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Items: 1 to 50 of 320

1.

A mutation in Hnrnph1 that decreases methamphetamine-induced reinforcement, reward, and dopamine release and increases synaptosomal hnRNP H and mitochondrial proteins.

Ruan QT, Yazdani N, Blum BC, Beierle JA, Lin W, Coelho MA, Fultz EK, Healy AF, Shahin JR, Kandola AK, Luttik KP, Zheng K, Smith NJ, Cheung J, Mortazavi F, Apicco DJ, Ragu Varman D, Ramamoorthy S, Ash PEA, Rosene DL, Emili A, Wolozin B, Szumlinski KK, Bryant CD.

J Neurosci. 2019 Nov 8. pii: 1808-19. doi: 10.1523/JNEUROSCI.1808-19.2019. [Epub ahead of print]

PMID:
31704785
2.

High-throughput phenotyping of heteromeric human ether-à-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants.

Ng CA, Perry MD, Liang W, Smith NJ, Foo B, Shrier A, Lukacs GL, Hill AP, Vandenberg JI.

Heart Rhythm. 2019 Sep 23. pii: S1547-5271(19)30853-7. doi: 10.1016/j.hrthm.2019.09.020. [Epub ahead of print]

PMID:
31557540
3.

Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84.

Montgomery MK, Osborne B, Brandon AE, O'Reilly L, Fiveash CE, Brown SHJ, Wilkins BP, Samsudeen A, Yu J, Devanapalli B, Hertzog A, Tolun AA, Kavanagh T, Cooper AA, Mitchell TW, Biden TJ, Smith NJ, Cooney GJ, Turner N.

FASEB J. 2019 Nov;33(11):12264-12276. doi: 10.1096/fj.201900234R. Epub 2019 Aug 15.

PMID:
31415180
4.

Minimally invasive single-vessel left internal mammary to left anterior descending artery bypass grafting improves outcomes over conventional sternotomy: A single-institution retrospective cohort study.

Smith NJ, Miles B, Cain MT, Joyce LD, Pearson P, Joyce DL.

J Card Surg. 2019 Sep;34(9):788-795. doi: 10.1111/jocs.14144. Epub 2019 Jul 3.

PMID:
31269282
5.

Topological Control of Water Reactivity on Glass Surfaces: Evidence of a Chemically Stable Intermediate Phase.

Wilkinson CJ, Doss K, Hahn SH, Keilbart N, Potter AR, Smith NJ, Dabo I, van Duin ACT, Kim SH, Mauro JC.

J Phys Chem Lett. 2019 Jul 18;10(14):3955-3960. doi: 10.1021/acs.jpclett.9b01275. Epub 2019 Jul 2.

PMID:
31241951
6.

Cryo-EM reveals distinct conformations of E. coli ATP synthase on exposure to ATP.

Sobti M, Ishmukhametov R, Bouwer JC, Ayer A, Suarna C, Smith NJ, Christie M, Stocker R, Duncan TM, Stewart AG.

Elife. 2019 Mar 26;8. pii: e43864. doi: 10.7554/eLife.43864.

7.

The APOBEC3 genes and their role in cancer: insights from human papillomavirus.

Smith NJ, Fenton TR.

J Mol Endocrinol. 2019 Mar 1. pii: JME-19-0011.R1. doi: 10.1530/JME-19-0011. [Epub ahead of print] Review.

PMID:
30870810
8.

Development of highly inhomogeneous temperature profile within electrically heated alkali silicate glasses.

McLaren CT, Kopatz C, Smith NJ, Jain H.

Sci Rep. 2019 Feb 26;9(1):2805. doi: 10.1038/s41598-019-39431-8.

9.

A Comparison of Dietary and Caloric Restriction Models on Body Composition, Physical Performance, and Metabolic Health in Young Mice.

Smith NJ, Caldwell JL, van der Merwe M, Sharma S, Butawan M, Puppa M, Bloomer RJ.

Nutrients. 2019 Feb 7;11(2). pii: E350. doi: 10.3390/nu11020350.

10.

Structural and Chemical Approach toward Understanding the Aqueous Corrosion of Sodium Aluminoborate Glasses.

Kapoor S, Youngman RE, Zakharchuk K, Yaremchenko A, Smith NJ, Goel A.

J Phys Chem B. 2018 Dec 6;122(48):10913-10927. doi: 10.1021/acs.jpcb.8b06155. Epub 2018 Nov 26.

