Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 46

1.

Upfront Genotyping of DPYD*2A to Individualize Fluoropyrimidine Therapy: A Safety and Cost Analysis.

Deenen MJ, Meulendijks D, Cats A, Sechterberger MK, Severens JL, Boot H, Smits PH, Rosing H, Mandigers CM, Soesan M, Beijnen JH, Schellens JH.

J Clin Oncol. 2016 Jan 20;34(3):227-34. doi: 10.1200/JCO.2015.63.1325. Epub 2015 Nov 16.

PMID:
26573078
2.

HPV-negative squamous cell carcinoma of the anal canal is unresponsive to standard treatment and frequently carries disruptive mutations in TP53.

Meulendijks D, Tomasoa NB, Dewit L, Smits PH, Bakker R, van Velthuysen ML, Rosenberg EH, Beijnen JH, Schellens JH, Cats A.

Br J Cancer. 2015 Apr 14;112(8):1358-66. doi: 10.1038/bjc.2015.20.

3.

Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy.

Joerger M, Huitema AD, Boot H, Cats A, Doodeman VD, Smits PH, Vainchtein L, Rosing H, Meijerman I, Zueger M, Meulendijks D, Cerny TD, Beijnen JH, Schellens JH.

Cancer Chemother Pharmacol. 2015 Apr;75(4):763-72. doi: 10.1007/s00280-015-2698-7. Epub 2015 Feb 13.

PMID:
25677447
4.

Multi-centre evaluation of real-time multiplex PCR for detection of carbapenemase genes OXA-48, VIM, IMP, NDM and KPC.

van der Zee A, Roorda L, Bosman G, Fluit AC, Hermans M, Smits PH, van der Zanden AG, Te Witt R, Bruijnesteijn van Coppenraet LE, Cohen Stuart J, Ossewaarde JM.

BMC Infect Dis. 2014 Jan 14;14:27. doi: 10.1186/1471-2334-14-27.

5.

RT-PCR detection of respiratory pathogens in newborn children admitted to a neonatal medium care unit.

Smit PM, Pronk SM, Kaandorp JC, Weijer O, Lauw FN, Smits PH, Claas EC, Mulder JW, Beijnen JH, Brandjes DP.

Pediatr Res. 2013 Mar;73(3):355-61. doi: 10.1038/pr.2012.176. Epub 2012 Nov 30.

PMID:
23202720
6.

Germline polymorphisms in patients with advanced nonsmall cell lung cancer receiving first-line platinum-gemcitabine chemotherapy: a prospective clinical study.

Joerger M, Burgers SA, Baas P, Smit EF, Haitjema TJ, Bard MP, Doodeman VD, Smits PH, Vincent A, Huitema AD, Beijnen JH, Schellens JH.

Cancer. 2012 May 1;118(9):2466-75. doi: 10.1002/cncr.26562. Epub 2011 Sep 28.

7.

Characterization of 2009 H1N1 pandemic influenza in a population of Dutch children with influenza-like signs and symptoms.

Smit PM, Bongers KM, Kuiper RJ, von Rosenstiel IA, Smits PH, Brandjes DP.

Acta Paediatr. 2012 Jan;101(1):67-72. doi: 10.1111/j.1651-2227.2011.02406.x. Epub 2011 Jul 27.

PMID:
21767303
8.

Low attack rate of novel influenza A (H1N1) virus infection among healthcare workers: a prospective study in a setting with an elaborated containment plan.

Smit PM, Mulder JW, Ahdi M, Gerritsen R, Darma S, Smits PH, Roggeveen C, van Gorp EC, Rimmelzwaan GF, Brandjes DP.

Int Arch Occup Environ Health. 2012 Feb;85(2):163-70. doi: 10.1007/s00420-011-0652-5. Epub 2011 Jun 4.

PMID:
21643772
9.

Gene polymorphisms, pharmacokinetics, and hematological toxicity in advanced non-small-cell lung cancer patients receiving cisplatin/gemcitabine.

Joerger M, Burgers JA, Baas P, Doodeman VD, Smits PH, Jansen RS, Vainchtein LD, Rosing H, Huitema AD, Beijnen JH, Schellens JH.

