

Pham P, Smolka MB, Calabrese P, Landolph A, Zhang K, Zhou H, Goodman MF.

J Biol Chem. 2008 Jun 20;283(25):17428-39. doi: 10.1074/jbc.M802121200. Epub 2008 Apr 16.


A multidimensional chromatography technology for in-depth phosphoproteome analysis.

Albuquerque CP, Smolka MB, Payne SH, Bafna V, Eng J, Zhou H.

Mol Cell Proteomics. 2008 Jul;7(7):1389-96. doi: 10.1074/mcp.M700468-MCP200. Epub 2008 Apr 11.


Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases.

Smolka MB, Albuquerque CP, Chen SH, Zhou H.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10364-9. Epub 2007 Jun 11.


Absence of classical heat shock response in the citrus pathogen Xylella fastidiosa.

Martins-de-Souza D, Astua-Monge G, Coletta-Filho HD, Winck FV, Baldasso PA, de Oliveira BM, Marangoni S, Machado MA, Novello JC, Smolka MB.

Curr Microbiol. 2007 Feb;54(2):119-23. Epub 2007 Jan 5. Erratum in: Curr Microbiol. 2009 Sep;59(3):362. Martins, Daniel [corrected to Martins-de-Souza, Daniel].


An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth.

Smolka MB, Chen SH, Maddox PS, Enserink JM, Albuquerque CP, Wei XX, Desai A, Kolodner RD, Zhou H.

J Cell Biol. 2006 Dec 4;175(5):743-53. Epub 2006 Nov 27.


Checkpoint proteins control morphogenetic events during DNA replication stress in Saccharomyces cerevisiae.

Enserink JM, Smolka MB, Zhou H, Kolodner RD.

J Cell Biol. 2006 Dec 4;175(5):729-41. Epub 2006 Nov 27.


Mechanism of Dun1 activation by Rad53 phosphorylation in Saccharomyces cerevisiae.

Chen SH, Smolka MB, Zhou H.

J Biol Chem. 2007 Jan 12;282(2):986-95. Epub 2006 Nov 17.


Comparative analysis of two-dimensional electrophoresis maps (2-DE) of Helicobacter pylori from Brazilian patients with chronic gastritis and duodenal ulcer: a preliminary report.

Pereira DR, Martins D, Winck FV, Smolka MB, Nishimura NF, Rabelo-Gonçalves EM, Hara NH, Marangoni S, Zeitune JM, Novello JC.

Rev Inst Med Trop Sao Paulo. 2006 May-Jun;48(3):175-7. Epub 2006 Jul 5.


Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag.

Smolka MB, Albuquerque CP, Chen SH, Schmidt KH, Wei XX, Kolodner RD, Zhou H.

Mol Cell Proteomics. 2005 Sep;4(9):1358-69. Epub 2005 Jun 22.


Novel protein from Labramia bojeri A. DC. seeds homologue to Kunitz-type trypsin inhibitor with lectin-like properties.

Macedo ML, Freire Md, Martins LT, Martinez DS, Gomes VM, Smolka MB, Toyama MH, Marangoni S, Coelho LC.

J Agric Food Chem. 2004 Dec 15;52(25):7548-54.


Proteome analysis of the plant pathogen Xylella fastidiosa reveals major cellular and extracellular proteins and a peculiar codon bias distribution.

Smolka MB, Martins-de-Souza D, Winck FV, Santoro CE, Castellari RR, Ferrari F, Brum IJ, Galembeck E, Della Coletta Filho H, Machado MA, Marangoni S, Novello JC.

Proteomics. 2003 Feb;3(2):224-37. Erratum in: Proteomics. 2009 Mar 5;9(5):1416. Martins, Daniel [corrected to Martins-de-Souza, Daniel].


Supplemental Content

Loading ...
Support Center