PMID:
30403142
11.

First Results from the DEAP-3600 Dark Matter Search with Argon at SNOLAB.

Amaudruz PA, Baldwin M, Batygov M, Beltran B, Bina CE, Bishop D, Bonatt J, Boorman G, Boulay MG, Broerman B, Bromwich T, Bueno JF, Burghardt PM, Butcher A, Cai B, Chan S, Chen M, Chouinard R, Cleveland BT, Cranshaw D, Dering K, DiGioseffo J, Dittmeier S, Duncan FA, Dunford M, Erlandson A, Fatemighomi N, Florian S, Flower A, Ford RJ, Gagnon R, Giampa P, Golovko VV, Gorel P, Gornea R, Grace E, Graham K, Gulyev E, Hakobyan R, Hall A, Hallin AL, Hamstra M, Harvey PJ, Hearns C, Jillings CJ, Kamaev O, Kemp A, Kuźniak M, Langrock S, La Zia F, Lehnert B, Lidgard JJ, Lim C, Lindner T, Linn Y, Liu S, Majewski P, Mathew R, McDonald AB, McElroy T, McGinn T, McLaughlin JB, Mead S, Mehdiyev R, Mielnichuk C, Monroe J, Muir A, Nadeau P, Nantais C, Ng C, Noble AJ, O'Dwyer E, Ohlmann C, Olchanski K, Olsen KS, Ouellet C, Pasuthip P, Peeters SJM, Pollmann TR, Rand ET, Rau W, Rethmeier C, Retière F, Seeburn N, Shaw B, Singhrao K, Skensved P, Smith B, Smith NJT, Sonley T, Soukup J, Stainforth R, Stone C, Strickland V, Sur B, Tang J, Taylor J, Veloce L, Vázquez-Jáuregui E, Walding J, Ward M, Westerdale S, Woolsey E, Zielinski J; DEAP-3600 Collaboration.

Phys Rev Lett. 2018 Aug 17;121(7):071801. doi: 10.1103/PhysRevLett.121.071801.

PMID:
30169081
12.

Corrigendum to "Prevention of the Severity of Post-ischemic Inflammation and Brain Damage by Simultaneous Knockdown of Toll-like Receptors 2 and 4" [Neuroscience 373 (2018) 82-91].

Nalamolu KR, Smith NJ, Chelluboina B, Klopfenstein JD, Pinson DM, Wang DZ, Vemuganti R, Veeravalli KK.

Neuroscience. 2018 Aug 1;384:429. doi: 10.1016/j.neuroscience.2018.05.038. Epub 2018 Jun 5. No abstract available.

PMID:
29879419
13.

Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control.

Coleman JLJ, Mouat MA, Wu J, Jancovski N, Bassi JK, Chan AY, Humphreys DT, Mrad N, Yu ZY, Ngo T, Iismaa S, Dos Remedios CG, Feneley MP, Allen AM, Graham RM, Smith NJ.

Biol Sex Differ. 2018 Apr 6;9(1):14. doi: 10.1186/s13293-018-0173-y.

14.

Fast, irreversible modification of cysteines through strain releasing conjugate additions of cyclopropenyl ketones.

Smith NJ, Rohlfing K, Sawicki LA, Kharkar PM, Boyd SJ, Kloxin AM, Fox JM.

Org Biomol Chem. 2018 Mar 28;16(12):2164-2169. doi: 10.1039/c8ob00166a. Epub 2018 Mar 9.

15.

GPCRs in context: sexual dimorphism in the cardiovascular system.

Mouat MA, Coleman JLJ, Smith NJ.

Br J Pharmacol. 2018 Nov;175(21):4047-4059. doi: 10.1111/bph.14160. Epub 2018 Mar 25. Review.

16.

GPR65 inhibits experimental autoimmune encephalomyelitis through CD4+ T cell independent mechanisms that include effects on iNKT cells.

Wirasinha RC, Vijayan D, Smith NJ, Parnell GP, Swarbrick A, Brink R, King C, Stewart G, Booth DR, Batten M.

Immunol Cell Biol. 2018 Feb;96(2):128-136. doi: 10.1111/imcb.1031. Epub 2017 Dec 19.

PMID:
29363187
17.

Prevention of the Severity of Post-ischemic Inflammation and Brain Damage by Simultaneous Knockdown of Toll-like Receptors 2 and 4.

