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The Role of Neuronal Pentraxin 2 (NP2) in Regulating Glutamatergic Signaling and Neuropathology.

Chapman G, Shanmugalingam U, Smith PD.

Front Cell Neurosci. 2020 Jan 8;13:575. doi: 10.3389/fncel.2019.00575. eCollection 2019. Review.


Best Practices to Advance Health Literacy in a Wisconsin Adult Literacy Coalition.

Erikson M, Smith PD, Sparks SW.

Health Lit Res Pract. 2019 Oct 3;3(3 Suppl):S8-S14. doi: 10.3928/24748307-20190405-01. eCollection 2019 Jul.


Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors.

Sale MJ, Minihane E, Monks NR, Gilley R, Richards FM, Schifferli KP, Andersen CL, Davies EJ, Vicente MA, Ozono E, Markovets A, Dry JR, Drew L, Flemington V, Proia T, Jodrell DI, Smith PD, Cook SJ.

Nat Commun. 2019 Nov 14;10(1):5167. doi: 10.1038/s41467-019-12409-w.


Using normalisation process theory to understand workflow implications of decision support implementation across diverse primary care settings.

Mishuris RG, Palmisano J, McCullagh L, Hess R, Feldstein DA, Smith PD, McGinn T, Mann DM.

BMJ Health Care Inform. 2019 Oct;26(1). pii: e100088. doi: 10.1136/bmjhci-2019-100088.


One-carbon metabolism supplementation improves outcome after stroke in aged male MTHFR-deficient mice.

Jadavji NM, Mosnier H, Kelly E, Lawrence K, Cruickshank S, Stacey S, McCall A, Dhatt S, Arning E, Bottiglieri T, Smith PD.

Neurobiol Dis. 2019 Dec;132:104613. doi: 10.1016/j.nbd.2019.104613. Epub 2019 Sep 13.


Eradication of Helicobacter pylori in Children Restores the Structure of the Gastric Bacterial Community to That of Noninfected Children.

Serrano CA, Pierre R, Van Der Pol WJ, Morrow CD, Smith PD, Harris PR.

Gastroenterology. 2019 Dec;157(6):1673-1675. doi: 10.1053/j.gastro.2019.08.017. Epub 2019 Aug 20. No abstract available.


A cell-engineered system to assess tumor cell sensitivity to CD8+ T cell-mediated cytotoxicity.

Nelson N, Lopez-Pelaez M, Palazon A, Poon E, De La Roche M, Barry S, Valge-Archer V, Wilkinson RW, Dovedi SJ, Smith PD.

Oncoimmunology. 2019 Apr 26;8(8):1599635. doi: 10.1080/2162402X.2019.1599635. eCollection 2019.


Dental Students' Non-Clinical Learning During Community-Based Experiences: A Survey of U.S. Dental Schools.

Smith PD, Mays KA.

J Dent Educ. 2019 Nov;83(11):1289-1295. doi: 10.21815/JDE.019.130. Epub 2019 Jul 8.


Catalytic direct amidations in tert-butyl acetate using B(OCH2CF3)3.

Coomber CE, Laserna V, Martin LT, Smith PD, Hailes HC, Porter MJ, Sheppard TD.

Org Biomol Chem. 2019 Jul 14;17(26):6465-6469. doi: 10.1039/c9ob01012b. Epub 2019 Jun 21.


Discovery of a Thiadiazole-Pyridazine-Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models.

Finlay MRV, Anderton M, Bailey A, Boyd S, Brookfield J, Cairnduff C, Charles M, Cheasty A, Critchlow SE, Culshaw J, Ekwuru T, Hollingsworth I, Jones N, Leroux F, Littleson M, McCarron H, McKelvie J, Mooney L, Nissink JWM, Perkins D, Powell S, Quesada MJ, Raubo P, Sabin V, Smith J, Smith PD, Stark A, Ting A, Wang P, Wilson Z, Winter-Holt JJ, Wood JM, Wrigley GL, Yu G, Zhang P.

J Med Chem. 2019 Jul 25;62(14):6540-6560. doi: 10.1021/acs.jmedchem.9b00260. Epub 2019 Jul 16.


MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance.

Sale MJ, Balmanno K, Saxena J, Ozono E, Wojdyla K, McIntyre RE, Gilley R, Woroniuk A, Howarth KD, Hughes G, Dry JR, Arends MJ, Caro P, Oxley D, Ashton S, Adams DJ, Saez-Rodriguez J, Smith PD, Cook SJ.

Nat Commun. 2019 May 2;10(1):2030. doi: 10.1038/s41467-019-09438-w.


Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer.

Choi H, Deng J, Li S, Silk T, Dong L, Brea EJ, Houghton S, Redmond D, Zhong H, Boiarsky J, Akbay EA, Smith PD, Merghoub T, Wong KK, Wolchok JD.

