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Preoperative Ultrasound Assessment of Regional Lymph Nodes in Melanoma Patients Does not Provide Reliable Nodal Staging: Results from a Large Multicenter Trial.

Thompson JF, Haydu LE, Uren RF, Andtbacka RH, Zager JS, Beitsch PD, Agnese DM, Mozzillo N, Testori A, Bowles TL, Hoekstra HJ, Kelley MC, Sussman J, Schneebaum S, Smithers BM, McKinnon G, Hsueh E, Jacobs L, Schultz E, Reintgen D, Kane JM, Friedman EB, Wang H, Van Kreuningen L, Schiller V, Elashoff DA, Elashoff R, Cochran AJ, Stern S, Faries MB; MSLT-II Trial Group.

Ann Surg. 2019 Jun 7. doi: 10.1097/SLA.0000000000003405. [Epub ahead of print]


Risk of Melanoma Recurrence After Diagnosis of a High-Risk Primary Tumor.

von Schuckmann LA, Hughes MCB, Ghiasvand R, Malt M, van der Pols JC, Beesley VL, Khosrotehrani K, Smithers BM, Green AC.

JAMA Dermatol. 2019 May 1. doi: 10.1001/jamadermatol.2019.0440. [Epub ahead of print]


The Impact of Signet Ring Cell Differentiation on Outcome in Patients with Esophageal and Gastroesophageal Junction Adenocarcinoma.

van Hootegem SJM, Smithers BM, Gotley DC, Brosda S, Thomson IG, Thomas JM, Gartside M, van Lanschot JJB, Lagarde SM, Wijnhoven BPL, Barbour AP.

Ann Surg Oncol. 2019 Apr 2. doi: 10.1245/s10434-019-07322-x. [Epub ahead of print]


Conclusions from quality of life studies in patients with resected high-risk melanoma: one part of the full story.

Smithers BM.

Lancet Oncol. 2019 May;20(5):611-612. doi: 10.1016/S1470-2045(19)30176-7. Epub 2019 Mar 27. No abstract available.


Evaluation of the efficacy and toxicity of upper extremity isolated limb infusion chemotherapy for melanoma: An Australian multi-center study.

Kroon HM, Coventry BJ, Henderson MA, Barbour A, Serpell J, Smithers BM, Thompson JF.

Eur J Surg Oncol. 2019 May;45(5):832-837. doi: 10.1016/j.ejso.2019.02.026. Epub 2019 Feb 27.


A systematic review and meta-analysis of locoregional treatments for in-transit melanoma.

Read T, Lonne M, Sparks DS, David M, Wagels M, Schaider H, Soyer HP, Smithers BM.

J Surg Oncol. 2019 Jun;119(7):887-896. doi: 10.1002/jso.25400. Epub 2019 Feb 7.


Phenotypic and genotypic analysis of amelanotic and hypomelanotic melanoma patients.

Rayner JE, McMeniman EK, Duffy DL, De'Ambrosis B, Smithers BM, Jagirdar K, Lee KJ, Soyer HP, Sturm RA.

J Eur Acad Dermatol Venereol. 2019 Jun;33(6):1076-1083. doi: 10.1111/jdv.15446. Epub 2019 Mar 15.


Patterns of Failure Following Dose-escalated Chemoradiotherapy for Fluorodeoxyglucose Positron Emission Tomography Staged Squamous Cell Carcinoma of the Oesophagus.

Effeney R, Shaw T, Burmeister BH, Burmeister E, Harvey J, Mai GT, Thomas J, Barbour AP, Smithers BM, Pryor DI.

Clin Oncol (R Coll Radiol). 2018 Oct;30(10):642-649. doi: 10.1016/j.clon.2018.06.011. Epub 2018 Jul 14.


Sun protection behavior after diagnosis of high-risk primary melanoma and risk of a subsequent primary.

von Schuckmann LA, Wilson LF, Hughes MCB, Beesley VL, Janda M, van der Pols JC, Smithers BM, Khosrotehrani K, Green AC.

J Am Acad Dermatol. 2019 Jan;80(1):139-148.e4. doi: 10.1016/j.jaad.2018.06.068.


Multicentre factorial randomized clinical trial of perioperative immunonutrition versus standard nutrition for patients undergoing surgical resection of oesophageal cancer.