Nalamolu KR, Smith NJ, Chelluboina B, Klopfenstein JD, Pinson DM, Wang DZ, Vemuganti R, Veeravalli KK.

Neuroscience. 2018 Mar 1;373:82-91. doi: 10.1016/j.neuroscience.2018.01.014. Epub 2018 Jan 12. Erratum in: Neuroscience. 2018 Aug 1;384:429.

PMID:
29337240
18.

Effect of Temperature on the Size Distribution, Shell Properties, and Stability of Definity®.

Shekhar H, Smith NJ, Raymond JL, Holland CK.

Ultrasound Med Biol. 2018 Feb;44(2):434-446. doi: 10.1016/j.ultrasmedbio.2017.09.021. Epub 2017 Nov 22.

19.

Understanding the structural drivers governing glass-water interactions in borosilicate based model bioactive glasses.

Stone-Weiss N, Pierce EM, Youngman RE, Gulbiten O, Smith NJ, Du J, Goel A.

Acta Biomater. 2018 Jan;65:436-449. doi: 10.1016/j.actbio.2017.11.006. Epub 2017 Nov 7.

PMID:
29127067
20.

Studies of Physical Education in the United States Using SOFIT: A Review.

McKenzie TL, Smith NJ.

Res Q Exerc Sport. 2017 Dec;88(4):492-502. doi: 10.1080/02701367.2017.1376028. Epub 2017 Oct 24. Review.

PMID:
29064778
21.

LAGOS-NE: a multi-scaled geospatial and temporal database of lake ecological context and water quality for thousands of US lakes.

Soranno PA, Bacon LC, Beauchene M, Bednar KE, Bissell EG, Boudreau CK, Boyer MG, Bremigan MT, Carpenter SR, Carr JW, Cheruvelil KS, Christel ST, Claucherty M, Collins SM, Conroy JD, Downing JA, Dukett J, Fergus CE, Filstrup CT, Funk C, Gonzalez MJ, Green LT, Gries C, Halfman JD, Hamilton SK, Hanson PC, Henry EN, Herron EM, Hockings C, Jackson JR, Jacobson-Hedin K, Janus LL, Jones WW, Jones JR, Keson CM, King KBS, Kishbaugh SA, Lapierre JF, Lathrop B, Latimore JA, Lee Y, Lottig NR, Lynch JA, Matthews LJ, McDowell WH, Moore KEB, Neff BP, Nelson SJ, Oliver SK, Pace ML, Pierson DC, Poisson AC, Pollard AI, Post DM, Reyes PO, Rosenberry DO, Roy KM, Rudstam LG, Sarnelle O, Schuldt NJ, Scott CE, Skaff NK, Smith NJ, Spinelli NR, Stachelek JJ, Stanley EH, Stoddard JL, Stopyak SB, Stow CA, Tallant JM, Tan PN, Thorpe AP, Vanni MJ, Wagner T, Watkins G, Weathers KC, Webster KE, White JD, Wilmes MK, Yuan S.

Gigascience. 2017 Dec 1;6(12):1-22. doi: 10.1093/gigascience/gix101.

22.

Reduced cerebral vascularization in experimental neuronopathic Gaucher disease.

Smith NJ, Fuller M, Saville JT, Cox TM.

J Pathol. 2018 Jan;244(1):120-128. doi: 10.1002/path.4992.

PMID:
28981147
23.

Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy.

Eichler F, Duncan C, Musolino PL, Orchard PJ, De Oliveira S, Thrasher AJ, Armant M, Dansereau C, Lund TC, Miller WP, Raymond GV, Sankar R, Shah AJ, Sevin C, Gaspar HB, Gissen P, Amartino H, Bratkovic D, Smith NJC, Paker AM, Shamir E, O'Meara T, Davidson D, Aubourg P, Williams DA.

N Engl J Med. 2017 Oct 26;377(17):1630-1638. doi: 10.1056/NEJMoa1700554. Epub 2017 Oct 4.

24.

Development of an Intelligent Spacer Data Logger System.

O'Callaghan C, Smith NJ, Barry PW, Denyer J.

J Aerosol Med Pulm Drug Deliv. 2017 Dec;30(6):444-450. doi: 10.1089/jamp.2017.1375. Epub 2017 Aug 28.

PMID:
28846487
25.

Chronic Exposure to Methamphetamine Disrupts Reinforcement-Based Decision Making in Rats.