Cell Rep. 2019 Apr 16;27(3):806-819.e5. doi: 10.1016/j.celrep.2019.03.066.


Live Usability Testing of Two Complex Clinical Decision Support Tools: Observational Study.

Richardson S, Feldstein D, McGinn T, Park LS, Khan S, Hess R, Smith PD, Mishuris RG, McCullagh L, Mann D.

JMIR Hum Factors. 2019 Apr 15;6(2):e12471. doi: 10.2196/12471.


Benefits and Challenges of Partner Site Engagement with Community-Based Dental Education Programs: The Partner Sites' Perspectives.

Smith PD, Thullen M, Evans C, Koerber A, Weatherspoon D.

J Dent Educ. 2019 Sep;83(9):1012-1018. doi: 10.21815/JDE.019.102. Epub 2019 Apr 8.


A cross sectional study to ascertain the incidence and causes of failure of oxygen delivery via Hudson Mask™ during recovery after anaesthesia.

Matusik M, Smith PD.

Anaesth Intensive Care. 2019 Jan;47(1):96-97. doi: 10.1177/0310057X18811728. Epub 2019 Feb 14. No abstract available.


Adaptive design of a clinical decision support tool: What the impact on utilization rates means for future CDS research.

Mann D, Hess R, McGinn T, Mishuris R, Chokshi S, McCullagh L, Smith PD, Palmisano J, Richardson S, Feldstein DA.

Digit Health. 2019 Feb 6;5:2055207619827716. doi: 10.1177/2055207619827716. eCollection 2019 Jan-Dec.


Paraquat Exposure Increases Oxidative Stress Within the Dorsal Striatum of Male Mice With a Genetic Deficiency in One-carbon Metabolism.

Jadavji NM, Murray LK, Emmerson JT, Rudyk CA, Hayley S, Smith PD.

Toxicol Sci. 2019 May 1;169(1):25-33. doi: 10.1093/toxsci/kfz034.


Design and rationale of a mixed methods randomized control trial: ADdressing Health literacy, bEliefs, adheRence and self-Efficacy (ADHERE) program to improve diabetes outcomes.

Shiyanbola OO, Walbrandt Pigarelli DL, Unni EJ, Smith PD, Maurer MA, Huang YM.

Contemp Clin Trials Commun. 2019 Jan 14;14:100326. doi: 10.1016/j.conctc.2019.100326. eCollection 2019 Jun.


CD103 (αE Integrin) Undergoes Endosomal Trafficking in Human Dendritic Cells, but Does Not Mediate Epithelial Adhesion.

Swain S, Roe MM, Sebrell TA, Sidar B, Dankoff J, VanAusdol R, Smythies LE, Smith PD, Bimczok D.

Front Immunol. 2018 Dec 21;9:2989. doi: 10.3389/fimmu.2018.02989. eCollection 2018.


If We Don't Ask, They Won't Tell: Screening for Urinary and Fecal Incontinence by Primary Care Providers.

Brown HW, Guan W, Schmuhl NB, Smith PD, Whitehead WE, Rogers RG.

J Am Board Fam Med. 2018 Sep-Oct;31(5):774-782. doi: 10.3122/jabfm.2018.05.180045.


Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547.

Kas SM, de Ruiter JR, Schipper K, Schut E, Bombardelli L, Wientjens E, Drenth AP, de Korte-Grimmerink R, Mahakena S, Phillips C, Smith PD, Klarenbeek S, van de Wetering K, Berns A, Wessels LFA, Jonkers J.

Cancer Res. 2018 Oct 1;78(19):5668-5679. doi: 10.1158/0008-5472.CAN-18-0757. Epub 2018 Aug 16.


Cytomegalovirus promotes intestinal macrophage-mediated mucosal inflammation through induction of Smad7.

Dennis EA, Smythies LE, Grabski R, Li M, Ballestas ME, Shimamura M, Sun JJ, Grams J, Stahl R, Niederweis ME, Britt WJ, Smith PD.

Mucosal Immunol. 2018 Nov;11(6):1694-1704. doi: 10.1038/s41385-018-0041-4. Epub 2018 Aug 3.


A genetic deficiency in folic acid metabolism impairs recovery after ischemic stroke.

Jadavji NM, Emmerson JT, Shanmugalingam U, MacFarlane AJ, Willmore WG, Smith PD.

Exp Neurol. 2018 Nov;309:14-22. doi: 10.1016/j.expneurol.2018.07.014. Epub 2018 Jul 25.


OBO-Protected Pyruvates as Reagents for the Synthesis of Functionalized Heteroaromatic Compounds.