Mudge LA, Watson DI, Smithers BM, Isenring EA, Smith L, Jamieson GG; Australian Immunonutrition Study Group.

Br J Surg. 2018 Sep;105(10):1262-1272. doi: 10.1002/bjs.10923. Epub 2018 Jul 12.


MAGE-A3 immunotherapeutic as adjuvant therapy for patients with resected, MAGE-A3-positive, stage III melanoma (DERMA): a double-blind, randomised, placebo-controlled, phase 3 trial.

Dreno B, Thompson JF, Smithers BM, Santinami M, Jouary T, Gutzmer R, Levchenko E, Rutkowski P, Grob JJ, Korovin S, Drucis K, Grange F, Machet L, Hersey P, Krajsova I, Testori A, Conry R, Guillot B, Kruit WHJ, Demidov L, Thompson JA, Bondarenko I, Jaroszek J, Puig S, Cinat G, Hauschild A, Goeman JJ, van Houwelingen HC, Ulloa-Montoya F, Callegaro A, Dizier B, Spiessens B, Debois M, Brichard VG, Louahed J, Therasse P, Debruyne C, Kirkwood JM.

Lancet Oncol. 2018 Jul;19(7):916-929. doi: 10.1016/S1470-2045(18)30254-7. Epub 2018 Jun 13.


Neoadjuvant chemotherapy or chemoradiotherapy for adenocarcinoma of the esophagus.

Visser E, Edholm D, Smithers BM, Thomson IG, Burmeister BH, Walpole ET, Gotley DC, Joubert WL, Atkinson V, Mai T, Thomas JM, Barbour AP.

J Surg Oncol. 2018 Jun;117(8):1687-1696. doi: 10.1002/jso.25089. Epub 2018 May 28.


Survival of patients with early invasive melanoma down-staged under the new eighth edition of the American Joint Committee on Cancer staging system.

von Schuckmann LA, Hughes MCB, Lee R, Lorigan P, Khosrotehrani K, Smithers BM, Green AC.

J Am Acad Dermatol. 2019 Jan;80(1):272-274. doi: 10.1016/j.jaad.2018.04.017. Epub 2018 Apr 16. No abstract available.


Neoadjuvant therapy reduces cardiopulmunary function in patients undegoing oesophagectomy.

Thomson IG, Wallen MP, Hall A, Ferris R, Gotley DC, Barbour AP, Lee A, Thomas J, Smithers BM.

Int J Surg. 2018 May;53:86-92. doi: 10.1016/j.ijsu.2018.03.030. Epub 2018 Mar 16.


Intralesional PV-10 for the treatment of in-transit melanoma metastases-Results of a prospective, non-randomized, single center study.

Read TA, Smith A, Thomas J, David M, Foote M, Wagels M, Barbour A, Smithers BM.

J Surg Oncol. 2018 Mar;117(4):579-587. doi: 10.1002/jso.24921. Epub 2018 Mar 12.


In response to: Immigration is the most likely reason for the generational change in melanoma incidence in Queensland, Australia.

Aitken JF, Youlden DR, Baade PD, Soyer HP, Green AC, Smithers BM.

Int J Cancer. 2018 Aug 1;143(3):722-723. doi: 10.1002/ijc.31347. Epub 2018 Mar 12. No abstract available.


Generational shift in melanoma incidence and mortality in Queensland, Australia, 1995-2014.

Aitken JF, Youlden DR, Baade PD, Soyer HP, Green AC, Smithers BM.

Int J Cancer. 2018 Apr 15;142(8):1528-1535. doi: 10.1002/ijc.31141. Epub 2017 Nov 21.


Clustering of prevention behaviours in patients with high-risk primary melanoma.

Green AC, Hughes MCB, von Schuckmann LA, Khosrotehrani K, Smithers BM.

Psychooncology. 2018 May;27(5):1442-1449. doi: 10.1002/pon.4565. Epub 2017 Nov 7.


Whither melanoma in Australia?

Smithers BM, Dunn J, Soyer HP.

Med J Aust. 2017 Oct 16;207(8):330-331. No abstract available.