Cancer Chemother Pharmacol. 2012 Jan;69(1):25-33. doi: 10.1007/s00280-011-1670-4. Epub 2011 May 18.

PMID:
21590444
10.

Relationship between single nucleotide polymorphisms and haplotypes in DPYD and toxicity and efficacy of capecitabine in advanced colorectal cancer.

Deenen MJ, Tol J, Burylo AM, Doodeman VD, de Boer A, Vincent A, Guchelaar HJ, Smits PH, Beijnen JH, Punt CJ, Schellens JH, Cats A.

Clin Cancer Res. 2011 May 15;17(10):3455-68. doi: 10.1158/1078-0432.CCR-10-2209. Epub 2011 Apr 15.

11.

Adult outpatient experience of the 2009 H1N1 pandemic: clinical course, pathogens, and evaluation of case definitions.

Smit PM, Limper M, van Gorp EC, Smits PH, Beijnen JH, Brandjes DP, Mulder JW.

J Infect. 2011 May;62(5):371-8. doi: 10.1016/j.jinf.2011.03.005. Epub 2011 Mar 21.

PMID:
21420427
12.

Procalcitonin in children with suspected novel influenza A (H1N1) infection.

Limper M, Smit PM, Bongers KM, van Zanten AP, Smits PH, Brandjes DP, Mulder JW, von Rosenstiel IA, van Gorp EC.

J Infect. 2010 Oct;61(4):351-3. doi: 10.1016/j.jinf.2010.07.005. Epub 2010 Jul 16. No abstract available.

PMID:
20638412
13.

Prolonged exposure to tenofovir monotherapy 1 month after treatment discontinuation because of tenofovir-related renal failure.

Ter Heine R, Huitema AD, Jansen RS, Smits PH, van Gorp EC, Wagenaar JF, Beijnen JH, Mulder JW.

Antivir Ther. 2009;14(2):299-301.

PMID:
19430105
14.

Recurrent increase of liver enzymes in a human immunodeficiency virus infected male with recent acute hepatitis B infection.

van Es J, Wagenaar JF, Smits PH, Depla AC, van Gorp EC, Mulder JW; UK Clinical Virology Network.

J Clin Virol. 2009 Apr;44(4):vi; discussion I. No abstract available.

PMID:
19338073
15.

Effect of HIV viral load, CD4 cell count and antiretroviral therapy on human papillomavirus prevalence in urine samples of HIV-infected men.

Jong E, van Gorp EC, Mulder JW, Tol A, Smits PH.

Int J STD AIDS. 2009 Apr;20(4):262-4. doi: 10.1258/ijsa.2008.008359.

PMID:
19304972
16.

Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.

Ekhart C, Doodeman VD, Rodenhuis S, Smits PH, Beijnen JH, Huitema AD.

Br J Clin Pharmacol. 2009 Jan;67(1):50-60. doi: 10.1111/j.1365-2125.2008.03321.x. Epub 2008 Nov 17.

17.

Relations between polymorphisms in drug-metabolising enzymes and toxicity of chemotherapy with cyclophosphamide, thiotepa and carboplatin.

Ekhart C, Rodenhuis S, Smits PH, Beijnen JH, Huitema AD.

Pharmacogenet Genomics. 2008 Nov;18(11):1009-15. doi: 10.1097/FPC.0b013e328313aaa4.

PMID:
18854779
18.

An overview of the relations between polymorphisms in drug metabolising enzymes and drug transporters and survival after cancer drug treatment.

Ekhart C, Rodenhuis S, Smits PH, Beijnen JH, Huitema AD.

Cancer Treat Rev. 2009 Feb;35(1):18-31. doi: 10.1016/j.ctrv.2008.07.003. Epub 2008 Sep 3. Review.

PMID:
18771857
19.

Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide.

Ekhart C, Doodeman VD, Rodenhuis S, Smits PH, Beijnen JH, Huitema AD.

Pharmacogenet Genomics. 2008 Jun;18(6):515-23. doi: 10.1097/FPC.0b013e3282fc9766.

PMID:
18496131
20.

The prevalence of human papillomavirus (HPV) infection in paired urine and cervical smear samples of HIV-infected women.

Jong E, Mulder JW, van Gorp EC, Wagenaar JK, Derksen J, Westerga J, Tol A, Smits PH.