Alves Esteves CH, Koyioni M, Christensen KE, Smith PD, Donohoe TJ.

Org Lett. 2018 Jul 6;20(13):4048-4051. doi: 10.1021/acs.orglett.8b01614. Epub 2018 Jun 15.


Quick screen of patients' numeracy and document literacy skills: the factor structure of the Newest Vital Sign.

Huang YM, Shiyanbola OO, Smith PD, Chan HY.

Patient Prefer Adherence. 2018 May 17;12:853-859. doi: 10.2147/PPA.S165994. eCollection 2018.


Association of health literacy and medication self-efficacy with medication adherence and diabetes control.

Huang YM, Shiyanbola OO, Smith PD.

Patient Prefer Adherence. 2018 May 10;12:793-802. doi: 10.2147/PPA.S153312. eCollection 2018.


Selumetinib-based therapy in uveal melanoma patient-derived xenografts.

Decaudin D, El Botty R, Diallo B, Massonnet G, Fleury J, Naguez A, Raymondie C, Davies E, Smith A, Wilson J, Howes C, Smith PD, Cassoux N, Piperno-Neumann S, Roman-Roman S, Némati F.

Oncotarget. 2018 Apr 24;9(31):21674-21686. doi: 10.18632/oncotarget.24670. eCollection 2018 Apr 24.


It's All about Timing: The Involvement of Kir4.1 Channel Regulation in Acute Ischemic Stroke Pathology.

Milton M, Smith PD.

Front Cell Neurosci. 2018 Feb 16;12:36. doi: 10.3389/fncel.2018.00036. eCollection 2018. Review.


Targeting CD14 on blood derived cells improves intracortical microelectrode performance.

Bedell HW, Hermann JK, Ravikumar M, Lin S, Rein A, Li X, Molinich E, Smith PD, Selkirk SM, Miller RH, Sidik S, Taylor DM, Capadona JR.

Biomaterials. 2018 May;163:163-173. doi: 10.1016/j.biomaterials.2018.02.014. Epub 2018 Feb 13.


Ongoing design concerns of portable oxygen cylinders.

Matusik MR, Smith PD.

Anaesth Intensive Care. 2018 Jan;46(1):136-137. No abstract available.


New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome.

Wilson LJ, Linley A, Hammond DE, Hood FE, Coulson JM, MacEwan DJ, Ross SJ, Slupsky JR, Smith PD, Eyers PA, Prior IA.

Cancer Res. 2018 Jan 1;78(1):15-29. doi: 10.1158/0008-5472.CAN-17-2291. Epub 2017 Dec 18. Review.


Recombinant growth differentiation factor 11 influences short-term memory and enhances Sox2 expression in middle-aged mice.

Zhang M, Jadavji NM, Yoo HS, Smith PD.

Behav Brain Res. 2018 Apr 2;341:45-49. doi: 10.1016/j.bbr.2017.12.019. Epub 2017 Dec 15.


Silver-Free Palladium-Catalyzed C(sp3)-H Arylation of Saturated Bicyclic Amine Scaffolds.

Coomber CE, Benhamou L, Bučar DK, Smith PD, Porter MJ, Sheppard TD.

J Org Chem. 2018 Mar 2;83(5):2495-2503. doi: 10.1021/acs.joc.7b02665. Epub 2017 Dec 19.


Yoga's effect on falls in rural, older adults.

Hamrick I, Mross P, Christopher N, Smith PD.

Complement Ther Med. 2017 Dec;35:57-63. doi: 10.1016/j.ctim.2017.09.007. Epub 2017 Sep 28.


Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt's lymphoma anti-tumor activity.

Curtis NJ, Mooney L, Hopcroft L, Michopoulos F, Whalley N, Zhong H, Murray C, Logie A, Revill M, Byth KF, Benjamin AD, Firth MA, Green S, Smith PD, Critchlow SE.

Oncotarget. 2017 May 25;8(41):69219-69236. doi: 10.18632/oncotarget.18215. eCollection 2017 Sep 19.


In the Age of Breast Augmentation, Breast Reconstruction Provides an Opportunity to Augment the Breast.

Zimmerman AL, Tugertimur B, Smith PD, Kumar A, Dayicioglu D.

Cancer Control. 2017 Oct-Dec;24(4):1073274817729064. doi: 10.1177/1073274817729064.


Early Postoperative Complications after Oncoplastic Reduction.

Mattingly AE, Ma Z, Smith PD, Kiluk JV, Khakpour N, Hoover SJ, Laronga C, Lee MC.

South Med J. 2017 Oct;110(10):660-666. doi: 10.14423/SMJ.0000000000000706.


Diskogenic Reactivation of Herpes Zoster.

Dhillon RS, Smith PD.