Protocol for the TIDAL Melanoma Study: topical imiquimod or diphenylcyclopropenone for the management of cutaneous in-transit melanoma metastases-a phase II, single centre, randomised, pilot study.

Read T, Webber S, Thomas J, Wagels M, Schaider H, Soyer HP, Smithers BM.

BMJ Open. 2017 Oct 6;7(10):e016816. doi: 10.1136/bmjopen-2017-016816.


Associations of Statins and Diabetes with Diagnosis of Ulcerated Cutaneous Melanoma.

von Schuckmann LA, Smith D, Hughes MCB, Malt M, van der Pols JC, Khosrotehrani K, Smithers BM, Green AC.

J Invest Dermatol. 2017 Dec;137(12):2599-2605. doi: 10.1016/j.jid.2017.07.836. Epub 2017 Aug 23.


Safety and Efficacy of Isolated Limb Infusion Chemotherapy for Advanced Locoregional Melanoma in Elderly Patients: An Australian Multicenter Study.

Kroon HM, Coventry BJ, Giles MH, Henderson MA, Speakman D, Wall M, Barbour A, Serpell J, Paddle P, Smithers BM, Thompson JF.

Ann Surg Oncol. 2017 Oct;24(11):3245-3251. doi: 10.1245/s10434-017-6046-5. Epub 2017 Aug 10.


Diphenylcyclopropenone for the treatment of cutaneous in-transit melanoma metastases - results of a prospective, non-randomized, single-centre study.

Read T, Webber S, Tan J, Wagels M, Schaider H, Soyer HP, Smithers BM.

J Eur Acad Dermatol Venereol. 2017 Dec;31(12):2030-2037. doi: 10.1111/jdv.14422. Epub 2017 Jul 13.


Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma.

Faries MB, Thompson JF, Cochran AJ, Andtbacka RH, Mozzillo N, Zager JS, Jahkola T, Bowles TL, Testori A, Beitsch PD, Hoekstra HJ, Moncrieff M, Ingvar C, Wouters MWJM, Sabel MS, Levine EA, Agnese D, Henderson M, Dummer R, Rossi CR, Neves RI, Trocha SD, Wright F, Byrd DR, Matter M, Hsueh E, MacKenzie-Ross A, Johnson DB, Terheyden P, Berger AC, Huston TL, Wayne JD, Smithers BM, Neuman HB, Schneebaum S, Gershenwald JE, Ariyan CE, Desai DC, Jacobs L, McMasters KM, Gesierich A, Hersey P, Bines SD, Kane JM, Barth RJ, McKinnon G, Farma JM, Schultz E, Vidal-Sicart S, Hoefer RA, Lewis JM, Scheri R, Kelley MC, Nieweg OE, Noyes RD, Hoon DSB, Wang HJ, Elashoff DA, Elashoff RM.

N Engl J Med. 2017 Jun 8;376(23):2211-2222. doi: 10.1056/NEJMoa1613210.


Use of support services in a sample of patients with high-risk primary melanomas in urban, regional and rural Queensland.

von Schuckmann LA, Smithers BM, Khosrotehrani K, Beesley VL, van der Pols JC, Hughes MB, Green AC.

Aust N Z J Public Health. 2017 Jun;41(3):315-319. doi: 10.1111/1753-6405.12662. Epub 2017 Mar 28.


TOPGEAR: A Randomized, Phase III Trial of Perioperative ECF Chemotherapy with or Without Preoperative Chemoradiation for Resectable Gastric Cancer: Interim Results from an International, Intergroup Trial of the AGITG, TROG, EORTC and CCTG.

Leong T, Smithers BM, Haustermans K, Michael M, Gebski V, Miller D, Zalcberg J, Boussioutas A, Findlay M, O'Connell RL, Verghis J, Willis D, Kron T, Crain M, Murray WK, Lordick F, Swallow C, Darling G, Simes J, Wong R.

Ann Surg Oncol. 2017 Aug;24(8):2252-2258. doi: 10.1245/s10434-017-5830-6. Epub 2017 Mar 23.


Results of a phase II, open-label, non-comparative study of intralesional PV-10 followed by radiotherapy for the treatment of in-transit or metastatic melanoma.

Foote M, Read T, Thomas J, Wagels M, Burmeister B, Smithers BM.