J Clin Virol. 2008 Feb;41(2):111-5.

PMID:
18354821
21.

Aberrant Epstein-Barr virus persistence in HIV carriers is characterized by anti-Epstein-Barr virus IgA and high cellular viral loads with restricted transcription.

Stevens SJ, Smits PH, Verkuijlen SA, Rockx DA, van Gorp EC, Mulder JW, Middeldorp JM.

AIDS. 2007 Oct 18;21(16):2141-9.

PMID:
18090040
22.

Rapid detection of the DPYD IVS14+1G>A mutation for screening patients to prevent fluorouracil-related toxicity.

Bosch TM, Bakker R, Schellens JH, Cats A, Smits PH, Beijnen JH.

Mol Diagn Ther. 2007;11(2):105-8.

PMID:
17397246
23.

Pharmacogenetic screening of the gene deletion and duplications of CYP2D6.

Meijerman I, Sanderson LM, Smits PH, Beijnen JH, Schellens JH.

Drug Metab Rev. 2007;39(1):45-60. Review.

PMID:
17364880
24.

ABCB1 genotypes and haplotypes in patients with dementia and age-matched non-demented control patients.

Frankfort SV, Doodeman VD, Bakker R, Tulner LR, van Campen JP, Smits PH, Beijnen JH.

Mol Neurodegener. 2006 Sep 25;1:13.

25.

Novel deoxycytidine kinase gene polymorphisms: a population screening study in Caucasian healthy volunteers.

Joerger M, Bosch TM, Doodeman VD, Beijnen JH, Smits PH, Schellens JH.

Eur J Clin Pharmacol. 2006 Aug;62(8):681-4. Epub 2006 Jun 24.

PMID:
16799820
26.

Pharmacogenetic screening for polymorphisms in drug-metabolizing enzymes and drug transporters in a Dutch population.

Bosch TM, Doodeman VD, Smits PH, Meijerman I, Schellens JH, Beijnen JH.

Mol Diagn Ther. 2006;10(3):175-85.

PMID:
16771603
27.

Screening for polymorphisms in the PXR gene in a Dutch population.

Bosch TM, Deenen M, Pruntel R, Smits PH, Schellens JH, Beijnen JH, Meijerman I.

Eur J Clin Pharmacol. 2006 May;62(5):395-9. Epub 2006 Mar 28.

PMID:
16568343
28.

High prevalence of human papillomavirus infections in urine samples from human immunodeficiency virus-infected men.

Smits PH, Bakker R, Jong E, Mulder JW, Meenhorst PL, Kleter B, van Doorn LJ, Quint WG.

J Clin Microbiol. 2005 Dec;43(12):5936-9.

29.

Detection of single nucleotide polymorphisms in the ABCG2 gene in a Dutch population.

Bosch TM, Kjellberg LM, Bouwers A, Koeleman BP, Schellens JH, Beijnen JH, Smits PH, Meijerman I.

Am J Pharmacogenomics. 2005;5(2):123-31.

PMID:
15813675
30.

The role of platelets in venous thrombosis: a patient with Glanzmann's thrombasthenia and a factor V Leiden mutation suffering from deep venous thrombosis.

Ten Cate H, Brandjes DP, Smits PH, van Mourik JA.

J Thromb Haemost. 2003 Feb;1(2):394-5. No abstract available.

31.

Detection of late pp67-mRNA by NASBA in peripheral blood for the diagnosis of human cytomegalovirus disease in AIDS patients.

Blank BS, Meenhorst PL, Pauw W, Mulder JW, van Dijk WC, Smits PH, Roeles F, Middeldorp JM, Lange JM.

J Clin Virol. 2002 Jul;25(1):29-38.

PMID:
12126719
32.

High Epstein-Barr virus (EBV) DNA loads in HIV-infected patients: correlation with antiretroviral therapy and quantitative EBV serology.

Stevens SJ, Blank BS, Smits PH, Meenhorst PL, Middeldorp JM.

AIDS. 2002 May 3;16(7):993-1001.

PMID:
11953465
33.

Comparative analysis of human papillomavirus infections in cervical scrapes and biopsy specimens by general SPF(10) PCR and HPV genotyping.

Quint WG, Scholte G, van Doorn LJ, Kleter B, Smits PH, Lindeman J.