World Neurosurg. 2018 Jan;109:138-139. doi: 10.1016/j.wneu.2017.09.132. Epub 2017 Sep 27.


MCT1 Inhibitor AZD3965 Increases Mitochondrial Metabolism, Facilitating Combination Therapy and Noninvasive Magnetic Resonance Spectroscopy.

Beloueche-Babari M, Wantuch S, Casals Galobart T, Koniordou M, Parkes HG, Arunan V, Chung YL, Eykyn TR, Smith PD, Leach MO.

Cancer Res. 2017 Nov 1;77(21):5913-5924. doi: 10.1158/0008-5472.CAN-16-2686. Epub 2017 Sep 18.


Pyruvate Enolate Arylation and Alkylation: OBO Ester Protected Pyruvates as Useful Reagents in Organic Synthesis.

Alves Esteves CH, Hall CJJ, Smith PD, Donohoe TJ.

Org Lett. 2017 Oct 6;19(19):5248-5251. doi: 10.1021/acs.orglett.7b02524. Epub 2017 Sep 18.


The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment.

Poon E, Mullins S, Watkins A, Williams GS, Koopmann JO, Di Genova G, Cumberbatch M, Veldman-Jones M, Grosskurth SE, Sah V, Schuller A, Reimer C, Dovedi SJ, Smith PD, Stewart R, Wilkinson RW.

J Immunother Cancer. 2017 Aug 15;5(1):63. doi: 10.1186/s40425-017-0268-8.


Regional Assessment of Human Fecal Contamination in Southern California Coastal Drainages.

Cao Y, Raith MR, Smith PD, Griffith JF, Weisberg SB, Schriewer A, Sheldon A, Crompton C, Amenu GG, Gregory J, Guzman J, Goodwin KD, Othman L, Manasjan M, Choi S, Rapoport S, Steele S, Nguyen T, Yu X.

Int J Environ Res Public Health. 2017 Aug 4;14(8). pii: E874. doi: 10.3390/ijerph14080874.


Characterization of Human Blood Monocytes and Intestinal Macrophages.

Dennis EA, Robinson TO, Smythies LE, Smith PD.

Curr Protoc Immunol. 2017 Aug 1;118:14.3.1-14.3.14. doi: 10.1002/cpim.30.


Development of a falls reduction yoga program for older adults-A pilot study.

Smith PD, Mross P, Christopher N.

Complement Ther Med. 2017 Apr;31:118-126. doi: 10.1016/j.ctim.2017.01.007. Epub 2017 Feb 20.


B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke.

Jadavji NM, Emmerson JT, MacFarlane AJ, Willmore WG, Smith PD.

Neurobiol Dis. 2017 Jul;103:89-100. doi: 10.1016/j.nbd.2017.04.001. Epub 2017 Apr 7.


Catalytic Enolate Arylation with 3-Bromoindoles Allows the Formation of β-Carbolines.

Alves Esteves CH, Smith PD, Donohoe TJ.

J Org Chem. 2017 Apr 21;82(8):4435-4443. doi: 10.1021/acs.joc.7b00299. Epub 2017 Mar 31.


Complications and Recurrence in Implant-Sparing Oncologic Breast Surgery.

Elston JB, Prabhakaran S, Lleshi A, Castillo B, Sun W, Kumar A, Ma Z, Smith PD, Dayicioglu D.

Ann Plast Surg. 2017 Jun;78(6S Suppl 5):S269-S274. doi: 10.1097/SAP.0000000000001039.


Design and implementation of electronic health record integrated clinical prediction rules (iCPR): a randomized trial in diverse primary care settings.

Feldstein DA, Hess R, McGinn T, Mishuris RG, McCullagh L, Smith PD, Flynn M, Palmisano J, Doros G, Mann D.

Implement Sci. 2017 Mar 14;12(1):37. doi: 10.1186/s13012-017-0567-y.


Helicobacter pylori infection is associated with an altered gastric microbiota in children.

Brawner KM, Kumar R, Serrano CA, Ptacek T, Lefkowitz E, Morrow CD, Zhi D, Kyanam-Kabir-Baig KR, Smythies LE, Harris PR, Smith PD.

Mucosal Immunol. 2017 Sep;10(5):1169-1177. doi: 10.1038/mi.2016.131. Epub 2017 Jan 25.


Differential regulation of CD103 (αE integrin) expression in human dendritic cells by retinoic acid and Toll-like receptor ligands.

Roe MM, Swain S, Sebrell TA, Sewell MA, Collins MM, Perrino BA, Smith PD, Smythies LE, Bimczok D.

J Leukoc Biol. 2017 May;101(5):1169-1180. doi: 10.1189/jlb.1MA0316-131R. Epub 2017 Jan 13.

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