J Surg Oncol. 2017 Jun;115(7):891-897. doi: 10.1002/jso.24580. Epub 2017 Feb 23.


Outcome predictors in median arcuate ligament syndrome.

Ho KKF, Walker P, Smithers BM, Foster W, Nathanson L, O'Rourke N, Shaw I, McGahan T.

J Vasc Surg. 2017 Jun;65(6):1745-1752. doi: 10.1016/j.jvs.2016.11.040. Epub 2017 Feb 8.


Primary cutaneous melanoma of the scalp: Patterns of recurrence.

Sparks DS, Read T, Lonne M, Barbour AP, Wagels M, Bayley GJ, Smithers BM.

J Surg Oncol. 2017 Mar;115(4):449-454. doi: 10.1002/jso.24535. Epub 2016 Dec 30.


Worldwide Esophageal Cancer Collaboration: clinical staging data.

Rice TW, Apperson-Hansen C, DiPaola LM, Semple ME, Lerut TE, Orringer MB, Chen LQ, Hofstetter WL, Smithers BM, Rusch VW, Wijnhoven BP, Chen KN, Davies AR, D'Journo XB, Kesler KA, Luketich JD, Ferguson MK, Räsänen JV, van Hillegersberg R, Fang W, Durand L, Allum WH, Cecconello I, Cerfolio RJ, Pera M, Griffin SM, Burger R, Liu JF, Allen MS, Law S, Watson TJ, Darling GE, Scott WJ, Duranceau A, Denlinger CE, Schipper PH, Ishwaran H, Blackstone EH.

Dis Esophagus. 2016 Oct;29(7):707-714. doi: 10.1111/dote.12493.


Worldwide Esophageal Cancer Collaboration: neoadjuvant pathologic staging data.

Rice TW, Lerut TE, Orringer MB, Chen LQ, Hofstetter WL, Smithers BM, Rusch VW, van Lanschot J, Chen KN, Davies AR, D'Journo XB, Kesler KA, Luketich JD, Ferguson MK, Räsänen JV, van Hillegersberg R, Fang W, Durand L, Allum WH, Cecconello I, Cerfolio RJ, Pera M, Griffin SM, Burger R, Liu JF, Allen MS, Law S, Watson TJ, Darling GE, Scott WJ, Duranceau A, Denlinger CE, Schipper PH, Ishwaran H, Apperson-Hansen C, DiPaola LM, Semple ME, Blackstone EH.

Dis Esophagus. 2016 Oct;29(7):715-723. doi: 10.1111/dote.12513.


Worldwide Esophageal Cancer Collaboration: pathologic staging data.

Rice TW, Chen LQ, Hofstetter WL, Smithers BM, Rusch VW, Wijnhoven BP, Chen KL, Davies AR, D'Journo XB, Kesler KA, Luketich JD, Ferguson MK, Räsänen JV, van Hillegersberg R, Fang W, Durand L, Cecconello I, Allum WH, Cerfolio RJ, Pera M, Griffin SM, Burger R, Liu JF, Allen MS, Law S, Watson TJ, Darling GE, Scott WJ, Duranceau A, Denlinger CE, Schipper PH, Lerut TE, Orringer MB, Ishwaran H, Apperson-Hansen C, DiPaola LM, Semple ME, Blackstone EH.

Dis Esophagus. 2016 Oct;29(7):724-733. doi: 10.1111/dote.12520.


Variations in supportive care needs of patients after diagnosis of localised cutaneous melanoma: a 2-year follow-up study.

Beesley VL, Smithers BM, O'Rourke P, Janda M, Khosrotehrani K, Green AC.

Support Care Cancer. 2017 Jan;25(1):93-102. Epub 2016 Aug 25.


Long-term Health-related Quality of Life Following Esophagectomy: A Nonrandomized Comparison of Thoracoscopically Assisted and Open Surgery.

Barbour AP, Cormack OMM, Baker PJ, Hirst J, Krause L, Brosda S, Thomas JM, Blazeby JM, Thomson IG, Gotley DC, Smithers BM.

Ann Surg. 2017 Jun;265(6):1158-1165. doi: 10.1097/SLA.0000000000001899.


GSTP1 does not modify MC1R effects on melanoma risk.