J Pathol. 2001 May;194(1):51-8.

PMID:
11329141
34.

Automated, simultaneous detection of the factor V Leiden and prothrombin (G20210A) variants using multiplex PCR and a line probe assay.

Leyte A, Smits PH, van Straalen JP, van Doorn LJ, Quint WG.

Thromb Haemost. 2000 Feb;83(2):354-5. No abstract available.

PMID:
10739403
35.

Biological activity of SeMNPV, AcMNPV, and three AcMNPV deletion mutants against Spodoptera exigua larvae (Lepidoptera: noctuidae).

Bianchi FJ, Snoeijing I, van der Werf W, Mans RM, Smits PH, Vlak JM.

J Invertebr Pathol. 2000 Jan;75(1):28-35.

PMID:
10631054
36.

The N-terminal transactivation domain of ATF2 is a target for the co-operative activation of the c-jun promoter by p300 and 12S E1A.

Duyndam MC, van Dam H, Smits PH, Verlaan M, van der Eb AJ, Zantema A.

Oncogene. 1999 Apr 8;18(14):2311-21.

37.
38.

Polyclonal Antisera To Distinguish Strains and Form Variants of Photorhabdus (Xenorhabdus) luminescens.

Gerritsen L, van der Wolf JM, van Vuurde J, Ehlers R, Krasomil-Osterfel KC, Smits PH.

Appl Environ Microbiol. 1995 Jan;61(1):284-9.

39.

Complete DNA sequence of yeast chromosome II.

Feldmann H, Aigle M, Aljinovic G, André B, Baclet MC, Barthe C, Baur A, Bécam AM, Biteau N, Boles E, Brandt T, Brendel M, Brückner M, Bussereau F, Christiansen C, Contreras R, Crouzet M, Cziepluch C, Démolis N, Delaveau T, Doignon F, Domdey H, Düsterhus S, Dubois E, Dujon B, El Bakkoury M, Entian KD, Feurmann M, Fiers W, Fobo GM, Fritz C, Gassenhuber H, Glandsdorff N, Goffeau A, Grivell LA, de Haan M, Hein C, Herbert CJ, Hollenberg CP, Holmstrøm K, Jacq C, Jacquet M, Jauniaux JC, Jonniaux JL, Kallesøe T, Kiesau P, Kirchrath L, Kötter P, Korol S, Liebl S, Logghe M, Lohan AJ, Louis EJ, Li ZY, Maat MJ, Mallet L, Mannhaupt G, Messenguy F, Miosga T, Molemans F, Müller S, Nasr F, Obermaier B, Perea J, Piérard A, Piravandi E, Pohl FM, Pohl TM, Potier S, Proft M, Purnelle B, Ramezani Rad M, Rieger M, Rose M, Schaaff-Gerstenschläger I, Scherens B, Schwarzlose C, Skala J, Slonimski PP, Smits PH, Souciet JL, Steensma HY, Stucka R, Urrestarazu A, van der Aart QJ, van Dyck L, Vassarotti A, Vetter I, Vierendeels F, Vissers S, Wagner G, de Wergifosse P, Wolfe KH, Zagulski M, Zimmermann FK, Mewes HW, Kleine K.

EMBO J. 1994 Dec 15;13(24):5795-809.

41.
42.

The 55 kDa regulatory subunit of protein phosphatase 2A plays a role in the activation of the HPV16 long control region in human cells with a deletion in the short arm of chromosome 11.

Smits PH, Smits HL, Minnaar RP, Hemmings BA, Mayer-Jaekel RE, Schuurman R, van der Noordaa J, ter Schegget J.

EMBO J. 1992 Dec;11(12):4601-6.

43.
44.

Characterization of form variants of Xenorhabdus luminescens.

Gerritsen LJ, de Raay G, Smits PH.

Appl Environ Microbiol. 1992 Jun;58(6):1975-9.

46.

Massive mediastinal hemorrhage following treatment of hyperthyroidism with radioactive iodine.

Prenger KB, Poeschmann PH, Smits PH, Eygelaar A.

Thorac Cardiovasc Surg. 1984 Apr;32(2):122-3.

PMID:
6204408

Supplemental Content

Loading ...
Support Center