Groman SM, Rich KM, Smith NJ, Lee D, Taylor JR.

Neuropsychopharmacology. 2018 Mar;43(4):770-780. doi: 10.1038/npp.2017.159. Epub 2017 Jul 25.

26.

Epithelial Na+ channel inhibitors for the treatment of cystic fibrosis.

Smith NJ, Solovay CF.

Pharm Pat Anal. 2017 Jul;6(4):179-188. doi: 10.4155/ppa-2017-0009. Epub 2017 Jul 11.

PMID:
28696180
27.

Temporal parameters of post-stress prophylactic glucose treatment in rats.

Conoscenti MA, Hart EE, Smith NJ, Minor TR.

Stress. 2017 May;20(3):265-276. doi: 10.1080/10253890.2017.1334052. Epub 2017 Jun 20.

PMID:
28532277
28.

Bootstrapping language acquisition.

Abend O, Kwiatkowski T, Smith NJ, Goldwater S, Steedman M.

Cognition. 2017 Jul;164:116-143. doi: 10.1016/j.cognition.2017.02.009. Epub 2017 Apr 13.

PMID:
28412593
29.

The G protein-coupled receptor N-terminus and receptor signalling: N-tering a new era.

Coleman JL, Ngo T, Smith NJ.

Cell Signal. 2017 May;33:1-9. doi: 10.1016/j.cellsig.2017.02.004. Epub 2017 Feb 8. Review.

PMID:
28188824
30.

Quantification of plasma sulfatides by mass spectrometry: Utility for metachromatic leukodystrophy.

Saville JT, Smith NJ, Fletcher JM, Fuller M.

Anal Chim Acta. 2017 Feb 22;955:79-85. doi: 10.1016/j.aca.2016.12.002. Epub 2016 Dec 19.

PMID:
28088283
31.

Relational aggression and marital quality: A five-year longitudinal study.

Coyne SM, Nelson DA, Carroll JS, Smith NJ, Yang C, Holmgren HG, Johnson C.

J Fam Psychol. 2017 Apr;31(3):282-293. doi: 10.1037/fam0000274. Epub 2017 Jan 5.

PMID:
28054802
32.

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

Ngo T, Ilatovskiy AV, Stewart AG, Coleman JL, McRobb FM, Riek RP, Graham RM, Abagyan R, Kufareva I, Smith NJ.

Nat Chem Biol. 2017 Feb;13(2):235-242. doi: 10.1038/nchembio.2266. Epub 2016 Dec 19.

33.

Novel hyperkinetic dystonia-like manifestation and neurological disease course of Swedish Gaucher patients.

Machaczka M, Paucar M, Björkvall CK, Smith NJC, Cox TM, Forsgren L, Svenningsson P.

Blood Cells Mol Dis. 2018 Feb;68:86-92. doi: 10.1016/j.bcmd.2016.10.011. Epub 2016 Oct 21.

PMID:
27789132
34.

Early surgical intervention in type I laryngeal cleft.

Day KE, Smith NJ, Kulbersh BD.

Int J Pediatr Otorhinolaryngol. 2016 Nov;90:236-240. doi: 10.1016/j.ijporl.2016.09.017. Epub 2016 Sep 14.

PMID:
27729141
35.

Closure of a Traumatic Esophagomediastinal Fistula in a Child by Endoscopic Fulguration and Fibrin Injection.

Maizlin II, Chen JS, Smith NJ, Rogers DA.

Am Surg. 2016 Sep;82(9):789-91.

PMID:
27670565
36.

Programmable Wrinkling of Self-Assembled Nanoparticle Films on Shape Memory Polymers.

Gabardo CM, Yang J, Smith NJ, Adams-McGavin RC, Soleymani L.

ACS Nano. 2016 Sep 27;10(9):8829-36. doi: 10.1021/acsnano.6b04584. Epub 2016 Sep 13.

PMID:
27608141
37.

Physician Consolidation: Rapid Movement From Small To Large Group Practices, 2013-15.

Muhlestein DB, Smith NJ.

Health Aff (Millwood). 2016 Sep 1;35(9):1638-42. doi: 10.1377/hlthaff.2016.0130.

PMID:
27605644
38.

BRAT1-associated neurodegeneration: Intra-familial phenotypic differences in siblings.

Smith NJ, Lipsett J, Dibbens LM, Heron SE.