Daley GM, Duffy DL, Pflugfelder A, Jagirdar K, Lee KJ, Yong XLH, Eigentler TK, Weide B, Smithers BM, Martin NG, Garbe C, Soyer HP, Sturm RA.

Exp Dermatol. 2017 Aug;26(8):730-733. doi: 10.1111/exd.13114. Epub 2017 Mar 23. No abstract available.


Assessment of morbidity following regional nodal dissection in the axilla and groin for metastatic melanoma.

Theodore JE, Frankel AJ, Thomas JM, Barbour AP, Bayley GJ, Allan CP, Wagels M, Smithers BM.

ANZ J Surg. 2017 Jan;87(1-2):44-48. doi: 10.1111/ans.13526. Epub 2016 Apr 21.


Molecular markers to complement sentinel node status in predicting survival in patients with high-risk locally invasive melanoma.

Rowe CJ, Tang F, Hughes MC, Rodero MP, Malt M, Lambie D, Barbour A, Hayward NK, Smithers BM, Green AC, Khosrotehrani K.

Int J Cancer. 2016 Aug 1;139(3):664-72. doi: 10.1002/ijc.30085. Epub 2016 Apr 4.


Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma.

Krause L, Nones K, Loffler KA, Nancarrow D, Oey H, Tang YH, Wayte NJ, Patch AM, Patel K, Brosda S, Manning S, Lampe G, Clouston A, Thomas J, Stoye J, Hussey DJ, Watson DI, Lord RV, Phillips WA, Gotley D, Smithers BM, Whiteman DC, Hayward NK, Grimmond SM, Waddell N, Barbour AP.

Carcinogenesis. 2016 Apr;37(4):356-65. doi: 10.1093/carcin/bgw018. Epub 2016 Feb 10.


Australian Multicenter Study of Isolated Limb Infusion for Melanoma.

Kroon HM, Coventry BJ, Giles MH, Henderson MA, Speakman D, Wall M, Barbour A, Serpell J, Paddle P, Coventry AG, Sullivan T, Smithers BM, Thompson JF.

Ann Surg Oncol. 2016 Apr;23(4):1096-103. doi: 10.1245/s10434-015-4969-2. Epub 2015 Nov 18.


Building a sustainable clinical academic workforce to meet the future healthcare needs of Australia and New Zealand: report from the first summit meeting.

Windsor J, Searle J, Hanney R, Chapman A, Grigg M, Choong P, Mackay A, Smithers BM, Churchill JA, Carney S, Smith JA, Wainer Z, Talley NJ, Gladman MA.

Intern Med J. 2015 Sep;45(9):965-71. doi: 10.1111/imj.12854.


Prospective study of patterns of surgical management in adults with primary cutaneous melanoma at high risk of spread, in Queensland, Australia.

Smithers BM, Hughes MC, Beesley VL, Barbour AP, Malt MK, Weedon D, Zonta MJ, Wood DJ, Triscott JA, Bayley GJ, Brown LJ, Allan CP, D'Arcy J, Williamson R, Khosrotehrani K, Green AC.

J Surg Oncol. 2015 Sep;112(4):359-65. doi: 10.1002/jso.24013. Epub 2015 Aug 27.


A systematic review of non-surgical treatments for lentigo maligna.

Read T, Noonan C, David M, Wagels M, Foote M, Schaider H, Soyer HP, Smithers BM.

J Eur Acad Dermatol Venereol. 2016 May;30(5):748-53. doi: 10.1111/jdv.13252. Epub 2015 Aug 24. Review.


Adjuvant lymph-node field radiotherapy versus observation only in patients with melanoma at high risk of further lymph-node field relapse after lymphadenectomy (ANZMTG 01.02/TROG 02.01): 6-year follow-up of a phase 3, randomised controlled trial.

Henderson MA, Burmeister BH, Ainslie J, Fisher R, Di Iulio J, Smithers BM, Hong A, Shannon K, Scolyer RA, Carruthers S, Coventry BJ, Babington S, Duprat J, Hoekstra HJ, Thompson JF.

Lancet Oncol. 2015 Sep;16(9):1049-1060. doi: 10.1016/S1470-2045(15)00187-4. Epub 2015 Jul 20.


TOPGEAR: a randomised phase III trial of perioperative ECF chemotherapy versus preoperative chemoradiation plus perioperative ECF chemotherapy for resectable gastric cancer (an international, intergroup trial of the AGITG/TROG/EORTC/NCIC CTG).

Leong T, Smithers BM, Michael M, Gebski V, Boussioutas A, Miller D, Simes J, Zalcberg J, Haustermans K, Lordick F, Schuhmacher C, Swallow C, Darling G, Wong R.

BMC Cancer. 2015 Jul 21;15:532. doi: 10.1186/s12885-015-1529-x.


Australian clinical practice guidelines for the diagnosis and management of Barrett's esophagus and early esophageal adenocarcinoma.

Whiteman DC, Appleyard M, Bahin FF, Bobryshev YV, Bourke MJ, Brown I, Chung A, Clouston A, Dickins E, Emery J, Eslick GD, Gordon LG, Grimpen F, Hebbard G, Holliday L, Hourigan LF, Kendall BJ, Lee EY, Levert-Mignon A, Lord RV, Lord SJ, Maule D, Moss A, Norton I, Olver I, Pavey D, Raftopoulos S, Rajendra S, Schoeman M, Singh R, Sitas F, Smithers BM, Taylor AC, Thomas ML, Thomson I, To H, von Dincklage J, Vuletich C, Watson DI, Yusoff IF.

J Gastroenterol Hepatol. 2015 May;30(5):804-20. doi: 10.1111/jgh.12913. Review.


International Consensus on Standardization of Data Collection for Complications Associated With Esophagectomy: Esophagectomy Complications Consensus Group (ECCG).

Low DE, Alderson D, Cecconello I, Chang AC, Darling GE, DʼJourno XB, Griffin SM, Hölscher AH, Hofstetter WL, Jobe BA, Kitagawa Y, Kucharczuk JC, Law SY, Lerut TE, Maynard N, Pera M, Peters JH, Pramesh CS, Reynolds JV, Smithers BM, van Lanschot JJ.

Ann Surg. 2015 Aug;262(2):286-94. doi: 10.1097/SLA.0000000000001098.


Supportive care needs, anxiety, depression and quality of life amongst newly diagnosed patients with localised invasive cutaneous melanoma in Queensland, Australia.

Beesley VL, Smithers BM, Khosrotehrani K, Khatun M, O'Rourke P, Hughes MC, Malt MK, Zonta MJ, Bayley GJ, Barbour AP, Brown LJ, D'Arcy J, Allan CP, Green AC.

Psychooncology. 2015 Jul;24(7):763-70. doi: 10.1002/pon.3718. Epub 2014 Oct 29.


Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis.

Nones K, Waddell N, Wayte N, Patch AM, Bailey P, Newell F, Holmes O, Fink JL, Quinn MCJ, Tang YH, Lampe G, Quek K, Loffler KA, Manning S, Idrisoglu S, Miller D, Xu Q, Waddell N, Wilson PJ, Bruxner TJC, Christ AN, Harliwong I, Nourse C, Nourbakhsh E, Anderson M, Kazakoff S, Leonard C, Wood S, Simpson PT, Reid LE, Krause L, Hussey DJ, Watson DI, Lord RV, Nancarrow D, Phillips WA, Gotley D, Smithers BM, Whiteman DC, Hayward NK, Campbell PJ, Pearson JV, Grimmond SM, Barbour AP.

Nat Commun. 2014 Oct 29;5:5224. doi: 10.1038/ncomms6224.


Phase 2 Study of Intralesional PV-10 in Refractory Metastatic Melanoma.

Thompson JF, Agarwala SS, Smithers BM, Ross MI, Scoggins CR, Coventry BJ, Neuhaus SJ, Minor DR, Singer JM, Wachter EA.

Ann Surg Oncol. 2015 Jul;22(7):2135-42. doi: 10.1245/s10434-014-4169-5. Epub 2014 Oct 28.


Changeable naevi in people at high risk for melanoma.

Abbott NC, Pandeya N, Ong N, McClenahan P, Smithers BM, Green A, Soyer HP.

Australas J Dermatol. 2015 Feb;56(1):14-8. doi: 10.1111/ajd.12181. Epub 2014 Aug 20.


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