Am J Med Genet A. 2016 Nov;170(11):3033-3038. doi: 10.1002/ajmg.a.37853. Epub 2016 Aug 2.

PMID:
27480663
39.

Dopamine D3 Receptor Availability Is Associated with Inflexible Decision Making.

Groman SM, Smith NJ, Petrullli JR, Massi B, Chen L, Ropchan J, Huang Y, Lee D, Morris ED, Taylor JR.

J Neurosci. 2016 Jun 22;36(25):6732-41. doi: 10.1523/JNEUROSCI.3253-15.2016.

40.

Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity.

Coleman JL, Ngo T, Schmidt J, Mrad N, Liew CK, Jones NM, Graham RM, Smith NJ.

Sci Signal. 2016 Apr 12;9(423):ra36. doi: 10.1126/scisignal.aad1089.

PMID:
27072655
41.

Role of miRNAs and alternative mRNA 3'-end cleavage and polyadenylation of their mRNA targets in cardiomyocyte hypertrophy.

Soetanto R, Hynes CJ, Patel HR, Humphreys DT, Evers M, Duan G, Parker BJ, Archer SK, Clancy JL, Graham RM, Beilharz TH, Smith NJ, Preiss T.

Biochim Biophys Acta. 2016 May;1859(5):744-56. doi: 10.1016/j.bbagrm.2016.03.010. Epub 2016 Mar 24.

PMID:
27032571
42.

Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes.

McNamara JW, Li A, Smith NJ, Lal S, Graham RM, Kooiker KB, van Dijk SJ, Remedios CGD, Harris SP, Cooke R.

J Mol Cell Cardiol. 2016 May;94:65-71. doi: 10.1016/j.yjmcc.2016.03.009. Epub 2016 Mar 26.

43.

A Molecular Mechanism for Sequential Activation of a G Protein-Coupled Receptor.

Grundmann M, Tikhonova IG, Hudson BD, Smith NJ, Mohr K, Ulven T, Milligan G, Kenakin T, Kostenis E.

Cell Chem Biol. 2016 Mar 17;23(3):392-403. doi: 10.1016/j.chembiol.2016.02.014.

44.

Niclosamide blocks glucagon phosphorylation of Ser552 on β-catenin in primary rat hepatocytes via PKA signalling.

Chowdhury MK, Wu LE, Coleman JL, Smith NJ, Morris MJ, Shepherd PR, Smith GC.

Biochem J. 2016 May 1;473(9):1247-55. doi: 10.1042/BCJ20160121. Epub 2016 Mar 10.

PMID:
26964897
45.

Identifying ligands at orphan GPCRs: current status using structure-based approaches.

Ngo T, Kufareva I, Coleman JLj, Graham RM, Abagyan R, Smith NJ.

Br J Pharmacol. 2016 Oct;173(20):2934-51. doi: 10.1111/bph.13452. Epub 2016 Mar 5. Review.

46.

Super Mario brothers and sisters: Associations between coplaying video games and sibling conflict and affection.

Coyne SM, Jensen AC, Smith NJ, Erickson DH.

J Adolesc. 2016 Feb;47:48-59. doi: 10.1016/j.adolescence.2015.12.001. Epub 2015 Dec 31.

PMID:
26748076
47.

Drug Discovery Opportunities at the Endothelin B Receptor-Related Orphan G Protein-Coupled Receptors, GPR37 and GPR37L1.

Smith NJ.

Front Pharmacol. 2015 Nov 17;6:275. doi: 10.3389/fphar.2015.00275. eCollection 2015. Review.

48.

The human urothelial tight junction: claudin 3 and the ZO-1α+ switch.

Smith NJ, Hinley J, Varley CL, Eardley I, Trejdosiewicz LK, Southgate J.

Bladder (San Franc). 2015;2(1):e9.

49.

Learning to ensure patient safety in clinical settings: comparing Finnish and British nursing students' perceptions.

Tella S, Smith NJ, Partanen P, Jamookeeah D, Lamidi ML, Turunen H.

J Clin Nurs. 2015 Oct;24(19-20):2954-64. doi: 10.1111/jocn.12914. Epub 2015 Jul 27.

PMID:
26216053
50.

Rapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case Study.

Coleman JL, Brennan K, Ngo T, Balaji P, Graham RM, Smith NJ.

Front Endocrinol (Lausanne). 2015 Jun 30;6:105. doi: 10.3389/fendo.2015.00105. eCollection 2015.

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